ATE525371T1 - Salze von imidazol-5-carbonsäure-derivaten, herstellungsverfahren und verwendung davon - Google Patents

Salze von imidazol-5-carbonsäure-derivaten, herstellungsverfahren und verwendung davon

Info

Publication number
ATE525371T1
ATE525371T1 AT06828254T AT06828254T ATE525371T1 AT E525371 T1 ATE525371 T1 AT E525371T1 AT 06828254 T AT06828254 T AT 06828254T AT 06828254 T AT06828254 T AT 06828254T AT E525371 T1 ATE525371 T1 AT E525371T1
Authority
AT
Austria
Prior art keywords
imidazole
salts
acid derivatives
production
carbonic acid
Prior art date
Application number
AT06828254T
Other languages
English (en)
Inventor
Jianhui Guo
Dong An
Original Assignee
Shanghai Allist Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Allist Pharmaceutical Inc filed Critical Shanghai Allist Pharmaceutical Inc
Application granted granted Critical
Publication of ATE525371T1 publication Critical patent/ATE525371T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT06828254T 2006-12-06 2006-12-06 Salze von imidazol-5-carbonsäure-derivaten, herstellungsverfahren und verwendung davon ATE525371T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2006/003301 WO2008067687A1 (en) 2006-12-06 2006-12-06 The salts of imidazol-5-carboxylic acid derivatives, preparation methods and use therrof

Publications (1)

Publication Number Publication Date
ATE525371T1 true ATE525371T1 (de) 2011-10-15

Family

ID=39491635

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06828254T ATE525371T1 (de) 2006-12-06 2006-12-06 Salze von imidazol-5-carbonsäure-derivaten, herstellungsverfahren und verwendung davon

Country Status (8)

Country Link
US (1) US7943648B2 (de)
EP (1) EP2103610B1 (de)
JP (1) JP5290190B2 (de)
KR (1) KR101112515B1 (de)
AT (1) ATE525371T1 (de)
AU (1) AU2006351517B8 (de)
CA (1) CA2671816C (de)
WO (1) WO2008067687A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101024643A (zh) 2006-02-20 2007-08-29 上海艾力斯医药科技有限公司 咪唑－5－羧酸类衍生物、制备方法及其应用
CN101214242A (zh) * 2007-01-05 2008-07-09 上海艾力斯医药科技有限公司 新的药用组合物
CN101317842A (zh) * 2007-06-07 2008-12-10 上海艾力斯医药科技有限公司 一种咪唑-5-羧酸衍生物的治疗用途
CN101407511B (zh) 2007-10-11 2013-01-09 上海艾力斯生物医药有限公司 一种结晶型的咪唑-5-羧酸衍生物
CN101596189A (zh) * 2008-06-05 2009-12-09 上海艾力斯生物医药有限公司 含有咪唑-5-羧酸类衍生物的药用组合物
CN102648185A (zh) * 2009-10-26 2012-08-22 莱西肯医药有限公司 制备1-(4-((1r，2s，3r)-1，2，3，4-四羟基丁基)-1h-咪唑-2-基)乙酮的方法
WO2012039447A1 (ja) * 2010-09-24 2012-03-29 第一三共株式会社 置換シクロアルケン誘導体の結晶
CN106188012B (zh) * 2014-06-20 2018-11-30 深圳信立泰药业股份有限公司 一种阿利沙坦酯结晶及其制备方法及含有该结晶的药物组合物
KR20230024766A (ko) 2021-08-12 2023-02-21 현대모비스 주식회사 디스플레이 및 이를 포함하는 차량의 칵핏 모듈

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138069A (en) 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
CA1334092C (en) 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
US5196444A (en) 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
US5616599A (en) 1991-02-21 1997-04-01 Sankyo Company, Limited Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use
AT398202B (de) * 1991-10-04 1994-10-25 Chem Pharm Forsch Gmbh Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung
US5310929A (en) * 1992-08-06 1994-05-10 E. I. Du Pont De Nemours And Company Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists
RU2374240C2 (ru) * 2003-07-31 2009-11-27 Никокс С.А. Нитрооксипроизводные лозартана, валсартана, кандесартана, телмисартана, эпросартана и олмесартана в качестве блокаторов рецепторов ангиотензина ii для лечения сердечно-сосудистых заболеваний
US20070238740A1 (en) * 2003-08-28 2007-10-11 Nitromed, Inc. Nitrosated And Nitrosylated Cardiovascular Compounds, Compositions And Methods Of Use
DE602006010364D1 (de) * 2005-04-22 2009-12-24 Daiichi Sankyo Co Ltd Pharmazeutikum zur prävention oder behandlung von metabolischer knochenkrankheit
CN101024643A (zh) * 2006-02-20 2007-08-29 上海艾力斯医药科技有限公司 咪唑－5－羧酸类衍生物、制备方法及其应用
CN101195615B (zh) * 2006-12-06 2013-03-27 深圳市信立泰资产管理有限公司 咪唑-5-羧酸衍生物的盐、制备方法及其药物组合物

Also Published As

Publication number Publication date
US7943648B2 (en) 2011-05-17
KR101112515B1 (ko) 2012-02-24
AU2006351517B2 (en) 2011-12-22
JP2010511636A (ja) 2010-04-15
AU2006351517B8 (en) 2012-01-19
US20090326024A1 (en) 2009-12-31
CA2671816C (en) 2012-06-05
WO2008067687A1 (en) 2008-06-12
JP5290190B2 (ja) 2013-09-18
EP2103610A1 (de) 2009-09-23
KR20100004917A (ko) 2010-01-13
EP2103610B1 (de) 2011-09-21
EP2103610A4 (de) 2011-01-05
CA2671816A1 (en) 2008-06-12
AU2006351517A1 (en) 2008-06-12

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