ATE520661T1 - Heterocyclische verbindungen mit quaternärem stickstoff zum nachweis von wässrigen monosacchariden in physiologischen flüssigkeiten - Google Patents
Heterocyclische verbindungen mit quaternärem stickstoff zum nachweis von wässrigen monosacchariden in physiologischen flüssigkeitenInfo
- Publication number
- ATE520661T1 ATE520661T1 AT04778295T AT04778295T ATE520661T1 AT E520661 T1 ATE520661 T1 AT E520661T1 AT 04778295 T AT04778295 T AT 04778295T AT 04778295 T AT04778295 T AT 04778295T AT E520661 T1 ATE520661 T1 AT E520661T1
- Authority
- AT
- Austria
- Prior art keywords
- quaternary nitrogen
- aqueous
- monosacharides
- detection
- heterocyclic compounds
- Prior art date
Links
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 title abstract 4
- 229910052757 nitrogen Inorganic materials 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title 1
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 239000007788 liquid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- ZADPBFCGQRWHPN-UHFFFAOYSA-N boronic acid Chemical compound OBO ZADPBFCGQRWHPN-UHFFFAOYSA-N 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 229930091371 Fructose Natural products 0.000 abstract 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 abstract 1
- 239000005715 Fructose Substances 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 239000012491 analyte Substances 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 1
- 230000004962 physiological condition Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
- Y10T436/144444—Glucose
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/19—Halogen containing
- Y10T436/193333—In aqueous solution
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48312403P | 2003-06-27 | 2003-06-27 | |
| US48320203P | 2003-06-27 | 2003-06-27 | |
| PCT/US2004/022717 WO2005000109A2 (en) | 2003-06-27 | 2004-06-28 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE520661T1 true ATE520661T1 (de) | 2011-09-15 |
Family
ID=33555598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04778295T ATE520661T1 (de) | 2003-06-27 | 2004-06-28 | Heterocyclische verbindungen mit quaternärem stickstoff zum nachweis von wässrigen monosacchariden in physiologischen flüssigkeiten |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US7718804B2 (de) |
| EP (1) | EP1644330B1 (de) |
| AT (1) | ATE520661T1 (de) |
| WO (1) | WO2005000109A2 (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2161575A3 (de) * | 2004-10-29 | 2010-03-31 | The University of Akron | Analyse von Glukose-Produkten mit Hilfe von Pyridinylboronsäure |
| WO2006052548A1 (en) * | 2004-11-05 | 2006-05-18 | University Of Maryland Biotechnology Institute | Metal-enhanced fluorescence from plastic substrates |
| US8034633B2 (en) * | 2004-11-19 | 2011-10-11 | University Of Maryland, Baltimore County | Microwave accelerated assays |
| EP1915610A4 (de) | 2005-06-15 | 2010-05-19 | Univ Maryland Biotech Inst | Bioassays mit plasmonischer streuung aus edelmetallnanostrukturen |
| US7988988B2 (en) * | 2005-11-21 | 2011-08-02 | Bausch & Lomb Incorporated | Contact lenses with mucin affinity |
| WO2012075220A2 (en) | 2010-12-01 | 2012-06-07 | University Of Maryland, Baltimore County | Assays for pathogen detection using microwaves for lysing and accelerating metal-enhanced fluorescence |
| US7832856B2 (en) | 2006-12-20 | 2010-11-16 | Bausch & Lomb Incorporated | Coatings and solutions for contact lenses |
| JP2010524208A (ja) | 2007-03-31 | 2010-07-15 | アドバンスド テクノロジー マテリアルズ，インコーポレイテッド | ウエハ再生のために材料を剥離する方法 |
| WO2011143288A2 (en) | 2010-05-11 | 2011-11-17 | University Of Maryland, Baltimore County | Tuning of metal enhanced emissions of long-lived luminescent compounds |
| WO2009148634A2 (en) * | 2008-01-30 | 2009-12-10 | University Of Maryland Biotechnology Institute | Conversion of just-continuous metallic films to large particulate substrates for metal-enhanced fluorescence |
| EP2257790B1 (de) | 2008-03-03 | 2016-12-07 | University Of Maryland Baltimore County | Verfahren und systeme für spannungsgesteuerte metallverstärkte fluoreszenz, chemilumineszenz oder biolumineszenz |
| WO2010005398A1 (en) * | 2008-07-09 | 2010-01-14 | Agency For Science, Technology And Research | Trapping glucose probe in pores of polymer |
| WO2010030828A2 (en) | 2008-09-11 | 2010-03-18 | University Of Maryland Biotechnology Institute | Sonication-assisted metal-enhanced fluorescence (samef)-based bioassays |
| CN102216757B (zh) | 2008-09-17 | 2014-02-12 | 马里兰大学,巴尔的摩县 | 等离激元电学 |
| WO2010096414A2 (en) | 2009-02-17 | 2010-08-26 | University Of Maryland Biotechnology Institute | Metal-enhanced bioluminescence: an approach for monitoring biological bioluminescent processes |
| WO2010096204A2 (en) | 2009-02-23 | 2010-08-26 | University Of Maryland Biotechnology Institute | Directional surface plasmon coupled fluorescence and chemiluminescence from thin films of nickel, iron or palladium and uses thereof |
| US20120177576A1 (en) * | 2009-09-18 | 2012-07-12 | Jun Jack Hu | Optical device and method for non-invasive real-time testing of blood sugar levels |
| EP2504687B1 (de) | 2009-11-25 | 2017-04-05 | University of Maryland, Baltimore County | System zur detektion von metallverstärkter fluoreszenz aus metallischen nanoburger-strukturen |
| US9810637B2 (en) | 2009-12-14 | 2017-11-07 | University Of Maryland, Baltimore County | Plasmonic electricity |
| US9459212B2 (en) | 2009-12-17 | 2016-10-04 | University Of Maryland, Baltimore County | Mixed-metal substrates for metal-enhanced fluorescence |
| US8113654B2 (en) | 2010-01-08 | 2012-02-14 | Benjamin David Enerson | Contact lens with visual indicator |
| US8541240B2 (en) | 2010-05-28 | 2013-09-24 | Florida State University Research Foundation, Inc. | Colorimetric and fluorimetric fluoride sensing |
| EP2686683A4 (de) | 2011-03-18 | 2014-10-01 | Chris Geddes | Metallverstärkte photolumineszenz aus kohlenstoffnanopunkten |
| US8735175B2 (en) | 2011-03-18 | 2014-05-27 | Chris D. Geddes | Multicolor microwave-accelerated metal-enhanced fluorescence (M-MAMEF) |
| US9051598B2 (en) * | 2011-05-02 | 2015-06-09 | The Hong Kong University Of Science And Technology | Specific detection of D-glucose by a tetraphenylethene-base fluorescent sensor |
| US9244012B2 (en) | 2011-09-26 | 2016-01-26 | University Of Maryland, Baltimore County | Enhanced luminescence from nanopolished surfaces and plate wells |
| KR20220164616A (ko) * | 2012-03-14 | 2022-12-13 | 머크 샤프 앤드 돔 코포레이션 | Cgrp 수용체 길항제의 제조 방법 |
| US9487523B2 (en) | 2012-03-14 | 2016-11-08 | Merck Sharp & Dohme Corp. | Process for making CGRP receptor antagonists |
| AU2013232191B2 (en) * | 2012-03-14 | 2017-03-30 | Merck Sharp & Dohme Llc | Bis-quarternary cinchona alkaloid salts as asymmetric phase transfer catalysts |
| US9816990B2 (en) | 2013-02-28 | 2017-11-14 | University Of Maryland, Baltimore County | Ultra-fast pathogen toxin detection assay based on microwave-accelerated metal-enhanced fluorescence |
| US20140371560A1 (en) | 2013-06-14 | 2014-12-18 | Google Inc. | Body-Mountable Devices and Methods for Embedding a Structure in a Body-Mountable Device |
| US9685689B1 (en) | 2013-06-27 | 2017-06-20 | Verily Life Sciences Llc | Fabrication methods for bio-compatible devices |
| US9307901B1 (en) | 2013-06-28 | 2016-04-12 | Verily Life Sciences Llc | Methods for leaving a channel in a polymer layer using a cross-linked polymer plug |
| US9028772B2 (en) | 2013-06-28 | 2015-05-12 | Google Inc. | Methods for forming a channel through a polymer layer using one or more photoresist layers |
| US10379050B2 (en) | 2015-01-13 | 2019-08-13 | University Of Maryland, Baltimore County | Spectral shifts and modifications in metal-enhanced fluorescence, phosphorescence and alpha-fluorescence |
| US10294451B2 (en) | 2015-04-22 | 2019-05-21 | University Of Maryland, Baltimore County | Flow and static lysing systems and methods for ultra-rapid isolation and fragmentation of biological materials by microwave irradiation |
| US11561180B2 (en) | 2015-07-22 | 2023-01-24 | University Of Maryland, Baltimore County | Hydrophilic coatings of plasmonic metals to enable low volume metal-enhanced fluorescence |
| CH711991B1 (de) * | 2015-12-22 | 2023-11-30 | Dosilab AG | Dosimetervorrichtung. |
| CN109715066B (zh) * | 2016-07-20 | 2022-04-05 | 巴尔的摩马里兰大学 | 基于硅氧烷水凝胶的荧光测定和接触镜片 |
| GB201805226D0 (en) * | 2018-03-29 | 2018-05-16 | Univ Dublin City | Boronic Acid Derivatives For Sugar-sensing Hydrogels |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3731681A (en) | 1970-05-18 | 1973-05-08 | Univ Minnesota | Implantable indusion pump |
| US4573994A (en) | 1979-04-27 | 1986-03-04 | The Johns Hopkins University | Refillable medication infusion apparatus |
| DK160633C (da) | 1985-05-15 | 1991-09-02 | Henning Munk Ejlersen | Slangepumpe, isaer til avendelse som insulinpumpe |
| US5075556A (en) * | 1989-12-01 | 1991-12-24 | Technicon Instruments Corporation | Acridine orange derivatives and their use in the quantitation of reticulocytes in whole blood |
| TW272976B (de) | 1993-08-06 | 1996-03-21 | Ciba Geigy Ag | |
| EP0655470B1 (de) | 1993-11-26 | 1999-05-12 | Novartis AG | Vernetzbare Copolymere und Hydrogele |
| US5712356A (en) | 1993-11-26 | 1998-01-27 | Ciba Vision Corporation | Cross-linkable copolymers and hydrogels |
| US5665840A (en) | 1994-11-18 | 1997-09-09 | Novartis Corporation | Polymeric networks from water-soluble prepolymers |
| EP0712867B1 (de) | 1994-11-18 | 1999-07-14 | Novartis AG | Polymere Netzwerke aus wasserlöslichen Präpolymeren |
| TW349967B (en) | 1995-02-03 | 1999-01-11 | Novartis Ag | Process for producing contact lenses and a cross-linkable polyvinylalcohol used therefor |
| EP0807270B1 (de) | 1995-02-03 | 1999-03-31 | Novartis AG | Vernetzte polymere enthaltend ester- oder amidgruppen |
| EP0932635B1 (de) | 1996-10-21 | 2001-07-11 | Novartis AG | Vernetzbare polymere |
| TW425403B (en) | 1997-02-04 | 2001-03-11 | Novartis Ag | Branched polyurethane (meth)acrylate prepolymers, opthal-mic mouldings derived therefrom and processes for their manufacture |
| EP0867456A1 (de) | 1997-02-04 | 1998-09-30 | Novartis AG | Ophthalmischer Formkörper |
| ES2175698T3 (es) | 1997-02-21 | 2002-11-16 | Novartis Ag | Articulos de moldeo oftalmicos. |
| US5957890A (en) | 1997-06-09 | 1999-09-28 | Minimed Inc. | Constant flow medication infusion pump |
| JP4616473B2 (ja) | 1997-09-16 | 2011-01-19 | ノバルティス アーゲー | 架橋結合可能なポリ尿素ポリマー類 |
| AU1633300A (en) | 1998-11-25 | 2000-06-13 | University Of Maryland | Proof mass support for accelerometers |
| CA2381520C (en) | 1999-08-26 | 2009-05-26 | Novartis Ag | Ocular analyte sensor |
| US20020007113A1 (en) | 1999-08-26 | 2002-01-17 | March Wayne Front | Ocular analyte sensor |
| AU2001251210A1 (en) | 2000-04-04 | 2001-10-15 | Medtronic Minimed, Inc. | Saccharide sensing molecules having enhanced fluorescent properties |
| US6368864B1 (en) * | 2000-05-05 | 2002-04-09 | Coulter International Corp. | Dyes and methods of reticulocyte enumeration |
| US6627177B2 (en) * | 2000-12-05 | 2003-09-30 | The Regents Of The University Of California | Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof |
| US20040087842A1 (en) | 2002-05-30 | 2004-05-06 | Lakowicz Joseph R. | Fluorescent probes for saccharrides |
| US20050015237A1 (en) | 2003-07-17 | 2005-01-20 | Fathi Debili | Process, computerized device and computer program for assisting the vowelization of Arabic language words |
| EP1671118B1 (de) * | 2003-09-17 | 2011-11-02 | University of Maryland, Baltimore County | Cyanid wahrnehmende verbindungen und verwendungen davon |
| US7906293B2 (en) * | 2007-04-09 | 2011-03-15 | Abbott Laboratories | Acridinium phenyl esters useful in the analysis of biological |
-
2004
- 2004-06-28 AT AT04778295T patent/ATE520661T1/de not_active IP Right Cessation
- 2004-06-28 EP EP04778295A patent/EP1644330B1/de not_active Expired - Lifetime
- 2004-06-28 WO PCT/US2004/022717 patent/WO2005000109A2/en not_active Ceased
-
2005
- 2005-12-27 US US11/318,663 patent/US7718804B2/en not_active Expired - Fee Related
-
2010
- 2010-05-18 US US12/781,899 patent/US8338602B2/en not_active Expired - Fee Related
-
2012
- 2012-12-24 US US13/726,445 patent/US8569502B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7718804B2 (en) | 2010-05-18 |
| WO2005000109A2 (en) | 2005-01-06 |
| EP1644330B1 (de) | 2011-08-17 |
| US20070020182A1 (en) | 2007-01-25 |
| WO2005000109A3 (en) | 2005-03-10 |
| EP1644330A4 (de) | 2009-06-03 |
| EP1644330A2 (de) | 2006-04-12 |
| US8569502B2 (en) | 2013-10-29 |
| US8338602B2 (en) | 2012-12-25 |
| US20130210158A1 (en) | 2013-08-15 |
| US20100297016A1 (en) | 2010-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |