ATE533859T1 - MARKER FÜR NIERENTRANSPLANTATABSTOßUNG UND NIERENSCHÄDEN - Google Patents

MARKER FÜR NIERENTRANSPLANTATABSTOßUNG UND NIERENSCHÄDEN

Info

Publication number
ATE533859T1
ATE533859T1 AT07253514T AT07253514T ATE533859T1 AT E533859 T1 ATE533859 T1 AT E533859T1 AT 07253514 T AT07253514 T AT 07253514T AT 07253514 T AT07253514 T AT 07253514T AT E533859 T1 ATE533859 T1 AT E533859T1
Authority
AT
Austria
Prior art keywords
kidney
markers
transplant rejection
damage
renal
Prior art date
Application number
AT07253514T
Other languages
English (en)
Inventor
Stefan Kienle
Richard Joubert
Original Assignee
Electrophoretics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Electrophoretics Ltd filed Critical Electrophoretics Ltd
Application granted granted Critical
Publication of ATE533859T1 publication Critical patent/ATE533859T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/24Immunology or allergic disorders
    • G01N2800/245Transplantation related diseases, e.g. graft versus host disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT07253514T 2006-09-05 2007-09-05 MARKER FÜR NIERENTRANSPLANTATABSTOßUNG UND NIERENSCHÄDEN ATE533859T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0617429.6A GB0617429D0 (en) 2006-09-05 2006-09-05 Markers of renal transplant rejection and renal damage

Publications (1)

Publication Number Publication Date
ATE533859T1 true ATE533859T1 (de) 2011-12-15

Family

ID=37232368

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07253514T ATE533859T1 (de) 2006-09-05 2007-09-05 MARKER FÜR NIERENTRANSPLANTATABSTOßUNG UND NIERENSCHÄDEN

Country Status (6)

Country Link
US (2) US8021895B2 (de)
EP (2) EP1905846B1 (de)
AT (1) ATE533859T1 (de)
CA (1) CA2600168A1 (de)
ES (1) ES2379430T3 (de)
GB (1) GB0617429D0 (de)

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US9000134B2 (en) * 2007-05-11 2015-04-07 Wallace B. Haigh Reagent and kit for early diagnosis of kidney disease
WO2009124403A1 (en) * 2008-04-10 2009-10-15 The University Of British Columbia Methods of diagnosing chronic cardiac allograft rejection
CN102119224A (zh) * 2008-05-30 2011-07-06 不列颠哥伦比亚大学 使用基因组或蛋白质组表达图谱诊断肾同种异体移植物的排斥的方法
EP2743702B1 (de) * 2008-08-28 2017-08-09 Astute Medical, Inc. Verfahren und Zusammensetzungen zur Diagnose und Prognose von Nierenläsion und Niereninsuffizienz
JP5947544B2 (ja) 2008-08-29 2016-07-06 アスチュート メディカル,インコーポレイテッド 腎損傷および腎不全の診断および予後のための方法および組成物
MX2011004174A (es) 2008-10-21 2011-09-27 Astute Medical Inc Metodos y composiciones para diagnosis y prognosis de lesion renal e insuficiencia renal.
CN102246038B (zh) * 2008-10-21 2014-06-18 阿斯图特医药公司 用于诊断和预后肾损伤和肾衰竭的方法和组合物
WO2010054389A1 (en) 2008-11-10 2010-05-14 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
KR20110097850A (ko) * 2008-11-22 2011-08-31 아스튜트 메디컬 인코포레이티드 신손상 및 신부전의 진단 및 예후 예측을 위한 방법 및 조성물
US9229010B2 (en) 2009-02-06 2016-01-05 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN106546752A (zh) * 2009-02-06 2017-03-29 阿斯图特医药公司 肾损伤和肾衰竭的诊断及预后
CA2770259A1 (en) * 2009-08-07 2011-02-10 Rules-Based Medicine, Inc. Methods and devices for detecting obstructive uropathy and associated disorders
CN102576011B (zh) 2009-08-07 2014-09-17 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断及预后的组合物和方法
CN105004864B (zh) * 2009-09-18 2017-11-03 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断及预后方法和组合物
EP2480882A4 (de) * 2009-09-21 2013-07-10 Astute Medical Inc Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
CA2780464A1 (en) * 2009-10-14 2011-04-21 Rainer Oberbauer Acute kidney injury risk testing
NZ628085A (en) 2009-11-07 2015-12-24 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ702527A (en) 2009-12-20 2016-07-29 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
ES2585184T3 (es) 2010-02-05 2016-10-04 Astute Medical, Inc. Procedimientos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal
AU2011220413B2 (en) 2010-02-26 2015-07-23 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CA2804297A1 (en) 2010-06-23 2011-12-29 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ703055A (en) 2010-06-23 2016-07-29 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
US10935548B2 (en) 2011-12-08 2021-03-02 Astute Medical, Inc. Methods for diagnosis and prognosis of renal injury and renal failure using insulin-like growth factor-binding protein 7 and metalloproteinase inhibitor 2
EP2880442A4 (de) * 2012-08-03 2016-03-16 Astute Medical Inc Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz
EP3361255B1 (de) 2013-01-17 2020-03-11 Astute Medical, Inc. Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz
WO2015084939A1 (en) 2013-12-03 2015-06-11 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CA2944990A1 (en) 2014-04-09 2015-10-15 The Regents Of The University Of California Protein biomarkers for immune assessment and prediction of transplant rejection
US9764078B2 (en) * 2014-06-06 2017-09-19 The University Of Manchester Extracorporeal removal of anti-IQCJ antibodies from blood
EP3281011B1 (de) 2015-04-09 2024-06-05 Astute Medical, Inc. Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz
CA2984589A1 (en) 2015-05-01 2016-11-10 The University Of British Columbia Biomarkers for the detection of acute rejection in heart transplantation
US11243217B2 (en) 2016-06-06 2022-02-08 Astute Medical, Inc. Management of acute kidney injury using insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2
CN113092769A (zh) * 2019-12-23 2021-07-09 首都医科大学附属北京世纪坛医院 尿液补体c4-a及其多肽片段在过敏性疾病中的应用
KR102314642B1 (ko) * 2020-04-17 2021-10-20 재단법인 아산사회복지재단 파브리 병 진단용 바이오 마커 및 이의 용도
EP4397976A1 (de) * 2023-01-09 2024-07-10 x-kidney diagnostics GmbH Biomarker zur präklinischen und/oder frühen erkennung und/oder diagnose von nierenerkrankungen
WO2025183579A1 (en) 2024-02-29 2025-09-04 Ramalhete Lus Manuel Pires Prognostic method for determining a probability of allograft rejection

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Also Published As

Publication number Publication date
CA2600168A1 (en) 2008-03-05
US8021895B2 (en) 2011-09-20
US20120065095A1 (en) 2012-03-15
US8741580B2 (en) 2014-06-03
ES2379430T3 (es) 2012-04-26
EP2333116A2 (de) 2011-06-15
EP1905846A2 (de) 2008-04-02
EP2333116B1 (de) 2015-05-06
EP2333116A3 (de) 2011-10-12
US20080153092A1 (en) 2008-06-26
EP1905846A3 (de) 2008-07-09
GB0617429D0 (en) 2006-10-18
EP1905846B1 (de) 2011-11-16

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