ATE519756T1 - Prophylaktikum bzw. therapeutikum für altersbedingte makuladegeneration - Google Patents
Prophylaktikum bzw. therapeutikum für altersbedingte makuladegenerationInfo
- Publication number
- ATE519756T1 ATE519756T1 AT08764549T AT08764549T ATE519756T1 AT E519756 T1 ATE519756 T1 AT E519756T1 AT 08764549 T AT08764549 T AT 08764549T AT 08764549 T AT08764549 T AT 08764549T AT E519756 T1 ATE519756 T1 AT E519756T1
- Authority
- AT
- Austria
- Prior art keywords
- prophylactic
- age
- macular degeneration
- related macular
- therapeutic
- Prior art date
Links
- 206010064930 age-related macular degeneration Diseases 0.000 title abstract 2
- 208000002780 macular degeneration Diseases 0.000 title abstract 2
- 230000000069 prophylactic effect Effects 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- DYEFUKCXAQOFHX-UHFFFAOYSA-N Ebselen Chemical compound [se]1C2=CC=CC=C2C(=O)N1C1=CC=CC=C1 DYEFUKCXAQOFHX-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 206010029113 Neovascularisation Diseases 0.000 abstract 1
- 230000005779 cell damage Effects 0.000 abstract 1
- 208000037887 cell injury Diseases 0.000 abstract 1
- 210000003161 choroid Anatomy 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 210000000844 retinal pigment epithelial cell Anatomy 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D293/00—Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms
- C07D293/10—Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D293/12—Selenazoles; Hydrogenated selenazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007138519 | 2007-05-25 | ||
| PCT/JP2008/059503 WO2008146721A1 (ja) | 2007-05-25 | 2008-05-23 | 加齢黄斑変性の予防又は治療剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE519756T1 true ATE519756T1 (de) | 2011-08-15 |
Family
ID=40074974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08764549T ATE519756T1 (de) | 2007-05-25 | 2008-05-23 | Prophylaktikum bzw. therapeutikum für altersbedingte makuladegeneration |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8309612B2 (de) |
| EP (1) | EP2163548B1 (de) |
| JP (1) | JP5314931B2 (de) |
| KR (1) | KR20100016140A (de) |
| CN (1) | CN101679328B (de) |
| AT (1) | ATE519756T1 (de) |
| CA (1) | CA2686560A1 (de) |
| ES (1) | ES2370751T3 (de) |
| RU (1) | RU2460526C2 (de) |
| WO (1) | WO2008146721A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1884234E (pt) | 2005-05-17 | 2012-07-26 | Santen Pharmaceutical Co Ltd | Agente profiláctico ou terapêutico para distúrbio corneano e conjuntival |
| WO2009107759A1 (ja) * | 2008-02-28 | 2009-09-03 | 参天製薬株式会社 | 視神経障害を伴う眼疾患の予防又は治療剤 |
| SI3708178T1 (sl) * | 2009-08-24 | 2024-01-31 | Stealth Biotherapeutics Inc. | Peptid za uporabo pri preprečevanju ali zdravljenju degeneracije makule |
| DK2493296T3 (en) | 2009-10-30 | 2019-04-15 | Retrotope Inc | REMOVAL OF OXIDATIVE STRESS STATES WITH PUFA DERIVATIVES |
| US20140018402A1 (en) * | 2011-03-30 | 2014-01-16 | Catholic University Industry Academic Cooperation Foundation | Pharmaceutical composition for preventing or treating macular degeneration |
| US10154983B2 (en) | 2011-04-26 | 2018-12-18 | Retrotope, Inc. | Neurodegenerative disorders and muscle diseases implicating PUFAs |
| US10058522B2 (en) | 2011-04-26 | 2018-08-28 | Retrotope, Inc. | Oxidative retinal diseases |
| KR102020579B1 (ko) | 2011-04-26 | 2019-09-10 | 레트로토프 인코포레이티드 | 에너지 프로세싱 손상 장애 및 미토콘드리아 결함 |
| WO2012148929A2 (en) | 2011-04-26 | 2012-11-01 | Retrotope, Inc. | Disorders implicating pufa oxidation |
| US10058542B1 (en) | 2014-09-12 | 2018-08-28 | Thioredoxin Systems Ab | Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith |
| WO2017091279A1 (en) | 2015-11-23 | 2017-06-01 | Retrotope, Inc. | Site-specific isotopic labeling of 1, 4-diene systems |
| GB201616158D0 (en) * | 2016-09-22 | 2016-11-09 | Provost Fellows Foundation Scholars & The Other Members Of Board Of The College Of The Holy & Unidv | Age-related macular degeneration |
| WO2020028923A2 (en) * | 2018-08-02 | 2020-02-06 | Curelab Oncology, Inc. | Compositions and methods relating to p62 for the treatment and prophylaxis of age-related macular degeneration |
| EP4107163A4 (de) | 2020-02-21 | 2024-06-19 | Retrotope, Inc. | Verfahren zur isotopenmodifizierung von mehrfach ungesättigten fettsäuren und deren derivaten |
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
| US11491130B2 (en) | 2021-02-05 | 2022-11-08 | Retrotope, Inc. | Methods of treating amyotrophic lateral sclerosis |
| WO2026073143A1 (en) * | 2024-09-27 | 2026-04-02 | Sound Pharmaceuticals Inc. | Cochlear implant eluting ebselen for treating hearing loss |
| CN120093774A (zh) * | 2025-03-20 | 2025-06-06 | 中国科学院杭州医学研究所 | Capilliposide A在制备防治年龄相关性黄斑变性的药物中的应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61257412A (ja) | 1985-05-09 | 1986-11-14 | Nippon Steel Corp | 転炉排ガス処理装置のスカ−トシ−ル装置 |
| DE3616923A1 (de) * | 1986-05-20 | 1987-11-26 | Nattermann A & Cie | Neue pharmazeutische verwendung von 2-phenyl-1,2-benzisoselenazol-3(2h)-on |
| DE3620674A1 (de) * | 1986-06-20 | 1987-12-23 | Nattermann A & Cie | Salbe zur behandlung von hauterkrankungen |
| US4778814A (en) | 1987-03-18 | 1988-10-18 | Ciba-Geigy Corporation | Method of treating ocular allergy by topical application of a 2-substituted-1,2-benzisoselenazol-3(2H)-one |
| US6342510B1 (en) | 1995-06-12 | 2002-01-29 | G. D. Searle & Co. | Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitors and a leukotriene B4 receptor antagonist |
| FR2740339B1 (fr) | 1995-10-26 | 1997-12-05 | Oreal | Utilisation d'au moins un inhibiteur de no-synthase dans le traitement des peaux sensibles |
| FR2757860B1 (fr) | 1996-12-27 | 1999-04-23 | Oxis International Sa | Composes organoselenies cycliques, leur preparation et leurs utilisations, notamment therapeutiques |
| JP2001261555A (ja) | 2000-03-17 | 2001-09-26 | Dai Ichi Seiyaku Co Ltd | 脳動脈中膜肥厚抑制剤 |
| FR2815541B1 (fr) * | 2000-10-24 | 2008-02-29 | Lipha | Utilisation d'inhibiteurs de l'apoptose des pericytes pour le traitement et/ou la prevention de la retinopathie diabetique |
| US7732487B2 (en) | 2001-11-19 | 2010-06-08 | Sucampo Ag | Method for treating a disease or condition responsive to opening of C1C-2 channel |
| US20040147581A1 (en) * | 2002-11-18 | 2004-07-29 | Pharmacia Corporation | Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy |
| WO2004069157A2 (en) | 2003-01-17 | 2004-08-19 | Ophthalmic Research Associates, Inc. | Combinational use of long-acting and short-acting anti-histamines for ocular allergies |
| WO2004112796A1 (en) * | 2003-06-20 | 2004-12-29 | Alcon, Inc. | Treatment of amd with combination of ingredients |
| JP2006104199A (ja) | 2004-09-13 | 2006-04-20 | Santen Pharmaceut Co Ltd | 角結膜障害治療剤 |
| PT1884234E (pt) | 2005-05-17 | 2012-07-26 | Santen Pharmaceutical Co Ltd | Agente profiláctico ou terapêutico para distúrbio corneano e conjuntival |
| JP5087233B2 (ja) * | 2005-05-17 | 2012-12-05 | 参天製薬株式会社 | 角結膜障害の予防または治療剤 |
| WO2009107759A1 (ja) | 2008-02-28 | 2009-09-03 | 参天製薬株式会社 | 視神経障害を伴う眼疾患の予防又は治療剤 |
-
2008
- 2008-05-23 WO PCT/JP2008/059503 patent/WO2008146721A1/ja not_active Ceased
- 2008-05-23 CN CN2008800174326A patent/CN101679328B/zh not_active Expired - Fee Related
- 2008-05-23 AT AT08764549T patent/ATE519756T1/de not_active IP Right Cessation
- 2008-05-23 CA CA002686560A patent/CA2686560A1/en not_active Abandoned
- 2008-05-23 EP EP08764549A patent/EP2163548B1/de not_active Not-in-force
- 2008-05-23 JP JP2008134900A patent/JP5314931B2/ja not_active Expired - Fee Related
- 2008-05-23 KR KR1020097022899A patent/KR20100016140A/ko not_active Ceased
- 2008-05-23 ES ES08764549T patent/ES2370751T3/es active Active
- 2008-05-23 RU RU2009148288/15A patent/RU2460526C2/ru not_active IP Right Cessation
- 2008-05-23 US US12/451,368 patent/US8309612B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008146721A1 (ja) | 2008-12-04 |
| JP2009007337A (ja) | 2009-01-15 |
| EP2163548A1 (de) | 2010-03-17 |
| CN101679328A (zh) | 2010-03-24 |
| CA2686560A1 (en) | 2008-12-04 |
| KR20100016140A (ko) | 2010-02-12 |
| JP5314931B2 (ja) | 2013-10-16 |
| EP2163548A4 (de) | 2010-06-30 |
| EP2163548B1 (de) | 2011-08-10 |
| ES2370751T3 (es) | 2011-12-22 |
| RU2460526C2 (ru) | 2012-09-10 |
| US8309612B2 (en) | 2012-11-13 |
| CN101679328B (zh) | 2011-12-28 |
| RU2009148288A (ru) | 2011-06-27 |
| US20100120873A1 (en) | 2010-05-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |