ATE516496T1 - Verfahren zur in-vivo-suche nach kardiotoxischen substanzen mit teleost - Google Patents
Verfahren zur in-vivo-suche nach kardiotoxischen substanzen mit teleostInfo
- Publication number
- ATE516496T1 ATE516496T1 AT07701967T AT07701967T ATE516496T1 AT E516496 T1 ATE516496 T1 AT E516496T1 AT 07701967 T AT07701967 T AT 07701967T AT 07701967 T AT07701967 T AT 07701967T AT E516496 T1 ATE516496 T1 AT E516496T1
- Authority
- AT
- Austria
- Prior art keywords
- teleost
- vivo
- search
- cardiotoxic substances
- cardiotoxic
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 231100000457 cardiotoxic Toxicity 0.000 title 1
- 230000001451 cardiotoxic effect Effects 0.000 title 1
- 238000001727 in vivo Methods 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- 206010048610 Cardiotoxicity Diseases 0.000 abstract 1
- 230000004075 alteration Effects 0.000 abstract 1
- 231100000259 cardiotoxicity Toxicity 0.000 abstract 1
- 210000002257 embryonic structure Anatomy 0.000 abstract 1
- 230000004217 heart function Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/4603—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates from fish
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/326—Arrhythmias, e.g. ventricular fibrillation, tachycardia, atrioventricular block, torsade de pointes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2007/000035 WO2008086646A1 (en) | 2007-01-08 | 2007-01-08 | Method of in vivo screening for cardiac toxic agents using teleost |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE516496T1 true ATE516496T1 (de) | 2011-07-15 |
Family
ID=39635628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07701967T ATE516496T1 (de) | 2007-01-08 | 2007-01-08 | Verfahren zur in-vivo-suche nach kardiotoxischen substanzen mit teleost |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9535057B2 (de) |
| EP (1) | EP2115462B1 (de) |
| CN (1) | CN101646941B (de) |
| AT (1) | ATE516496T1 (de) |
| ES (1) | ES2369986T3 (de) |
| WO (1) | WO2008086646A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103063630B (zh) * | 2012-12-19 | 2016-03-30 | 山东省科学院生物研究所 | 一种影响骨骼矿化作用药物的筛选系统 |
| US9659391B1 (en) | 2016-03-31 | 2017-05-23 | Servicenow, Inc. | Request resolution shaper in a networked system architecture |
| EP3255430B1 (de) * | 2016-06-08 | 2020-03-25 | Vitargent (International) Biotechnology Limited | Giftstoffassays für kosmetische produkte mittles teleost embyonen |
| KR102427969B1 (ko) * | 2020-02-03 | 2022-08-03 | 한국표준과학연구원 | 고속 디지털 홀로그래피를 이용한 독성 테스트를 위한 심박수 모니터링 방법 |
| US11992297B2 (en) * | 2020-02-03 | 2024-05-28 | Korea Research Institute Of Standards And Science | Monitoring method of heart rate for toxicity test using high-speed digital holography |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1160570A1 (de) * | 2000-05-27 | 2001-12-05 | ARTEMIS Pharmaceuticals GmbH | Verfahren zur identifizierung von agenzien und genen, die die kardiovaskuläre Funktion beeinflussen |
| JP2003052354A (ja) | 2001-07-18 | 2003-02-25 | Nagoya Industrial Science Research Inst | 魚類胚を用いるスクリーニング方法 |
| AU2003275283A1 (en) * | 2002-11-20 | 2004-06-18 | The General Hospital Corporation | Zebrafish assay |
| US20040143865A1 (en) * | 2002-12-06 | 2004-07-22 | Rubinstein Amy L. | Transgenic zebrafish models for angiogenesis |
| US20060018833A1 (en) * | 2004-04-07 | 2006-01-26 | Randall Murphy | Method and system for screening compounds for muscular and/or neurological activity in animals |
-
2007
- 2007-01-08 EP EP07701967A patent/EP2115462B1/de not_active Not-in-force
- 2007-01-08 US US12/224,577 patent/US9535057B2/en active Active
- 2007-01-08 WO PCT/CN2007/000035 patent/WO2008086646A1/en not_active Ceased
- 2007-01-08 AT AT07701967T patent/ATE516496T1/de not_active IP Right Cessation
- 2007-01-08 ES ES07701967T patent/ES2369986T3/es active Active
- 2007-01-08 CN CN200780049451.2A patent/CN101646941B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2115462B1 (de) | 2011-07-13 |
| EP2115462A4 (de) | 2010-03-03 |
| US9535057B2 (en) | 2017-01-03 |
| US20090232739A1 (en) | 2009-09-17 |
| WO2008086646A1 (en) | 2008-07-24 |
| EP2115462A1 (de) | 2009-11-11 |
| CN101646941B (zh) | 2014-06-11 |
| ES2369986T3 (es) | 2011-12-09 |
| CN101646941A (zh) | 2010-02-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |