ATE517623T1 - Verwendung von methylphenidat-derivaten - Google Patents
Verwendung von methylphenidat-derivatenInfo
- Publication number
- ATE517623T1 ATE517623T1 AT06719144T AT06719144T ATE517623T1 AT E517623 T1 ATE517623 T1 AT E517623T1 AT 06719144 T AT06719144 T AT 06719144T AT 06719144 T AT06719144 T AT 06719144T AT E517623 T1 ATE517623 T1 AT E517623T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- methylphenidate derivatives
- methylphenidate
- derivatives
- prodrugs
- Prior art date
Links
- DUGOZIWVEXMGBE-UHFFFAOYSA-N Methylphenidate Chemical class C=1C=CC=CC=1C(C(=O)OC)C1CCCCN1 DUGOZIWVEXMGBE-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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-
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
- Virology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64577805P | 2005-01-20 | 2005-01-20 | |
| PCT/US2006/002181 WO2006078984A2 (en) | 2005-01-20 | 2006-01-20 | Uses of methylphenidate derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE517623T1 true ATE517623T1 (de) | 2011-08-15 |
Family
ID=36692960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06719144T ATE517623T1 (de) | 2005-01-20 | 2006-01-20 | Verwendung von methylphenidat-derivaten |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20060183773A1 (de) |
| EP (1) | EP1845780B1 (de) |
| JP (3) | JP5274844B2 (de) |
| CN (1) | CN101123965B (de) |
| AT (1) | ATE517623T1 (de) |
| ES (1) | ES2372004T3 (de) |
| HR (1) | HRP20110779T1 (de) |
| PL (1) | PL1845780T3 (de) |
| SI (1) | SI1845780T1 (de) |
| WO (1) | WO2006078984A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2595400C (en) * | 2005-01-20 | 2017-01-17 | Institute For Molecular Medicine, Inc. | Methylphenidate derivatives and their use in the treatment of angiogenic diseases and conditions |
| JP5856843B2 (ja) * | 2008-05-27 | 2016-02-10 | アンピオ ファーマシューティカルズ，インコーポレイテッド | ジケトピペラジンを用いた医薬組成物 |
| CN102134208B (zh) * | 2010-01-27 | 2014-05-14 | 爱斯特（成都）医药技术有限公司 | [r,r]-哌甲酯中间体及其类似物以及它们的合成与应用 |
| US10085414B2 (en) * | 2011-05-19 | 2018-10-02 | Gilrose Pharmaceuticals, Llc | Pre-frontal cortex processing disorder speech, gait and limb impairments treatment |
| WO2016110998A1 (ja) * | 2015-01-09 | 2016-07-14 | 三菱電機株式会社 | 室外機及び空気調和装置 |
| SG10201408115SA (en) * | 2014-12-05 | 2016-07-28 | Chakra Biotech Pte Ltd | Use of tetrahydropyridines in the treatment of sodium channel related disease and disorders |
| JP7199656B2 (ja) * | 2018-12-07 | 2023-01-06 | 日本たばこ産業株式会社 | 注意欠如・多動症又は注意欠如・多動性障害の評価方法及び評価を補助するための方法、並びに注意欠如・多動症又は注意欠如・多動性障害を評価するためのデータ取得方法 |
| IT202000019303A1 (it) * | 2020-08-05 | 2022-02-05 | Univ Degli Studi Di Brescia | Analoghi strutturali del metilfenidato come agenti disease-modifying della malattia di parkinson |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2507631A (en) * | 1944-01-19 | 1950-05-16 | Ciba Pharm Prod Inc | Pyridine and piperidine compounds and process of making same |
| US2957880A (en) * | 1953-12-23 | 1960-10-25 | Ciba Pharm Prod Inc | Process for the conversion of stereoisomers |
| US5407926A (en) * | 1987-12-29 | 1995-04-18 | Alcon Laboratories, Inc. | Ophthalmic composition |
| EP0754046A1 (de) * | 1994-04-04 | 1997-01-22 | FREEMAN, William R. | Verwendung der phosphonylmethoxyalkyl-nukleoside zur behandlung des erhöhten innenaugendrucks |
| US5658955A (en) * | 1994-11-01 | 1997-08-19 | Hitzig; Pietr | Combined use of dopamine and serotonin agonists in the treatment of immune disorders |
| KR19990028983A (ko) * | 1995-07-14 | 1999-04-15 | 피터 제이. 코젠스 | 디-트레오-메틸페니데이트 및 다른 약품으로 이루어진 조성물 |
| US6486177B2 (en) * | 1995-12-04 | 2002-11-26 | Celgene Corporation | Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate |
| US5908850A (en) * | 1995-12-04 | 1999-06-01 | Celgene Corporation | Method of treating attention deficit disorders with d-threo methylphenidate |
| US5922736A (en) * | 1995-12-04 | 1999-07-13 | Celegene Corporation | Chronic, bolus administration of D-threo methylphenidate |
| US5859249A (en) * | 1997-02-19 | 1999-01-12 | Takasago International Corporation | 2-phenyl-2-(2'-piperidinylidene)acetate derivative, process for manufacturing the same, and process for manufacturing optically active 2-phenyl-2-(2'-piperidinyl)acetate derivative by asymmetrically hydrogenating the same |
| US6210705B1 (en) * | 1997-12-15 | 2001-04-03 | Noven Pharmaceuticals, Nc. | Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
| US6395752B1 (en) * | 1999-03-04 | 2002-05-28 | Pharmaquest Limited | Method of treating depression using 1-threo-methylphenidate |
| US6127385A (en) * | 1999-03-04 | 2000-10-03 | Pharmaquest Limited | Method of treating depression using l-threo-methylphenidate |
| US6025502A (en) * | 1999-03-19 | 2000-02-15 | The Trustees Of The University Of Pennsylvania | Enantopselective synthesis of methyl phenidate |
| DE19927080A1 (de) * | 1999-06-15 | 2000-12-21 | Zahnradfabrik Friedrichshafen | Zahnradlagerung in Getrieben |
| US20020132793A1 (en) * | 2000-08-28 | 2002-09-19 | Mel Epstein | Use of methylphenidate compounds to enhance memory |
| US20050101582A1 (en) * | 2003-11-12 | 2005-05-12 | Allergan, Inc. | Compositions and methods for treating a posterior segment of an eye |
| US20050192290A1 (en) * | 2004-01-13 | 2005-09-01 | Isaac Melamed | Treatment of behavioral disorders |
| CA2595400C (en) * | 2005-01-20 | 2017-01-17 | Institute For Molecular Medicine, Inc. | Methylphenidate derivatives and their use in the treatment of angiogenic diseases and conditions |
-
2006
- 2006-01-20 JP JP2007552311A patent/JP5274844B2/ja not_active Expired - Fee Related
- 2006-01-20 CN CN2006800055421A patent/CN101123965B/zh not_active Expired - Fee Related
- 2006-01-20 US US11/336,436 patent/US20060183773A1/en not_active Abandoned
- 2006-01-20 WO PCT/US2006/002181 patent/WO2006078984A2/en not_active Ceased
- 2006-01-20 AT AT06719144T patent/ATE517623T1/de not_active IP Right Cessation
- 2006-01-20 ES ES06719144T patent/ES2372004T3/es not_active Expired - Lifetime
- 2006-01-20 PL PL06719144T patent/PL1845780T3/pl unknown
- 2006-01-20 EP EP06719144A patent/EP1845780B1/de not_active Expired - Lifetime
- 2006-01-20 HR HR20110779T patent/HRP20110779T1/hr unknown
- 2006-01-20 SI SI200631125T patent/SI1845780T1/sl unknown
-
2013
- 2013-03-11 JP JP2013048099A patent/JP5681226B2/ja not_active Expired - Fee Related
-
2014
- 2014-10-08 JP JP2014207423A patent/JP2015003931A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1845780A2 (de) | 2007-10-24 |
| SI1845780T1 (sl) | 2012-01-31 |
| WO2006078984A2 (en) | 2006-07-27 |
| JP5681226B2 (ja) | 2015-03-04 |
| WO2006078984A3 (en) | 2006-11-09 |
| JP2008528505A (ja) | 2008-07-31 |
| EP1845780A4 (de) | 2009-04-01 |
| JP2013199478A (ja) | 2013-10-03 |
| PL1845780T3 (pl) | 2011-12-30 |
| ES2372004T3 (es) | 2012-01-12 |
| CN101123965A (zh) | 2008-02-13 |
| JP5274844B2 (ja) | 2013-08-28 |
| EP1845780B1 (de) | 2011-07-27 |
| JP2015003931A (ja) | 2015-01-08 |
| HRP20110779T1 (hr) | 2011-12-31 |
| CN101123965B (zh) | 2012-08-22 |
| US20060183773A1 (en) | 2006-08-17 |
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