ATE53299T1 - Blutstillende irrigationsloesung. - Google Patents

Blutstillende irrigationsloesung.

Info

Publication number: ATE53299T1
Authority: AT; Austria
Prior art keywords: solution; hemostatic; irrigation solution; protamine; norepinephrine
Prior art date: 1985-08-06

Application number

AT86305933T

Other languages

English (en)

Inventor

Gerald M Lemole

Original Assignee

Gerald M Lemole

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-06

Filing date

1986-08-01

Publication date

1990-06-15

1986-08-01 Application filed by Gerald M Lemole filed Critical Gerald M Lemole

1990-06-15 Application granted granted Critical

1990-06-15 Publication of ATE53299T1 publication Critical patent/ATE53299T1/de

Links

230000002439 hemostatic effect Effects 0.000 title 1
229940113601 irrigation solution Drugs 0.000 title 1
SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 abstract 1
SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 abstract 1
UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 1
102000007327 Protamines Human genes 0.000 abstract 1
108010007568 Protamines Proteins 0.000 abstract 1
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
108090000190 Thrombin Proteins 0.000 abstract 1
229960002684 aminocaproic acid Drugs 0.000 abstract 1
239000001110 calcium chloride Substances 0.000 abstract 1
229910001628 calcium chloride Inorganic materials 0.000 abstract 1
229960002713 calcium chloride Drugs 0.000 abstract 1
230000015271 coagulation Effects 0.000 abstract 1
238000005345 coagulation Methods 0.000 abstract 1
230000002708 enhancing effect Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229960002748 norepinephrine Drugs 0.000 abstract 1
SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 abstract 1
229940048914 protamine Drugs 0.000 abstract 1
229960004072 thrombin Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4833—Thrombin (3.4.21.5)

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT86305933T 1985-08-06 1986-08-01 Blutstillende irrigationsloesung. ATE53299T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/763,056 US4637815A (en)	1985-08-06	1985-08-06	Irrigational hemostatic solution
EP86305933A EP0211629B1 (de)	1985-08-06	1986-08-01	Blutstillende Irrigationslösung

Publications (1)

Publication Number	Publication Date
ATE53299T1 true ATE53299T1 (de)	1990-06-15

Family

ID=25066769

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86305933T ATE53299T1 (de)	1985-08-06	1986-08-01	Blutstillende irrigationsloesung.

Country Status (5)

Country	Link
US (1)	US4637815A (de)
EP (1)	EP0211629B1 (de)
JP (1)	JPS6259222A (de)
AT (1)	ATE53299T1 (de)
DE (1)	DE3671700D1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5053006A (en) *	1988-04-19	1991-10-01	Watson Brant D	Method for the permanent occlusion of arteries
EP0365705A1 (de) *	1988-10-26	1990-05-02	Zentralna Problemna Laboratoria Po Kryobiologia I Lyophilisazia	Biopräparat zur Behandlung von Wunden
US5171217A (en) *	1991-02-28	1992-12-15	Indiana University Foundation	Method for delivery of smooth muscle cell inhibitors
AU1086795A (en) *	1993-11-03	1995-05-23	Clarion Pharmaceuticals, Inc.	Hemostatic patch
US5681278A (en) *	1994-06-23	1997-10-28	Cormedics Corp.	Coronary vasculature treatment method
WO1996019233A2 (en) *	1994-12-12	1996-06-27	Omeros Medical Systems, Inc.	Irrigation solution and method for inhibition of pain, inflammation and spasm
KR100517210B1 (ko) *	1994-12-12	2006-06-07	오메로스 코포레이션	통증,염증및경련억제용관주용액
WO1996040033A1 (en) *	1995-06-07	1996-12-19	Clarion Pharmaceuticals Inc.	Non-biological patch for hemostasis
BR9509985A (pt) *	1995-12-12	1998-11-03	Omeros Med Sys Inc	Solução para irrigação e método para inibição de dor inflamação e esparmo
DE10258954A1 (de) *	2002-12-16	2004-07-08	Langer, Hans-Georg	Blutungsstillende Wundversorgung
EP1906922A2 (de) *	2005-05-18	2008-04-09	Pulmatrix, Inc.	Formulierungen zur veränderung biophysikalischer eigenschaften der schleimhautauskleidung
US8551961B2 (en) *	2005-05-25	2013-10-08	Massachusetts Institute Of Technology	Localized delivery of cardiac inotropic agents
US8057426B2 (en) *	2007-01-03	2011-11-15	Medtronic Vascular, Inc.	Devices and methods for injection of multiple-component therapies
EP2207537B1 (de) *	2007-10-02	2017-06-14	Fremont Group Ltd	Systemische hämostasefördernde wirkung von sympathikomimetika mit agonistischen wirkungen auf die alpha-adrenergen und/oder beta-adrenergen rezeptoren des sympathischen nervensystems im zusammenhang mit verbesserter gerinnselstärke
EP2331085A1 (de) *	2008-08-26	2011-06-15	Massachusetts Institute of Technology	Vorrichtungen und systeme zur lokalen verabreichung von inotropen mitteln an das epikard
MX2011009959A (es) *	2009-03-26	2012-01-27	Pulmatrix Inc	Formulaciones farmaceuticas y metodos para el tratamiento de enfermedades del tracto respiratorio.
MX354829B (es)	2009-03-26	2018-03-22	Pulmatrix Operating Co Inc	Formulaciones de polvo seco y metodos para el tratamiento de enfermedades pulmonares.
EP2464346A1 (de)	2010-08-30	2012-06-20	Pulmatrix, Inc.	Behandlung zystischer fibrose mit calciumlactat, leukin und natriumchlorid in einem einatembaren trockenpulver
CA2809666C (en)	2010-08-30	2020-09-22	Michael M. Lipp	Dry powder formulations and methods for treating pulmonary diseases
RU2640921C2 (ru)	2010-09-29	2018-01-12	Пулмэтрикс, Инк.	Катионы одновалентных металлов сухих порошков для ингаляций
AU2011314007B2 (en)	2010-09-29	2017-01-19	Pulmatrix, Inc.	Cationic dry powders
JP2015509788A (ja)	2012-02-29	2015-04-02	パルマトリックス，インコーポレイテッド	吸入に適した乾燥粉末
CA2907566C (en)	2013-04-01	2023-08-22	Pulmatrix, Inc.	Tiotropium dry powders
JP6862441B2 (ja) *	2015-11-08	2021-04-21	オムリックス・バイオファーマシューティカルズ・リミテッドＯｍｒｉｘＢｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓＬｔｄ．	セルロース系短尺繊維及び長尺繊維の止血混合物
MX383001B (es) *	2015-11-08	2025-03-13	Omrix Biopharmaceuticals Ltd	Composicion hemostatica.
CN116212008A (zh) *	2023-03-15	2023-06-06	武汉康宁美生物科技有限公司	一种伤口创面消毒凝胶及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2532348A (en) *	1946-12-12	1950-12-05	Szent-Gyorgyi Albert	Blood clotting preparation
CH303082A (de) *	1950-12-18	1954-11-15	Hoechst Ag	Verfahren zur Herstellung eines haltbaren Thrombinpräparates von gesteigerter Wirksamkeit.

1985
- 1985-08-06 US US06/763,056 patent/US4637815A/en not_active Expired - Fee Related
1986
- 1986-08-01 EP EP86305933A patent/EP0211629B1/de not_active Expired - Lifetime
- 1986-08-01 DE DE8686305933T patent/DE3671700D1/de not_active Expired - Lifetime
- 1986-08-01 AT AT86305933T patent/ATE53299T1/de not_active IP Right Cessation
- 1986-08-06 JP JP61184971A patent/JPS6259222A/ja active Granted

Also Published As

Publication number	Publication date
DE3671700D1 (de)	1990-07-12
EP0211629A1 (de)	1987-02-25
US4637815A (en)	1987-01-20
JPH0359045B2 (de)	1991-09-09
JPS6259222A (ja)	1987-03-14
EP0211629B1 (de)	1990-06-06

Legal Events

Date	Code	Title	Description
1990-11-15	UEP	Publication of translation of european patent specification
1995-05-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE3671700D1 (de)	1990-07-12	Blutstillende irrigationsloesung.
Green Jr et al.	1978	Effect of acid and pepsin on blood coagulation and platelet aggregation: a possible contributor to prolonged gastroduodenal mucosal hemorrhage
PT96103A (pt)	1991-09-30	Processo para a preparacao de proteinas fibrinoliticas e anti-tromboticas activaveis
ATE74379T1 (de)	1992-04-15	Peptidplasminogenaktivatoren.
ES2168461T3 (es)	2002-06-16	Inhibidores de trombina basados en la secuencia del amino acido de la hirudina.
FR2588189B1 (fr)	1988-12-02	Composition pharmaceutique de type a transition de phase liquide-gel
DK76085D0 (da)	1985-02-19	Antiinflammatoriske forbindelser og farmaceutiske midler indeholdendeforbindelserne
DE68923298D1 (de)	1995-08-03	Gewebe-plasminogenaktivator mit zymogenen oder fibrinspezifischen eigenschaften.
DK0691858T3 (da)	2000-05-08	Tokomponent fibrinklæber
ATE65185T1 (de)	1991-08-15	Thrombolytische zusammensetzung und verfahren zu deren herstellung.
SE8701921L (sv)	1987-11-13	Ny farmaceutisk anvendning
EP0230945A3 (en)	1988-03-23	Thrombin-binding substance and process for preparing thethrombin-binding substance and process for preparing the same same
ATE108206T1 (de)	1994-07-15	Gewebe-plasminogenaktivator.
ATE63750T1 (de)	1991-06-15	Peptid, dessen herstellung und benutzung.
MX9200882A (es)	1992-09-01	Preparacion de factor ix.
ATE235912T1 (de)	2003-04-15	Bradikininanaloge als selektive thrombininhibitoren
Furlan et al.	1983	Inhibition of fibrin polymerization by fragment D is affected by calcium, Gly-Pro-Arg and Gly-His-Arg
ES8607734A1 (es)	1986-06-01	Procedimiento para producir un preparado farmaceutico desti-nado a aplicacion por via topica
ES2177646T3 (es)	2002-12-16	Procedimientos para el tratamiento de los trastornos hemorragicos.
DE3689927D1 (de)	1994-07-28	Reagens und Verfahren.
DE59005355D1 (de)	1994-05-19	Dialysier- und Spüllösung zur intraperitonealen Verarbreichung.
ATE58521T1 (de)	1990-12-15	Lysinsalz der 4-biphenylessigsaeure und es enthaltende augenheilmittel.
DE3888619D1 (de)	1994-04-28	Modifizierter Gewebeplasminogenaktivator.
ATE125294T1 (de)	1995-08-15	Polypeptid-verbindungen.
EP0386240A4 (en)	1990-10-24	Novel polypeptide compounds