ATE530670T1 - Verfahren zur vorhersage der ansprechempfindlichkeit auf tnf-blocker - Google Patents
Verfahren zur vorhersage der ansprechempfindlichkeit auf tnf-blockerInfo
- Publication number
- ATE530670T1 ATE530670T1 AT07789647T AT07789647T ATE530670T1 AT E530670 T1 ATE530670 T1 AT E530670T1 AT 07789647 T AT07789647 T AT 07789647T AT 07789647 T AT07789647 T AT 07789647T AT E530670 T1 ATE530670 T1 AT E530670T1
- Authority
- AT
- Austria
- Prior art keywords
- predicting
- responsibility
- tnf blockers
- genes
- patient
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102100040605 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase Human genes 0.000 abstract 1
- 101710181757 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase Proteins 0.000 abstract 1
- 102100034036 39S ribosomal protein L22, mitochondrial Human genes 0.000 abstract 1
- 102100023679 40S ribosomal protein S28 Human genes 0.000 abstract 1
- 102100040084 A-kinase anchor protein 9 Human genes 0.000 abstract 1
- 238000000018 DNA microarray Methods 0.000 abstract 1
- 102100039369 Epidermal growth factor receptor substrate 15 Human genes 0.000 abstract 1
- 102100031618 HLA class II histocompatibility antigen, DP beta 1 chain Human genes 0.000 abstract 1
- 108010045483 HLA-DPB1 antigen Proteins 0.000 abstract 1
- 101000711436 Homo sapiens 39S ribosomal protein L22, mitochondrial Proteins 0.000 abstract 1
- 101000623076 Homo sapiens 40S ribosomal protein S28 Proteins 0.000 abstract 1
- 101000890598 Homo sapiens A-kinase anchor protein 9 Proteins 0.000 abstract 1
- 101000812517 Homo sapiens Epidermal growth factor receptor substrate 15 Proteins 0.000 abstract 1
- 101000870945 Homo sapiens Ras guanyl-releasing protein 3 Proteins 0.000 abstract 1
- -1 PTNP12 Proteins 0.000 abstract 1
- 102100033450 Ras guanyl-releasing protein 3 Human genes 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 239000002981 blocking agent Substances 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Materials Using Thermal Means (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06290789A EP1857559A1 (de) | 2006-05-16 | 2006-05-16 | Verfahren zur Vorhersage der Sensivität gegenüber TNF-alpha-Blockern |
| PCT/IB2007/002373 WO2007135568A2 (en) | 2006-05-16 | 2007-05-15 | A METHOD FOR PREDICTING RESPONSIVENESS TO TNFα BLOCKING AGENTS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE530670T1 true ATE530670T1 (de) | 2011-11-15 |
Family
ID=36764554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07789647T ATE530670T1 (de) | 2006-05-16 | 2007-05-15 | Verfahren zur vorhersage der ansprechempfindlichkeit auf tnf-blocker |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7985549B2 (de) |
| EP (2) | EP1857559A1 (de) |
| AT (1) | ATE530670T1 (de) |
| CA (1) | CA2652087A1 (de) |
| DK (1) | DK2019872T3 (de) |
| ES (1) | ES2375865T3 (de) |
| WO (1) | WO2007135568A2 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2009013410A (es) * | 2007-06-08 | 2010-03-22 | Biogen Idec Inc | Biomarcadores para predecir capacidad de respuesta anti-tnf o sin capacidad de respuesta. |
| WO2009117791A2 (en) * | 2008-03-28 | 2009-10-01 | Katholieke Universiteit Leuven | Mucosal gene signatures |
| US20110177966A1 (en) * | 2008-06-12 | 2011-07-21 | Xavier Le Loet | method for predicting the response to a treatment with anakinra |
| ES2335381B1 (es) * | 2008-09-24 | 2011-02-28 | Fundacio Institut De Recerca De L'hospital Universitari Vall D'hebron | Metodo in vitro y kit para el pronostico o prediccion de la respuestapor parte de pacientes con artritis reumatoide al tratamiento con agentes bloqueantes del factor tnfalfa. |
| EP2192197A1 (de) * | 2008-11-27 | 2010-06-02 | Vereniging voor christelijk hoger onderwijs, wetenschappelijk onderzoek en patiëntenzorg | Vorhersage der klinischen Reaktion auf die Behandlung mit einem löslichen TNF-Antagonisten oder TNF oder ein TNF-Rezeptoragonist |
| BR112012004777A2 (pt) | 2009-09-03 | 2019-09-24 | Genentech Inc | métodos para tratar diagnósticar e monitorar artrite reumatoide |
| EP3409289B1 (de) | 2010-02-26 | 2020-09-30 | Novo Nordisk A/S | Stabile, antikörperhaltige zusammensetzungen |
| CN102918165A (zh) * | 2010-03-24 | 2013-02-06 | Tc园表达公司 | 患有炎症疾病的受试者对细胞因子靶向药物(CyTD)的早期反应或无反应预测的基因和基因组合 |
| RU2012153786A (ru) | 2010-05-28 | 2014-07-10 | Ново Нордиск А/С | Стабильные многодозовые композиции, содержащие антитело и консервант |
| WO2012118750A2 (en) | 2011-02-28 | 2012-09-07 | Genentech, Inc. | Biological markers and methods for predicting response to b-cell antagonists |
| EP3130921B1 (de) * | 2011-07-06 | 2018-09-12 | Nestec S.A. | Tests für den nachweis neutralisierender autoantikörper gegen biologische therapie mit tnf-alpha |
| KR20140124767A (ko) | 2012-02-10 | 2014-10-27 | 노보 노르디스크 에이/에스 | 염증성 질환 및 장애의 치료에 관한 방법 |
| HU230680B1 (hu) * | 2012-10-19 | 2017-08-28 | Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag | Diagnosztikai eljárás |
| US20140255393A1 (en) * | 2013-02-28 | 2014-09-11 | Nodality, Inc. | Compositions and methods for autoimmune disease |
| US20220364171A1 (en) * | 2018-11-23 | 2022-11-17 | Katholieke Universiteit Leuven | Predicting a treatment response in inflammatory bowel disease |
| EP4359567A4 (de) * | 2021-06-22 | 2025-06-11 | Scipher Medicine Corporation | Verfahren und systeme zur therapieüberwachung und versuchsausführung |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US196799A (en) | 1877-11-06 | Improvement in washing-machines | ||
| ATE537270T1 (de) * | 1997-10-30 | 2011-12-15 | Cold Spring Harbor Lab | Sondenanordnungen und deren verwendungen für verfahren zur dns-unterscheidung |
-
2006
- 2006-05-16 EP EP06290789A patent/EP1857559A1/de not_active Withdrawn
-
2007
- 2007-05-15 US US12/300,847 patent/US7985549B2/en not_active Expired - Fee Related
- 2007-05-15 ES ES07789647T patent/ES2375865T3/es active Active
- 2007-05-15 CA CA002652087A patent/CA2652087A1/en not_active Abandoned
- 2007-05-15 WO PCT/IB2007/002373 patent/WO2007135568A2/en not_active Ceased
- 2007-05-15 AT AT07789647T patent/ATE530670T1/de active
- 2007-05-15 EP EP07789647A patent/EP2019872B1/de not_active Not-in-force
- 2007-05-15 DK DK07789647.0T patent/DK2019872T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| US7985549B2 (en) | 2011-07-26 |
| US20090252740A1 (en) | 2009-10-08 |
| EP2019872A2 (de) | 2009-02-04 |
| WO2007135568A3 (en) | 2008-02-28 |
| WO2007135568A2 (en) | 2007-11-29 |
| CA2652087A1 (en) | 2007-11-29 |
| ES2375865T3 (es) | 2012-03-07 |
| DK2019872T3 (da) | 2012-01-16 |
| EP1857559A1 (de) | 2007-11-21 |
| EP2019872B1 (de) | 2011-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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