ATE513925T1 - Verfahren zum de-novo-nachweis von sequenzen in nukleinsäuren: zielsequenzierung durch fragmentierung - Google Patents

Verfahren zum de-novo-nachweis von sequenzen in nukleinsäuren: zielsequenzierung durch fragmentierung

Info

Publication number
ATE513925T1
ATE513925T1 AT05733836T AT05733836T ATE513925T1 AT E513925 T1 ATE513925 T1 AT E513925T1 AT 05733836 T AT05733836 T AT 05733836T AT 05733836 T AT05733836 T AT 05733836T AT E513925 T1 ATE513925 T1 AT E513925T1
Authority
AT
Austria
Prior art keywords
nucleic acid
sequences
sequence
fragmentation
target
Prior art date
Application number
AT05733836T
Other languages
English (en)
Inventor
Charles Cantor
Fouad Siddiqi
Original Assignee
Univ Boston
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Boston filed Critical Univ Boston
Application granted granted Critical
Publication of ATE513925T1 publication Critical patent/ATE513925T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6872—Methods for sequencing involving mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT05733836T 2004-04-09 2005-04-08 Verfahren zum de-novo-nachweis von sequenzen in nukleinsäuren: zielsequenzierung durch fragmentierung ATE513925T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56328304P 2004-04-09 2004-04-09
US56528404P 2004-04-26 2004-04-26
PCT/US2005/011812 WO2005100607A1 (en) 2004-04-09 2005-04-08 Method for de novo detection of sequences in nucleic acids:target sequencing by fragmentation

Publications (1)

Publication Number Publication Date
ATE513925T1 true ATE513925T1 (de) 2011-07-15

Family

ID=35150018

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05733836T ATE513925T1 (de) 2004-04-09 2005-04-08 Verfahren zum de-novo-nachweis von sequenzen in nukleinsäuren: zielsequenzierung durch fragmentierung

Country Status (7)

Country Link
US (2) US7470517B2 (de)
EP (1) EP1740719B1 (de)
CN (1) CN1977053A (de)
AT (1) ATE513925T1 (de)
AU (2) AU2005233598B2 (de)
CA (1) CA2562557A1 (de)
WO (1) WO2005100607A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7470517B2 (en) * 2004-04-09 2008-12-30 Trustees Of Boston University Method for de novo detection of sequences in nucleic acids: target sequencing by fragmentation
DK1907571T3 (en) 2005-06-15 2017-08-21 Complete Genomics Inc NUCLEIC ACID ANALYSIS USING INCIDENTAL MIXTURES OF NON-OVERLAPPING FRAGMENTS
EP2145180B1 (de) * 2007-04-13 2013-12-04 Sequenom, Inc. Vergleichende sequenzanalyseverfahren und -systeme
AU2008254986A1 (en) * 2007-05-14 2008-11-27 Insight Genetics, Inc. Methods of screening nucleic acids for single nucleotide variations
US8592150B2 (en) 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
CN101251511B (zh) * 2008-03-14 2012-06-06 毅新兴业（北京）科技有限公司 一种利用限制性内切酶双酶切检测snp的方法
CN101251510B (zh) * 2008-03-14 2012-06-06 毅新兴业（北京）科技有限公司 一种联合限制性酶切法和质谱法以检测snp的方法
CN101246142B (zh) * 2008-04-03 2012-06-20 毅新兴业（北京）科技有限公司 一种检测单核苷酸多态性的方法
US9524369B2 (en) 2009-06-15 2016-12-20 Complete Genomics, Inc. Processing and analysis of complex nucleic acid sequence data
WO2011137368A2 (en) 2010-04-30 2011-11-03 Life Technologies Corporation Systems and methods for analyzing nucleic acid sequences
US9268903B2 (en) 2010-07-06 2016-02-23 Life Technologies Corporation Systems and methods for sequence data alignment quality assessment
US20160153060A1 (en) * 2013-07-09 2016-06-02 Tech-Knowhow Corp. Method for species identification by using molecular weights of nucleic acid cleavage fragments
CN103667491A (zh) * 2013-12-13 2014-03-26 中国科学院苏州生物医学工程技术研究所 一种核酸测序方法
EP3724355A1 (de) * 2017-12-15 2020-10-21 Novartis AG Polya-schwanzlängenanalyse der rna mittels massenspektrometrie

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458945B1 (en) 1998-10-01 2002-10-01 Variagenics, Inc. Method for analyzing polynucleotides
US6610492B1 (en) 1998-10-01 2003-08-26 Variagenics, Inc. Base-modified nucleotides and cleavage of polynucleotides incorporating them
US6566059B1 (en) 1998-10-01 2003-05-20 Variagenics, Inc. Method for analyzing polynucleotides
DE60020830T2 (de) 1999-04-30 2006-07-27 Sequenom, Inc., San Diego Diagnostische sequenzierung durch eine kombination von spezifischer spaltung und massenspektrometrie
US7060440B1 (en) 1999-09-01 2006-06-13 Yeda Research And Development Co. Ltd. Template-dependent nucleic acid polymerization using oligonucleotide triphosphates building blocks
US6287778B1 (en) 1999-10-19 2001-09-11 Affymetrix, Inc. Allele detection using primer extension with sequence-coded identity tags
GB9929381D0 (en) 1999-12-10 2000-02-09 Pyrosequencing Ab A method of assessing the amount of nucleic acid in a sample
AU2001268468A1 (en) 2000-06-13 2001-12-24 The Trustees Of Boston University Use of nucleotide analogs in the analysis of oligonucleotide mixtures and in highly multiplexed nucleic acid sequencing
AU2003215083A1 (en) 2002-02-06 2003-09-02 Tethys Bioscience, Inc. Method and apparatus for validating dna sequences without sequencing
JP4683922B2 (ja) 2002-09-06 2011-05-18 トラスティーズ オブ ボストン ユニバーシティ 遺伝子発現の定量方法
WO2004065617A2 (en) 2003-01-17 2004-08-05 The Trustees Of Boston University Haplotype analysis
AU2004270220B2 (en) 2003-09-05 2009-03-05 The Chinese University Of Hong Kong Method for non-invasive prenatal diagnosis
EP1689884A4 (de) 2003-10-08 2007-04-04 Univ Boston Verfahren zur pränatalen diagnose chromosomaler abnormalitäten
US7709262B2 (en) 2004-02-18 2010-05-04 Trustees Of Boston University Method for detecting and quantifying rare mutations/polymorphisms
US7470517B2 (en) * 2004-04-09 2008-12-30 Trustees Of Boston University Method for de novo detection of sequences in nucleic acids: target sequencing by fragmentation
US7901208B2 (en) * 2006-10-20 2011-03-08 Ultradent Products, Inc. Chemically impregnated absorbent gingival retraction cord comprising silk

Also Published As

Publication number Publication date
EP1740719A4 (de) 2008-03-05
EP1740719B1 (de) 2011-06-22
WO2005100607A1 (en) 2005-10-27
US20090075288A1 (en) 2009-03-19
US7470517B2 (en) 2008-12-30
AU2005233598A1 (en) 2005-10-27
CA2562557A1 (en) 2005-10-27
HK1098794A1 (en) 2007-07-27
AU2005233598B2 (en) 2010-09-30
US20080096194A1 (en) 2008-04-24
EP1740719A1 (de) 2007-01-10
CN1977053A (zh) 2007-06-06
AU2010212334A1 (en) 2010-09-09
US7807375B2 (en) 2010-10-05

Similar Documents

Publication Publication Date Title
DE602004021235D1 (de) Verfahren, kits und reagenzien zur nukleinsäuresequenzierung
JP2022548957A (ja) キャップガイド及びｒｎａマッピングのためのその使用方法
WO2004081228A3 (en) Real time gene expression profiling
SE0301951D0 (sv) New method
SG170028A1 (en) High throughput genome sequencing on dna arrays
DE69701671D1 (de) Verfahren und zusammenstellungen zur sequenzbestimmung von nukleinsäuremolekulen
WO2007133831A3 (en) High throughput genome sequencing on dna arrays
DE60142709D1 (de) Methoden und zusammensetzungen zur generierung einer vielzahl von kopien von nukleinsäuresequenzen und methoden zur detektion derselben
ATE515488T1 (de) Click-chemie zur herstellung von reportermolekülen
PL1649051T3 (pl) Wyznaczanie sekwencji polinukleotydowych
WO2003027328A3 (en) Methods, kits and compositions pertaining to the suppression of detectable probe binding to randomly distributed repeat sequences in genomic nucleic acid
BR9914262A (pt) Método para analisar polinucleotìdeos
CN111386362A (zh) 一种体液游离dna的文库构建方法及其应用
ATE546550T1 (de) Verfahren zum nachweis von hpv sowie sonden, primer und kits
DE602008003757D1 (de) Auswahl und anreicherung von proteinen durch in-vitro-untergliederung
CN103060429A (zh) 一种天赋潜能评估的飞行质谱生物芯片及其检测方法
CN101824412A (zh) 一种针对一个或多个目标基因组区域进行边扩增边连接的方法
MX2024008473A (es) Metodos y composiciones para deteccion y analisis rapidos de metilacion de citosina de arn y adn.
DK1546354T3 (da) Analytdetektion
ATE487799T1 (de) Multiplexanalyse von nukleinsäuren zur bestimmung von genotypen des humanen papillomavirus
CN103667252A (zh) 一种核酸扩增方法
DE602004019059D1 (de) Methode zur linearen nicht-selektiven amplifikation von nukleinsäuren
ES2875758T3 (es) Conjunto de cebadores y método para la detección e identificación de especies de mejillón del genero mytilus
CN108148913A (zh) 一种快速鉴别日本条鳎和缨鳞条鳎的分子生物学方法
EA202191888A1 (ru) Способ определения происхождения нуклеиновых кислот в смешанном образце

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties