ATE526585T1 - Natürlicher ligand des g-protein-gekoppelten rezeptors rcc356 und verwendungen davon - Google Patents
Natürlicher ligand des g-protein-gekoppelten rezeptors rcc356 und verwendungen davonInfo
- Publication number
- ATE526585T1 ATE526585T1 AT06707378T AT06707378T ATE526585T1 AT E526585 T1 ATE526585 T1 AT E526585T1 AT 06707378 T AT06707378 T AT 06707378T AT 06707378 T AT06707378 T AT 06707378T AT E526585 T1 ATE526585 T1 AT E526585T1
- Authority
- AT
- Austria
- Prior art keywords
- rcc356
- coupled receptor
- natural ligand
- protein
- isovaleric acid
- Prior art date
Links
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 title abstract 3
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 title abstract 3
- 239000003446 ligand Substances 0.000 title abstract 2
- XYHKNCXZYYTLRG-UHFFFAOYSA-N 1h-imidazole-2-carbaldehyde Chemical compound O=CC1=NC=CN1 XYHKNCXZYYTLRG-UHFFFAOYSA-N 0.000 abstract 3
- GWYFCOCPABKNJV-UHFFFAOYSA-M 3-Methylbutanoic acid Natural products CC(C)CC([O-])=O GWYFCOCPABKNJV-UHFFFAOYSA-M 0.000 abstract 3
- GWYFCOCPABKNJV-UHFFFAOYSA-N beta-methyl-butyric acid Natural products CC(C)CC(O)=O GWYFCOCPABKNJV-UHFFFAOYSA-N 0.000 abstract 3
- 230000003993 interaction Effects 0.000 abstract 2
- 238000007423 screening assay Methods 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Neurosurgery (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05447046 | 2005-03-03 | ||
| PCT/EP2006/001904 WO2006094704A2 (en) | 2005-03-03 | 2006-03-02 | Natural ligand of g protein coupled receptor rcc356 and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE526585T1 true ATE526585T1 (de) | 2011-10-15 |
Family
ID=35344663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06707378T ATE526585T1 (de) | 2005-03-03 | 2006-03-02 | Natürlicher ligand des g-protein-gekoppelten rezeptors rcc356 und verwendungen davon |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8008023B2 (de) |
| EP (1) | EP1864131B1 (de) |
| JP (1) | JP5307404B2 (de) |
| AT (1) | ATE526585T1 (de) |
| AU (1) | AU2006222265B2 (de) |
| CA (1) | CA2597255C (de) |
| DK (1) | DK1864131T3 (de) |
| ES (1) | ES2373913T3 (de) |
| WO (1) | WO2006094704A2 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8263417B2 (en) * | 2006-01-04 | 2012-09-11 | The Board Of Trustees Of The Leland Stanford Junior University | Self-illuminating dot systems and methods of use thereof |
| JP4980418B2 (ja) * | 2007-03-19 | 2012-07-18 | 株式会社リバース・プロテオミクス研究所 | 創薬標的タンパク質及び標的遺伝子、並びにスクリーニング方法 |
| GB201020133D0 (en) * | 2010-11-26 | 2011-01-12 | Royal Holloway & Bedford New College | Therapeutic use of compounds |
| US8637259B1 (en) * | 2011-02-09 | 2014-01-28 | Chemcom S.A. | Methods of identifying modulators of olfactory receptors involved in the perception of sweat carboxylic acids |
| RU2612017C2 (ru) * | 2011-04-07 | 2017-03-01 | Де Скриппс Рисерч Инститьют | Высокопроизводительный скрининг соединений, модулирующих экспрессию клеточных макромолекул |
| EP2753643A2 (de) * | 2011-09-08 | 2014-07-16 | Institut National De La Recherche Agronomique (INRA) | Neuer pheromonrezeptor aus spodoptera littoralis (lepidoptera, noctuidae) und identifizierung eines natürlichen liganden des besagten rezeptors sowie seine verwendung |
| JP5948139B2 (ja) * | 2012-05-11 | 2016-07-06 | ヒノキ新薬株式会社 | サーチュイン1(sirt1)遺伝子活性化剤 |
| DK3004157T3 (en) | 2013-05-31 | 2017-12-11 | Chemcom Sa | OLFACTORY RECEPTORS INVOLVED IN THE PERCEPTION OF SWEET CARBOXYLIC ACIDS AND THE USE THEREOF |
| US10429300B2 (en) | 2015-01-26 | 2019-10-01 | The Johns Hopkins University | Surface plasmon resonance approach to monitor protein-ligand interactions |
| JP6371336B2 (ja) | 2015-06-17 | 2018-08-08 | 花王株式会社 | ポリスルフィド化合物の臭いの抑制剤 |
| JP6122181B2 (ja) | 2015-06-17 | 2017-04-26 | 花王株式会社 | スルフィド化合物の臭いの抑制剤の評価又は選択方法 |
| US20200240978A1 (en) * | 2017-08-17 | 2020-07-30 | Komi Hakko Corporation | Method for quantifying odors, cells used in same, and method for producing said cells |
| JP7263355B2 (ja) | 2017-12-05 | 2023-04-24 | ケムコム エス アー | ムスクの香りの知覚に関与する嗅覚受容体およびその使用 |
| CN112143547B (zh) * | 2020-09-22 | 2022-07-15 | 上海桉欣新能源科技有限公司 | 一种制冷压缩机用润滑油及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4272376B2 (ja) * | 1999-10-05 | 2009-06-03 | アジェンシス,インコーポレイテッド | 前立腺ガンにおいてアップレギュレートされるgタンパク質結合レセプターおよびその使用 |
| US7361338B2 (en) * | 1999-10-05 | 2008-04-22 | Agensys, Inc. | Methods to inhibit growth of prostate cancer cells |
| AU2002220265A1 (en) * | 2000-11-03 | 2002-05-15 | University Of Vermont And State Agricultural College | Compositions for inhibiting grb7 |
| US7189507B2 (en) * | 2001-06-18 | 2007-03-13 | Pdl Biopharma, Inc. | Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer |
| US20030096299A1 (en) * | 2001-07-09 | 2003-05-22 | Valerie Wittamer | Natural ligand of G protein coupled receptor ChemR23 and uses thereof |
| WO2003057730A1 (en) * | 2002-01-07 | 2003-07-17 | Euroscreen S.A. | Ligand for g-protein coupled receptor gpr43 and uses thereof |
-
2006
- 2006-03-02 DK DK06707378.3T patent/DK1864131T3/da active
- 2006-03-02 WO PCT/EP2006/001904 patent/WO2006094704A2/en not_active Ceased
- 2006-03-02 EP EP06707378A patent/EP1864131B1/de not_active Expired - Lifetime
- 2006-03-02 JP JP2007557423A patent/JP5307404B2/ja not_active Expired - Fee Related
- 2006-03-02 CA CA2597255A patent/CA2597255C/en not_active Expired - Fee Related
- 2006-03-02 AU AU2006222265A patent/AU2006222265B2/en not_active Ceased
- 2006-03-02 ES ES06707378T patent/ES2373913T3/es not_active Expired - Lifetime
- 2006-03-02 AT AT06707378T patent/ATE526585T1/de active
-
2008
- 2008-05-12 US US12/152,275 patent/US8008023B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008538278A (ja) | 2008-10-23 |
| CA2597255A1 (en) | 2006-09-14 |
| JP5307404B2 (ja) | 2013-10-02 |
| AU2006222265B2 (en) | 2012-07-05 |
| WO2006094704A3 (en) | 2006-11-09 |
| EP1864131A2 (de) | 2007-12-12 |
| EP1864131B1 (de) | 2011-09-28 |
| US8008023B2 (en) | 2011-08-30 |
| AU2006222265A1 (en) | 2006-09-14 |
| CA2597255C (en) | 2014-05-27 |
| US20090264526A1 (en) | 2009-10-22 |
| DK1864131T3 (da) | 2011-10-31 |
| ES2373913T3 (es) | 2012-02-10 |
| WO2006094704A2 (en) | 2006-09-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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