ATE530907T1 - Verfahren zur beurteilung der hemmungsaktivität von antikörpern gegen insulinartigen wachstumsfaktor-1-rezeptor - Google Patents
Verfahren zur beurteilung der hemmungsaktivität von antikörpern gegen insulinartigen wachstumsfaktor-1-rezeptorInfo
- Publication number
- ATE530907T1 ATE530907T1 AT08716004T AT08716004T ATE530907T1 AT E530907 T1 ATE530907 T1 AT E530907T1 AT 08716004 T AT08716004 T AT 08716004T AT 08716004 T AT08716004 T AT 08716004T AT E530907 T1 ATE530907 T1 AT E530907T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibitory activity
- assessing
- receptor
- growth factor
- antibodies against
- Prior art date
Links
- 230000002401 inhibitory effect Effects 0.000 title abstract 4
- 102100039688 Insulin-like growth factor 1 receptor Human genes 0.000 title 1
- 101710184277 Insulin-like growth factor 1 receptor Proteins 0.000 title 1
- 210000000265 leukocyte Anatomy 0.000 abstract 2
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 1
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 abstract 1
- 102000048143 Insulin-Like Growth Factor II Human genes 0.000 abstract 1
- 108090001117 Insulin-Like Growth Factor II Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07003948 | 2007-02-27 | ||
| PCT/EP2008/001457 WO2008104344A1 (en) | 2007-02-27 | 2008-02-25 | Method for the assessment of the inhibitory activity of antibodies against insulin-like growth factor i receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE530907T1 true ATE530907T1 (de) | 2011-11-15 |
Family
ID=38108609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08716004T ATE530907T1 (de) | 2007-02-27 | 2008-02-25 | Verfahren zur beurteilung der hemmungsaktivität von antikörpern gegen insulinartigen wachstumsfaktor-1-rezeptor |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100323373A1 (de) |
| EP (1) | EP2126565B1 (de) |
| JP (1) | JP2010517024A (de) |
| CN (1) | CN101617228A (de) |
| AT (1) | ATE530907T1 (de) |
| CA (1) | CA2677901A1 (de) |
| ES (1) | ES2375242T3 (de) |
| WO (1) | WO2008104344A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010540960A (ja) | 2007-10-03 | 2010-12-24 | オーエスアイ・ファーマスーティカルズ・インコーポレーテッド | インスリン様成長因子−１受容体キナーゼ阻害剤に対する抗癌反応を予測する生物学的マーカー |
| WO2009045389A2 (en) | 2007-10-03 | 2009-04-09 | Osi Pharmaceuticals, Inc. | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors |
| WO2012149014A1 (en) | 2011-04-25 | 2012-11-01 | OSI Pharmaceuticals, LLC | Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5238808A (en) | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US5068088A (en) | 1988-11-03 | 1991-11-26 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescent measurements |
| ZA898290B (en) | 1988-11-03 | 1991-06-26 | Igen Inc | Electrochemiluminescent assays |
| IL100866A (en) | 1991-02-06 | 1995-10-31 | Igen Inc | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets |
| ME00502B (me) * | 2001-01-05 | 2011-10-10 | Amgen Fremont Inc | Antitjela za insulinu sličan receptor faktora i rasta |
| ES2383014T3 (es) | 2003-04-02 | 2012-06-15 | F. Hoffmann-La Roche Ag | Anticuerpos contra el factor I de crecimiento similar a insulina y usos de los mismos |
| AR046071A1 (es) | 2003-07-10 | 2005-11-23 | Hoffmann La Roche | Anticuerpos contra el receptor i del factor de crecimiento de tipo insulinico y los usos de los mismos |
-
2008
- 2008-02-25 AT AT08716004T patent/ATE530907T1/de not_active IP Right Cessation
- 2008-02-25 EP EP08716004A patent/EP2126565B1/de not_active Not-in-force
- 2008-02-25 US US12/528,396 patent/US20100323373A1/en not_active Abandoned
- 2008-02-25 WO PCT/EP2008/001457 patent/WO2008104344A1/en not_active Ceased
- 2008-02-25 ES ES08716004T patent/ES2375242T3/es active Active
- 2008-02-25 CN CN200880005371A patent/CN101617228A/zh active Pending
- 2008-02-25 CA CA002677901A patent/CA2677901A1/en not_active Abandoned
- 2008-02-25 JP JP2009546703A patent/JP2010517024A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2126565A1 (de) | 2009-12-02 |
| ES2375242T3 (es) | 2012-02-28 |
| JP2010517024A (ja) | 2010-05-20 |
| WO2008104344A1 (en) | 2008-09-04 |
| EP2126565B1 (de) | 2011-10-26 |
| CN101617228A (zh) | 2009-12-30 |
| US20100323373A1 (en) | 2010-12-23 |
| CA2677901A1 (en) | 2008-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |