ATE526583T1 - Immunomagnetische erfassung und abbildung biologischer zielmoleküle - Google Patents

Immunomagnetische erfassung und abbildung biologischer zielmoleküle

Info

Publication number
ATE526583T1
ATE526583T1 AT09700945T AT09700945T ATE526583T1 AT E526583 T1 ATE526583 T1 AT E526583T1 AT 09700945 T AT09700945 T AT 09700945T AT 09700945 T AT09700945 T AT 09700945T AT E526583 T1 ATE526583 T1 AT E526583T1
Authority
AT
Austria
Prior art keywords
imaging
biological target
biological
target molecules
sample
Prior art date
Application number
AT09700945T
Other languages
English (en)
Inventor
Bruce Bernard
Kurt Hoffacker
Chuck Collins
Original Assignee
Luminex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luminex Corp filed Critical Luminex Corp
Application granted granted Critical
Publication of ATE526583T1 publication Critical patent/ATE526583T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT09700945T 2008-01-07 2009-01-07 Immunomagnetische erfassung und abbildung biologischer zielmoleküle ATE526583T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1948208P 2008-01-07 2008-01-07
PCT/US2009/030281 WO2009089254A1 (en) 2008-01-07 2009-01-07 Immunomagnetic capture and imaging of biological targets

Publications (1)

Publication Number Publication Date
ATE526583T1 true ATE526583T1 (de) 2011-10-15

Family

ID=40352254

Family Applications (1)

Application Number Title Priority Date Filing Date
AT09700945T ATE526583T1 (de) 2008-01-07 2009-01-07 Immunomagnetische erfassung und abbildung biologischer zielmoleküle

Country Status (7)

Country Link
US (1) US8318445B2 (de)
EP (1) EP2240775B1 (de)
JP (1) JP2011509405A (de)
CN (1) CN101939648B (de)
AT (1) ATE526583T1 (de)
CA (1) CA2711564A1 (de)
WO (1) WO2009089254A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8296088B2 (en) * 2006-06-02 2012-10-23 Luminex Corporation Systems and methods for performing measurements of one or more materials
JPWO2014007367A1 (ja) * 2012-07-05 2016-06-02 国立大学法人 東京大学 同一試料中の２種の物質を検出又は測定する方法
EP2871464B1 (de) * 2012-07-06 2021-07-28 Hitachi High-Tech Corporation Analysevorrichtung und analyseverfahren
EP2980588B1 (de) * 2014-07-31 2017-10-18 Betelgeux, S. L. Verfahren und Vorrichtung zum Nachweis von Mikroorganismen
CN105717033B (zh) * 2016-01-25 2019-05-14 王博 一种流式细胞仪定量检测蛋白质浓度的方法
US10527608B2 (en) 2017-06-13 2020-01-07 Genetics Research, Llc Methods for rare event detection
US10081829B1 (en) 2017-06-13 2018-09-25 Genetics Research, Llc Detection of targeted sequence regions
US10947599B2 (en) 2017-06-13 2021-03-16 Genetics Research, Llc Tumor mutation burden
US11142788B2 (en) 2017-06-13 2021-10-12 Genetics Research, Llc Isolation of target nucleic acids
CN109991410B (zh) * 2017-12-29 2022-07-05 上海白泽医学检验所有限公司 一种含抗cd45单抗的组合物及其使用方法
WO2019176275A1 (ja) * 2018-03-12 2019-09-19 ソニー株式会社 細胞評価装置及び細胞評価システム

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4230685A (en) * 1979-02-28 1980-10-28 Northwestern University Method of magnetic separation of cells and the like, and microspheres for use therein
NO180658C (no) * 1994-03-10 1997-05-21 Oeystein Fodstad Fremgangsmåte og anordning for deteksjon av spesifikke målceller i spesialiserte eller blandede cellepopulasjoner og opplösninger som inneholder blandede cellepopulasjoner
US5736330A (en) * 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences
WO1997014028A2 (en) * 1995-10-11 1997-04-17 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
US5981180A (en) * 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
JP3996644B2 (ja) * 1996-06-07 2007-10-24 イムニベスト・コーポレイション 外部及び内部勾配を有する磁気分離
US6449562B1 (en) * 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
CA2306501C (en) * 1997-10-14 2011-03-29 Luminex Corporation Precision fluorescently dyed particles and methods of making and using same
ATE239801T1 (de) * 1998-01-22 2003-05-15 Luminex Corp Mikropartikel mit multiplen fluoreszenz-signalen
WO1999045094A1 (en) * 1998-03-02 1999-09-10 Compucyte Corp. Selective cell analysis
WO2001013119A1 (en) * 1999-08-17 2001-02-22 Luminex Corporation Encapsulation of fluorescent particles
WO2001078087A2 (en) * 2000-04-06 2001-10-18 Luminex Corporation Magnetically-responsive microspheres
CA2474509C (en) * 2002-02-14 2012-01-31 Immunivest Corporation Methods and algorithms for cell enumeration in a low-cost cytometer
US7282180B2 (en) * 2003-07-02 2007-10-16 Immunivest Corporation Devices and methods to image objects
WO2005085810A1 (en) * 2003-08-21 2005-09-15 University Of Massachusetts Medical Center Rapid plague detection system
US20060216696A1 (en) * 2004-08-23 2006-09-28 Goguen Jon D Rapid plague detection system
WO2006041453A1 (en) 2004-09-30 2006-04-20 Immunivest Corporation Circulating tumor cells (ctc’s): apoptotic assessment in prostate cancer patients
WO2006079016A1 (en) * 2005-01-20 2006-07-27 Luminex Corporation Magnetic microspheres for use in fluorescence-based applications
EP4071458B1 (de) * 2005-09-21 2025-11-05 Luminex Corporation Verfahren und systeme für die bilddatenverarbeitung
EP2024893B1 (de) * 2006-05-12 2015-03-04 Janssen Diagnostics, LLC Laserbeleuchtungssystem in einem fluoreszenzmikroskop
CN101479603B (zh) * 2006-06-02 2012-11-21 卢米尼克斯股份有限公司 包括使用磁粒子和应用磁场的用于执行一种或多种分析物的测量系统和方法

Also Published As

Publication number Publication date
CN101939648B (zh) 2013-09-04
CA2711564A1 (en) 2009-07-16
WO2009089254A1 (en) 2009-07-16
US8318445B2 (en) 2012-11-27
HK1151094A1 (en) 2012-01-20
US20090176255A1 (en) 2009-07-09
EP2240775A1 (de) 2010-10-20
EP2240775B1 (de) 2011-09-28
CN101939648A (zh) 2011-01-05
JP2011509405A (ja) 2011-03-24

Similar Documents

Publication Publication Date Title
ATE526583T1 (de) Immunomagnetische erfassung und abbildung biologischer zielmoleküle
BRPI0720361A8 (pt) Método para medir aglutinação de uma ou mais partículas em um ensaio de aglutinação induzida por alvo efetuado em uma câmara de reação, e, kit e dispositivo para medir um ou mais parâmetros de aglutinação de partículas em um ensaio de aglutinação induzida por alvo
NZ703227A (en) A method and a system for quantitative or qualitative determination of a target component
BRPI0809138B8 (pt) método para detectar a presença ou quantidade de um ou mais analitos em uma amostra biológica
DK2132339T3 (da) Fremgangsmåde til detektering af en analyt i en biologisk matrix
NZ629703A (en) Methods and compositions for detecting multiple analytes with a single signal
MX2009013388A (es) Analisis multiple de muestras de sangre.
EP4024029A3 (de) Systeme und verfahren zur maximierung der verwendung einer probe
IL188599A0 (en) Methods and substances for isolating microrna
WO2009140326A3 (en) Microfluidic isolation of tumor cells or other rare cells from whole blood or other liquids
CA2482173A1 (en) Method for detecting low concentrations of a target bacterium that uses phages to infect target bacterial cells
EA200971123A1 (ru) Мультиплексный способ выявления инфекции
NO20076662L (no) Deteksjon av et malantigen uavhengig av tilstedevaerelse eller fravaer av et korresponderende terapeutisk antistoff
BR112014027465A8 (pt) método de teste in vitro, kit de detecção, usos do kit, método in vitro de diagnóstico e método para fabricar um kit
WO2013074520A3 (en) Detection, isolation and analysis of rare cells in biological fluids
NZ609824A (en) Immunochromatography devices, methods and kits
WO2012103337A3 (en) Assays and methods to sequence microbes directly from immune complexes
MX353566B (es) Metodos y sistemas para amplificacion de señal de bioensayos.
WO2008152528A3 (en) Method for the diagnosis or the screening of an arbovirus infection, reagents useful in said method and their applications
PL1989544T3 (pl) Testy na komórkach T
WO2011137388A3 (en) Identification and use of biomarkers for detection and quantification of the level of radiation exposure in a biological sample
EA201370030A1 (ru) Бифункциональный количественный анализ in vitro связывания мишени для обнаружения нейтрализующих антител к антителам-мишеням
US20190079094A1 (en) Subcellular localization of target analytes
ATE545012T1 (de) VORRICHTUNGEN UND VERFAHREN ZUR ABBILDUNG VON OBJEKTEN MITTELS ßTIME DELAY INTEGRATIONß
GB0506183D0 (en) Antigen detection

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties