ATE53299T1 - Blutstillende irrigationsloesung. - Google Patents

Blutstillende irrigationsloesung.

Info

Publication number: ATE53299T1
Authority: AT; Austria
Prior art keywords: solution; hemostatic; irrigation solution; protamine; norepinephrine
Prior art date: 1985-08-06

Application number

AT86305933T

Other languages

English (en)

Inventor

Gerald M Lemole

Original Assignee

Gerald M Lemole

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-06

Filing date

1986-08-01

Publication date

1990-06-15

1986-08-01 Application filed by Gerald M Lemole filed Critical Gerald M Lemole

1990-06-15 Application granted granted Critical

1990-06-15 Publication of ATE53299T1 publication Critical patent/ATE53299T1/de

Links

230000002439 hemostatic effect Effects 0.000 title 1
229940113601 irrigation solution Drugs 0.000 title 1
SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 abstract 1
SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 abstract 1
UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 1
102000007327 Protamines Human genes 0.000 abstract 1
108010007568 Protamines Proteins 0.000 abstract 1
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
108090000190 Thrombin Proteins 0.000 abstract 1
229960002684 aminocaproic acid Drugs 0.000 abstract 1
239000001110 calcium chloride Substances 0.000 abstract 1
229910001628 calcium chloride Inorganic materials 0.000 abstract 1
229960002713 calcium chloride Drugs 0.000 abstract 1
230000015271 coagulation Effects 0.000 abstract 1
238000005345 coagulation Methods 0.000 abstract 1
230000002708 enhancing effect Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229960002748 norepinephrine Drugs 0.000 abstract 1
SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 abstract 1
229940048914 protamine Drugs 0.000 abstract 1
229960004072 thrombin Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4833—Thrombin (3.4.21.5)

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT86305933T 1985-08-06 1986-08-01 Blutstillende irrigationsloesung. ATE53299T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/763,056 US4637815A (en)	1985-08-06	1985-08-06	Irrigational hemostatic solution
EP86305933A EP0211629B1 (de)	1985-08-06	1986-08-01	Blutstillende Irrigationslösung

Publications (1)

Publication Number	Publication Date
ATE53299T1 true ATE53299T1 (de)	1990-06-15

Family

ID=25066769

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86305933T ATE53299T1 (de)	1985-08-06	1986-08-01	Blutstillende irrigationsloesung.

Country Status (5)

Country	Link
US (1)	US4637815A (de)
EP (1)	EP0211629B1 (de)
JP (1)	JPS6259222A (de)
AT (1)	ATE53299T1 (de)
DE (1)	DE3671700D1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5053006A (en) *	1988-04-19	1991-10-01	Watson Brant D	Method for the permanent occlusion of arteries
EP0365705A1 (de) *	1988-10-26	1990-05-02	Zentralna Problemna Laboratoria Po Kryobiologia I Lyophilisazia	Biopräparat zur Behandlung von Wunden
US5171217A (en) *	1991-02-28	1992-12-15	Indiana University Foundation	Method for delivery of smooth muscle cell inhibitors
CA2175203A1 (en) *	1993-11-03	1995-05-11	Thaddeus P. Pruss	Hemostatic patch
US5681278A (en) *	1994-06-23	1997-10-28	Cormedics Corp.	Coronary vasculature treatment method
KR100517210B1 (ko) *	1994-12-12	2006-06-07	오메로스 코포레이션	통증,염증및경련억제용관주용액
JPH10510540A (ja) *	1994-12-12	1998-10-13	オメロスメディカルシステムズ，インコーポレーテッド	灌注用溶液並びに疼痛、炎症及びけいれんの抑制法
WO1996019233A2 (en) *	1994-12-12	1996-06-27	Omeros Medical Systems, Inc.	Irrigation solution and method for inhibition of pain, inflammation and spasm
WO1996040033A1 (en) *	1995-06-07	1996-12-19	Clarion Pharmaceuticals Inc.	Non-biological patch for hemostasis
DE10258954A1 (de) *	2002-12-16	2004-07-08	Langer, Hans-Georg	Blutungsstillende Wundversorgung
AU2006247077A1 (en) *	2005-05-18	2006-11-23	Pulmatrix Inc.	Formulations for alteration of biophysical properties of mucosal lining
US8551961B2 (en) *	2005-05-25	2013-10-08	Massachusetts Institute Of Technology	Localized delivery of cardiac inotropic agents
US8057426B2 (en) *	2007-01-03	2011-11-15	Medtronic Vascular, Inc.	Devices and methods for injection of multiple-component therapies
JP5546455B2 (ja) *	2007-10-02	2014-07-09	リグスホスピタル	交感神経系α‐および／またはβ‐アドレナリン受容体に対してアゴニスト作用を有する交感神経作動薬の血餅強度改善に関連した全身的止血促進効果
EP2331085A1 (de) *	2008-08-26	2011-06-15	Massachusetts Institute of Technology	Vorrichtungen und systeme zur lokalen verabreichung von inotropen mitteln an das epikard
ES2625260T5 (es)	2009-03-26	2020-07-29	Pulmatrix Operating Co Inc	Formulaciones de polvo seco y métodos para el tratamiento de enfermedades pulmonares
DK2315580T3 (da) *	2009-03-26	2012-04-10	Pulmatrix Inc	Farmaceutiske formuleringer og fremgangsmåder til behandling af luftvejsinfektioner
CN103200938B (zh)	2010-08-30	2018-07-31	普马特里克斯营业公司	干燥粉末配方及用于治疗肺部疾病的方法
WO2012030645A1 (en)	2010-08-30	2012-03-08	Pulmatrix, Inc.	Respirably dry powder comprising calcium lactate, sodium chloride and leucine
PT3470057T (pt)	2010-09-29	2021-12-03	Pulmatrix Operating Co Inc	Pós secos catiónicos compreendendo sais de magnésio
BR112013007304B1 (pt)	2010-09-29	2021-12-14	Pulmatrix, Inc.	Pós secos de cátion de metal monovalente para inalação
CN107596518B (zh)	2012-02-29	2021-04-23	普马特里克斯营业公司	可吸入干粉剂
AU2014248455B2 (en)	2013-04-01	2018-12-06	Pulmatrix Operating Company, Inc.	Tiotropium dry powders
KR102665892B1 (ko) *	2015-11-08	2024-05-16	옴릭스 바이오파머슈티컬스 리미티드	셀룰로오스-기반의 짧은 섬유 및 긴 섬유의 지혈 혼합물
RU2741304C2 (ru) *	2015-11-08	2021-01-25	Омрикс Биофармасьютикалс Лтд.	Гемостатическая композиция
CN116212008A (zh) *	2023-03-15	2023-06-06	武汉康宁美生物科技有限公司	一种伤口创面消毒凝胶及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2532348A (en) *	1946-12-12	1950-12-05	Szent-Gyorgyi Albert	Blood clotting preparation
CH303082A (de) *	1950-12-18	1954-11-15	Hoechst Ag	Verfahren zur Herstellung eines haltbaren Thrombinpräparates von gesteigerter Wirksamkeit.

1985
- 1985-08-06 US US06/763,056 patent/US4637815A/en not_active Expired - Fee Related
1986
- 1986-08-01 AT AT86305933T patent/ATE53299T1/de not_active IP Right Cessation
- 1986-08-01 EP EP86305933A patent/EP0211629B1/de not_active Expired - Lifetime
- 1986-08-01 DE DE8686305933T patent/DE3671700D1/de not_active Expired - Lifetime
- 1986-08-06 JP JP61184971A patent/JPS6259222A/ja active Granted

Also Published As

Publication number	Publication date
JPH0359045B2 (de)	1991-09-09
EP0211629A1 (de)	1987-02-25
JPS6259222A (ja)	1987-03-14
US4637815A (en)	1987-01-20
EP0211629B1 (de)	1990-06-06
DE3671700D1 (de)	1990-07-12

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Legal Events

Date	Code	Title	Description
1990-11-15	UEP	Publication of translation of european patent specification
1995-05-15	REN	Ceased due to non-payment of the annual fee