ATE532506T1 - Neue aromatische verbindungen und ihre verwendung in medizinischen anwendungen - Google Patents

Neue aromatische verbindungen und ihre verwendung in medizinischen anwendungen

Info

Publication number
ATE532506T1
ATE532506T1 AT06792185T AT06792185T ATE532506T1 AT E532506 T1 ATE532506 T1 AT E532506T1 AT 06792185 T AT06792185 T AT 06792185T AT 06792185 T AT06792185 T AT 06792185T AT E532506 T1 ATE532506 T1 AT E532506T1
Authority
AT
Austria
Prior art keywords
aromatic compounds
medical applications
new aromatic
formulas
pharmaceutically acceptable
Prior art date
Application number
AT06792185T
Other languages
English (en)
Inventor
Ewald Aydt
Remo Kranich
Anke Busemann
Original Assignee
Revotar Biopharmaceuticals Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Revotar Biopharmaceuticals Ag filed Critical Revotar Biopharmaceuticals Ag
Application granted granted Critical
Publication of ATE532506T1 publication Critical patent/ATE532506T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
AT06792185T 2005-09-20 2006-09-20 Neue aromatische verbindungen und ihre verwendung in medizinischen anwendungen ATE532506T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05020510A EP1764093A1 (de) 2005-09-20 2005-09-20 Neue aromatische Verbindungen und deren medizinische Verwendung
PCT/EP2006/009154 WO2007039113A1 (en) 2005-09-20 2006-09-20 Novel aromatic compounds and their use in medical applications

Publications (1)

Publication Number Publication Date
ATE532506T1 true ATE532506T1 (de) 2011-11-15

Family

ID=35717680

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06792185T ATE532506T1 (de) 2005-09-20 2006-09-20 Neue aromatische verbindungen und ihre verwendung in medizinischen anwendungen

Country Status (5)

Country Link
US (2) US7923473B2 (de)
EP (2) EP1764093A1 (de)
JP (1) JP2009508901A (de)
AT (1) ATE532506T1 (de)
WO (1) WO2007039113A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1577289A1 (de) * 2004-03-18 2005-09-21 Revotar Biopharmaceuticals AG Nicht-glykosylierte/-glykosidische/-peptidische keine Moleküle als Selektininhibitoren für die Behandlung entzündlicher Erkrankungen.
EP1764095A1 (de) * 2005-09-20 2007-03-21 Revotar Biopharmaceuticals AG Neue Nitrocatecholderivate mit Selectin-Ligand-Activität
EP1764094A1 (de) * 2005-09-20 2007-03-21 Revotar Biopharmaceuticals AG Neuartige multi-zyklische Verbindungen und deren Verwendung
EP1764093A1 (de) 2005-09-20 2007-03-21 Revotar Biopharmaceuticals AG Neue aromatische Verbindungen und deren medizinische Verwendung
EP1764096A1 (de) 2005-09-20 2007-03-21 Revotar Biopharmaceuticals AG Neue Phloroglucinolderivate mit Selectin-Ligand-Aktivität
CA2684105C (en) 2007-05-03 2011-09-06 Pfizer Limited Pyridine derivatives

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4363813A (en) * 1979-07-09 1982-12-14 Kureha Kagaku Kogyo Kabushiki Kaisha 2-(3,4,5-Trimethoxyphenyl)-4,5-disubstituted thiazoles
JPS58156932A (ja) * 1982-03-11 1983-09-19 Fuji Photo Film Co Ltd ハロゲン化銀カラ−写真感光材料
US4757084A (en) * 1984-02-29 1988-07-12 Merck & Co., Inc. 2,5-diaryl tetrahydrothiophenes and analogs thereof as PAF-antagonists
GB2238047B (en) 1989-11-03 1993-02-10 Orion Yhtymae Oy Stable polymorphic form of (e)-n,n-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide and the process for its preparation
EP0465122A1 (de) * 1990-06-29 1992-01-08 Merck & Co. Inc. Verfahren zur Herstellung von 2,5-Diaryl-tetrahydrofuranen und deren Analogen, welche als PAF-Antagonisten verwendbar sind
US5374772A (en) 1992-12-08 1994-12-20 Hoffmann-Laroche Inc. Substituted benzoic acids, inhibitors of phospholipases A2
US5444050A (en) 1994-04-29 1995-08-22 Texas Biotechnology Corporation Binding of E-selectin or P-selectin to sialyl Lewisx or sialyl-Lewisa
UA52607C2 (uk) 1995-06-29 2003-01-15 Тексіс Байотекнолоджі Корпорейшн Похідні біфенілів, фармацевтична композиція на їх основі та спосіб інгібування (варіанти)
KR19990028543A (ko) 1995-06-29 1999-04-15 한스 루돌프 하우스, 헨리테 브룬너, 베아트리체 귄터 시알릴-루이스 ｘ 및 시알릴-루이스 ａ의 유사체로서의 디글리코실화 1,2-디올
JPH10306024A (ja) * 1997-03-07 1998-11-17 Kissei Pharmaceut Co Ltd 糸球体疾患の予防および治療剤
FR2761066B1 (fr) * 1997-03-24 2000-11-24 Sod Conseils Rech Applic Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
WO1999005312A1 (fr) * 1997-07-23 1999-02-04 Tokuyama Corporation Procede de determination de parametres de coagulation
WO1999029706A2 (en) 1997-12-08 1999-06-17 Glycomed Incorporated DISALICYLATE ANALOG BASED SIALYL LEWISx MIMETICS
AU1804299A (en) * 1997-12-08 1999-06-28 Glycomed Incorporated Sialyl lewis x and sialyl lewis a glycomimetics
AU3538699A (en) 1998-05-18 1999-12-06 Eisai Co. Ltd. Novel physiologically active substances
WO2000033836A1 (en) 1998-12-04 2000-06-15 Ontogen Corporation 5-membered heterocycles for the treatment of human diseases involving modulators of selectins
US6248790B1 (en) 2000-06-29 2001-06-19 Parker Hughes Institute Treatment of inflammation with 2,4,6-trihydroxy-alpha-rho-methoxyphenylacetophenone, or its pharmaceutically acceptable derivatives
US6432957B1 (en) 2001-06-29 2002-08-13 Kowa Co., Ltd. Piperazine derivative
JP4425628B2 (ja) 2001-07-23 2010-03-03 ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド 細胞保護化合物、薬学的処方物および美容用処方物、ならびに方法
JP2003055369A (ja) 2001-08-06 2003-02-26 Univ Nihon 新規なフロログルシノール誘導体、及びこれを用いた組成物、抗アレルギー剤
WO2003075905A1 (es) * 2002-03-14 2003-09-18 Bobel 246, S.L. Uso de derivados de fenoles 2,4-disubstituidos como inhibidores de la expresion de l-selectinas y de la isoforma inductible de la sintasa del oxido nitrico
JP4266348B2 (ja) * 2002-03-27 2009-05-20 カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ Ｄｄｑの媒介するジヒドロアサロンの二量体化によるネオリグナンの生成
WO2003097658A2 (en) 2002-05-16 2003-11-27 Glycomimetics, Inc. Compounds and methods for inhibiting selectin-mediated function
WO2004018502A1 (en) 2002-08-09 2004-03-04 Yamanouchi Europe B.V. Compounds binding to p-selectin
US20040110802A1 (en) * 2002-08-23 2004-06-10 Atli Thorarensen Antibacterial benzoic acid derivatives
EP1569907B1 (de) * 2002-12-13 2016-03-09 YM BioSciences Australia Pty Ltd Nicotinamid-basierte kinasehemmer
WO2004056774A2 (en) * 2002-12-19 2004-07-08 Neurogen Corporation Substituted biphenyl-4-carboxylic acid arylamide analogues as capsaicin receptor modulators
WO2004112837A1 (ja) 2003-05-23 2004-12-29 Hisamitsu Pharmaceutical Co., Inc. 非ステロイド系消炎鎮痛剤含有外用経皮製剤およびインターロイキン－１α生成抑制剤
EP1481669A1 (de) 2003-05-30 2004-12-01 Yamanouchi Pharmaceutical Co. Ltd. Verwendung von Polyhydroxyphenolen und Polyphenolen zur Modulation der P-Selektin Aktivität
MXPA06003951A (es) * 2003-10-07 2006-06-27 Renovis Inc Derivados de amida como ligandos del canal de ion y composiciones farmaceuticas y sus metodos de uso.
EP1577289A1 (de) * 2004-03-18 2005-09-21 Revotar Biopharmaceuticals AG Nicht-glykosylierte/-glykosidische/-peptidische keine Moleküle als Selektininhibitoren für die Behandlung entzündlicher Erkrankungen.
EP1764093A1 (de) 2005-09-20 2007-03-21 Revotar Biopharmaceuticals AG Neue aromatische Verbindungen und deren medizinische Verwendung
EP1764096A1 (de) 2005-09-20 2007-03-21 Revotar Biopharmaceuticals AG Neue Phloroglucinolderivate mit Selectin-Ligand-Aktivität
EP1764094A1 (de) * 2005-09-20 2007-03-21 Revotar Biopharmaceuticals AG Neuartige multi-zyklische Verbindungen und deren Verwendung
EP1764095A1 (de) * 2005-09-20 2007-03-21 Revotar Biopharmaceuticals AG Neue Nitrocatecholderivate mit Selectin-Ligand-Activität

Also Published As

Publication number Publication date
EP1764093A1 (de) 2007-03-21
US7923473B2 (en) 2011-04-12
EP1940372A1 (de) 2008-07-09
US20080207639A1 (en) 2008-08-28
US20110152291A1 (en) 2011-06-23
EP1940372B1 (de) 2011-11-09
US8394835B2 (en) 2013-03-12
WO2007039113A1 (en) 2007-04-12
JP2009508901A (ja) 2009-03-05

Similar Documents

Publication Publication Date Title
AU2006299184A8 (en) Novel nitrocatechol derivatives having selectin ligand activity
GEP20146033B (en) N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides usage as wnt signaling modulators
NO20081231L (no) Kondenserte heterocykliske forbindelser anvendbare som kinasemodulatorer
GEP20115241B (en) Indole compound
FI20030958A0 (fi) Uusia yhdisteitä
MX2010009752A (es) Compuestos de oxadiazoantraceno para el tratamiento de diabetes.
NO20090321L (no) Anvendelse av substituerte 2-aminotyetraliner for produksjon av et medikament for forhindringen, lettingen og/eller behandlingen av diverse typer smerte
UA95766C2 (ru) Производные терфенила для лечения болезни альцгеймера
BR0311494A (pt) Novos indóis substituìdos
MX2008012399A (es) Modulacion de cinasa de ceramida.
MX2009000657A (es) Composiciones y metodos para el tratamiento de mucositis.
JO2853B1 (en) Sulfonamides as TRPM8 organizations
WO2007067711A3 (en) Certain chemical entities, compositions, and methods for modulating trpv1
CY1115247T1 (el) Ενωσεις συμπυκνωμενων δακτυλιων και χρηση αυτων
WO2007039112A8 (en) Novel phloroglucinol derivatives having selectin ligand activity
MY148538A (en) Novel 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions
MY148953A (en) Substituted biphenyl carboxylic acids and derivatives thereof
MY158069A (en) Tricyclic compound and pharmaceutical use thereof
CY1111857T1 (el) Κρυσταλλικη βαση trans-1-((1r,3s)-6-xλωpo-3-φαινυλινδαν-1-υλο)-3,3-διμεθυλοπιπεραζινης
ATE532506T1 (de) Neue aromatische verbindungen und ihre verwendung in medizinischen anwendungen
UY28006A1 (es) Agonistas ppar quirales
DE602006010738D1 (de) Pyrroloä2,3-cüpyridinderivate
NO20090927L (no) Behandling av mykobakterielle infeksjoner med cyklipostiner
WO2007039111A3 (en) Novel multi-cyclic compounds and their use
EP2045258A4 (de) 3ý-ETHYNYLCYTIDINDERIVAT