ATE518526T1 - Neue pharmazeutische zusammensetzung mit candesartan-cilexetil als lipophile kristalline substanz - Google Patents

Neue pharmazeutische zusammensetzung mit candesartan-cilexetil als lipophile kristalline substanz

Info

Publication number: ATE518526T1
Authority: AT; Austria
Prior art keywords: cilexetil; candesartan; pharmaceutical composition; crystalline substance; new pharmaceutical
Prior art date: 2005-01-26

Application number

AT06700941T

Other languages

English (en)

Inventor

Zdenka Jerala-Strukelj

Igor Legen

Original Assignee

Lek Pharmaceuticals

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-01-26

Filing date

2006-01-24

Publication date

2011-08-15

2006-01-24 Application filed by Lek Pharmaceuticals filed Critical Lek Pharmaceuticals

2011-08-15 Application granted granted Critical

2011-08-15 Publication of ATE518526T1 publication Critical patent/ATE518526T1/de

Links

GHOSNRCGJFBJIB-UHFFFAOYSA-N Candesartan cilexetil Chemical compound C=12N(CC=3C=CC(=CC=3)C=3C(=CC=CC=3)C3=NNN=N3)C(OCC)=NC2=CC=CC=1C(=O)OC(C)OC(=O)OC1CCCCC1 GHOSNRCGJFBJIB-UHFFFAOYSA-N 0.000 title abstract 2
229960004349 candesartan cilexetil Drugs 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
239000000126 substance Substances 0.000 title 1
239000004480 active ingredient Substances 0.000 abstract 1
229940113118 carrageenan Drugs 0.000 abstract 1
235000010418 carrageenan Nutrition 0.000 abstract 1
229920001525 carrageenan Polymers 0.000 abstract 1
239000000679 carrageenan Substances 0.000 abstract 1
230000015556 catabolic process Effects 0.000 abstract 1
238000006731 degradation reaction Methods 0.000 abstract 1
UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Plural Heterocyclic Compounds (AREA)

AT06700941T 2005-01-26 2006-01-24 Neue pharmazeutische zusammensetzung mit candesartan-cilexetil als lipophile kristalline substanz ATE518526T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SI200500021		2005-01-26
PCT/EP2006/000587 WO2006079496A1 (en)	2005-01-26	2006-01-24	New pharmaceutical composition containing candesartan cilexetil as lipophilic crystalline substance

Publications (1)

Publication Number	Publication Date
ATE518526T1 true ATE518526T1 (de)	2011-08-15

Family

ID=36035685

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06700941T ATE518526T1 (de)	2005-01-26	2006-01-24	Neue pharmazeutische zusammensetzung mit candesartan-cilexetil als lipophile kristalline substanz

Country Status (9)

Country	Link
US (1)	US20080118564A1 (de)
EP (1)	EP1843754B1 (de)
JP (1)	JP2008528456A (de)
AT (1)	ATE518526T1 (de)
DK (1)	DK1843754T3 (de)
ES (1)	ES2371145T3 (de)
PL (1)	PL1843754T3 (de)
SI (1)	SI1843754T1 (de)
WO (1)	WO2006079496A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI407978B (zh) *	2005-06-27	2013-09-11	Sankyo Co	濕粒狀藥物之製備方法
TWI494134B (zh) *	2006-06-20	2015-08-01	Siegfried Generics Int Ag	含有坎地沙坦酯的組成物、錠劑和顆粒及該錠劑的製造方法
WO2008045006A1 (en) *	2006-10-11	2008-04-17	Fako Ilaclari A. S.	Formulations of candesartan
ES2301401B1 (es) *	2006-11-28	2009-06-08	Laboratorios Liconsa S.A.	Composicion farmaceutica solida estabilizada de candesartan cilexetilo.
DK2165702T3 (da)	2008-09-17	2012-03-05	Helm Ag	Stabile og let opløselige sammensætninger af candesartancilexetil fremstillet ved vådgranulering
CN102415998A (zh) *	2010-09-28	2012-04-18	扬子江药业集团北京海燕药业有限公司	盐酸马尼地平固体分散体及其制备方法
JP2013224265A (ja) *	2012-04-19	2013-10-31	Asahi Kasei Chemicals Corp	打圧感受性薬物を含有する錠剤
EP2928468A4 (de)	2012-12-05	2016-07-27	Sawai Seiyaku Kk	Candesartancilexetilhaltiges präparat
CN103006598B (zh) *	2012-12-31	2015-12-02	广州白云山天心制药股份有限公司	含氯化钠药物载体的降血压片剂
CA2910112C (en)	2013-04-25	2021-02-16	Kyorin Pharmaceutical Co., Ltd.	Solid pharmaceutical composition
JP5844929B1 (ja) *	2015-04-03	2016-01-20	共和薬品工業株式会社	カンデサルタンシレキセチル及びヒドロクロロチアジドを含む錠剤
EP3219309A1 (de) *	2016-03-17	2017-09-20	K.H.S. Pharma Holding GmbH	Pharmazeutische zusammensetzung mit fixdosierungskombination von amlodipin, candesartan cilexetil und hydrochlorothiazid zur behandlung von bluthochdruck
CN110876726A (zh) *	2019-11-20	2020-03-13	白喜平	一种坎地沙坦酯制剂及其制备方法
EP4238578A4 (de) *	2020-10-30	2024-09-11	Eisai R&D Management Co., Ltd.	Pharmazeutische zusammensetzung
JP7814963B2 (ja) *	2022-02-07	2026-02-17	株式会社ファンケル	錠剤、錠剤の崩壊性を改善する方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5196444A (en) *	1990-04-27	1993-03-23	Takeda Chemical Industries, Ltd.	1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
TW284688B (de) *	1991-11-20	1996-09-01	Takeda Pharm Industry Co Ltd
EP0914158B2 (de) *	1996-04-05	2006-01-25	Takeda Chemical Industries, Ltd.	Pharmazeutische kombination enthaltend einen wirkstoff mit angiotensin-ii antagonistischer aktivität und einen wirkstoff der die insulin-sensitivität erhöht
US6210710B1 (en) *	1997-04-28	2001-04-03	Hercules Incorporated	Sustained release polymer blend for pharmaceutical applications
TW585786B (en) *	1998-07-28	2004-05-01	Takeda Chemical Industries Ltd	Lansoprazole-containing rapidly disintegrable solid pharmaceutical composition
DK1216038T3 (da) *	1999-08-30	2005-12-27	Sanofi Aventis Deutschland	Anvendelse af inhibitorer af reninangiotensinsystemet ved forebyggelsen af cardiovaskulære hændelser
DE10029201A1 (de) *	2000-06-19	2001-12-20	Basf Ag	Verfahren zur Herstellung fester oraler Darreichungsformen mit retardierender Wirkstoffreisetzung
WO2002030400A1 (fr) *	2000-10-06	2002-04-18	Takeda Chemical Industries, Ltd.	Preparations solides
ES2366430T3 (es) *	2001-06-20	2011-10-20	Takeda Pharmaceutical Company Limited	Método para fabricar comprimidos.
AUPS236902A0 (en) *	2002-05-16	2002-06-13	Northern Sydney Area Health Service	Composition and method for treating hypertension
US20040202730A1 (en) *	2003-04-08	2004-10-14	Robert Gow	Rosmarinic acid composition

2006
- 2006-01-24 WO PCT/EP2006/000587 patent/WO2006079496A1/en not_active Ceased
- 2006-01-24 AT AT06700941T patent/ATE518526T1/de active
- 2006-01-24 DK DK06700941.5T patent/DK1843754T3/da active
- 2006-01-24 EP EP06700941A patent/EP1843754B1/de not_active Expired - Lifetime
- 2006-01-24 JP JP2007551631A patent/JP2008528456A/ja active Pending
- 2006-01-24 US US11/795,920 patent/US20080118564A1/en not_active Abandoned
- 2006-01-24 SI SI200631159T patent/SI1843754T1/sl unknown
- 2006-01-24 ES ES06700941T patent/ES2371145T3/es not_active Expired - Lifetime
- 2006-01-24 PL PL06700941T patent/PL1843754T3/pl unknown

Also Published As

Publication number	Publication date
WO2006079496A1 (en)	2006-08-03
US20080118564A1 (en)	2008-05-22
ES2371145T3 (es)	2011-12-27
JP2008528456A (ja)	2008-07-31
DK1843754T3 (da)	2011-11-21
EP1843754B1 (de)	2011-08-03
SI1843754T1 (sl)	2011-12-30
EP1843754A1 (de)	2007-10-17
PL1843754T3 (pl)	2011-12-30

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