ATE520714T1 - Glucagonanaloga - Google Patents

Glucagonanaloga

Info

Publication number
ATE520714T1
ATE520714T1 AT08762369T AT08762369T ATE520714T1 AT E520714 T1 ATE520714 T1 AT E520714T1 AT 08762369 T AT08762369 T AT 08762369T AT 08762369 T AT08762369 T AT 08762369T AT E520714 T1 ATE520714 T1 AT E520714T1
Authority
AT
Austria
Prior art keywords
methods
glucagon analogue
peptides
glucagon
glp
Prior art date
Application number
AT08762369T
Other languages
English (en)
Inventor
Ditte Riber
Eddi Meier
Trine Skovlund Ryge Neerup
Jens Rosengren Daugaard
Original Assignee
Zealand Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0711673A external-priority patent/GB0711673D0/en
Priority claimed from EP07016032A external-priority patent/EP2025684A1/de
Application filed by Zealand Pharma As filed Critical Zealand Pharma As
Application granted granted Critical
Publication of ATE520714T1 publication Critical patent/ATE520714T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Child & Adolescent Psychology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT08762369T 2007-06-15 2008-06-16 Glucagonanaloga ATE520714T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0711673A GB0711673D0 (en) 2007-06-15 2007-06-15 Glucagon analogues
EP07016032A EP2025684A1 (de) 2007-08-15 2007-08-15 Glucagonanaloga
US18807P 2007-10-24 2007-10-24
PCT/GB2008/002041 WO2008152403A1 (en) 2007-06-15 2008-06-16 Glucagon analogues

Publications (1)

Publication Number Publication Date
ATE520714T1 true ATE520714T1 (de) 2011-09-15

Family

ID=39709376

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08762369T ATE520714T1 (de) 2007-06-15 2008-06-16 Glucagonanaloga

Country Status (6)

Country Link
US (1) US7994122B2 (de)
EP (1) EP2158214B1 (de)
JP (1) JP5385266B2 (de)
AT (1) ATE520714T1 (de)
DK (1) DK2158214T3 (de)
WO (1) WO2008152403A1 (de)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2507098T3 (es) 2005-11-07 2014-10-14 Indiana University Research And Technology Corporation Análogos de glucagón que muestran solubilidad y estabilidad fisiológicas
KR20150116465A (ko) 2007-02-15 2015-10-15 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 글루카곤/glp-1 수용체 공동-항진물질
WO2009058734A1 (en) * 2007-10-30 2009-05-07 Indiana University Research And Technology Corporation Compounds exhibiting glucagon antagonist and glp-1 agonist activity
US8546327B2 (en) 2008-06-17 2013-10-01 Indiana University Research And Technology Corporation Glucagon/GLP-1 receptor co-agonists
PL2300035T3 (pl) * 2008-06-17 2016-04-29 Univ Indiana Res & Tech Corp Mieszani agoniści na bazie GIP do leczenia zaburzeń metabolicznych i otyłości
MX2011006314A (es) 2008-12-15 2011-09-22 Zealand Pharma As Analogos de glucagon.
WO2010070253A1 (en) 2008-12-15 2010-06-24 Zealand Pharma A/S Glucagon analogues
CA2747197A1 (en) 2008-12-15 2010-06-24 Zealand Pharma A/S Glucagon analogues
US8685919B2 (en) 2008-12-15 2014-04-01 Zealand Pharma A/S Glucagon analogues
AR074811A1 (es) 2008-12-19 2011-02-16 Univ Indiana Res & Tech Corp Profarmaco de peptido de la superfamilia de glucagon basados en amida
MX2011013625A (es) * 2009-06-16 2012-01-20 Univ Indiana Res & Tech Corp Compuestos glucagon activo de receptor de gip.
PT2454282E (pt) 2009-07-13 2015-06-23 Zealand Pharma As Análogos de glucagão acilados
AR079344A1 (es) 2009-12-22 2012-01-18 Lilly Co Eli Analogo peptidico de oxintomodulina, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para tratar diabetes no insulinodependiente y/u obesidad
AR079345A1 (es) 2009-12-22 2012-01-18 Lilly Co Eli Analogo peptidico de oxintomodulina
EP2525809B1 (de) * 2010-01-20 2016-08-03 Zealand Pharma A/S Glukagon-glp1 doppelagonisten zur behandlung von herzkrankheiten
MX2012008603A (es) 2010-01-27 2013-01-25 Univ Indiana Res & Tech Corp Conjugados de antagonista de glucagon-agonista de gip y composiciones para el tratamiento de desordenes metabolicos y obesidad.
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
BR112012024379A2 (pt) 2010-03-26 2017-01-10 Novo Nordisk As "peptídeos glucagon, seu uso, bem como composição farmacêutica"
JP2013523620A (ja) 2010-03-26 2013-06-17 ノヴォ ノルディスク アー/エス 新規のグルカゴンアナログ
DE102010015123A1 (de) 2010-04-16 2011-10-20 Sanofi-Aventis Deutschland Gmbh Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
AU2011247452B2 (en) 2010-04-27 2016-03-17 Zealand Pharma A/S Peptide conjugates of GLP-1 receptor agonists and gastrin and their use
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
UY33462A (es) * 2010-06-23 2012-01-31 Zealand Pharma As Analogos de glucagon
US9169310B2 (en) 2010-06-24 2015-10-27 Zealand Pharma A/S Glucagon analogues
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
KR101382593B1 (ko) 2010-07-21 2014-04-10 한미사이언스 주식회사 신규한 지속형 글루카곤 결합체 및 이를 포함하는 비만 예방 및 치료용 약학적 조성물
EA201390941A1 (ru) 2010-12-22 2013-12-30 Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн Аналоги глюкагона, проявляющие активность на рецепторе gip
MX2013008005A (es) 2011-01-20 2013-08-21 Zealand Pharma As Combinacion de analogos de glucagon acilados con analogos de insulina.
WO2012121746A2 (en) * 2011-03-09 2012-09-13 The General Hospital Corporation Imaging beta cell mass
BR112013024076A2 (pt) 2011-03-28 2016-12-06 Novo Nordisk As análogos de glucagon
WO2012150503A2 (en) 2011-05-03 2012-11-08 Zealand Pharma A/S Glu-glp-1 dual agonist signaling-selective compounds
WO2012153196A2 (en) 2011-05-10 2012-11-15 Zealand Pharma A/S Glu-glp-1 dual agonist signaling-selective compounds
WO2012177443A2 (en) 2011-06-22 2012-12-27 Indiana University Research And Technology Corporation Glucagon/glp-1 receptor co-agonists
RU2014101697A (ru) 2011-06-22 2015-07-27 Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн Коагонисты рецепторов глюкагона/glp-1
EP2729493B1 (de) 2011-07-04 2020-06-10 IP2IPO Innovations Limited Neue verbindungen und ihre auswirkungen auf das ernährungsverhalten
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2567959B1 (de) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridin-4-carbonsäureamid-derivate als kinaseinhibitoren
JP6352806B2 (ja) 2011-09-23 2018-07-04 ノヴォ ノルディスク アー/エス 新規のグルカゴン類似体
EP2760862B1 (de) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridin-4-carbonsäureamidderivate als kinaseinhibitoren
MX2014005351A (es) 2011-11-03 2014-05-28 Zealand Pharma As Conjugados de gastrina peptidicos de agonistas de receptor glp-1.
AP2014007797A0 (en) 2011-12-23 2014-07-31 Boehringer Ingelheim Int Glucagon analogues
WO2013098408A1 (en) 2011-12-30 2013-07-04 Zealand Pharma A/S Glucagon and cck receptor agonist peptide conjugates
JP6228187B2 (ja) 2012-05-03 2017-11-08 ジーランド ファーマ アクティーゼルスカブ Gip−glp−1デュアルアゴニスト化合物及び方法
JP2015525226A (ja) 2012-06-14 2015-09-03 サノフイ エキセンディン−4ペプチドアナログ
JP6534927B2 (ja) 2012-07-23 2019-06-26 ジーランド ファーマ アクティーゼルスカブ グルカゴン類似体
TWI608013B (zh) 2012-09-17 2017-12-11 西蘭製藥公司 升糖素類似物
WO2014049610A2 (en) 2012-09-26 2014-04-03 Cadila Healthcare Limited Peptides as gip, glp-1 and glucagon receptors triple-agonist
UA116217C2 (uk) 2012-10-09 2018-02-26 Санофі Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
EP2911655A1 (de) 2012-10-24 2015-09-02 INSERM (Institut National de la Santé et de la Recherche Médicale) Tpl2-kinasehemmer zur vorbeugung oder behandlung von diabetes und zur förderung des überlebens von betazellen
LT2934568T (lt) 2012-12-21 2018-02-12 Sanofi Dvigubi glp1/gip arba trigubi glp/gip/gliukagono agonistai
JP6538645B2 (ja) 2013-03-14 2019-07-03 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation インスリン‐インクレチン複合物
CN105102427B (zh) 2013-03-21 2018-09-07 赛诺菲-安万特德国有限公司 含有环状酰亚胺的肽产物的合成
HUE034308T2 (en) 2013-03-21 2018-02-28 Sanofi Aventis Deutschland Preparation of hydantoin-containing peptide products
AR095986A1 (es) 2013-04-03 2015-11-25 Sanofi Sa Proteínas modificadas que regulan glucosa en sangre con perfil alterado de actividad farmacológica y preparación de las mismas
CA2909581A1 (en) 2013-04-18 2014-10-23 Novo Nordisk A/S Stable, protracted glp-1/glucagon receptor co-agonists for medical use
US9988429B2 (en) 2013-10-17 2018-06-05 Zealand Pharma A/S Glucagon analogues
PE20160683A1 (es) 2013-10-17 2016-07-21 Zealand Pharma As Analogos de glucagon acilados
US10131702B2 (en) 2013-11-06 2018-11-20 Zealand Pharma A/S Glucagon-GLP-1-GIP triple agonist compounds
MX2016005556A (es) 2013-11-06 2016-07-15 Zealand Pharma As Compuestos agonistas duales de gip-glp-1 y procedimientos.
EP3080152A1 (de) 2013-12-13 2016-10-19 Sanofi Nicht-acylierte exendin-4-peptidanaloga
EP3080150B1 (de) 2013-12-13 2018-08-01 Sanofi Exendin-4-peptidanaloga als duale glp-1/gip-rezeptoragonisten
TW201609797A (zh) 2013-12-13 2016-03-16 賽諾菲公司 雙重glp-1/升糖素受體促效劑
EP3080155A1 (de) 2013-12-13 2016-10-19 Sanofi Exendin-4-peptidanaloga als duale glp-1/glucagon-rezeptoragonisten
WO2015086729A1 (en) 2013-12-13 2015-06-18 Sanofi Dual glp-1/gip receptor agonists
CA2939763A1 (en) 2014-02-18 2015-08-27 Novo Nordisk A/S Stable glucagon analogues and use for treatment of hypoglycaemia
TW201625669A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑
TW201625670A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自exendin-4之雙重glp-1/升糖素受體促效劑
TW201625668A (zh) 2014-04-07 2016-07-16 賽諾菲公司 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物
US10570184B2 (en) 2014-06-04 2020-02-25 Novo Nordisk A/S GLP-1/glucagon receptor co-agonists for medical use
US9932381B2 (en) 2014-06-18 2018-04-03 Sanofi Exendin-4 derivatives as selective glucagon receptor agonists
CN108271356A (zh) 2014-09-24 2018-07-10 印第安纳大学研究及科技有限公司 肠降血糖素-胰岛素缀合物
ES2883345T3 (es) 2014-10-29 2021-12-07 Zealand Pharma As Compuestos agonistas del GIP y métodos
MX2017008569A (es) 2014-12-30 2017-10-20 Hanmi Pharm Ind Co Ltd Derivados de glucagon con estabilidad mejorada.
US10213487B2 (en) 2015-02-17 2019-02-26 Eli Lilly And Company Nasal powder formulation for treatment of hypoglycemia
CA2979950A1 (en) 2015-03-18 2016-09-22 Zealand Pharma A/S Amylin analogues
US10426818B2 (en) 2015-03-24 2019-10-01 Inserm (Institut National De La Sante Et De La Recherche Medicale) Method and pharmaceutical composition for use in the treatment of diabetes
WO2016168388A2 (en) 2015-04-14 2016-10-20 Palatin Technologies, Inc. Therapies for obesity, diabetes and related indications
AU2016247499B2 (en) 2015-04-16 2020-09-03 Zealand Pharma A/S Acylated glucagon analogue
AR105319A1 (es) 2015-06-05 2017-09-27 Sanofi Sa Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
WO2016198628A1 (en) 2015-06-12 2016-12-15 Sanofi Non-acylated exendin-4 derivatives as dual glp-1/glucagon receptor agonists
WO2016198624A1 (en) 2015-06-12 2016-12-15 Sanofi Exendin-4 derivatives as trigonal glp-1/glucagon/gip receptor agonists
CN108025041A (zh) 2015-06-30 2018-05-11 韩美药品株式会社 胰高血糖素衍生物和包含其长效缀合物的组合物
TW201706291A (zh) 2015-07-10 2017-02-16 賽諾菲公司 作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物
MX2018008128A (es) 2015-12-31 2018-12-06 Hanmi Pharm Ind Co Ltd Conjugado persistente de triple activador que activa el receptor de glucagon, glp-1 y gip.
GB2566228A (en) * 2016-06-09 2019-03-06 AmideBio LLC Glucagon analogs and methods of use thereof
PE20190355A1 (es) * 2016-06-29 2019-03-07 Hanmi Pharm Ind Co Ltd Derivado de glucagon, conjugado del mismo, composicion que comprende el mismo y uso terapeutico del mismo
MA45843B1 (fr) 2016-08-05 2021-06-30 Boehringer Ingelheim Int Dérivés d'oxadiazolopyridine utilisés comme inhibiteurs de la ghréline o-acyl transférase (chèvre)
AR109514A1 (es) 2016-09-09 2018-12-19 Zealand Pharma As Análogos de amilina
TW201832783A (zh) 2016-12-02 2018-09-16 法商賽諾菲公司 包含glp-1/胰高血糖素雙重激動劑、連接子和透明質酸的接合物
BR112019010624A2 (pt) 2016-12-09 2019-10-22 Zealand Pharma As agonistas duplos de glp-1/glp-2 acilados e composição
EA202091804A1 (ru) 2018-02-02 2020-12-24 Бёрингер Ингельхайм Интернациональ Гмбх Гетероциклил-замещенные оксадиазолопиридиновые производные для применения в качестве ингибиторов грелин-о-ацилтрансферазы (goat)
EP3746443B1 (de) 2018-02-02 2022-07-06 Boehringer Ingelheim International GmbH Triazolopyrimidinderivate zur verwendung als inhibitoren der ghrelin-o-acyl-transferase (goat)
WO2019149657A1 (en) 2018-02-02 2019-08-08 Boehringer Ingelheim International Gmbh Benzyl-, (pyridin-3-yl)methyl- or (pyridin-4-yl)methyl-substituted oxadiazolopyridine derivatives as ghrelin o-acyl transferase (goat) inhibitors
EP3746449B1 (de) 2018-02-02 2022-03-30 Boehringer Ingelheim International GmbH Pyrazol- und indazol-substituierte oxadiazolopyridinderivate zur verwendung als inhibitoren der ghrelin-o-acyltransferase (goat)
WO2020125744A1 (zh) 2018-12-21 2020-06-25 江苏恒瑞医药股份有限公司 双特异性蛋白
TWI771669B (zh) 2019-04-26 2022-07-21 美商美國禮來大藥廠 製備穩定胜肽調配物之方法
CN114641303A (zh) 2019-11-11 2022-06-17 勃林格殷格翰国际有限公司 Npy2受体激动剂
EP4153599B1 (de) 2020-05-22 2024-03-13 Boehringer Ingelheim International GmbH Verfahren zur herstellung von alkyl-7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-carboxylaten
HUE069479T2 (hu) 2020-05-22 2025-04-28 Boehringer Ingelheim Int Alkil 7-amino-5-metil-[1,2,5]-oxadiazolo[3,4-b]piridin-karboxilát folyamatos elõállítási eljárása
CR20230074A (es) 2020-08-07 2023-04-19 Boehringer Ingelheim Int Agonistas del receptor npy2 solubles
WO2022232168A1 (en) 2021-04-27 2022-11-03 Aardvark Therapeutics, Inc. Combination of bitter receptor agonist and gut-signaling compound
GB202109087D0 (en) 2021-06-24 2021-08-11 Norwegian Univ Sci & Tech Ntnu Therapeutic methods and devices

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ202757A (en) 1981-12-23 1985-11-08 Novo Industri As Peptides and medicaments
AU723268B2 (en) 1996-09-09 2000-08-24 Zealand Pharma A/S Improved solid-phase peptide synthesis and agent for use in such synthesis
EP1066314B1 (de) 1997-11-14 2007-12-26 Amylin Pharmaceuticals, Inc. Neuartige exendin agonisten
WO1999046283A1 (en) 1998-03-09 1999-09-16 Zealand Pharmaceuticals A/S Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
EP1076066A1 (de) 1999-07-12 2001-02-14 Zealand Pharmaceuticals A/S Peptide zur Senkung des Blutglukosespiegels
GB0121709D0 (en) * 2001-09-07 2001-10-31 Imp College Innovations Ltd Food inhibition agent
GB0300571D0 (en) 2003-01-10 2003-02-12 Imp College Innovations Ltd Modification of feeding behaviour
KR101349808B1 (ko) 2005-06-13 2014-02-13 임페리얼 이노베이션스 리미티드 섭취행동에 관한 신규 화합물들 및 이들의 효능
US20090202497A1 (en) 2005-08-23 2009-08-13 The General Hospital Corporation Use of glp-1, glp-1 derivatives or glp-1 fragments for skin regeneration, stimulation of hair growth, or treatment of diabetes
KR20150116465A (ko) 2007-02-15 2015-10-15 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 글루카곤/glp-1 수용체 공동-항진물질
EP2025684A1 (de) 2007-08-15 2009-02-18 Zealand Pharma A/S Glucagonanaloga

Also Published As

Publication number Publication date
EP2158214A1 (de) 2010-03-03
JP5385266B2 (ja) 2014-01-08
EP2158214B1 (de) 2011-08-17
US20100204105A1 (en) 2010-08-12
JP2010529849A (ja) 2010-09-02
US7994122B2 (en) 2011-08-09
WO2008152403A1 (en) 2008-12-18
DK2158214T3 (da) 2011-12-05

Similar Documents

Publication Publication Date Title
ATE520714T1 (de) Glucagonanaloga
MX2011006315A (es) Analogos de glucagon.
MX2011006320A (es) Analogos de glucagon.
TN2011000295A1 (en) Glucagon analogues
MX2011006314A (es) Analogos de glucagon.
MY188182A (en) Acylated glucagon analogues
TN2012000560A1 (en) Glucagon analogues
TN2012000567A1 (en) Glucagon analogues
WO2014041195A8 (en) Glucagon analogues
WO2015055802A3 (en) Glucagon analogues
PH12016500675A1 (en) Acylated glucagon analogues
HK1200369A1 (en) Glucagon analogues
MX2017012864A (es) Analogo acilado del glucagon.
TN2011000667A1 (en) Acylated glucagon analogues
WO2012145281A3 (en) Methods and compositions suitable for preventing and treating hyperleptinemia
CY1116448T1 (el) Ακυλιωμενα αναλογα γλυκαγονης

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 2158214

Country of ref document: EP