ATE521710T1 - Chemisch induzierbare expression von biosynthesewegen - Google Patents
Chemisch induzierbare expression von biosynthesewegenInfo
- Publication number
- ATE521710T1 ATE521710T1 AT06738572T AT06738572T ATE521710T1 AT E521710 T1 ATE521710 T1 AT E521710T1 AT 06738572 T AT06738572 T AT 06738572T AT 06738572 T AT06738572 T AT 06738572T AT E521710 T1 ATE521710 T1 AT E521710T1
- Authority
- AT
- Austria
- Prior art keywords
- enzyme
- constructs
- enzymes
- transgenes
- transgene
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 230000037361 pathway Effects 0.000 title 1
- 108700019146 Transgenes Proteins 0.000 abstract 7
- 108090000790 Enzymes Proteins 0.000 abstract 5
- 102000004190 Enzymes Human genes 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 239000012190 activator Substances 0.000 abstract 4
- 230000001939 inductive effect Effects 0.000 abstract 4
- 230000006696 biosynthetic metabolic pathway Effects 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 230000001851 biosynthetic effect Effects 0.000 abstract 1
- 230000008488 polyadenylation Effects 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8237—Externally regulated expression systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Nutrition Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66223505P | 2005-03-16 | 2005-03-16 | |
| US66976605P | 2005-04-08 | 2005-04-08 | |
| PCT/US2006/009531 WO2006101983A2 (en) | 2005-03-16 | 2006-03-16 | Chemically inducible expression of biosynthetic pathways |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE521710T1 true ATE521710T1 (de) | 2011-09-15 |
Family
ID=36778209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06738572T ATE521710T1 (de) | 2005-03-16 | 2006-03-16 | Chemisch induzierbare expression von biosynthesewegen |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7732680B2 (de) |
| EP (1) | EP1863916B1 (de) |
| JP (1) | JP2008532553A (de) |
| AT (1) | ATE521710T1 (de) |
| AU (1) | AU2006227634B2 (de) |
| BR (1) | BRPI0608637A2 (de) |
| CA (2) | CA2600882C (de) |
| WO (1) | WO2006101983A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2600882C (en) * | 2005-03-16 | 2013-02-26 | Metabolix, Inc. | Chemically inducible expression of biosynthetic pathways |
| US8487159B2 (en) * | 2008-04-28 | 2013-07-16 | Metabolix, Inc. | Production of polyhydroxybutyrate in switchgrass |
| WO2010025374A2 (en) * | 2008-08-29 | 2010-03-04 | E. I. Du Pont De Nemours And Company | Manipulation of snf1 protein kinase activity for altered oil content in oleaginous organisms |
| US20100055671A1 (en) * | 2008-09-03 | 2010-03-04 | National Tsing Hua University | Method for Determining Transduction Efficiency and Virus Dosage of Baculovirus |
| WO2010057271A1 (en) * | 2008-11-21 | 2010-05-27 | Sugar Industry Innovation Pty Ltd | Polyhydroxyalkanoate production in plant peroxisomes |
| WO2011034945A1 (en) | 2009-09-15 | 2011-03-24 | Metabolix, Inc. | Generation of high polyhydroxybutrate producing oilseeds |
| KR101719776B1 (ko) | 2014-11-13 | 2017-04-10 | 대한민국 | 지방산 대사 관여 유전자의 고발현을 유도하는 프로모터 및 이의 용도 |
| US10533192B2 (en) | 2015-12-22 | 2020-01-14 | Nutech Ventures | Production of isoprene by methane-producing archaea |
| CN116875524B (zh) * | 2023-09-08 | 2024-03-26 | 清华大学 | 一种在微生物中调控多基因表达的方法及其应用 |
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| US5352605A (en) | 1983-01-17 | 1994-10-04 | Monsanto Company | Chimeric genes for transforming plant cells using viral promoters |
| US5034322A (en) | 1983-01-17 | 1991-07-23 | Monsanto Company | Chimeric genes suitable for expression in plant cells |
| US5231019A (en) | 1984-05-11 | 1993-07-27 | Ciba-Geigy Corporation | Transformation of hereditary material of plants |
| US5668298A (en) | 1984-12-24 | 1997-09-16 | Eli Lilly And Company | Selectable marker for development of vectors and transformation systems in plants |
| US5024944A (en) | 1986-08-04 | 1991-06-18 | Lubrizol Genetics, Inc. | Transformation, somatic embryogenesis and whole plant regeneration method for Glycine species |
| US5276268A (en) | 1986-08-23 | 1994-01-04 | Hoechst Aktiengesellschaft | Phosphinothricin-resistance gene, and its use |
| US5268463A (en) | 1986-11-11 | 1993-12-07 | Jefferson Richard A | Plant promoter α-glucuronidase gene construct |
| US5004863B2 (en) | 1986-12-03 | 2000-10-17 | Agracetus | Genetic engineering of cotton plants and lines |
| US5015580A (en) | 1987-07-29 | 1991-05-14 | Agracetus | Particle-mediated transformation of soybean plants and lines |
| US5015944A (en) | 1986-12-10 | 1991-05-14 | Bubash James E | Current indicating device |
| US5030572A (en) | 1987-04-01 | 1991-07-09 | Lubrizol Genetics, Inc. | Sunflower regeneration from cotyledons |
| US5245023A (en) | 1987-06-29 | 1993-09-14 | Massachusetts Institute Of Technology | Method for producing novel polyester biopolymers |
| US4876331A (en) | 1987-08-18 | 1989-10-24 | Mitsubishi Kasei Corporation | Copolyester and process for producing the same |
| KR0154872B1 (ko) | 1987-12-21 | 1998-10-15 | 로버트 에이. 아미테이지 | 발아하는 식물종자의 아크로박테리움 매개된 형질전환 |
| FR2627508B1 (fr) | 1988-02-22 | 1990-10-05 | Eurolysine | Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede |
| US5416011A (en) | 1988-07-22 | 1995-05-16 | Monsanto Company | Method for soybean transformation and regeneration |
| US5000000A (en) | 1988-08-31 | 1991-03-19 | University Of Florida | Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes |
| US5629183A (en) | 1989-05-08 | 1997-05-13 | The United States Of America As Represented By The Secretary Of Agriculture | Plant transformation by gene transfer into pollen |
| US5102797A (en) | 1989-05-26 | 1992-04-07 | Dna Plant Technology Corporation | Introduction of heterologous genes into bacteria using transposon flanked expression cassette and a binary vector system |
| US5371002A (en) | 1989-06-07 | 1994-12-06 | James Madison University | Method of production of poly-beta-hydroxyalkanoate copolymers |
| US5302523A (en) | 1989-06-21 | 1994-04-12 | Zeneca Limited | Transformation of plant cells |
| ATE172497T1 (de) | 1989-07-10 | 1998-11-15 | Massachusetts Inst Technology | Verfahren zur herstellung von polyester- biopolymeren |
| US5322783A (en) | 1989-10-17 | 1994-06-21 | Pioneer Hi-Bred International, Inc. | Soybean transformation by microparticle bombardment |
| US5484956A (en) | 1990-01-22 | 1996-01-16 | Dekalb Genetics Corporation | Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin |
| US5519164A (en) | 1990-02-01 | 1996-05-21 | Hoechst Aktiengesellschaft | Expression of a multigene RNA having self-splicing activity |
| US5512456A (en) | 1990-05-25 | 1996-04-30 | James Madison University | Method for the improved production and recovery of poly-β-hydroxybutyrate from transformed Escherichia coli |
| NZ239977A (en) | 1990-11-14 | 1993-08-26 | Pioneer Hi Bred Int | Transforming plants by the use of agrobacterium |
| US5384253A (en) | 1990-12-28 | 1995-01-24 | Dekalb Genetics Corporation | Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes |
| DK152291D0 (da) | 1991-08-28 | 1991-08-28 | Danisco | Fremgangsmaade og kemiske forbindelser |
| GB9304200D0 (en) | 1993-03-02 | 1993-04-21 | Sandoz Ltd | Improvements in or relating to organic compounds |
| JP2777757B2 (ja) | 1991-09-17 | 1998-07-23 | 鐘淵化学工業株式会社 | 共重合体およびその製造方法 |
| US5569595A (en) | 1991-09-27 | 1996-10-29 | Center For Innovative Technology | Production of poly-β-hydroxybutyrate in prokaryotic host cells |
| PT637339E (pt) * | 1992-04-13 | 2002-03-28 | Syngenta Ltd | Construcoes de adn e plantas que as incorporam |
| ATE398679T1 (de) | 1992-07-07 | 2008-07-15 | Japan Tobacco Inc | Verfahren zur transformation einer monokotyledon pflanze |
| US5527695A (en) | 1993-01-29 | 1996-06-18 | Purdue Research Foundation | Controlled modification of eukaryotic genomes |
| US5470727A (en) | 1993-12-21 | 1995-11-28 | Celtrix Pharmaceuticals, Inc. | Chromosomal expression of non-bacterial genes in bacterial cells |
| US5545818A (en) | 1994-03-11 | 1996-08-13 | Calgene Inc. | Expression of Bacillus thuringiensis cry proteins in plant plastids |
| EP2311959B1 (de) | 1994-08-31 | 2015-08-12 | E. I. du Pont de Nemours and Company | Nukleotidsequenzen von Raps-Palmitoyl-ACP-Thioesterasegenen und ihre Verwendung zur Regulierung des Fettsäuregehalts von Ölen aus Sojabohnen und Rapspflanzen |
| DE4433134A1 (de) | 1994-09-16 | 1996-03-21 | Buck Chem Tech Werke | Verfahren zur Herstellung von Polyhydroxyfettsäuren sowie rekombinanter Bakterienstämme zur Durchführung des Verfahrens |
| US5801026A (en) | 1994-09-26 | 1998-09-01 | Carnegie Institution Of Washington | Use of plant fatty acyl hydroxylases to produce hydroxylated fatty acids and derivatives in plants |
| IL116872A (en) * | 1995-02-15 | 2004-12-15 | Aventis Pharma Sa | Delta-5, 7 sterol reductase from arabidopsis thaliana |
| US5849894A (en) | 1995-11-29 | 1998-12-15 | Monsanto Company | Rhodospirillum rubrum poly-β-hydroxyalkanoate synthase |
| US5958745A (en) | 1996-03-13 | 1999-09-28 | Monsanto Company | Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants |
| US5811272A (en) | 1996-07-26 | 1998-09-22 | Massachusetts Institute Of Technology | Method for controlling molecular weight of polyhydroxyalkanoates |
| US5750848A (en) | 1996-08-13 | 1998-05-12 | Monsanto Company | DNA sequence useful for the production of polyhydroxyalkanoates |
| US6051754A (en) | 1997-04-11 | 2000-04-18 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants |
| BR9809946A (pt) | 1997-06-04 | 2000-08-01 | Calgene Llc | Produção de ácidos graxos poliinsaturados por expressão de genes de sìntese semelhantes a policetìdeo em plantas |
| EP1015565B1 (de) | 1997-09-19 | 2006-04-12 | Metabolix, Inc. | Biologische systeme zur herstellung von polyhydroxyalkanoate polymeren die 4-hydroxysäure enthalten |
| US6586658B1 (en) | 1998-03-06 | 2003-07-01 | Metabolix, Inc. | Modification of fatty acid metabolism in plants |
| ATE317014T1 (de) | 1998-07-30 | 2006-02-15 | Metabolix Inc | Bifunktionelle enzyme zur biopolymerherstellung |
| US6329183B1 (en) | 1998-08-04 | 2001-12-11 | Metabolix, Inc. | Polyhydroxyalkanoate production from polyols |
| ATE319835T1 (de) | 1998-08-18 | 2006-03-15 | Metabolix Inc | Transgene polyhydroxyalkanoat produzierende mikroben |
| KR20020013463A (ko) * | 1998-08-18 | 2002-02-20 | 와일러 제임스 에프. | 유전자의 발현을 증강시키고 제한하는 방법 |
| US6835820B2 (en) | 1999-01-07 | 2004-12-28 | The University Of Massachusetts | Polyhydroxyalkanoate biosynthesis associated proteins and coding region in bacillus megaterium |
| AU3516100A (en) * | 1999-03-05 | 2000-09-21 | Monsanto Technology Llc | Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways |
| WO2000078985A1 (en) * | 1999-06-24 | 2000-12-28 | Metabolix, Inc. | Plant multi-gene expression constructs |
| AU779239C (en) * | 1999-10-19 | 2006-04-06 | Minos Biosystems Limited | Protein production system |
| AU1453501A (en) * | 1999-11-10 | 2001-06-06 | Genzyme Corporation | Ptp/dna polymerase cell line as packaging cell line for minimal adenoviral vectors |
| AU2001236839A1 (en) * | 2000-02-11 | 2001-08-20 | Metabolix, Inc. | Multi-gene expression constructs containing modified inteins |
| GB0025217D0 (en) * | 2000-10-14 | 2000-11-29 | Cambridge Advanced Tech | Plant cell death system |
| AUPR143100A0 (en) | 2000-11-10 | 2000-12-07 | Bureau Of Sugar Experiment Stations | Plant transformation |
| AU3646402A (en) * | 2000-11-17 | 2002-05-27 | Metabolix Inc | Production of medium chain length polyhydroxyalkanoates from fatty acid biosynthetic pathways |
| DE10102338A1 (de) * | 2001-01-19 | 2002-07-25 | Basf Plant Science Gmbh | Verfahren zur Expression von Biosynthesegenen in pflanzlichen Samen unter Verwendung von neuen multiplen Expressionskonstrukten |
| US6635451B2 (en) | 2001-01-25 | 2003-10-21 | Abbott Laboratories | Desaturase genes and uses thereof |
| US20040172682A1 (en) | 2003-02-12 | 2004-09-02 | Kinney Anthony J. | Production of very long chain polyunsaturated fatty acids in oilseed plants |
| CA2600882C (en) * | 2005-03-16 | 2013-02-26 | Metabolix, Inc. | Chemically inducible expression of biosynthetic pathways |
-
2006
- 2006-03-16 CA CA2600882A patent/CA2600882C/en not_active Expired - Fee Related
- 2006-03-16 JP JP2008502042A patent/JP2008532553A/ja active Pending
- 2006-03-16 AT AT06738572T patent/ATE521710T1/de not_active IP Right Cessation
- 2006-03-16 EP EP06738572A patent/EP1863916B1/de not_active Expired - Lifetime
- 2006-03-16 AU AU2006227634A patent/AU2006227634B2/en not_active Ceased
- 2006-03-16 CA CA2800359A patent/CA2800359A1/en not_active Abandoned
- 2006-03-16 US US11/376,831 patent/US7732680B2/en not_active Expired - Fee Related
- 2006-03-16 BR BRPI0608637-3A patent/BRPI0608637A2/pt not_active IP Right Cessation
- 2006-03-16 WO PCT/US2006/009531 patent/WO2006101983A2/en not_active Ceased
-
2010
- 2010-04-19 US US12/762,941 patent/US8742203B2/en not_active Expired - Fee Related
-
2012
- 2012-08-21 US US13/590,933 patent/US20130042371A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006101983A3 (en) | 2007-02-15 |
| US20070067869A1 (en) | 2007-03-22 |
| AU2006227634B2 (en) | 2010-07-08 |
| US8742203B2 (en) | 2014-06-03 |
| US20100196974A1 (en) | 2010-08-05 |
| AU2006227634A1 (en) | 2006-09-28 |
| JP2008532553A (ja) | 2008-08-21 |
| WO2006101983A2 (en) | 2006-09-28 |
| US20130042371A1 (en) | 2013-02-14 |
| EP1863916A2 (de) | 2007-12-12 |
| CA2800359A1 (en) | 2006-09-28 |
| CA2600882A1 (en) | 2006-09-28 |
| BRPI0608637A2 (pt) | 2010-01-19 |
| CA2600882C (en) | 2013-02-26 |
| US7732680B2 (en) | 2010-06-08 |
| EP1863916B1 (de) | 2011-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |