ATE525359T1 - Modulatoren der aktivität des glucokortikoidrezeptors von ap-1 und/oder von nf- kb und anwendung davon - Google Patents

Modulatoren der aktivität des glucokortikoidrezeptors von ap-1 und/oder von nf- kb und anwendung davon

Info

Publication number: ATE525359T1
Authority: AT; Austria
Prior art keywords: glucocorticoid receptor; modulators; application; receptor activity; diseases
Prior art date: 2005-06-14

Application number

AT06773159T

Other languages

English (en)

Inventor

Jingwu Duan

Zhonghui Lu

David Weinstein

Bin Jiang

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-06-14

Filing date

2006-06-14

Publication date

2011-10-15

2006-06-14 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2011-10-15 Application granted granted Critical

2011-10-15 Publication of ATE525359T1 publication Critical patent/ATE525359T1/de

Links

102000003676 Glucocorticoid Receptors Human genes 0.000 title abstract 2
108090000079 Glucocorticoid Receptors Proteins 0.000 title abstract 2
102000003945 NF-kappa B Human genes 0.000 title abstract 2
108010057466 NF-kappa B Proteins 0.000 title abstract 2
230000000694 effects Effects 0.000 title abstract 2
208000008589 Obesity Diseases 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
206010012601 diabetes mellitus Diseases 0.000 abstract 2
201000010099 disease Diseases 0.000 abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
230000002757 inflammatory effect Effects 0.000 abstract 2
235000020824 obesity Nutrition 0.000 abstract 2
208000026278 immune system disease Diseases 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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Health & Medical Sciences (AREA)
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AT06773159T 2005-06-14 2006-06-14 Modulatoren der aktivität des glucokortikoidrezeptors von ap-1 und/oder von nf- kb und anwendung davon ATE525359T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US69035505P	2005-06-14	2005-06-14
US78263606P	2006-03-15	2006-03-15
US11/451,660 US7888381B2 (en)	2005-06-14	2006-06-13	Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity, and use thereof
PCT/US2006/023164 WO2006138373A2 (en)	2005-06-14	2006-06-14	MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF

Publications (1)

Publication Number	Publication Date
ATE525359T1 true ATE525359T1 (de)	2011-10-15

Family

ID=37401459

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AT06773159T ATE525359T1 (de)	2005-06-14	2006-06-14	Modulatoren der aktivität des glucokortikoidrezeptors von ap-1 und/oder von nf- kb und anwendung davon

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US (1)	US7888381B2 (de)
EP (1)	EP1896424B1 (de)
JP (1)	JP2008546702A (de)
AT (1)	ATE525359T1 (de)
WO (1)	WO2006138373A2 (de)

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2006
- 2006-06-13 US US11/451,660 patent/US7888381B2/en active Active
- 2006-06-14 WO PCT/US2006/023164 patent/WO2006138373A2/en not_active Ceased
- 2006-06-14 AT AT06773159T patent/ATE525359T1/de not_active IP Right Cessation
- 2006-06-14 EP EP06773159A patent/EP1896424B1/de not_active Not-in-force
- 2006-06-14 JP JP2008517065A patent/JP2008546702A/ja not_active Ceased

Also Published As

Publication number	Publication date
EP1896424B1 (de)	2011-09-21
US7888381B2 (en)	2011-02-15
US20070129400A1 (en)	2007-06-07
WO2006138373A2 (en)	2006-12-28
WO2006138373A3 (en)	2007-05-10
EP1896424A2 (de)	2008-03-12
JP2008546702A (ja)	2008-12-25

Legal Events

Date	Code	Title	Description
2012-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE525359T1 (de)	2011-10-15	Modulatoren der aktivität des glucokortikoidrezeptors von ap-1 und/oder von nf- kb und anwendung davon
SE0401971D0 (sv)	2004-08-02	Piperidne derivatives
EA200602241A1 (ru)	2007-04-27	Замещённые индазолы, композиции, содержащие указанные индазолы, способ их получения и применение
EA200800172A1 (ru)	2008-08-29	2,4-диаминопиримидины как ингибиторы aurora
SE0401342D0 (sv)	2004-05-25	Therapeutic compounds
TW200615266A (en)	2006-05-16	Organic compounds
PA8720801A1 (es)	2008-11-19	Nuevas combinaciones terapeuticas para el tratamiento de la depresion
EA200700489A1 (ru)	2007-10-26	Новые бензоконденсированные гетероарилсульфамидные производные, полезные в качестве противоконвульсивных средств
ATE449604T1 (de)	2009-12-15	Pyrazolamid-derivate, diese verbindungen enthaltende zusammensetzungen und anwendungsverfahren
SE0401345D0 (sv)	2004-05-25	Therapeutic compounds: Pyridine as scaffold
SE0401762D0 (sv)	2004-07-05	Novel compounds
SE0401970D0 (sv)	2004-08-02	Novel compounds
SE0303541D0 (sv)	2003-12-22	New compounds
ATE499349T1 (de)	2011-03-15	Substituierte heteroarylamidmodulatoren der aktivität des glucokortikoidrezeptors, von ap-1 und/oder von nfkb und anwendung davon
MY145647A (en)	2012-03-15	(4-hydroxy-2-oxo-3h-benzothiazol-7-yl)ethylamine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy (for example in the treatment of respiratory disease states)
ATE441632T1 (de)	2009-09-15	Gesättigte und ungesättigte 3-pyridyl- benzocycloalkylmethyl-amine zur behandlung von schmerzen, depressionen und angstzuständen
ATE546452T1 (de)	2012-03-15	Pyrazolopyrrolderivate als proteinkinaseinhibitoren
ATE466841T1 (de)	2010-05-15	1-phenethylpiperidinderivate und ihre verwendung als opioidrezeptor-liganden
UY29370A1 (es)	2006-10-02	Derivados de tiazol, composiciones que lo contienen, procedimientos de preparación y aplicaciones
ATE546439T1 (de)	2012-03-15	Heterocyclische modulatoren der glucocorticoidrezeptor-, ap-1- und/oder nf-kb- aktivität und deren verwendung
MX2007007027A (es)	2007-07-04	Derivados piperazinilpiridina como agentes anti-obesidad.
TW200626581A (en)	2006-08-01	Compounds, compositions containing them, preparation thereof and uses thereof
EA200870223A1 (ru)	2009-02-27	Производные бензоизоиндола для лечения боли
DK1853232T3 (da)	2009-12-14	Stabil krystallin form af bifeprunox mesylat, doseringsformer deraf og fremgangsmåder for deres anvendelse
ATE482959T1 (de)	2010-10-15	Heteroarylsubstituierte diazatricycloalkane, verfahren zu deren herstellung und deren anwendung