ATE526972T1 - Kaliumkanalhemmer - Google Patents

Kaliumkanalhemmer

Info

Publication number: ATE526972T1
Authority: AT; Austria
Prior art keywords: potassium channel; channel inhibitors; derivatives; inhibitors; useful
Prior art date: 2006-02-01

Application number

AT07717099T

Other languages

English (en)

Inventor

B Wesley Trotter

Kausik Nanda

Nathan Kett

Original Assignee

Merck Sharp & Dohme

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-02-01

Filing date

2007-01-29

Publication date

2011-10-15

2007-01-29 Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme

2011-10-15 Application granted granted Critical

2011-10-15 Publication of ATE526972T1 publication Critical patent/ATE526972T1/de

Links

102000004257 Potassium Channel Human genes 0.000 title abstract 2
239000003112 inhibitor Substances 0.000 title abstract 2
108020001213 potassium channel Proteins 0.000 title abstract 2
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical class CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
206010003119 arrhythmia Diseases 0.000 abstract 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Immunology (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Vascular Medicine (AREA)
Hematology (AREA)
Neurosurgery (AREA)
Ophthalmology & Optometry (AREA)
Gastroenterology & Hepatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT07717099T 2006-02-01 2007-01-29 Kaliumkanalhemmer ATE526972T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US76405906P	2006-02-01	2006-02-01
PCT/US2007/002337 WO2007089678A2 (en)	2006-02-01	2007-01-29	Potassium channel inhibitors

Publications (1)

Publication Number	Publication Date
ATE526972T1 true ATE526972T1 (de)	2011-10-15

Family

ID=38327948

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT07717099T ATE526972T1 (de)	2006-02-01	2007-01-29	Kaliumkanalhemmer

Country Status (7)

Country	Link
US (1)	US8080543B2 (de)
EP (1)	EP1994029B1 (de)
JP (1)	JP5268651B2 (de)
AT (1)	ATE526972T1 (de)
AU (1)	AU2007210013B2 (de)
CA (1)	CA2641110A1 (de)
WO (1)	WO2007089678A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN119775100B (zh) *	2024-12-30	2025-11-28	南京林业大学	一种光诱导铬催化β-氘代醇的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY125533A (en)	1999-12-06	2006-08-30	Bristol Myers Squibb Co	Heterocyclic dihydropyrimidine compounds
CN1993348A (zh) *	2004-07-29	2007-07-04	默克公司	钾通道抑制剂
US7879839B2 (en)	2004-07-29	2011-02-01	Merck Sharp & Dohme Corp.	Potassium channel inhibitors

2007
- 2007-01-29 EP EP07717099A patent/EP1994029B1/de not_active Not-in-force
- 2007-01-29 AT AT07717099T patent/ATE526972T1/de not_active IP Right Cessation
- 2007-01-29 AU AU2007210013A patent/AU2007210013B2/en not_active Ceased
- 2007-01-29 CA CA002641110A patent/CA2641110A1/en not_active Abandoned
- 2007-01-29 WO PCT/US2007/002337 patent/WO2007089678A2/en not_active Ceased
- 2007-01-29 JP JP2008553278A patent/JP5268651B2/ja not_active Expired - Fee Related
- 2007-01-29 US US12/223,354 patent/US8080543B2/en active Active

Also Published As

Publication number	Publication date
AU2007210013B2 (en)	2011-08-18
EP1994029A2 (de)	2008-11-26
JP5268651B2 (ja)	2013-08-21
JP2009525331A (ja)	2009-07-09
WO2007089678A2 (en)	2007-08-09
US20090069283A1 (en)	2009-03-12
WO2007089678A3 (en)	2007-11-15
CA2641110A1 (en)	2007-08-09
EP1994029B1 (de)	2011-10-05
AU2007210013A1 (en)	2007-08-09
US8080543B2 (en)	2011-12-20
EP1994029A4 (de)	2010-05-26

Legal Events

Date	Code	Title	Description
2012-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
NO20082298L (no)	2008-07-17	Kaliumkanalinhibitorer
WO2007136592A3 (en)	2008-02-28	2-0x0-l,2-dihydr0quin0line derivatives, compositions, and uses thereof as antiproliferative agents
LTC1907382I2 (lt)	2017-11-10	Nitrokatechnolio dariniai, kaip COMT inhibitoriai
CL2011000957A1 (es)	2011-09-16	Compuesto derivados de isoindolina sustituidos, inhibidores de citosinas tnf-a; composicion farmaceutica; utiles en el tratamiento del cancer.
EA201001359A1 (ru)	2011-04-29	Гетероциклические соединения в качестве ингибиторов cxcr2
WO2006015159A3 (en)	2006-07-20	Potassium channel inhibitors
AU2009236256A8 (en)	2013-12-05	Small molecule inhibitors of the pleckstrin homology domain and methods for using same
CY1115633T1 (el)	2017-01-04	Παραγωγα πυραζολο πυριδινης ως αναστολεις της nadph οξειδασης
BRPI0818672A2 (pt)	2015-04-14	2'-fluor-2'-desoxitetra-hidrouridinas como inibidores da citidina desaminase
NO20091395L (no)	2009-04-06	Nye tiofenderivater
NO20060202L (no)	2006-01-13	Pyrrolodihydroisokinoliner som PDE-10-inhibitorer
EA200601391A1 (ru)	2006-12-29	Производные хинолина для применения в качестве микобактериальных ингибиторов
ATE554066T1 (de)	2012-05-15	Entzündungshemmende substituierte cyclobutendionverbindungen
DE602008005141D1 (de)	2011-04-07	1,3-dihydroimidazol-2-thionderivate als inhibitoren von dopamin-beta-hydroxylase
UA106880C2 (uk)	2014-10-27	Нові гербіциди
NO20081207L (no)	2008-05-27	Isoquinolines as IGF-1R inhibitors
ATE549024T1 (de)	2012-03-15	Chinazolin-kaliumkanalhemmer
NO20071805L (no)	2007-06-07	Alkylidentetrahydronaftalenderivater, fremgangsmate for deres fremstilling og deres anvendelse som betennelseshemmere.
DE602004028493D1 (de)	2010-09-16	Isochinolinon-kaliumkanalinhibitoren
WO2007050348A3 (en)	2007-10-04	Potassium channel inhibitors
ATE445593T1 (de)	2009-10-15	Acetylenderivate
EA200801366A1 (ru)	2008-10-30	Производные 3,6-дигидро-2-оксо-6н-1,3,4-тиадиазина
WO2007089735A3 (en)	2007-11-29	Potassium channel inhibitors
WO2007089743A3 (en)	2007-12-13	Potassium channel inhibitors
NO20091386L (no)	2009-05-06	Fenyloksyanilinderivater