ATE514710T1 - Akap18 delta, eine neue spleissvariante eines proteinkinase a-ankerproteins und verwendung dieser - Google Patents
Akap18 delta, eine neue spleissvariante eines proteinkinase a-ankerproteins und verwendung dieserInfo
- Publication number
- ATE514710T1 ATE514710T1 AT03750490T AT03750490T ATE514710T1 AT E514710 T1 ATE514710 T1 AT E514710T1 AT 03750490 T AT03750490 T AT 03750490T AT 03750490 T AT03750490 T AT 03750490T AT E514710 T1 ATE514710 T1 AT E514710T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- akap
- pka
- vector
- akap18
- Prior art date
Links
- 102000008130 Cyclic AMP-Dependent Protein Kinases Human genes 0.000 title abstract 3
- 108010049894 Cyclic AMP-Dependent Protein Kinases Proteins 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 102100031906 A-kinase anchor protein 7 isoforms alpha and beta Human genes 0.000 title 1
- 101000774725 Homo sapiens A-kinase anchor protein 7 isoform gamma Proteins 0.000 title 1
- 101000774727 Homo sapiens A-kinase anchor protein 7 isoforms alpha and beta Proteins 0.000 title 1
- 230000003993 interaction Effects 0.000 abstract 2
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 238000007792 addition Methods 0.000 abstract 1
- 230000003178 anti-diabetic effect Effects 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 239000003472 antidiabetic agent Substances 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 230000001646 thyrotropic effect Effects 0.000 abstract 1
- 230000005945 translocation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10244072 | 2002-09-06 | ||
| DE10306085A DE10306085B4 (de) | 2002-09-06 | 2003-02-07 | Neue Spleißvariante eines Proteinkinase A-Ankerproteins und Verwendung dieser |
| PCT/EP2003/009892 WO2004022591A1 (de) | 2002-09-06 | 2003-09-05 | Akap18 delta, eine neue spleissvariante eines proteinkinase a-ankerproteins und verwendung dieser |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE514710T1 true ATE514710T1 (de) | 2011-07-15 |
Family
ID=31896286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03750490T ATE514710T1 (de) | 2002-09-06 | 2003-09-05 | Akap18 delta, eine neue spleissvariante eines proteinkinase a-ankerproteins und verwendung dieser |
Country Status (2)
| Country | Link |
|---|---|
| AT (1) | ATE514710T1 (de) |
| DE (1) | DE10306085B4 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004031579B4 (de) * | 2004-06-29 | 2012-12-27 | Forschungsverbund Berlin E.V. | Peptide zur Inhibition der Interaktion von Proteinkinase A und Proteinkinase A-Ankerproteinen, diese umfassendes Nukleinsäuremolekül, Vektor, Wirtszelle, gegen diese gerichtetes Erkennungsmolekül, diese enthaltende pharmazeutische Zusammensetzung, diese enthaltender Kit und deren Verwendung |
| CN109406769A (zh) * | 2018-09-28 | 2019-03-01 | 李军 | Akr在min6细胞中胰岛素分泌机制研究的应用 |
-
2003
- 2003-02-07 DE DE10306085A patent/DE10306085B4/de not_active Expired - Fee Related
- 2003-09-05 AT AT03750490T patent/ATE514710T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| DE10306085B4 (de) | 2007-01-11 |
| DE10306085A1 (de) | 2004-03-25 |
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