ATE529124T1 - Verwendung des engrailed homeodomänen-proteins als anxiolytikum - Google Patents
Verwendung des engrailed homeodomänen-proteins als anxiolytikumInfo
- Publication number
- ATE529124T1 ATE529124T1 AT07731062T AT07731062T ATE529124T1 AT E529124 T1 ATE529124 T1 AT E529124T1 AT 07731062 T AT07731062 T AT 07731062T AT 07731062 T AT07731062 T AT 07731062T AT E529124 T1 ATE529124 T1 AT E529124T1
- Authority
- AT
- Austria
- Prior art keywords
- anxiolytic
- homeodomain protein
- engrailed
- engrailed homeodomain
- protein
- Prior art date
Links
- 239000002249 anxiolytic agent Substances 0.000 title abstract 2
- 102000009331 Homeodomain Proteins Human genes 0.000 title 1
- 108010048671 Homeodomain Proteins Proteins 0.000 title 1
- 230000000949 anxiolytic effect Effects 0.000 title 1
- 230000000648 anti-parkinson Effects 0.000 abstract 1
- 239000000939 antiparkinson agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229940125725 tranquilizer Drugs 0.000 abstract 1
- 239000003204 tranquilizing agent Substances 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Marine Sciences & Fisheries (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0601749A FR2897780B1 (fr) | 2006-02-28 | 2006-02-28 | Utilisation de la proteine a homeodomaine engrailed comme anxiolytique |
| PCT/FR2007/000360 WO2007099227A2 (fr) | 2006-02-28 | 2007-02-28 | Utilisation de la proteine a homeodomaine engrailed comme anxiolytique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE529124T1 true ATE529124T1 (de) | 2011-11-15 |
Family
ID=36950419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07731062T ATE529124T1 (de) | 2006-02-28 | 2007-02-28 | Verwendung des engrailed homeodomänen-proteins als anxiolytikum |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8575105B2 (de) |
| EP (1) | EP1993587B1 (de) |
| JP (1) | JP5205282B2 (de) |
| AT (1) | ATE529124T1 (de) |
| CA (1) | CA2643722C (de) |
| ES (1) | ES2376362T3 (de) |
| FR (1) | FR2897780B1 (de) |
| WO (1) | WO2007099227A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013128239A1 (en) | 2012-02-29 | 2013-09-06 | Centre National De La Recherche Scientifique | Use of engrailed for increasing dopamine synthesis by dopaminergic neurons |
| EP3352777B1 (de) | 2015-09-23 | 2021-09-15 | Centre National De La Recherche Scientifique | Engrailed zur verwendung in der behandlung von dna-schäden in einem patienten der an parkinson leidet |
| IL308224A (en) * | 2021-05-04 | 2024-01-01 | 2N Pharma Aps | Diazepane derivatives, processes for their preparation, and uses thereof for the amelioration, prevention and/or treatment of mental and neurological diseases |
| JP2026503094A (ja) | 2023-01-13 | 2026-01-27 | ブレインエバー | 安定化エングレイルドタンパク質水性組成物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2662698A1 (fr) * | 1990-06-05 | 1991-12-06 | Centre Nat Rech Scient | Nouveaux facteurs de croissance neurotropes comprenant un peptide homeoboite. |
| US5888762A (en) | 1990-06-05 | 1999-03-30 | Centre National De La Recherche Scientifique (Cnrs) | Neurotropic growth factors comprising a homeobox peptide |
| FR2739621B1 (fr) | 1995-10-05 | 1997-12-05 | Centre Nat Rech Scient | Peptides utilisables comme vecteurs pour l'adressage intracellulaire de molecules actives |
| FR2816845B1 (fr) | 2000-11-20 | 2006-10-20 | Centre Nat Rech Scient | Vecteurs de transport a travers un epithelium a jonctions serrees |
| FR2849603B1 (fr) | 2003-01-07 | 2006-09-08 | Centre Nat Rech Scient | Composition pour le transport intracellulaire de macromolecules ou particules biologiques |
| FR2855178B1 (fr) * | 2003-05-20 | 2005-08-05 | Centre Nat Rech Scient | Peptides modulateurs de l'activite du facteur de transcription engrailed |
| WO2005007812A2 (en) * | 2003-07-03 | 2005-01-27 | University Of Medicine And Dentistry Of New Jersey | Genes as diagnostic tools for autism |
-
2006
- 2006-02-28 FR FR0601749A patent/FR2897780B1/fr not_active Expired - Fee Related
-
2007
- 2007-02-28 CA CA2643722A patent/CA2643722C/fr active Active
- 2007-02-28 EP EP07731062A patent/EP1993587B1/de not_active Not-in-force
- 2007-02-28 ES ES07731062T patent/ES2376362T3/es active Active
- 2007-02-28 WO PCT/FR2007/000360 patent/WO2007099227A2/fr not_active Ceased
- 2007-02-28 JP JP2008556816A patent/JP5205282B2/ja not_active Expired - Fee Related
- 2007-02-28 US US12/281,104 patent/US8575105B2/en not_active Expired - Fee Related
- 2007-02-28 AT AT07731062T patent/ATE529124T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2643722A1 (fr) | 2007-09-07 |
| JP2009529001A (ja) | 2009-08-13 |
| FR2897780B1 (fr) | 2008-05-23 |
| US8575105B2 (en) | 2013-11-05 |
| EP1993587B1 (de) | 2011-10-19 |
| JP5205282B2 (ja) | 2013-06-05 |
| EP1993587A2 (de) | 2008-11-26 |
| FR2897780A1 (fr) | 2007-08-31 |
| CA2643722C (fr) | 2014-07-08 |
| WO2007099227A2 (fr) | 2007-09-07 |
| US20110294739A1 (en) | 2011-12-01 |
| WO2007099227A3 (fr) | 2007-10-18 |
| ES2376362T3 (es) | 2012-03-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |