ATE524177T1 - Verwendung eines kinasehemmers zur behandlung von bestimmten resistenten tumoren - Google Patents

Verwendung eines kinasehemmers zur behandlung von bestimmten resistenten tumoren

Info

Publication number
ATE524177T1
ATE524177T1 AT07727485T AT07727485T ATE524177T1 AT E524177 T1 ATE524177 T1 AT E524177T1 AT 07727485 T AT07727485 T AT 07727485T AT 07727485 T AT07727485 T AT 07727485T AT E524177 T1 ATE524177 T1 AT E524177T1
Authority
AT
Austria
Prior art keywords
abl
compounds
resistant
atp
kinase
Prior art date
Application number
AT07727485T
Other languages
English (en)
Inventor
Daniele Fancelli
Antonella Isacchi
Michele Modugno
Jurgen Moll
Luisa Rusconi
Chiara Soncini
Rosita Lupi
Original Assignee
Nerviano Medical Sciences Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nerviano Medical Sciences Srl filed Critical Nerviano Medical Sciences Srl
Application granted granted Critical
Publication of ATE524177T1 publication Critical patent/ATE524177T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT07727485T 2006-03-30 2007-03-29 Verwendung eines kinasehemmers zur behandlung von bestimmten resistenten tumoren ATE524177T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06112026 2006-03-30
PCT/EP2007/053013 WO2007113198A2 (en) 2006-03-30 2007-03-29 Use of a kinase inhibitor for the treatment of particular resistant tumors

Publications (1)

Publication Number Publication Date
ATE524177T1 true ATE524177T1 (de) 2011-09-15

Family

ID=38180687

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07727485T ATE524177T1 (de) 2006-03-30 2007-03-29 Verwendung eines kinasehemmers zur behandlung von bestimmten resistenten tumoren

Country Status (5)

Country Link
US (1) US7803829B2 (de)
EP (1) EP2007380B1 (de)
JP (1) JP2009534307A (de)
AT (1) ATE524177T1 (de)
WO (1) WO2007113198A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110945002B (zh) * 2017-08-01 2021-12-24 正大天晴药业集团股份有限公司 作为RORγ抑制剂的双环化合物
CN108399315B (zh) * 2018-03-01 2022-02-22 中国科学院长春应用化学研究所 一种Bcr-Abl蛋白激酶抑制剂的筛选方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003047523A2 (en) * 2001-12-04 2003-06-12 Onyx Pharmaceuticals, Inc. Raf-mek-erk pathway inhibitors to treat cancer
BR0312722A (pt) 2002-07-17 2005-05-10 Pharmacia Italia Spa Derivados de pirazol heterobicìclico como inibidores de qinase
TW200526204A (en) * 2004-02-03 2005-08-16 Pharmacia Italia Spa 1h-thieno[2,3-c]pyrazole derivatives useful as kinase inhibitors

Also Published As

Publication number Publication date
EP2007380A2 (de) 2008-12-31
JP2009534307A (ja) 2009-09-24
WO2007113198A2 (en) 2007-10-11
US7803829B2 (en) 2010-09-28
US20100022532A1 (en) 2010-01-28
EP2007380B1 (de) 2011-09-14
WO2007113198A3 (en) 2008-03-20

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Legal Events

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