ATE521343T1 - Im mund zerfallende zusammensetzungen von rasagilin - Google Patents

Im mund zerfallende zusammensetzungen von rasagilin

Info

Publication number
ATE521343T1
ATE521343T1 AT05851829T AT05851829T ATE521343T1 AT E521343 T1 ATE521343 T1 AT E521343T1 AT 05851829 T AT05851829 T AT 05851829T AT 05851829 T AT05851829 T AT 05851829T AT E521343 T1 ATE521343 T1 AT E521343T1
Authority
AT
Austria
Prior art keywords
rasagiline
solid pharmaceutical
provides
pharmaceutical composition
supplemental
Prior art date
Application number
AT05851829T
Other languages
English (en)
Inventor
Shulamit Patashnik
Daniella Licht
Adrian Gilbert
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Application granted granted Critical
Publication of ATE521343T1 publication Critical patent/ATE521343T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Psychology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT05851829T 2004-11-24 2005-11-17 Im mund zerfallende zusammensetzungen von rasagilin ATE521343T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63091804P 2004-11-24 2004-11-24
US99778504A 2004-11-24 2004-11-24
PCT/US2005/041882 WO2006057912A2 (en) 2004-11-24 2005-11-17 Rasagiline orally disintegrating compositions

Publications (1)

Publication Number Publication Date
ATE521343T1 true ATE521343T1 (de) 2011-09-15

Family

ID=36498434

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05851829T ATE521343T1 (de) 2004-11-24 2005-11-17 Im mund zerfallende zusammensetzungen von rasagilin

Country Status (11)

Country Link
EP (1) EP1827409B1 (de)
JP (1) JP5683769B2 (de)
CN (1) CN103494766A (de)
AT (1) ATE521343T1 (de)
AU (1) AU2005309817B2 (de)
CA (1) CA2588293C (de)
IL (1) IL183236A (de)
MX (1) MX2007006199A (de)
NZ (1) NZ555470A (de)
RU (1) RU2389482C2 (de)
WO (1) WO2006057912A2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1567152B1 (de) 2002-11-15 2013-08-14 Teva Pharmaceutical Industries Limited Verwendung von rasagilin mit riluzol zur behandlung der amyotrophenlateralsklerose
JP5004236B2 (ja) * 2005-02-09 2012-08-22 キッセイ薬品工業株式会社 口腔内崩壊錠
CA2901244A1 (en) 2005-02-23 2006-08-31 Teva Pharmaceutical Industries, Ltd. Rasagiline formulations of improved content uniformity
JP2009521402A (ja) 2005-11-17 2009-06-04 テバ ファーマシューティカル インダストリーズ リミティド プロパルギル化アミノインダンの分離のための方法
US7572834B1 (en) 2005-12-06 2009-08-11 Teva Pharmaceutical Industries, Ltd. Rasagiline formulations and processes for their preparation
EP2007369A4 (de) 2006-04-03 2009-07-01 Teva Pharma Verwendung von rasagilin zur behandlung des syndroms der ruhelosen beine
CN1911211B (zh) * 2006-08-25 2010-04-14 重庆医药工业研究院有限责任公司 雷沙吉兰口服固体制剂
BRPI0718339A2 (pt) 2006-12-14 2014-02-18 Teva Pharma Composto, composição, composição farmacêutica e processo de fabricação de tanato de rasagilina
RS52183B (sr) 2006-12-14 2012-10-31 Teva Pharmaceutical Industries, Ltd. Kristalna čvrsta baza razagilina
EP1987816A1 (de) * 2007-04-30 2008-11-05 Ratiopharm GmbH Adsorbate eines Rasagilinsalzes mit einem wasserlöslichen Hilfsstoff
EP2471516A3 (de) 2007-09-14 2012-12-26 Wockhardt Limited Rhein- oder Diacereinzusammensetzungen
EA201170181A1 (ru) 2008-07-11 2011-08-30 Синтон Бв Полиморфные формы разагилина гидрохлорида
EP2657221A1 (de) * 2008-11-20 2013-10-30 Dr. Reddy's Laboratories Ltd. Herstellung von Rasagilin und Salzen davon
DE102008064061A1 (de) * 2008-12-19 2010-06-24 Ratiopharm Gmbh Feste Zusammensetzung mit dem Wirkstoff Rasagilin
EP2218444A3 (de) 2009-01-23 2010-08-25 Teva Pharmaceutical Industries, Ltd. Rasagilinformulierung mit verzögerter Freisetzung
US20100189791A1 (en) 2009-01-23 2010-07-29 Teva Pharmaceutical Industries, Ltd. Delayed release rasagiline malate formulation
WO2010111264A2 (en) * 2009-03-24 2010-09-30 Dr. Reddy's Laboratories Ltd. Rasagiline formulations
EP2389927A1 (de) 2010-05-30 2011-11-30 Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi Pharmazeutische Formulationen von Rasagilin
EP2526924A1 (de) 2011-05-23 2012-11-28 Deva Holding Anonim Sirketi Dosis Regulierbarer oral Zerstäuber oder Aerosol Zerstäuber welches Rasagilin enthält
EP2827848B1 (de) 2012-03-21 2016-04-27 Synthon BV Stabilizierte pharmazeutische zubereitungen enthaltend salze von rasigiline
US20240115492A1 (en) 2021-01-30 2024-04-11 Intas Pharmaceuticals Ltd. An orodispersible pharmaceutical solid dosage form of rasagiline
EP4035654A1 (de) 2021-01-30 2022-08-03 Intas Pharmaceuticals Limited Schmelzbare pharmazeutische feste dosierungsform von rasagilin

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3253037A (en) * 1962-06-19 1966-05-24 Ciba Geigy Corp N-2-alkynyl-amino-benzocylo-alkanes
GB9504201D0 (en) * 1995-03-02 1995-04-19 Scherer Ltd R P Process for the preparation of a solid pharmaceutical dosage form
PL183266B1 (pl) * 1995-03-02 2002-06-28 Scherer Ltd R P Doustna kompozycja farmaceutyczna,sposób wytwarzania doustnej kompozycji farmaceutycznej oraz zastosowanie doustnej kompozycji farmaceutycznej
IL115357A (en) * 1995-09-20 2000-01-31 Teva Pharma Stable compositions containing N-propargyl-1-aminoindan and polyhydric alcohols
GB9520363D0 (en) * 1995-10-05 1995-12-06 Chiroscience Ltd Compounds
JP3709003B2 (ja) * 1996-01-26 2005-10-19 新日本製鐵株式会社 薄板連続鋳造方法
CN1469737A (zh) * 2000-10-16 2004-01-21 ��һ��������ҩ��ʽ���� 口腔内快速崩解的药用组合物及其制备方法
US7118765B2 (en) * 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
US20030175346A1 (en) * 2002-02-01 2003-09-18 Anne Billotte Osmotic delivery system
EP1778196A4 (de) * 2004-07-26 2008-12-17 Teva Pharma Pharmazeutische dosierungsformen mit rasagilin
EP1817009A2 (de) * 2004-11-24 2007-08-15 Spi Pharma, Inc. Oral zerfallende zusammensetzungen

Also Published As

Publication number Publication date
IL183236A0 (en) 2007-09-20
JP2008521808A (ja) 2008-06-26
WO2006057912A2 (en) 2006-06-01
IL183236A (en) 2014-03-31
EP1827409A2 (de) 2007-09-05
RU2389482C2 (ru) 2010-05-20
CN103494766A (zh) 2014-01-08
AU2005309817B2 (en) 2011-08-18
MX2007006199A (es) 2007-07-13
CA2588293C (en) 2013-07-02
WO2006057912A3 (en) 2006-08-17
EP1827409B1 (de) 2011-08-24
JP5683769B2 (ja) 2015-03-11
AU2005309817A1 (en) 2006-06-01
NZ555470A (en) 2011-02-25
RU2007123565A (ru) 2008-12-27
CA2588293A1 (en) 2006-06-01
EP1827409A4 (de) 2008-03-19
HK1101804A1 (en) 2007-10-26

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