ATE524557T1 - Verbreiteter polymorphismus in scn5a, einhergehend mit durch medikamente induzierte herzarrythmien - Google Patents

Verbreiteter polymorphismus in scn5a, einhergehend mit durch medikamente induzierte herzarrythmien

Info

Publication number
ATE524557T1
ATE524557T1 AT01954751T AT01954751T ATE524557T1 AT E524557 T1 ATE524557 T1 AT E524557T1 AT 01954751 T AT01954751 T AT 01954751T AT 01954751 T AT01954751 T AT 01954751T AT E524557 T1 ATE524557 T1 AT E524557T1
Authority
AT
Austria
Prior art keywords
drug
scn5a
pointes
ventricular fibrillation
torsade
Prior art date
Application number
AT01954751T
Other languages
English (en)
Inventor
Mark Keating
Igor Splawski
Original Assignee
Univ Utah Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22820569&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE524557(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Utah Res Found filed Critical Univ Utah Res Found
Application granted granted Critical
Publication of ATE524557T1 publication Critical patent/ATE524557T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT01954751T 2000-07-20 2001-07-19 Verbreiteter polymorphismus in scn5a, einhergehend mit durch medikamente induzierte herzarrythmien ATE524557T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21973800P 2000-07-20 2000-07-20
PCT/US2001/022639 WO2002008381A2 (en) 2000-07-20 2001-07-19 Common polymorphism in scn5a implicated in drug-induced cardiac arrhythmia

Publications (1)

Publication Number Publication Date
ATE524557T1 true ATE524557T1 (de) 2011-09-15

Family

ID=22820569

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01954751T ATE524557T1 (de) 2000-07-20 2001-07-19 Verbreiteter polymorphismus in scn5a, einhergehend mit durch medikamente induzierte herzarrythmien

Country Status (7)

Country Link
US (1) US7208273B2 (de)
EP (1) EP1349955B1 (de)
JP (1) JP2004504054A (de)
AT (1) ATE524557T1 (de)
AU (1) AU2001276976A1 (de)
CA (1) CA2416545C (de)
WO (1) WO2002008381A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003286340A1 (en) * 2002-12-21 2004-07-14 Pfizer Products Inc. Methods and compositions relating to drug-induced arrhythmia
CA2554836A1 (en) * 2004-02-05 2005-08-25 Medtronic, Inc. Methods and apparatus for identifying patients at risk for life threatening arrhythmias
US7608458B2 (en) * 2004-02-05 2009-10-27 Medtronic, Inc. Identifying patients at risk for life threatening arrhythmias
US8335652B2 (en) * 2004-06-23 2012-12-18 Yougene Corp. Self-improving identification method
US8027791B2 (en) * 2004-06-23 2011-09-27 Medtronic, Inc. Self-improving classification system
US20050287574A1 (en) * 2004-06-23 2005-12-29 Medtronic, Inc. Genetic diagnostic method for SCD risk stratification
US7396524B2 (en) * 2005-08-02 2008-07-08 Main Line Health Heart Center Methods for screening compounds for proarrhythmic risk and antiarrhythmic efficacy
US20110143956A1 (en) * 2007-11-14 2011-06-16 Medtronic, Inc. Diagnostic Kits and Methods for SCD or SCA Therapy Selection
EP2222877A4 (de) * 2007-11-14 2011-10-12 Medtronic Inc Genetische marker für die scd- oder sca-therapieauswahl
US7874664B2 (en) * 2008-07-23 2011-01-25 Xerox Corporation Electrically conductive pressure roll surfaces for phase-change ink-jet printer for direct on paper printing
US7845783B2 (en) 2008-07-23 2010-12-07 Xerox Corporation Pressure roller two-layer coating for phase-change ink-jet printer for direct on paper printing
US7810922B2 (en) * 2008-07-23 2010-10-12 Xerox Corporation Phase change ink imaging component having conductive coating
US7896488B2 (en) * 2008-07-23 2011-03-01 Xerox Corporation Phase change ink imaging component having two-layer configuration
EP2430184A2 (de) * 2009-05-12 2012-03-21 Medtronic, Inc. Sca-risikostratifizierung durch vorhersage des ansprechens von patienten auf antiarrhythmika
WO2011053134A2 (en) * 2009-10-26 2011-05-05 Academisch Medisch Centrum Bij De Universiteit Van Amsterdam Determination of genetic risk for ventricular fibrillation
EP2548018A4 (de) * 2010-03-19 2013-08-07 Cardio Dx Inc Bestimmung der empfindlichkeit für plötzliche kardiale ereignisse
US20110237456A1 (en) * 2010-03-24 2011-09-29 Aris Floratos Biomarkers for drug-induced elongated qt interval and torsades de pointes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996028537A1 (en) 1995-03-09 1996-09-19 University Of Utah Research Foundation Long qt genes and method for diagnosing or preventing the occurrence of long qt syndrome
US5599673A (en) * 1995-03-09 1997-02-04 University Of Utah Research Foundation Long QT syndrome genes

Also Published As

Publication number Publication date
CA2416545C (en) 2012-11-27
EP1349955B1 (de) 2011-09-14
CA2416545A1 (en) 2002-01-31
WO2002008381A3 (en) 2003-08-07
AU2001276976A1 (en) 2002-02-05
US20030235838A1 (en) 2003-12-25
US7208273B2 (en) 2007-04-24
EP1349955A2 (de) 2003-10-08
JP2004504054A (ja) 2004-02-12
WO2002008381A2 (en) 2002-01-31

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