ATE525655T1 - Nanostrukturen zur polarisierten abbildung und rezeptor-/liganden-quantifizierung: überschreitung der diffraktionsgrenze für abbildungen - Google Patents
Nanostrukturen zur polarisierten abbildung und rezeptor-/liganden-quantifizierung: überschreitung der diffraktionsgrenze für abbildungenInfo
- Publication number
- ATE525655T1 ATE525655T1 AT06851637T AT06851637T ATE525655T1 AT E525655 T1 ATE525655 T1 AT E525655T1 AT 06851637 T AT06851637 T AT 06851637T AT 06851637 T AT06851637 T AT 06851637T AT E525655 T1 ATE525655 T1 AT E525655T1
- Authority
- AT
- Austria
- Prior art keywords
- imaging
- nanostructures
- receptor
- exceeding
- polarized
- Prior art date
Links
- 239000002086 nanomaterial Substances 0.000 title abstract 5
- 238000003384 imaging method Methods 0.000 title 2
- 239000003446 ligand Substances 0.000 title 1
- 238000011002 quantification Methods 0.000 title 1
- 239000012491 analyte Substances 0.000 abstract 2
- 238000000149 argon plasma sintering Methods 0.000 abstract 1
- 230000010287 polarization Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/587—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Nanotechnology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70466005P | 2005-08-02 | 2005-08-02 | |
| PCT/US2006/030268 WO2008048221A2 (en) | 2005-08-02 | 2006-08-02 | Nanostructures for polarized imaging and receptor/ligand quantization: breaking the diffraction limit for imaging |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE525655T1 true ATE525655T1 (de) | 2011-10-15 |
Family
ID=39314502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06851637T ATE525655T1 (de) | 2005-08-02 | 2006-08-02 | Nanostrukturen zur polarisierten abbildung und rezeptor-/liganden-quantifizierung: überschreitung der diffraktionsgrenze für abbildungen |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8987004B2 (de) |
| EP (1) | EP1957987B1 (de) |
| AT (1) | ATE525655T1 (de) |
| CA (1) | CA2659640C (de) |
| WO (1) | WO2008048221A2 (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2655079C (en) * | 2005-06-15 | 2013-12-10 | University Of Maryland Biotechnology Institute | Bioassays using plasmonic scattering from noble metal nanostructures |
| US9500590B2 (en) | 2006-02-13 | 2016-11-22 | University Of Maryland, Baltimore County | Assays for pathogen detection using microwaves for lysing and accelerating metal-enhanced fluorescence |
| US9339485B2 (en) | 2007-03-02 | 2016-05-17 | University Of Maryland, Baltimore County | Plasmonic engineering of singlet oxygen and/or superoxide generation |
| US9023372B2 (en) | 2007-07-18 | 2015-05-05 | University Of Maryland | Metal-enhanced fluorescence nanoparticles |
| US8445217B2 (en) | 2007-09-20 | 2013-05-21 | Vanderbilt University | Free solution measurement of molecular interactions by backscattering interferometry |
| US8120777B2 (en) | 2007-12-10 | 2012-02-21 | Molecular Sensing, Inc. | Temperature-stable interferometer |
| WO2009148634A2 (en) * | 2008-01-30 | 2009-12-10 | University Of Maryland Biotechnology Institute | Conversion of just-continuous metallic films to large particulate substrates for metal-enhanced fluorescence |
| EP2257790B1 (de) | 2008-03-03 | 2016-12-07 | University Of Maryland Baltimore County | Verfahren und systeme für spannungsgesteuerte metallverstärkte fluoreszenz, chemilumineszenz oder biolumineszenz |
| CA2737048A1 (en) | 2008-09-11 | 2011-03-18 | University Of Maryland, Baltimore County | Sonication-assisted metal-enhanced fluorescence (samef)-based bioassays |
| WO2010033677A2 (en) | 2008-09-17 | 2010-03-25 | University Of Maryland Biotechnology Institute | Plasmonic electricity |
| US20100188665A1 (en) * | 2009-01-12 | 2010-07-29 | Molecular Sensing, Inc. | Methods and systems for interferometric analysis |
| EP2386060A2 (de) * | 2009-01-12 | 2011-11-16 | Molecular Sensing, Inc. | Probenentnahme und messung in einem einzelnen behälter mittels backscattering-interferometrie |
| US10024850B2 (en) | 2009-02-17 | 2018-07-17 | University Of Maryland, Baltimore County | Metal-enhanced bioluminescence: an approach for monitoring biological bioluminescent processes |
| WO2010096204A2 (en) | 2009-02-23 | 2010-08-26 | University Of Maryland Biotechnology Institute | Directional surface plasmon coupled fluorescence and chemiluminescence from thin films of nickel, iron or palladium and uses thereof |
| US8450118B2 (en) * | 2009-05-04 | 2013-05-28 | Molecular Sensing, Inc. | Method for detecting binding interactions between membrane proteins and analytes in a homogenous assay |
| US8722428B2 (en) | 2009-11-25 | 2014-05-13 | University Of Maryland, Baltimore County | Metal enhanced fluorescence from metallic nanoburger structures |
| WO2011081896A2 (en) | 2009-12-14 | 2011-07-07 | University Of Maryland, Baltimore County | Plasmonic electricity |
| EP2513630B1 (de) | 2009-12-17 | 2016-05-25 | Chris Geddes | Detektionssystem umfassend mischmetallsubstrate zur metallverstärkten fluoreszenz |
| EP2569394B1 (de) | 2010-05-11 | 2015-11-04 | University of Maryland, Baltimore County | Methode zur verbesserung der emissionen langlebiger lumineszierende verbindungen |
| US8962345B2 (en) * | 2010-05-21 | 2015-02-24 | The United States Of America As Represented By The Secretary Of Commerce | Method of characterizing glycans attached to glycoproteins |
| US9638632B2 (en) | 2010-06-11 | 2017-05-02 | Vanderbilt University | Multiplexed interferometric detection system and method |
| WO2012060882A2 (en) * | 2010-11-02 | 2012-05-10 | Molecular Sensing, Inc. | Interferometric detection using nanoparticles |
| US9562853B2 (en) | 2011-02-22 | 2017-02-07 | Vanderbilt University | Nonaqueous backscattering interferometric methods |
| US9829436B2 (en) | 2011-03-18 | 2017-11-28 | Chris Geddes | Metal-enhanced photoluminescence from carbon nanodots |
| US8735175B2 (en) | 2011-03-18 | 2014-05-27 | Chris D. Geddes | Multicolor microwave-accelerated metal-enhanced fluorescence (M-MAMEF) |
| GB2497317A (en) | 2011-12-06 | 2013-06-12 | Univ Dublin | System and method for the detection of analytes using rod-shaped nanoparticles |
| US9244012B2 (en) | 2011-09-26 | 2016-01-26 | University Of Maryland, Baltimore County | Enhanced luminescence from nanopolished surfaces and plate wells |
| US9273949B2 (en) | 2012-05-11 | 2016-03-01 | Vanderbilt University | Backscattering interferometric methods |
| US9816990B2 (en) | 2013-02-28 | 2017-11-14 | University Of Maryland, Baltimore County | Ultra-fast pathogen toxin detection assay based on microwave-accelerated metal-enhanced fluorescence |
| US10379050B2 (en) | 2015-01-13 | 2019-08-13 | University Of Maryland, Baltimore County | Spectral shifts and modifications in metal-enhanced fluorescence, phosphorescence and alpha-fluorescence |
| EP3247988A4 (de) | 2015-01-23 | 2018-12-19 | Vanderbilt University | Robustes interferometer und verfahren zur verwendung davon |
| US10294451B2 (en) | 2015-04-22 | 2019-05-21 | University Of Maryland, Baltimore County | Flow and static lysing systems and methods for ultra-rapid isolation and fragmentation of biological materials by microwave irradiation |
| WO2017015531A1 (en) | 2015-07-22 | 2017-01-26 | University Of Maryland, Baltimore County | Hydrophilic coatings of plasmonic metals to enable low volume metal-enhanced fluorescence |
| EP3408649B1 (de) | 2016-01-29 | 2023-06-14 | Vanderbilt University | Interferometrie mit antwortfunktion in freier lösung |
| EP4022280B1 (de) * | 2019-08-30 | 2025-06-25 | Centre national de la recherche scientifique | Verfahren und vorrichtung zur optischen charakterisierung von partikeln |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4174952A (en) * | 1978-01-23 | 1979-11-20 | Massachusetts Institute Of Technology | Immunoassay by light scattering intensity anisotropy measurements |
| NL7807532A (nl) * | 1978-07-13 | 1980-01-15 | Akzo Nv | Metaal-immunotest. |
| US4444879A (en) * | 1981-01-29 | 1984-04-24 | Science Research Center, Inc. | Immunoassay with article having support film and immunological counterpart of analyte |
| US5017009A (en) * | 1986-06-26 | 1991-05-21 | Ortho Diagnostic Systems, Inc. | Scattered total internal reflectance immunoassay system |
| GB8807488D0 (en) | 1988-03-29 | 1988-05-05 | Ares Serono Res & Dev Ltd | Method of assay |
| CA2076709A1 (en) * | 1992-08-24 | 1994-02-25 | Ulrich J. Krull | Amplified fluorescence emission for chemical transduction |
| AT403961B (de) * | 1995-03-17 | 1998-07-27 | Avl Verbrennungskraft Messtech | Optochemisches messsystem mit einem fluoreszenzsensor |
| JP2000510582A (ja) * | 1996-04-25 | 2000-08-15 | ゼニコン・サイエンシーズ・コーポレーション | 微粒子標識を使用した分析物アッセイ |
| EP0979409B1 (de) * | 1997-02-20 | 2006-12-27 | The Regents of the University of California | Plasmon-schwingteilchen, methode und vorrichtung |
| US20010053521A1 (en) * | 1999-09-27 | 2001-12-20 | Kreimer David I. | Amplification of analyte detection by substrates having particle structures with receptors |
| US7348182B2 (en) * | 2000-10-03 | 2008-03-25 | Mirari Biosciences, Inc. | Directed microwave chemistry |
| WO2002029076A1 (en) * | 2000-10-03 | 2002-04-11 | Mirari Biosciences, Inc. | Methods and compositions for directed microwave chemistry |
| US20040009540A1 (en) * | 2001-04-27 | 2004-01-15 | Genoptix, Inc | Detection and evaluation of cancer cells using optophoretic analysis |
| EP1499875A4 (de) * | 2002-04-30 | 2007-10-03 | Univ Maryland | Fluoreszenzwahrnehmung |
| US7095502B2 (en) * | 2002-08-06 | 2006-08-22 | Joseph Lakowicz | Optical structures for metal-enhanced sensing |
| AU2003268537A1 (en) | 2002-09-10 | 2004-04-30 | University Of Maryland, Baltimore | Use of metallic particles to improve fluorescence imaging |
| US7122384B2 (en) * | 2002-11-06 | 2006-10-17 | E. I. Du Pont De Nemours And Company | Resonant light scattering microparticle methods |
| AU2003296014B2 (en) * | 2002-11-26 | 2010-06-03 | University Of Maryland Biotechnology Institute | High-sensitivity assays for pathogen detection using metal-enhanced fluorescence |
| ATE532061T1 (de) * | 2003-09-17 | 2011-11-15 | Univ Maryland | Cyanid wahrnehmende verbindungen und verwendungen davon |
| US7846412B2 (en) * | 2003-12-22 | 2010-12-07 | Emory University | Bioconjugated nanostructures, methods of fabrication thereof, and methods of use thereof |
| US7253452B2 (en) * | 2004-03-08 | 2007-08-07 | Massachusetts Institute Of Technology | Blue light emitting semiconductor nanocrystal materials |
| WO2006050257A2 (en) * | 2004-10-29 | 2006-05-11 | Massachusetts Institute Of Tecchnology | Detection of ion channel or receptor activity |
| US8034633B2 (en) | 2004-11-19 | 2011-10-11 | University Of Maryland, Baltimore County | Microwave accelerated assays |
| EP1856520B1 (de) | 2005-01-03 | 2015-06-17 | University Of Maryland Baltimore County | Mikrowellenbeschleunigte plasmonics |
| CA2655079C (en) | 2005-06-15 | 2013-12-10 | University Of Maryland Biotechnology Institute | Bioassays using plasmonic scattering from noble metal nanostructures |
| EP1896832A4 (de) | 2005-06-17 | 2011-12-14 | Univ Maryland Biotech Inst | Metallverstärkte messverfahren auf fluoreszenzbasis |
| EP2024488B1 (de) | 2006-02-13 | 2018-01-17 | Chris Geddes | Metallverbesserte chemilumineszenz (mec) |
| US8980179B2 (en) * | 2006-05-17 | 2015-03-17 | University Of Maryland, Baltimore County | Angular-dependent metal-enhanced fluorescence |
| US9023372B2 (en) * | 2007-07-18 | 2015-05-05 | University Of Maryland | Metal-enhanced fluorescence nanoparticles |
-
2006
- 2006-08-02 US US11/997,778 patent/US8987004B2/en not_active Expired - Fee Related
- 2006-08-02 CA CA2659640A patent/CA2659640C/en not_active Expired - Fee Related
- 2006-08-02 AT AT06851637T patent/ATE525655T1/de not_active IP Right Cessation
- 2006-08-02 WO PCT/US2006/030268 patent/WO2008048221A2/en not_active Ceased
- 2006-08-02 EP EP06851637A patent/EP1957987B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| EP1957987A4 (de) | 2009-08-26 |
| US8987004B2 (en) | 2015-03-24 |
| EP1957987B1 (de) | 2011-09-21 |
| CA2659640A1 (en) | 2008-04-24 |
| CA2659640C (en) | 2011-11-15 |
| WO2008048221A3 (en) | 2008-12-11 |
| US20090325199A1 (en) | 2009-12-31 |
| WO2008048221A2 (en) | 2008-04-24 |
| EP1957987A2 (de) | 2008-08-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |