ATE518540T1 - Beta-lactam verbindung enthaltende neurotherapeutische zusammensetzung - Google Patents
Beta-lactam verbindung enthaltende neurotherapeutische zusammensetzungInfo
- Publication number
- ATE518540T1 ATE518540T1 AT00959244T AT00959244T ATE518540T1 AT E518540 T1 ATE518540 T1 AT E518540T1 AT 00959244 T AT00959244 T AT 00959244T AT 00959244 T AT00959244 T AT 00959244T AT E518540 T1 ATE518540 T1 AT E518540T1
- Authority
- AT
- Austria
- Prior art keywords
- lactam compound
- composition containing
- containing beta
- neurotherapeutic
- treatment
- Prior art date
Links
- -1 BETA-LACTAM COMPOUND Chemical class 0.000 title 1
- 150000002148 esters Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 1
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 abstract 1
- JWCSIUVGFCSJCK-CAVRMKNVSA-N Disodium Moxalactam Chemical compound N([C@]1(OC)C(N2C(=C(CSC=3N(N=NN=3)C)CO[C@@H]21)C(O)=O)=O)C(=O)C(C(O)=O)C1=CC=C(O)C=C1 JWCSIUVGFCSJCK-CAVRMKNVSA-N 0.000 abstract 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000004403 Prostatic Hyperplasia Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 abstract 1
- 229960003324 clavulanic acid Drugs 0.000 abstract 1
- 229960000433 latamoxef Drugs 0.000 abstract 1
- 208000012201 sexual and gender identity disease Diseases 0.000 abstract 1
- 208000015891 sexual disease Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
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- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
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- A61K31/425—Thiazoles
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- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
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- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
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- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Physical Education & Sports Medicine (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14911599P | 1999-08-16 | 1999-08-16 | |
| US17245299P | 1999-12-17 | 1999-12-17 | |
| US17657000P | 2000-01-18 | 2000-01-18 | |
| US19453400P | 2000-04-04 | 2000-04-04 | |
| PCT/US2000/022450 WO2001012184A1 (en) | 1999-08-16 | 2000-08-16 | Neurotherapeutic composition and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE518540T1 true ATE518540T1 (de) | 2011-08-15 |
Family
ID=27495857
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00959244T ATE518540T1 (de) | 1999-08-16 | 2000-08-16 | Beta-lactam verbindung enthaltende neurotherapeutische zusammensetzung |
| AT00955580T ATE319447T1 (de) | 1999-08-16 | 2000-08-16 | Pharmazeutische zubereitungen die clavulansäure oder derivate enthalten zur behandlund von neurologischen störungen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00955580T ATE319447T1 (de) | 1999-08-16 | 2000-08-16 | Pharmazeutische zubereitungen die clavulansäure oder derivate enthalten zur behandlund von neurologischen störungen |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US6627625B1 (de) |
| EP (3) | EP1206261B1 (de) |
| JP (2) | JP5049437B2 (de) |
| CN (1) | CN1382047A (de) |
| AT (2) | ATE518540T1 (de) |
| AU (2) | AU781218B2 (de) |
| BR (1) | BR0013366A (de) |
| CA (3) | CA2383522C (de) |
| DE (1) | DE60026538T2 (de) |
| DK (1) | DK1206261T3 (de) |
| ES (1) | ES2258980T3 (de) |
| MX (1) | MXPA02001667A (de) |
| NZ (1) | NZ517663A (de) |
| WO (2) | WO2001012184A1 (de) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2383522C (en) * | 1999-08-16 | 2011-12-06 | Revaax Pharmaceuticals, Llc | Neurotherapeutic composition and method |
| US6489319B2 (en) * | 1999-08-16 | 2002-12-03 | Revaax Pharmaceuticals, Llc | Neurotherapeutic use of carboxypeptidase inhibitors |
| US6426342B2 (en) * | 1999-08-16 | 2002-07-30 | Revaax Pharmaceuticals, Llc | Use of β-lactamase inhibitors as neuroprotectants |
| AU2001291499B2 (en) * | 2000-09-29 | 2007-02-08 | Nucor Corporation | A method of producing steel |
| US20030013635A1 (en) * | 2001-04-11 | 2003-01-16 | Meyerhoff James L. | Method for the treatment of depression by inhibition of NAALADase |
| WO2002092101A1 (en) | 2001-05-15 | 2002-11-21 | Psychogenics Inc. | Systems and methods for monitoring behavior informatics |
| US7166626B2 (en) * | 2001-06-18 | 2007-01-23 | Revaax Pharmaceuticals, Llc | Therapeutic treatment for sexual dysfunction |
| AU2002342045C1 (en) * | 2001-10-12 | 2009-07-30 | Azevan Pharmaceuticals, Inc. | Beta-lactamyl vasopressin Vla antagonists |
| US6602911B2 (en) | 2001-11-05 | 2003-08-05 | Cypress Bioscience, Inc. | Methods of treating fibromyalgia |
| AU2003202942A1 (en) * | 2002-01-17 | 2003-09-02 | R.E.D. Laboratories, N.V./S.A. | Methods of treatment of chronic immune disease |
| PT1485078E (pt) * | 2002-03-15 | 2013-01-14 | Cypress Bioscience Inc | Milnacipran para o tratamento do síndrome do intestino irritável |
| JP2006504795A (ja) * | 2002-10-03 | 2006-02-09 | サイプレス バイオサイエンス, インコーポレイテッド | 神経学的障害を処置するための抗うつ剤の投薬量の段階的な漸増ならびに毎日の分割した投薬 |
| EP1567674A4 (de) * | 2002-11-22 | 2007-09-26 | Univ Johns Hopkins | Ziel für die therapie einer kognitivenbeeinträchtigung |
| DE602004021574D1 (de) * | 2003-02-26 | 2009-07-30 | Univ Johns Hopkins | Modulatorische verbindungen und verfahren für glutamattransport |
| KR20070026295A (ko) * | 2003-08-25 | 2007-03-08 | 레박스 파마슈티칼즈, 엘엘씨 | 경구 신경치료 세파졸린 조성물 |
| AU2004285473A1 (en) * | 2003-10-21 | 2005-05-12 | Johns Hopkins University | Neuroprotection with beta-lactam compounds |
| AU2006227199A1 (en) | 2005-03-22 | 2006-09-28 | Azevan Pharmaceuticals, Inc. | Beta-lactamylalkanoic acids for treating premenstrual disorders |
| EP2201963B1 (de) | 2005-04-05 | 2016-01-27 | Yale University | Glutamatmodulationsmittel bei der Behandlung mentaler Störungen |
| DK1910346T3 (da) | 2005-07-19 | 2019-05-27 | Azevan Pharmaceuticals Inc | Beta-lactamyl fenylalanin, cystein og serin vasopressin antagonist |
| US7994220B2 (en) * | 2005-09-28 | 2011-08-09 | Cypress Bioscience, Inc. | Milnacipran for the long-term treatment of fibromyalgia syndrome |
| WO2008034032A2 (en) * | 2006-09-14 | 2008-03-20 | Azevan Pharmaceuticals, Inc. | Beta-lactam cannabinoid receptor modulators |
| CA2702257C (en) | 2007-10-09 | 2016-07-12 | Sopharmia, Inc. | Broad spectrum beta-lactamase inhibitors |
| EP2214680A4 (de) * | 2007-10-26 | 2010-12-29 | Rexahn Pharmaceuticals Inc | Pharmazeutische formulierung von clavulansäure |
| US8101600B2 (en) * | 2008-12-23 | 2012-01-24 | Brookhaven Science Associates, Llc | Method of treating depression |
| WO2010118361A1 (en) * | 2009-04-09 | 2010-10-14 | Sopharmia, Inc. | Beta lactamase inhibitors |
| CA2758029A1 (en) * | 2009-04-29 | 2011-11-04 | Rexahn Pharmaceuticals, Inc. | Clavulanate formulation for neuroprotection and treatment of neurodegenerative disorders |
| EP2587919B1 (de) | 2010-07-01 | 2017-12-13 | Azevan Pharmaceuticals, Inc. | Verfahren zur behandlung posttraumatischer belastungsstörungen |
| WO2013006808A2 (en) * | 2011-07-06 | 2013-01-10 | Rexahn Pharmaceuticals, Inc. | Clavulanic acid for treatment of restless legs syndrome |
| CN103648496B (zh) * | 2011-07-26 | 2016-05-25 | 沃克哈特有限公司 | 包含β-内酰胺抗生素、舒巴坦和β-内酰胺酶抑制剂的药物组合物 |
| MX338610B (es) | 2011-07-26 | 2016-04-25 | Wockhardt Ltd | Composiciones farmaceuticas que comprenden sulbactam e inhibidor de beta-lactamasa. |
| HK1199402A1 (en) | 2011-09-21 | 2015-07-03 | 干细胞医药有限公司 | Beta-lactam compounds for enhancing t cell -mediated immune responses |
| HK1201466A1 (en) | 2011-09-21 | 2015-09-04 | 干细胞医药有限公司 | Beta-lactam compounds for treating diabetes |
| US9770423B2 (en) | 2012-07-22 | 2017-09-26 | Indiana University Research And Technology Corporation | Modulation sAPP, sAAPα and BDNF levels in individuals diagnosed with FXS and ASD |
| US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
| JP6403289B2 (ja) | 2013-03-12 | 2018-10-10 | グラディウス ファーマシューティカルズ コーポレーションGladius Pharmaceuticals Corporation | 誘導体化3−スチリル−セファロスポリン |
| US20140274993A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Ceftolozane-tazobactam pharmaceutical compositions |
| US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
| NZ700372A (en) | 2013-03-15 | 2016-01-29 | Merck Sharp & Dohme | Ceftolozane antibiotic compositions |
| EP3043797B1 (de) | 2013-09-09 | 2020-04-08 | Merck Sharp & Dohme Corp. | Behandlung von infektionen mit ceftolozan/tazobactam bei personen mit beeinträchtigter nierenfunktion |
| US8906898B1 (en) | 2013-09-27 | 2014-12-09 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
| WO2015057736A1 (en) | 2013-10-14 | 2015-04-23 | Indiana University Research And Technology Corporation | Use of acamprosate to modulate erk 1-2 activation in animal models for fxs and asd and individuals diagnosed with fxs and asd |
| SG11201608064WA (en) | 2014-03-28 | 2016-10-28 | Azevan Pharmaceuticals Inc | Compositions and methods for treating neurodegenerative diseases |
| WO2017218697A1 (en) * | 2016-06-17 | 2017-12-21 | The Trustees Columbia University In The City Of New York | Identification of compounds that target the rna-binding protein tia-1 an important regulator of stress vulnerability in both mice and humans |
| KR102790657B1 (ko) | 2017-09-15 | 2025-04-02 | 아제반 파마슈티칼스, 인코퍼레이티드 | 뇌 손상을 치료하기 위한 조성물 및 방법 |
| CN108522431A (zh) * | 2018-04-03 | 2018-09-14 | 葛仟鸿 | 抗生素对果蝇记忆认知影响用测定方法 |
| ES2960952T3 (es) | 2018-08-09 | 2024-03-07 | Antabio Sas | Diazabiciclooctanonas como inhibidores de serina beta-lactamasas |
| US11905286B2 (en) | 2018-08-09 | 2024-02-20 | Antabio Sas | Diazabicyclooctanones as inhibitors of serine beta-lactamases |
| WO2020263975A1 (en) * | 2019-06-24 | 2020-12-30 | Diverse Biotech, Inc. | Beta-lactam-cannabinoid conjugate molecules |
| CN112843034B (zh) * | 2019-11-26 | 2022-08-23 | 亚瑟瑞智科技管理顾问股份有限公司 | 包含克拉维酸与丙戊酸的组合物及其用途 |
| WO2022102801A1 (ko) * | 2020-11-10 | 2022-05-19 | 김현기 | 오배자 추출물 및 암피실린을 유효성분으로 포함하는 인지력 개선, 치매 및 과잉행동장애 예방 및 치료용 조성물 |
| CN114767690B (zh) * | 2022-06-22 | 2022-08-23 | 中国中医科学院中药研究所 | 头孢噻吩酸在制备抗抑郁药物中的应用 |
| CN117144006B (zh) * | 2023-08-18 | 2025-02-18 | 大连医科大学附属第二医院 | Lactb基因及其在诊断前列腺癌中的应用 |
Family Cites Families (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1508977A (en) * | 1974-04-20 | 1978-04-26 | Beecham Group Ltd | Beta-lactam antibiotic from streptomyces clavuligerus |
| US4110165A (en) * | 1974-04-20 | 1978-08-29 | Beecham Group Limited | Process for the production of clavulanic acid |
| CA1085392A (en) | 1976-03-25 | 1980-09-09 | Masayuki Narisada | Arylmalonamido-1-oxadethiacephalosporins |
| US4127118B1 (en) * | 1977-03-16 | 1995-12-19 | Alvaro Latorre | Method of effecting and enhancing an erection |
| US4234579A (en) * | 1977-06-07 | 1980-11-18 | Pfizer Inc. | Penicillanic acid 1,1-dioxides as β-lactamase inhibitors |
| JO984B1 (en) * | 1977-10-11 | 1979-12-01 | بيتشام غروب ليمتد | A dry pharmaceutical compound with a suitable dosage unit for oral administration |
| NZ189022A (en) * | 1977-12-08 | 1981-11-19 | Beecham Group Ltd | Pharmaceutically acceptable particles of clavulanates dispersed in a polymeric binder |
| US4273763A (en) | 1978-01-23 | 1981-06-16 | Efamol Limited | Pharmaceutical and dietary compositions |
| US4268503A (en) | 1978-09-14 | 1981-05-19 | Fujisawa Pharmaceutical Co., Ltd. | Antibacterial composition |
| US4302503A (en) * | 1978-05-17 | 1981-11-24 | Libbey-Owens-Ford Company | Architectural spandrel |
| US4349672A (en) * | 1979-11-29 | 1982-09-14 | Hoffmann-La Roche Inc. | Cephalosporin derivatives |
| NZ198241A (en) * | 1980-09-27 | 1983-12-16 | Beecham Group Ltd | Tablet containing amoxycillin and potassium clavulanate |
| US4594247A (en) * | 1981-12-21 | 1986-06-10 | Eli Lilly And Company | Synergistic antibacterial compositions and method of treatment of infections caused by multiple antibiotic-resistant organisms |
| US4880921A (en) | 1982-05-18 | 1989-11-14 | University Of Florida | Brain-specific drug delivery |
| US5525727A (en) | 1982-05-18 | 1996-06-11 | University Of Florida | Brain-specific drug delivery |
| US4540564A (en) | 1982-05-18 | 1985-09-10 | University Of Florida | Brain-specific drug delivery |
| US5187158A (en) | 1982-05-18 | 1993-02-16 | University Of Florida | Brain-specific drug delivery |
| US4824850A (en) | 1982-05-18 | 1989-04-25 | University Of Florida | Brain-specific drug delivery |
| US5008257A (en) | 1982-05-18 | 1991-04-16 | University Of Florida | Brain-specific drug delivery |
| US4900837A (en) | 1982-05-18 | 1990-02-13 | University Of Florida | Brain-specific drug delivery of steroid sex hormones cleaved from pyridinium carboxylates and dihydro-pyridine carboxylate precursors |
| JPS59104389A (ja) * | 1982-12-06 | 1984-06-16 | Shionogi & Co Ltd | オキサセファム誘導体 |
| JPS59225182A (ja) * | 1983-03-25 | 1984-12-18 | Yamanouchi Pharmaceut Co Ltd | 2−アゼチジノン−4−カルボン酸の誘導体 |
| US4628077A (en) | 1983-12-16 | 1986-12-09 | The Standard Oil Company | Preparation of polyamide with catalyst comprising transition metal attached to a ligand which contains electron withdrawing groups |
| US4771059A (en) | 1984-02-29 | 1988-09-13 | University Of Florida | Brain-specific analogues of centrally acting amines |
| US5082853A (en) | 1984-02-29 | 1992-01-21 | Bodor Nicholas S | Brain-specific analogues of centrally acting amines |
| US4933438A (en) | 1984-02-29 | 1990-06-12 | University Of Florida | Brain-specific analogues of centrally acting amines |
| JPS62106015A (ja) * | 1985-10-31 | 1987-05-16 | Sumitomo Pharmaceut Co Ltd | 抗痴呆薬 |
| US5256652A (en) * | 1987-11-12 | 1993-10-26 | Pharmedic Co. | Topical compositions and methods for treatment of male impotence |
| US5552543A (en) | 1988-12-14 | 1996-09-03 | Simon Fraser University | Six-membered hetero "N" compounds |
| US5672683A (en) | 1989-09-07 | 1997-09-30 | Alkermes, Inc. | Transferrin neuropharmaceutical agent fusion protein |
| US5177064A (en) | 1990-07-13 | 1993-01-05 | University Of Florida | Targeted drug delivery via phosphonate derivatives |
| US5681812A (en) | 1991-12-10 | 1997-10-28 | Rush Presbyterian-St. Luke's Medical Center | Methods and compositions for reducing multidrug resistance |
| GB9201639D0 (en) * | 1992-01-25 | 1992-03-11 | Smithkline Beecham Plc | Pharmaceutical formulations |
| GB9215908D0 (en) * | 1992-07-27 | 1992-09-09 | Wellcome Found | Water dispersible tablets |
| IL106998A0 (en) | 1992-09-17 | 1993-12-28 | Univ Florida | Brain-enhanced delivery of neuroactive peptides by sequential metabolism |
| IL108499A (en) | 1993-02-04 | 2000-02-29 | Lilly Co Eli | Mammalian influx peptide transporter |
| US5643909A (en) | 1993-04-19 | 1997-07-01 | Syntex (U.S.A.) Inc. | 10,11-Methanodibenzosuberane derivatives |
| CA2151714C (en) * | 1993-10-20 | 2005-10-11 | Shogo Ito | Mobile communications method |
| WO1995012601A1 (en) | 1993-11-06 | 1995-05-11 | Taiho Pharmaceutical Co., Ltd. | Crystalline penicillin derivative, and its production and use |
| US5567592A (en) * | 1994-02-02 | 1996-10-22 | Regents Of The University Of California | Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal |
| DE19509697A1 (de) | 1995-03-08 | 1996-09-12 | Schering Ag | Neue Borneole, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| US5827537A (en) * | 1995-05-04 | 1998-10-27 | Smithkline Beecham Corporation | Pharmaceutical thermal infusion process |
| GB9515411D0 (en) | 1995-07-27 | 1995-09-27 | Pharmacia Spa | N-(4-substituted-benzyl)-2-aminolactam derivatives |
| GB9518917D0 (en) | 1995-09-15 | 1995-11-15 | Smithkline Beecham Plc | Compounds |
| GB9525697D0 (en) * | 1995-12-15 | 1996-02-14 | Pharmacia Spa | Cephem derivatives |
| EP0939632B1 (de) | 1996-02-23 | 2005-10-05 | Eli Lilly And Company | Non-peptidische vasopressin via antagonisten |
| US5905076A (en) * | 1996-04-10 | 1999-05-18 | National Research Council Of Canada | 6-substituted amino-4-oxa-1-azabicyclo 3,2,0! heptan-7-one derivatives as cysteine protease inhibitors |
| US5795877A (en) * | 1996-12-31 | 1998-08-18 | Guilford Pharmaceuticals Inc. | Inhibitors of NAALADase enzyme activity |
| US5804602A (en) | 1996-06-17 | 1998-09-08 | Guilford Pharmaceuticals Inc. | Methods of cancer treatment using naaladase inhibitors |
| US5863536A (en) | 1996-12-31 | 1999-01-26 | Guilford Pharmaceuticals Inc. | Phosphoramidate derivatives |
| US5672592A (en) | 1996-06-17 | 1997-09-30 | Guilford Pharmaceuticals Inc. | Certain phosphonomethyl-pentanedioic acid derivatives thereof |
| US6017903A (en) | 1996-09-27 | 2000-01-25 | Guilford Pharmaceuticals Inc. | Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors |
| US5977090A (en) | 1996-09-27 | 1999-11-02 | Guilford Pharmaceuticals Inc. | Pharmaceutical compositions and methods of treating compulsive disorders using NAALADase inhibitors |
| US6384022B1 (en) * | 1996-06-17 | 2002-05-07 | Guilford Pharmaceuticals Inc. | Prodrugs of NAALAdase inhibitors |
| US5902817A (en) | 1997-04-09 | 1999-05-11 | Guilford Pharmaceuticals Inc. | Certain sulfoxide and sulfone derivatives |
| US6046180A (en) * | 1996-06-17 | 2000-04-04 | Guilford Pharmaceuticals Inc. | NAALADase inhibitors |
| US5824662A (en) | 1996-09-27 | 1998-10-20 | Guilford Pharmaceuticals Inc. | Treatment of global and focal ischemia using naaladase inhibitors |
| US6054444A (en) * | 1997-04-24 | 2000-04-25 | Guilford Pharmaceuticals Inc. | Phosphonic acid derivatives |
| US6071965A (en) * | 1996-06-17 | 2000-06-06 | Guilford Pharmaceuticals Inc. | Phosphinic alkanoic acid derivatives |
| ID18382A (id) * | 1996-09-27 | 1998-04-02 | Guilford Pharm Inc | Komposisi sediaan farmasi dan metoda pengobatan gangguan kompulsif dengan menggunakan inhibitor naaladase |
| US5962521A (en) * | 1997-04-04 | 1999-10-05 | Guilford Pharmaceuticals Inc. | Hydroxamic acid derivatives |
| CN1230889A (zh) * | 1996-09-27 | 1999-10-06 | 吉尔福特药业有限公司 | NAALADase组合物和治疗谷氨酸异常及在动物中产生神经元活性的方法 |
| US6232305B1 (en) | 1997-01-23 | 2001-05-15 | Naeja Pharmaceutical Inc. | Substituted amino bicyclic-β-lactam penam and cepham derivatives as cysteine protease inhibitors |
| EP0994707A4 (de) * | 1997-05-27 | 2001-11-14 | Guilford Pharm Inc | Inhibitoren der naaladase-enzym-aktivität |
| US6075014A (en) * | 1997-06-13 | 2000-06-13 | Northwestern University | Inhibitors of β-lactamases and uses therefor |
| EP1015623A1 (de) | 1997-08-22 | 2000-07-05 | Purdue Research Foundation | Auffinden von medikamenten unter verwendung von mehrfachen membranen mit mimetischen affinitäten |
| AU2114199A (en) | 1998-01-13 | 1999-08-02 | Trustees Of The University Of Pennsylvania, The | Novel dopamine re-uptake inhibitors and methods of synthesizing and using the same |
| US6015809A (en) | 1998-08-17 | 2000-01-18 | American Home Products Corporation | Photocyclized rapamycin |
| US6177421B1 (en) * | 1999-05-04 | 2001-01-23 | Fuisz International Ltd. | Amoxicillin and clavulanate composition |
| IE990159A1 (en) * | 1999-02-26 | 2000-09-20 | Fuisz Internat Ltd | Storage Stable Amoxycillin and Clavulanate Suspension Composition. |
| JP2003514765A (ja) | 1999-02-28 | 2003-04-22 | ワシントン ユニバーシティー | 新規形質導入分子およびその使用方法 |
| KR100686988B1 (ko) * | 1999-07-06 | 2007-02-27 | 메틸진, 인크. | β-락타마제의 술폰아미도메틸 포스포네이트 저해제 |
| US6489319B2 (en) | 1999-08-16 | 2002-12-03 | Revaax Pharmaceuticals, Llc | Neurotherapeutic use of carboxypeptidase inhibitors |
| US6426342B2 (en) | 1999-08-16 | 2002-07-30 | Revaax Pharmaceuticals, Llc | Use of β-lactamase inhibitors as neuroprotectants |
| CA2383522C (en) * | 1999-08-16 | 2011-12-06 | Revaax Pharmaceuticals, Llc | Neurotherapeutic composition and method |
| US20020013270A1 (en) * | 2000-06-05 | 2002-01-31 | Bolte Ellen R. | Method for treating a mental disorder |
| FR2811287B1 (fr) * | 2000-07-04 | 2002-10-04 | Look Cycle Int | Pedale de cycle a positionnement reglable perfectionne |
| WO2002064147A1 (en) | 2001-02-13 | 2002-08-22 | Revaax Pharmaceuticals, Llc | Antibiotic compositon and method |
| US7166626B2 (en) * | 2001-06-18 | 2007-01-23 | Revaax Pharmaceuticals, Llc | Therapeutic treatment for sexual dysfunction |
| SI21402A (sl) * | 2003-02-12 | 2004-08-31 | LEK farmacevtska dru�ba d.d. | Obloženi delci in farmacevtske oblike |
| KR20070026295A (ko) | 2003-08-25 | 2007-03-08 | 레박스 파마슈티칼즈, 엘엘씨 | 경구 신경치료 세파졸린 조성물 |
| ES2320360T3 (es) * | 2004-08-13 | 2009-05-21 | Schering-Plough Ltd. | Formulacion farmaceutica que comprende un antibiotico, un triazol y un corticosteroide. |
| DE102006007830A1 (de) * | 2006-02-17 | 2007-08-30 | Grünenthal GmbH | Lagerstabile orale Darreichungsform von Amoxicillin und Clavulansäure |
| US20080014257A1 (en) * | 2006-07-14 | 2008-01-17 | Par Pharmaceutical, Inc. | Oral dosage forms |
| CA2758029A1 (en) * | 2009-04-29 | 2011-11-04 | Rexahn Pharmaceuticals, Inc. | Clavulanate formulation for neuroprotection and treatment of neurodegenerative disorders |
-
2000
- 2000-08-16 CA CA2383522A patent/CA2383522C/en not_active Expired - Fee Related
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- 2000-08-16 DK DK00955580T patent/DK1206261T3/da active
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- 2000-08-16 MX MXPA02001667A patent/MXPA02001667A/es active IP Right Grant
- 2000-08-16 CA CA2746824A patent/CA2746824A1/en not_active Abandoned
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- 2000-08-16 EP EP10181885A patent/EP2305251A3/de not_active Withdrawn
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- 2000-08-16 US US09/640,362 patent/US6610681B1/en not_active Expired - Lifetime
- 2000-08-16 AT AT00959244T patent/ATE518540T1/de not_active IP Right Cessation
- 2000-08-16 WO PCT/US2000/022450 patent/WO2001012184A1/en not_active Ceased
- 2000-08-16 CN CN00814380A patent/CN1382047A/zh active Pending
- 2000-08-16 CA CA002380820A patent/CA2380820A1/en not_active Abandoned
- 2000-08-16 AT AT00955580T patent/ATE319447T1/de not_active IP Right Cessation
- 2000-08-16 AU AU70598/00A patent/AU7059800A/en not_active Abandoned
- 2000-08-16 EP EP00959244A patent/EP1212055B1/de not_active Expired - Lifetime
- 2000-08-16 BR BR0013366-3A patent/BR0013366A/pt not_active Application Discontinuation
- 2000-08-16 WO PCT/US2000/022434 patent/WO2001012171A2/en not_active Ceased
-
2003
- 2003-07-15 US US10/620,221 patent/US20040014739A1/en not_active Abandoned
- 2003-09-09 US US10/658,667 patent/US20040229857A1/en not_active Abandoned
-
2008
- 2008-01-23 US US12/018,542 patent/US7842683B2/en not_active Expired - Fee Related
-
2011
- 2011-05-16 JP JP2011109236A patent/JP2011201899A/ja active Pending
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