ATE517346T1 - Gpr18 als biomarker für th1-vermittelte immunantwort - Google Patents
Gpr18 als biomarker für th1-vermittelte immunantwortInfo
- Publication number
- ATE517346T1 ATE517346T1 AT06724680T AT06724680T ATE517346T1 AT E517346 T1 ATE517346 T1 AT E517346T1 AT 06724680 T AT06724680 T AT 06724680T AT 06724680 T AT06724680 T AT 06724680T AT E517346 T1 ATE517346 T1 AT E517346T1
- Authority
- AT
- Austria
- Prior art keywords
- gpr18
- biomarker
- immune response
- mediated immune
- mediated
- Prior art date
Links
- 101000829761 Homo sapiens N-arachidonyl glycine receptor Proteins 0.000 title abstract 2
- 102100023414 N-arachidonyl glycine receptor Human genes 0.000 title abstract 2
- 239000000090 biomarker Substances 0.000 title 1
- 230000028993 immune response Effects 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 210000000447 Th1 cell Anatomy 0.000 abstract 1
- 230000020411 cell activation Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0508988.3A GB0508988D0 (en) | 2005-05-03 | 2005-05-03 | Organic compounds |
| PCT/EP2006/004096 WO2006117194A2 (en) | 2005-05-03 | 2006-05-02 | Gpr18 as a biomaker for th1 mediated immune response |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE517346T1 true ATE517346T1 (de) | 2011-08-15 |
Family
ID=34674238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06724680T ATE517346T1 (de) | 2005-05-03 | 2006-05-02 | Gpr18 als biomarker für th1-vermittelte immunantwort |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090208997A1 (de) |
| EP (1) | EP1880219B1 (de) |
| JP (1) | JP2008540361A (de) |
| AT (1) | ATE517346T1 (de) |
| ES (1) | ES2370035T3 (de) |
| GB (1) | GB0508988D0 (de) |
| WO (1) | WO2006117194A2 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5433189B2 (ja) * | 2007-09-28 | 2014-03-05 | 承一 尾崎 | Mpo−anca関連血管炎の被験者に対する治療の効果を予測する材料を提供する方法 |
| CN108241054B (zh) * | 2017-12-26 | 2021-03-12 | 天津市中西医结合医院(天津市南开医院) | 检测g蛋白偶联受体18的试剂在制备败血症诊断及病程监测和预后判断试剂中表达的应用 |
| US20240108689A1 (en) * | 2021-01-22 | 2024-04-04 | The Brigham And Women's Hospital, Inc. | Modulation of a pathogenic phenotype in th1 cells |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6555339B1 (en) | 1997-04-14 | 2003-04-29 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human protein-coupled receptors |
| CA2481507A1 (en) * | 2002-04-16 | 2003-10-30 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| US20040018522A1 (en) * | 2002-05-09 | 2004-01-29 | Brigham And Women's Hospital, Inc. | Identification of dysregulated genes in patients with multiple sclerosis |
-
2005
- 2005-05-03 GB GBGB0508988.3A patent/GB0508988D0/en not_active Ceased
-
2006
- 2006-05-02 WO PCT/EP2006/004096 patent/WO2006117194A2/en not_active Ceased
- 2006-05-02 EP EP06724680A patent/EP1880219B1/de not_active Expired - Lifetime
- 2006-05-02 JP JP2008509370A patent/JP2008540361A/ja active Pending
- 2006-05-02 ES ES06724680T patent/ES2370035T3/es not_active Expired - Lifetime
- 2006-05-02 US US11/913,498 patent/US20090208997A1/en not_active Abandoned
- 2006-05-02 AT AT06724680T patent/ATE517346T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006117194A3 (en) | 2007-01-18 |
| EP1880219A2 (de) | 2008-01-23 |
| ES2370035T3 (es) | 2011-12-12 |
| JP2008540361A (ja) | 2008-11-20 |
| GB0508988D0 (en) | 2005-06-08 |
| EP1880219B1 (de) | 2011-07-20 |
| US20090208997A1 (en) | 2009-08-20 |
| WO2006117194A2 (en) | 2006-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |