ATE527285T1 - Anti-muc1-alpha-beta-antikörper - Google Patents

Anti-muc1-alpha-beta-antikörper

Info

Publication number
ATE527285T1
ATE527285T1 AT06734050T AT06734050T ATE527285T1 AT E527285 T1 ATE527285 T1 AT E527285T1 AT 06734050 T AT06734050 T AT 06734050T AT 06734050 T AT06734050 T AT 06734050T AT E527285 T1 ATE527285 T1 AT E527285T1
Authority
AT
Austria
Prior art keywords
muc1
alpha beta
beta antibodies
antibodies
alpha
Prior art date
Application number
AT06734050T
Other languages
English (en)
Inventor
Daniel Rubinstein
Daniel Wreschner
Original Assignee
Univ Ramot
Biomodifying Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ramot, Biomodifying Llc filed Critical Univ Ramot
Application granted granted Critical
Publication of ATE527285T1 publication Critical patent/ATE527285T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • C07K16/3092—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT06734050T 2005-01-28 2006-01-27 Anti-muc1-alpha-beta-antikörper ATE527285T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64787005P 2005-01-28 2005-01-28
PCT/US2006/003213 WO2006081553A2 (en) 2005-01-28 2006-01-27 ANTI-MUC1 α/ß ANTIBODIES

Publications (1)

Publication Number Publication Date
ATE527285T1 true ATE527285T1 (de) 2011-10-15

Family

ID=36741145

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06734050T ATE527285T1 (de) 2005-01-28 2006-01-27 Anti-muc1-alpha-beta-antikörper

Country Status (8)

Country Link
US (2) US20080226619A1 (de)
EP (1) EP1848804B1 (de)
JP (1) JP2008528623A (de)
CN (1) CN101175855A (de)
AT (1) ATE527285T1 (de)
AU (1) AU2006209246A1 (de)
CA (1) CA2595778A1 (de)
WO (1) WO2006081553A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008035350A1 (en) * 2006-09-21 2008-03-27 Vaxil Biotherapeutics Ltd. Antigen specific multi epitope vaccines
CN102356316B (zh) * 2009-03-05 2015-07-08 独立行政法人产业技术综合研究所 肝内胆管癌的检出、辨别方法
WO2012173228A1 (ja) * 2011-06-16 2012-12-20 国立大学法人東京工業大学 ３´硫酸化コア１糖鎖に結合するプローブを用いるムチン１の分析方法、及び乳癌の検出又はモニタリング方法
WO2013023162A2 (en) * 2011-08-10 2013-02-14 Genus Oncology, Llc Anti-muc1 antibodies for cancer diagnostics
US10369104B2 (en) * 2014-04-01 2019-08-06 Children's Hospital Los Angeles Targeted polymerized nanoparticles for cancer treatment
RU2652901C1 (ru) * 2016-12-23 2018-05-03 Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Нижегородский государственный университет им. Н.И. Лобачевского" Антитела, связывающие опухолеассоциированный MUC1, и способы их получения
SG11202010496WA (en) 2018-05-18 2020-12-30 Daiichi Sankyo Co Ltd Anti-muc1 antibody-drug conjugate
AU2021239078A1 (en) * 2020-03-18 2022-08-11 Biomodifying, Llc Anti-MUC1-Sea Antibodies
WO2025027554A1 (en) 2023-07-31 2025-02-06 Sun Pharma Advanced Research Company Limited Humanized muc1 antibody and antibody drug conjugate

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
AUPM322393A0 (en) * 1993-12-24 1994-01-27 Austin Research Institute, The Mucin carbohydrate compounds and their use in immunotherapy
IL110464A0 (en) * 1994-07-26 1994-10-21 Univ Ramot Novel proteins for the diagnosis, imaging, and therapy of human cancer
GB9827228D0 (en) * 1998-12-10 1999-02-03 Univ Nottingham Cancer detection method and reagents
GB9904695D0 (en) 1999-03-01 1999-04-21 Imp Cancer Res Tech Peptide
US6716966B1 (en) * 1999-08-18 2004-04-06 Altarex Corp. Therapeutic binding agents against MUC-1 antigen and methods for their use
ATE290879T1 (de) * 1999-08-18 2005-04-15 Altarex Medical Corp Therapeutische antikörper gegen das muc-1 antigen und verfahren zu deren verwendung
JP2003533181A (ja) * 2000-02-01 2003-11-11 ジ・オースティン・リサーチ・インスティテュート ムチン−１誘導抗原および免疫療法におけるその使用
WO2001070265A2 (en) * 2000-03-24 2001-09-27 Biomira, Inc. Lipopeptide adjuvants
WO2001075110A2 (en) * 2000-03-30 2001-10-11 Dyax Corp. Mucin-1 specific binding members and methods of use thereof
JP5165175B2 (ja) * 2000-09-11 2013-03-21 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド Ｍｕｃ１細胞外ドメインおよびそれから得られた癌治療組成物
EP2241887B1 (de) * 2000-11-27 2015-01-14 Minerva Biotechnologies Corporation Diagnostika, Drogenscreening und Behandlung für Krebs
EP1531842A4 (de) * 2000-12-22 2007-03-07 Dana Farber Cancer Inst Inc Regulation des zellwachstums durch muc1
JP2005508839A (ja) * 2001-03-29 2005-04-07 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド ペプチドおよびｍｕｃ１タンパク質に対する抗体
JP2004536578A (ja) * 2001-03-30 2004-12-09 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 腫瘍ターゲティング用の抗−ｍｕｃ−１単鎖抗体
US7183388B2 (en) * 2001-03-30 2007-02-27 The Regents Of The University Of California Anti-MUC-1 single chain antibodies for tumor targeting
WO2003031569A2 (en) * 2001-10-10 2003-04-17 Centocor, Inc. Nucleic acid vaccines using tumor antigen encoding nucleic acids with cytokine adjuvant encoding nucleic acid
US6716627B2 (en) * 2001-12-20 2004-04-06 Isis Pharmaceuticals, Inc. Antisense modulation of mucin 1, transmembrane expression
ES2375992T3 (es) * 2002-04-15 2012-03-08 Oncothyreon Inc. Glucolipopéptidos sintéticos como vacunas.
WO2003089451A2 (en) * 2002-04-22 2003-10-30 Dyax Corporation Antibodies specific for mucin polypeptide
EP1517700B1 (de) 2002-04-22 2012-03-28 Recopharma AB Mucin-fusionspolypeptid-vakzine, zusammensetzungen und ihre verwendung
GB0212046D0 (en) * 2002-05-24 2002-07-03 Glaxo Group Ltd Vaccines
GB0212036D0 (en) * 2002-05-24 2002-07-03 Glaxo Group Ltd Vaccines
KR20050010040A (ko) * 2002-06-11 2005-01-26 글락소스미스클라인 바이오로지칼즈 에스.에이. 면역원성 조성물
RU2005100777A (ru) * 2002-06-14 2005-08-27 Иммуномедикс, Инк. (Us) Моноклональное антитело рам4 и его применение для диагностики и лечения рака поджелудочной железы
ES2524767T3 (es) * 2002-06-14 2014-12-12 Immunomedics, Inc. Anticuerpo monoclonal humanizado HPAM4
CA2491017A1 (en) 2002-07-03 2004-01-15 Immunogen, Inc. Antibodies to non-shed muc1 and muc16, and uses thereof
DK1764372T3 (da) 2005-09-20 2009-11-30 Peter Jon Nelson Vævsinhibitor af metalloproteinaser (TIMP) bundet til glycosylphosphatidylinositol (GPI)-ankre til behandling af cancer

Also Published As

Publication number Publication date
EP1848804A2 (de) 2007-10-31
CN101175855A (zh) 2008-05-07
US8648172B2 (en) 2014-02-11
EP1848804B1 (de) 2011-10-05
JP2008528623A (ja) 2008-07-31
US20120207772A1 (en) 2012-08-16
AU2006209246A1 (en) 2006-08-03
WO2006081553A3 (en) 2006-10-05
CA2595778A1 (en) 2006-08-03
US20080226619A1 (en) 2008-09-18
EP1848804A4 (de) 2009-05-13
WO2006081553A2 (en) 2006-08-03

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