ATE534368T1 - Topische antiakne-zubereitungen mit retinoid (tazaroten oder adapalen), einem antibiotikum (clindamycinphosphat) und/oder keratolytikum (benzoylperoxid in microsponge-form) - Google Patents

Topische antiakne-zubereitungen mit retinoid (tazaroten oder adapalen), einem antibiotikum (clindamycinphosphat) und/oder keratolytikum (benzoylperoxid in microsponge-form)

Info

Publication number
ATE534368T1
ATE534368T1 AT07789585T AT07789585T ATE534368T1 AT E534368 T1 ATE534368 T1 AT E534368T1 AT 07789585 T AT07789585 T AT 07789585T AT 07789585 T AT07789585 T AT 07789585T AT E534368 T1 ATE534368 T1 AT E534368T1
Authority
AT
Austria
Prior art keywords
antibiotic
keratolytic
tazarotene
benzoyl peroxide
retinoid
Prior art date
Application number
AT07789585T
Other languages
English (en)
Inventor
Ayala Fernando Ahumada
Original Assignee
Dermatologicos Darier S A De C V Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dermatologicos Darier S A De C V Lab filed Critical Dermatologicos Darier S A De C V Lab
Application granted granted Critical
Publication of ATE534368T1 publication Critical patent/ATE534368T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/38—Percompounds, e.g. peracids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
AT07789585T 2006-08-08 2007-07-25 Topische antiakne-zubereitungen mit retinoid (tazaroten oder adapalen), einem antibiotikum (clindamycinphosphat) und/oder keratolytikum (benzoylperoxid in microsponge-form) ATE534368T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MXPA06008988A MXPA06008988A (es) 2006-08-08 2006-08-08 Preparaciones topicas antiacne que contienen retinoide (tazaroteno o adapaleno), antibiotico (fosfato de clindamicina) y/o queratolitico (peroxido de bonzoilo en microesponjas).
PCT/IB2007/002195 WO2008017914A2 (en) 2006-08-08 2007-07-25 Topical antiacne preparations containing retinoid (tazarotene or adapalene), antibiotic (clindamycin phosphate) and/or keratolytic (miscrosponged benzoyl peroxide)

Publications (1)

Publication Number Publication Date
ATE534368T1 true ATE534368T1 (de) 2011-12-15

Family

ID=38738792

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07789585T ATE534368T1 (de) 2006-08-08 2007-07-25 Topische antiakne-zubereitungen mit retinoid (tazaroten oder adapalen), einem antibiotikum (clindamycinphosphat) und/oder keratolytikum (benzoylperoxid in microsponge-form)

Country Status (6)

Country Link
US (1) US20090318371A1 (de)
EP (1) EP2049068B1 (de)
AT (1) ATE534368T1 (de)
ES (1) ES2377080T3 (de)
MX (1) MXPA06008988A (de)
WO (1) WO2008017914A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820186B2 (en) 2001-12-21 2010-10-26 Galderma Research & Development Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt
ES2637956T3 (es) 2003-01-24 2017-10-18 Stiefel Research Australia Pty Ltd Espuma farmacéutica
EP2175935B1 (de) 2007-07-06 2018-10-24 Galderma Research & Development Adapalenhaltige topische zusammensetzung zur behandlung von keratinisierungsstörungen
KR101538187B1 (ko) * 2007-11-30 2015-07-22 갈데르마 리써어치 앤드 디벨로프먼트 하나 이상의 나프토산 유도체, 과산화 벤조일 및 하나 이상의 필름-형성제를 함유하는 조성물
US20090175810A1 (en) 2008-01-03 2009-07-09 Gareth Winckle Compositions and methods for treating diseases of the nail
WO2009116086A2 (en) * 2008-03-17 2009-09-24 Glenmark Pharmaceuticals Limited Stable fixed dose topical formulation
EP2282731A1 (de) * 2008-04-24 2011-02-16 Galderma Research & Development Kombinationstherapie für akne vulgaris mit adapalen-0,3%-gel mit clindamycin/benzoyl-peroxid-gel
FR2930727B1 (fr) * 2008-04-30 2012-10-05 Evolution Dermatologique Lab Composition pour le traitement des etats seborrheiques.
CA2723029C (en) 2008-06-05 2016-07-19 Dow Pharmaceutical Sciences, Inc. Topical pharmaceutical formulations containing a low concentration of benzoyl peroxide in suspension in water and a water-miscible organic solvent
PT2400951T (pt) 2009-02-25 2018-11-26 Mayne Pharma Llc Composições de espuma tópica
CN102595892B (zh) * 2009-07-16 2014-09-10 施泰福实验室股份有限公司 他扎罗汀衍生物
CA2769640A1 (en) * 2009-07-30 2011-02-03 Allergan, Inc. Combination of dapsone with adapalene
US20110117182A1 (en) * 2009-07-30 2011-05-19 Allergan, Inc. Combination of dapsone with other anti-acne agents
WO2011101868A2 (en) * 2010-02-18 2011-08-25 Helios Pharmaceuticals Private Limited Stable pharmaceutical preparations containing clindamycin and benzoyl peroxide and method thereof
US8039494B1 (en) 2010-07-08 2011-10-18 Dow Pharmaceutical Sciences, Inc. Compositions and methods for treating diseases of the nail
TW201311295A (zh) * 2011-06-03 2013-03-16 Allergan Inc 對皮脂腺之類視色素化合物之目標遞送
IN2012DE00497A (de) * 2012-02-21 2015-06-05 Ranbaxy Lab Ltd
WO2014042604A1 (en) * 2012-09-11 2014-03-20 Imuneks Farma Mac Sanayi Ve Ticaret A.S. Clindamycin phosphate, salicylic acid and tea tree oil combinations
CN103288893B (zh) * 2013-06-05 2015-08-19 天津大学 克林霉素磷酸酯二甲基亚砜溶剂化合物晶体及制备方法
CN103330678B (zh) * 2013-06-05 2014-12-17 南方医科大学 一种丹皮酚微海绵制剂及其制备方法
CN103288894B (zh) * 2013-06-05 2015-08-19 天津大学 克林霉素磷酸酯甲醇-水溶剂化合物晶体及制备方法
CN103405781B (zh) * 2013-08-26 2014-12-31 江苏知原药业有限公司 复方克林霉素和他扎罗汀脂质复合物的药物组合物
CN104138353B (zh) * 2013-09-05 2016-06-22 江苏中丹制药有限公司 一种他扎罗汀凝胶剂及其制备方法
AU2014329421B2 (en) 2013-10-03 2018-08-02 Dow Pharmaceutical Sciences, Inc. Stabilized efinaconazole compositions
JP6611014B2 (ja) 2013-11-22 2019-11-27 ボシュ ヘルス アイルランド リミテッド 抗感染方法、抗感染組成物、および抗感染装置
WO2016136925A1 (ja) * 2015-02-27 2016-09-01 マルホ株式会社 皮膚用組成物
US9987239B1 (en) 2017-03-14 2018-06-05 Rey Ventures, LLC Pharmaceutical retinoid preparation for topical use
WO2021019092A1 (en) * 2019-08-01 2021-02-04 Bausch Health Ireland Limited Topical compositions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4255418A (en) * 1979-05-14 1981-03-10 Bailey Florence H Anti-acne lotion
US4439614A (en) * 1982-09-22 1984-03-27 Sri International 5,6-Methano-5,6-dihydroretinoids
GB8530796D0 (en) * 1985-12-13 1986-01-22 Beecham Group Plc Pharmaceutical composition
ZA954599B (en) * 1994-06-07 1996-01-26 Allergan Inc Stable gel formulation for topical treatment of skin conditions
US5851538A (en) * 1995-12-29 1998-12-22 Advanced Polymer Systems, Inc. Retinoid formulations in porous microspheres for reduced irritation and enhanced stability
IL123143A (en) * 1998-02-02 2001-08-26 Agis Ind 1983 Ltd Pharmaceutical compositions containing mupirocin
US6730308B1 (en) * 1999-03-08 2004-05-04 Allergan, Inc. Tazarotene and alpha hydroxy acid treatment for psoriasis and/or photodamage
US7820186B2 (en) * 2001-12-21 2010-10-26 Galderma Research & Development Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt
RU2355393C2 (ru) * 2002-12-12 2009-05-20 Галдерма Ресерч Энд Девелопмент, Снс Депигментирующий водно-спиртовой гель
GB0301577D0 (en) * 2003-01-23 2003-02-26 Edko Pazarlama Tanitim Ltd Sti Topical pharmaceutical and/or cosmetic dispense systems
KR20070091613A (ko) * 2004-11-08 2007-09-11 그렌마크 파머수티칼스 엘티디. 항여드름 화합물 및 항생제 화합물을 함유하는 국소적 제약조성물
AR054805A1 (es) * 2005-06-29 2007-07-18 Stiefel Laboratories Composiciones topicas para el tratamiento de la piel

Also Published As

Publication number Publication date
US20090318371A1 (en) 2009-12-24
MXPA06008988A (es) 2008-02-07
WO2008017914A3 (en) 2009-03-26
WO2008017914A2 (en) 2008-02-14
EP2049068B1 (de) 2011-11-23
ES2377080T3 (es) 2012-03-22
EP2049068A2 (de) 2009-04-22

Similar Documents

Publication Publication Date Title
ATE534368T1 (de) Topische antiakne-zubereitungen mit retinoid (tazaroten oder adapalen), einem antibiotikum (clindamycinphosphat) und/oder keratolytikum (benzoylperoxid in microsponge-form)
MX2009008250A (es) Composiciones para aplicacion topica que comprenden un peroxido y retinoide.
AR059601A1 (es) Composiciones estables de vitamina c
MX363379B (es) Formulaciones tópicas estabilizadas que contienen microcápsulas de núcleo-cubierta.
CO6150136A2 (es) Combinacion de adapaleno y peroxido de benzoilo para tratar lesiones de acne
BR112016029338A2 (pt) creme transdérmico
BRPI1106572B8 (pt) Composições que compreendem um retinoide e um inibidor de nfkb e seus métodos de uso
BRPI0410859A (pt) concentrado de carotenóide purificado, composição de carotenóide purificada diluìda, composição adequada para administração oral, substáncia alimentìcia ou bebida adequada para consumo de mamìfero, e, creme, loção ou ungüento tópico
WO2013064412A3 (en) Perfuming compositions and uses thereof
CU20080054A7 (es) Composiciones con suplemento de hierro con tolerancia mejorada
AR058191A1 (es) Composiciones antitranspirantes
WO2022039822A8 (en) Methods and compositions for treating coronavirus infections
ZA200501753B (en) Depigmenting composition for the skin comprising adapalene and at least one depigmenting agent
AR109277A1 (es) Composición y método para el tratamiento de las afecciones de la piel
ATE423831T1 (de) Verbesserte heizölzusammensetzungen
WO2003092621A3 (en) Composition and method for dermatological treatment
WO2009156675A3 (fr) Nouvelles compositions dépigmentantes sous forme d'une composition anhydre sans vaseline et sans élastomère comprenant un dérivé phénolique solubilisé et un rétinoïde
UA96415C2 (ru) Универсальные высококонцентрированные композиции для борьбы с эктопаразитами
MXPA06000752A (es) Desinfectante mucosal no toxico que contiene alcohol isoprpopilico, aceite de ajonjoli, aloe y aceite de limon.
MX340385B (es) Preparaciones topicas antiacne que contienen retinoide (tazaroteno o adapaleno), antibiotico (fosfato de clindamicina) y/o queratolitico (peroxido de benzoilo en microesponjas).
CA2433343A1 (en) Cosmetic compositions containing rosemary extract and dha
WO2008015539A3 (en) Topical preparation containing sirolimus for treating inflammatory skin deseases
WO2022084303A3 (en) Use of polypeptides having dnase activity
WO2018024886A3 (en) Antimicrobial composition
WO2006053249A3 (en) Compositions exhibiting inhibition of cyclooxygenase-2