ATE520714T1 - Glucagonanaloga - Google Patents

Glucagonanaloga

Info

Publication number: ATE520714T1
Authority: AT; Austria
Prior art keywords: methods; glucagon analogue; peptides; glucagon; glp
Prior art date: 2007-06-15

Application number

AT08762369T

Other languages

English (en)

Inventor

Ditte Riber

Eddi Meier

Trine Skovlund Ryge Neerup

Jens Rosengren Daugaard

Original Assignee

Zealand Pharma As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-15

Filing date

2008-06-16

Publication date

2011-09-15

2007-06-15 Priority claimed from GB0711673A external-priority patent/GB0711673D0/en

2007-08-15 Priority claimed from EP07016032A external-priority patent/EP2025684A1/de

2008-06-16 Application filed by Zealand Pharma As filed Critical Zealand Pharma As

2011-09-15 Application granted granted Critical

2011-09-15 Publication of ATE520714T1 publication Critical patent/ATE520714T1/de

Links

MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical class C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 title abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
208000030814 Eating disease Diseases 0.000 abstract 1
208000004930 Fatty Liver Diseases 0.000 abstract 1
208000019454 Feeding and Eating disease Diseases 0.000 abstract 1
102000007446 Glucagon-Like Peptide-1 Receptor Human genes 0.000 abstract 1
108010086246 Glucagon-Like Peptide-1 Receptor Proteins 0.000 abstract 1
101500028775 Homo sapiens Glucagon Proteins 0.000 abstract 1
208000001145 Metabolic Syndrome Diseases 0.000 abstract 1
208000008589 Obesity Diseases 0.000 abstract 1
201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 abstract 1
230000001476 alcoholic effect Effects 0.000 abstract 1
235000014632 disordered eating Nutrition 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
235000020824 obesity Nutrition 0.000 abstract 1
230000001737 promoting effect Effects 0.000 abstract 1
230000004584 weight gain Effects 0.000 abstract 1
235000019786 weight gain Nutrition 0.000 abstract 1
230000004580 weight loss Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Toxicology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Child & Adolescent Psychology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT08762369T 2007-06-15 2008-06-16 Glucagonanaloga ATE520714T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB0711673A GB0711673D0 (en)	2007-06-15	2007-06-15	Glucagon analogues
EP07016032A EP2025684A1 (de)	2007-08-15	2007-08-15	Glucagonanaloga
US18807P	2007-10-24	2007-10-24
PCT/GB2008/002041 WO2008152403A1 (en)	2007-06-15	2008-06-16	Glucagon analogues

Publications (1)

Publication Number	Publication Date
ATE520714T1 true ATE520714T1 (de)	2011-09-15

Family

ID=39709376

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT08762369T ATE520714T1 (de)	2007-06-15	2008-06-16	Glucagonanaloga

Country Status (6)

Country	Link
US (1)	US7994122B2 (de)
EP (1)	EP2158214B1 (de)
JP (1)	JP5385266B2 (de)
AT (1)	ATE520714T1 (de)
DK (1)	DK2158214T3 (de)
WO (1)	WO2008152403A1 (de)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2913805A1 (en)	2005-11-07	2007-05-18	Indiana University Research And Technology Corporation	Glucagon analogs exhibiting physiological solubility and stability
NZ578948A (en)	2007-02-15	2012-03-30	Univ Indiana Res & Tech Corp	Glucagon/glp-1 receptor co-agonists
WO2009058734A1 (en) *	2007-10-30	2009-05-07	Indiana University Research And Technology Corporation	Compounds exhibiting glucagon antagonist and glp-1 agonist activity
ES2558842T3 (es) *	2008-06-17	2016-02-09	Indiana University Research And Technology Corporation	Agonistas mixtos a base de GIP para el tratamiento de trastornos metabólicos y obesidad
CA2728284C (en)	2008-06-17	2019-09-10	Richard D. Dimarchi	Glucagon/glp-1 receptor co-agonists
ES2502218T3 (es)	2008-12-15	2014-10-03	Zealand Pharma A/S	Análogos de glucagón
US8642540B2 (en) *	2008-12-15	2014-02-04	Zealand Pharma A/S	Glucagon analogues
MA32970B1 (fr)	2008-12-15	2012-01-02	Zealand Pharma As	Analogues du glucagon
AU2008365557A1 (en)	2008-12-15	2011-07-21	Zealand Pharma A/S	Glucagon analogues
EP2376097A4 (de)	2008-12-19	2012-10-03	Univ Indiana Res & Tech Corp	Amidbasierte peptid-prodrugs der glucagon-superfamilie
WO2010148089A1 (en)	2009-06-16	2010-12-23	Indiana University Research And Technology Corporation	Gip receptor-active glucagon compounds
JP6054742B2 (ja)	2009-07-13	2016-12-27	ジーランドファーマアクティーゼルスカブ	アシル化グルカゴン類似体
AR079344A1 (es)	2009-12-22	2012-01-18	Lilly Co Eli	Analogo peptidico de oxintomodulina, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para tratar diabetes no insulinodependiente y/u obesidad
JO2976B1 (en)	2009-12-22	2016-03-15	ايلي ليلي اند كومباني	Axentomodulin polypeptide
WO2011088837A1 (en) *	2010-01-20	2011-07-28	Zealand Pharma A/S	Treatment of cardiac conditions
KR20120123443A (ko)	2010-01-27	2012-11-08	인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션	대사 장애 및 비만 치료용 글루카곤 길항제-ｇｉｐ 항진제 콘쥬게이트
WO2011107494A1 (de)	2010-03-03	2011-09-09	Sanofi	Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2011117417A1 (en)	2010-03-26	2011-09-29	Novo Nordisk A/S	Novel glucagon analogues
KR20130018410A (ko)	2010-03-26	2013-02-21	노보 노르디스크 에이/에스	새로운 글루카곤 유사체
DE102010015123A1 (de)	2010-04-16	2011-10-20	Sanofi-Aventis Deutschland Gmbh	Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
CN103003300B (zh)	2010-04-27	2017-06-09	西兰制药公司	Glp‑1受体激动剂和胃泌素的肽缀合物及其用途
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
AR081975A1 (es) *	2010-06-23	2012-10-31	Zealand Pharma As	Analogos de glucagon
CA2802897A1 (en) *	2010-06-24	2011-12-29	Zealand Pharma A/S	Glucagon analogues
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
KR101382593B1 (ko)	2010-07-21	2014-04-10	한미사이언스 주식회사	신규한 지속형 글루카곤 결합체 및 이를 포함하는 비만 예방 및 치료용 약학적 조성물
NZ612297A (en)	2010-12-22	2015-10-30	Univ Indiana Res & Tech Corp	Glucagon analogs exhibiting gip receptor activity
EA201390796A1 (ru)	2011-01-20	2014-07-30	Зилэнд Фарма А/С	Применение ацилированного аналога глюкагона
WO2012121746A2 (en) *	2011-03-09	2012-09-13	The General Hospital Corporation	Imaging beta cell mass
RU2013145013A (ru)	2011-03-28	2015-05-10	Ново Нордиск А/С	Новые аналоги глюкагона
WO2012150503A2 (en)	2011-05-03	2012-11-08	Zealand Pharma A/S	Glu-glp-1 dual agonist signaling-selective compounds
WO2012153196A2 (en)	2011-05-10	2012-11-15	Zealand Pharma A/S	Glu-glp-1 dual agonist signaling-selective compounds
JP6184404B2 (ja)	2011-06-22	2017-08-23	インディアナユニヴァーシティリサーチアンドテクノロジーコーポレイション	グルカゴン／ｇｌｐ−１レセプターコアゴニスト
CN103857408B (zh)	2011-06-22	2017-04-12	印第安那大学科技研究公司	胰高血糖素/glp‑1受体协同激动剂
WO2013004983A1 (en)	2011-07-04	2013-01-10	Imperial Innovations Limited	Novel compounds and their effects on feeding behaviour
WO2013037390A1 (en)	2011-09-12	2013-03-21	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2567959B1 (de)	2011-09-12	2014-04-16	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridin-4-carbonsäureamid-derivate als kinaseinhibitoren
MX354705B (es)	2011-09-23	2018-03-16	Novo Nordisk As	Analogos de glucagon novedosos.
EP2760862B1 (de)	2011-09-27	2015-10-21	Sanofi	6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridin-4-carbonsäureamidderivate als kinaseinhibitoren
KR20140100947A (ko)	2011-11-03	2014-08-18	질랜드 파마 에이/에스	Ｇｌｐ-1 수용체 효능제 펩타이드 가스트린 접합체들
KR20140114845A (ko)	2011-12-23	2014-09-29	질랜드 파마 에이/에스	글루카곤 유사체
WO2013098408A1 (en)	2011-12-30	2013-07-04	Zealand Pharma A/S	Glucagon and cck receptor agonist peptide conjugates
CA2872314C (en)	2012-05-03	2021-08-31	Zealand Pharma A/S	Gip-glp-1 dual agonist compounds and methods
JP2015525226A (ja)	2012-06-14	2015-09-03	サノフイ	エキセンディン−４ペプチドアナログ
NZ704043A (en)	2012-07-23	2017-07-28	Zealand Pharma As	Glucagon analogues
TWI608013B (zh)	2012-09-17	2017-12-11	西蘭製藥公司	升糖素類似物
AR092873A1 (es)	2012-09-26	2015-05-06	Cadila Healthcare Ltd	Peptidos como agonistas triples de los receptores de gip, glp-1 y glugagon
UA116217C2 (uk)	2012-10-09	2018-02-26	Санофі	Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
CN105142621A (zh)	2012-10-24	2015-12-09	国家健康科学研究所	用于预防或治疗糖尿病和促进β-细胞存活的TPL2激酶抑制剂
HUE035803T2 (en)	2012-12-21	2018-05-28	Sanofi Sa	Dual GLP1 / GIP or trigonal GLP1 / GIP / glucagon agonists
JP6538645B2 (ja)	2013-03-14	2019-07-03	インディアナユニバーシティーリサーチアンドテクノロジーコーポレーションＩｎｄｉａｎａＵｎｉｖｅｒｓｉｔｙＲｅｓｅａｒｃｈＡｎｄＴｅｃｈｎｏｌｏｇｙＣｏｒｐｏｒａｔｉｏｎ	インスリン‐インクレチン複合物
US10450343B2 (en)	2013-03-21	2019-10-22	Sanofi-Aventis Deutschland Gmbh	Synthesis of cyclic imide containing peptide products
HUE034308T2 (en)	2013-03-21	2018-02-28	Sanofi Aventis Deutschland	Preparation of hydantoin-containing peptide products
AR095986A1 (es)	2013-04-03	2015-11-25	Sanofi Sa	Proteínas modificadas que regulan glucosa en sangre con perfil alterado de actividad farmacológica y preparación de las mismas
BR112015025464A2 (pt)	2013-04-18	2017-10-10	Novo Nordisk As	coagonistas do receptor de glp-1/glucagon estáveis, prolongados para uso médico
AR098065A1 (es)	2013-10-17	2016-04-27	Zealand Pharma As	Análogos de glucagón acilados
US9988429B2 (en)	2013-10-17	2018-06-05	Zealand Pharma A/S	Glucagon analogues
CA2929459C (en)	2013-11-06	2022-05-03	Zealand Pharma A/S	Gip-glp-1 dual agonist compounds and methods
AU2014345570B2 (en)	2013-11-06	2019-01-24	Zealand Pharma A/S	Glucagon-GLP-1-GIP triple agonist compounds
TW201609797A (zh)	2013-12-13	2016-03-16	賽諾菲公司	雙重ｇｌｐ－１／升糖素受體促效劑
WO2015086731A1 (en)	2013-12-13	2015-06-18	Sanofi	Exendin-4 peptide analogues as dual glp-1/glucagon receptor agonists
EP3080154B1 (de)	2013-12-13	2018-02-07	Sanofi	Duale glp-1/gip-rezeptoragonisten
WO2015086730A1 (en)	2013-12-13	2015-06-18	Sanofi	Non-acylated exendin-4 peptide analogues
WO2015086728A1 (en)	2013-12-13	2015-06-18	Sanofi	Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
AR100306A1 (es)	2014-02-18	2016-09-28	Novo Nordisk As	Análogos de glucagón estables y uso para el tratamiento de la hipoglucemia
TW201625669A (zh)	2014-04-07	2016-07-16	賽諾菲公司	衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑
TW201625670A (zh)	2014-04-07	2016-07-16	賽諾菲公司	衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑
TW201625668A (zh)	2014-04-07	2016-07-16	賽諾菲公司	作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物
JP2017525656A (ja)	2014-06-04	2017-09-07	ノヴォノルディスクアー／エス	医療用のｇｌｐ−１／グルカゴン受容体コアゴニスト
US9932381B2 (en)	2014-06-18	2018-04-03	Sanofi	Exendin-4 derivatives as selective glucagon receptor agonists
CN108271356A (zh)	2014-09-24	2018-07-10	印第安纳大学研究及科技有限公司	肠降血糖素-胰岛素缀合物
EP3212218B1 (de)	2014-10-29	2021-06-30	Zealand Pharma A/S	Gip-agonisten-verbindungen und -verfahren
KR102291020B1 (ko)	2014-12-30	2021-08-20	한미약품 주식회사	안정성이 증가된 글루카곤 유도체
UA121874C2 (uk)	2015-02-17	2020-08-10	Елі Ліллі Енд Компані	Порошкова назальна композиція для лікування гіпоглікемії
AR103954A1 (es)	2015-03-18	2017-06-14	Zealand Pharma As	Análogos de amilina
EP3273981B1 (de)	2015-03-24	2020-04-29	INSERM - Institut National de la Santé et de la Recherche Médicale	Verfahren und pharmazeutische zusammensetzung zur verwendung bei der behandlung von diabetes
WO2016168388A2 (en)	2015-04-14	2016-10-20	Palatin Technologies, Inc.	Therapies for obesity, diabetes and related indications
PL3283507T3 (pl)	2015-04-16	2020-05-18	Zealand Pharma A/S	Acylowany analog glukagonu
AR105319A1 (es)	2015-06-05	2017-09-27	Sanofi Sa	Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
WO2016198624A1 (en)	2015-06-12	2016-12-15	Sanofi	Exendin-4 derivatives as trigonal glp-1/glucagon/gip receptor agonists
WO2016198628A1 (en)	2015-06-12	2016-12-15	Sanofi	Non-acylated exendin-4 derivatives as dual glp-1/glucagon receptor agonists
FI3322437T3 (fi)	2015-06-30	2024-02-20	Hanmi Pharmaceutical Co Ltd	Glukagonijohdannainen ja sen pitkävaikutteisen konjugaatin käsittävä koostumus
TW201706291A (zh)	2015-07-10	2017-02-16	賽諾菲公司	作為選擇性肽雙重ｇｌｐ－１／升糖素受體促效劑之新毒蜥外泌肽（ｅｘｅｎｄｉｎ－４）衍生物
JP6712323B2 (ja)	2015-12-31	2020-06-17	ハンミファーマシューティカルカンパニーリミテッド	グルカゴン、ｇｌｐ−１及びｇｉｐ受容体のすべてに活性を有する三重活性体
GB2566228A (en) *	2016-06-09	2019-03-06	AmideBio LLC	Glucagon analogs and methods of use thereof
CN122440793A (zh) *	2016-06-29	2026-07-24	韩美药品株式会社	胰高血糖素衍生物、其缀合物、包含其的组合物、和其治疗用途
AU2017307033B2 (en)	2016-08-05	2020-11-26	Boehringer Ingelheim International Gmbh	Oxadiazolopyridine derivates for use as ghrelin O-acyl transferase (GOAT) inhibitors
AR109514A1 (es)	2016-09-09	2018-12-19	Zealand Pharma As	Análogos de amilina
AR110299A1 (es)	2016-12-02	2019-03-13	Sanofi Sa	Conjugados que comprenden un agonista dual de glp-1 / glucagón, un conector y ácido hialurónico
KR102502040B1 (ko)	2016-12-09	2023-02-24	질랜드 파마 에이/에스	아실화 glp-1/glp-2 이중 효능제
CN111655699B (zh)	2018-02-02	2023-07-14	勃林格殷格翰国际有限公司	用作饥饿素o-酰基转移酶(goat)抑制剂的杂环基取代的噁二唑并吡啶衍生物
JP7225253B2 (ja)	2018-02-02	2023-02-20	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	グレリンｏ－アシルトランスフェラーゼ（ｇｏａｔ）阻害剤として使用するためのピラゾール置換及びインダゾール置換オキサジアゾロピリジン誘導体
MX2020008053A (es)	2018-02-02	2020-09-07	Boehringer Ingelheim Int	Derivados de oxadiazolopiridina sustituidos con bencilo, (piridin-3-il)metilo o (piridin-4-il)metilo como inhibidores de ghrelin o-aciltransferasa (goat).
CA3087925A1 (en)	2018-02-02	2019-08-08	Boehringer Ingelheim International Gmbh	Triazolopyrimidine derivatives for use as ghrelin o-acyl transferase (goat) inhibitors
US20220153853A1 (en)	2018-12-21	2022-05-19	Jiangsu Hengrui Medicine Co., Ltd.	Bispecific protein
TWI771669B (zh)	2019-04-26	2022-07-21	美商美國禮來大藥廠	製備穩定胜肽調配物之方法
KR20220100925A (ko)	2019-11-11	2022-07-18	베링거 인겔하임 인터내셔날 게엠베하	Npy2 수용체 작용제
WO2021233884A1 (en)	2020-05-22	2021-11-25	Boehringer Ingelheim International Gmbh	Continuous process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate
EP4153599B1 (de)	2020-05-22	2024-03-13	Boehringer Ingelheim International GmbH	Verfahren zur herstellung von alkyl-7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-carboxylaten
WO2022029231A1 (en)	2020-08-07	2022-02-10	Boehringer Ingelheim International Gmbh	Soluble npy2 receptor agonists
JP2024516395A (ja)	2021-04-27	2024-04-15	アードバーク・セラピューティクス・インコーポレイテッド	苦味受容体アゴニストおよび腸シグナル伝達化合物の組み合わせ
GB202109087D0 (en)	2021-06-24	2021-08-11	Norwegian Univ Sci & Tech Ntnu	Therapeutic methods and devices
IL312600B2 (en)	2022-05-30	2025-12-01	Zealand Pharma As	Liquid formulations of amylin analogs

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ202757A (en)	1981-12-23	1985-11-08	Novo Industri As	Peptides and medicaments
CZ295838B6 (cs)	1996-09-09	2005-11-16	Zealand Pharma A/S	Způsob výroby peptidů
NZ504258A (en)	1997-11-14	2002-12-20	Amylin Pharmaceuticals Inc	Exendin 3 and 4 agonist compounds for the treatment of diabetes
AU757658B2 (en)	1998-03-09	2003-02-27	Zealand Pharma A/S	Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
EP1076066A1 (de)	1999-07-12	2001-02-14	Zealand Pharmaceuticals A/S	Peptide zur Senkung des Blutglukosespiegels
GB0121709D0 (en)	2001-09-07	2001-10-31	Imp College Innovations Ltd	Food inhibition agent
GB0300571D0 (en)	2003-01-10	2003-02-12	Imp College Innovations Ltd	Modification of feeding behaviour
EP1891105B1 (de) *	2005-06-13	2012-04-11	Imperial Innovations Limited	Oxyntomodulinanaloga und ihre wirkungen auf das fressverhalten
US20090202497A1 (en)	2005-08-23	2009-08-13	The General Hospital Corporation	Use of glp-1, glp-1 derivatives or glp-1 fragments for skin regeneration, stimulation of hair growth, or treatment of diabetes
NZ578948A (en)	2007-02-15	2012-03-30	Univ Indiana Res & Tech Corp	Glucagon/glp-1 receptor co-agonists
EP2025684A1 (de)	2007-08-15	2009-02-18	Zealand Pharma A/S	Glucagonanaloga

2008
- 2008-06-16 WO PCT/GB2008/002041 patent/WO2008152403A1/en not_active Ceased
- 2008-06-16 DK DK08762369.0T patent/DK2158214T3/da active
- 2008-06-16 AT AT08762369T patent/ATE520714T1/de active
- 2008-06-16 US US12/664,534 patent/US7994122B2/en not_active Expired - Fee Related
- 2008-06-16 JP JP2010511724A patent/JP5385266B2/ja not_active Expired - Fee Related
- 2008-06-16 EP EP08762369A patent/EP2158214B1/de not_active Not-in-force

Also Published As

Publication number	Publication date
DK2158214T3 (da)	2011-12-05
EP2158214B1 (de)	2011-08-17
US20100204105A1 (en)	2010-08-12
US7994122B2 (en)	2011-08-09
WO2008152403A1 (en)	2008-12-18
JP5385266B2 (ja)	2014-01-08
EP2158214A1 (de)	2010-03-03
JP2010529849A (ja)	2010-09-02

Legal Events

Date

Code

Title

Description

2012-03-15

UEP

Publication of translation of european patent specification

Ref document number: 2158214

Country of ref document: EP

Publication	Publication Date	Title
DK2158214T3 (da)	2011-12-05	Glukagonanaloger
MX2011006315A (es)	2011-09-22	Analogos de glucagon.
MX2011006320A (es)	2011-09-22	Analogos de glucagon.
TN2011000295A1 (en)	2012-12-17	Glucagon analogues
MX2011006314A (es)	2011-09-22	Analogos de glucagon.
MY188182A (en)	2021-11-24	Acylated glucagon analogues
TN2012000560A1 (en)	2014-04-01	Glucagon analogues
TN2012000567A1 (en)	2014-04-01	Glucagon analogues
WO2014041195A8 (en)	2015-02-26	Glucagon analogues
WO2015055802A3 (en)	2016-01-07	Glucagon analogues
PH12016500675A1 (en)	2016-05-30	Acylated glucagon analogues
WO2013092703A3 (en)	2013-11-14	Glucagon analogues
EP4691555A3 (de)	2026-04-22	Incretin-analoga und verwendungen davon
MX2017012864A (es)	2018-06-12	Analogo acilado del glucagon.
TN2011000667A1 (en)	2013-05-24	Acylated glucagon analogues
WO2012145281A3 (en)	2012-12-27	Methods and compositions suitable for preventing and treating hyperleptinemia
CO6382136A2 (es)	2012-02-15	Análogos de glucagón