ATE535601T1 - Züchtung von fremdtransplantationsmaterial in kultur - Google Patents

Züchtung von fremdtransplantationsmaterial in kultur

Info

Publication number: ATE535601T1
Authority: AT; Austria
Prior art keywords: sgs; index; culture; islets; breeding
Prior art date: 2001-09-28

Application number

AT02799523T

Other languages

English (en)

Inventor

Olga Garkavenko

Original Assignee

Diabcell Pty Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-28

Filing date

2002-09-27

Publication date

2011-12-15

2002-09-27 Application filed by Diabcell Pty Ltd filed Critical Diabcell Pty Ltd

2011-12-15 Application granted granted Critical

2011-12-15 Publication of ATE535601T1 publication Critical patent/ATE535601T1/de

Links

238000002054 transplantation Methods 0.000 title 1
DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 abstract 2
238000003501 co-culture Methods 0.000 abstract 2
210000002950 fibroblast Anatomy 0.000 abstract 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
238000004113 cell culture Methods 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1
210000004962 mammalian cell Anatomy 0.000 abstract 1
229960003966 nicotinamide Drugs 0.000 abstract 1
235000005152 nicotinamide Nutrition 0.000 abstract 1
239000011570 nicotinamide Substances 0.000 abstract 1
230000028327 secretion Effects 0.000 abstract 1
210000000717 sertoli cell Anatomy 0.000 abstract 1
210000002966 serum Anatomy 0.000 abstract 1
230000001228 trophic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
- C12N5/0677—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
- C12N5/0683—Cells of the male genital tract, e.g. prostate, epididymis; Non-germinal cells from testis, e.g. Leydig cells, Sertoli cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/34—Sugars
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1323—Adult fibroblasts
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/22—Coculture with; Conditioned medium produced by pancreatic cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/24—Genital tract cells, non-germinal cells from gonads
- C12N2502/246—Cells of the male genital tract, non-germinal testis cells

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Life Sciences & Earth Sciences (AREA)
Biotechnology (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Cell Biology (AREA)
Reproductive Health (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Materials For Medical Uses (AREA)
Mushroom Cultivation (AREA)

AT02799523T 2001-09-28 2002-09-27 Züchtung von fremdtransplantationsmaterial in kultur ATE535601T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
NZ51454601		2001-09-28
PCT/NZ2002/000197 WO2003027270A1 (en)	2001-09-28	2002-09-27	Growing xenotransplant material in culture

Publications (1)

Publication Number	Publication Date
ATE535601T1 true ATE535601T1 (de)	2011-12-15

Family

ID=19928768

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02799523T ATE535601T1 (de)	2001-09-28	2002-09-27	Züchtung von fremdtransplantationsmaterial in kultur

Country Status (4)

Country	Link
US (1)	US20050042746A1 (de)
EP (1)	EP1438395B1 (de)
AT (1)	ATE535601T1 (de)
WO (1)	WO2003027270A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7399751B2 (en) *	1999-11-04	2008-07-15	Sertoli Technologies, Inc.	Production of a biological factor and creation of an immunologically privileged environment using genetically altered Sertoli cells
US20050265977A1 (en) *	1999-04-30	2005-12-01	Elliott Robert B	Xenotransplant for CNS therapy
US20090047325A1 (en) *	1999-04-30	2009-02-19	Neurotrophincell Pty. Limited	Xenotransplant for cns therapy
ES2346400T3 (es) *	1999-04-30	2010-10-15	Neurotrophincell Pty Ltd	Xenotransplante para la terapia del snc.
AU780366B2 (en) *	2000-01-20	2005-03-17	Diatranz Otsuka Limited	Preparation and xenotransplantation of porcine islets
WO2004113516A1 (en) *	2003-06-24	2004-12-29	Diabcell Pty Limited	Porcine islets cultured with porcine sertoli cells for xenotransplantation
CA2531022C (en) *	2003-07-03	2014-09-09	Jannette Dufour	Compositions containing sertoli cells and myoid cells and use thereof in cellular transplants
NZ539491A (en)	2005-04-15	2008-04-30	Living Cell Products Pty Ltd	Swine population and uses thereof
NZ536009A (en) *	2005-04-18	2007-01-26	Neurotrophincell Pty Ltd	Choroid plexus preparation and uses thereof
NZ540597A (en) *	2005-06-08	2007-02-23	Neurotrophincell Pty Ltd	A method for preventing the onset of type I diabetes comprising administering an implantable composition comprising living choroid plexus cells
US20090090214A1 (en) *	2007-10-04	2009-04-09	Chung Yuan Christian University	Method for forming nano-scale metal particles
US9420770B2 (en)	2009-12-01	2016-08-23	Indiana University Research & Technology Corporation	Methods of modulating thrombocytopenia and modified transgenic pigs

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5266480A (en) *	1986-04-18	1993-11-30	Advanced Tissue Sciences, Inc.	Three-dimensional skin culture system
US4850993A (en) *	1986-12-22	1989-07-25	Miles Laboratories, Inc.	Blood bag system incorporating quinolone carboxylic, acid derivatives
US5283187A (en) *	1987-11-17	1994-02-01	Brown University Research Foundation	Cell culture-containing tubular capsule produced by co-extrusion
US5871472A (en) *	1987-11-17	1999-02-16	Brown University Research Foundation	Planting devices for the focal release of neuroinhibitory compounds
US5650148A (en) *	1988-12-15	1997-07-22	The Regents Of The University Of California	Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system
ATE156344T1 (de) *	1991-04-25	1997-08-15	Univ Brown Res Found	Implantierbare, biokompatible immunisolator- trägersubstanz zum abgeben ausgesuchter, therapeutischer produkte
PT696205E (pt) *	1993-04-13	2002-07-31	Us Gov Health & Human Serv	Utilizacao de linhas celulares fetais nauro-derivadas para terapia de transplantacao
US6090400A (en) *	1994-02-07	2000-07-18	The Trustees Of The Childhood Diabetes Transplant Research Trust	Pharmaceutical preparation and method for treatment of diabetes
DK0755258T3 (da) *	1994-04-13	2002-05-13	Res Corp Technologies Inc	Fremgangsmåde til behandling af sygdom ved at anvende Sertoli-celler og allo-transplantater eller xeno-transplantater
US5958404A (en) *	1994-04-13	1999-09-28	Research Corporation Technologies, Inc.	Treatment methods for disease using co-localized cells and Sertoli cells obtained from a cell line
US5849285A (en) *	1994-04-13	1998-12-15	Research Corporation Technologies, Inc.	Autoimmune disease treatment with sertoli cells and in vitro co-culture of mammal cells with sertoli cells
US5550050A (en) *	1994-04-15	1996-08-27	Cytotherapeutics, Inc.	Method for implanting encapsulated cells in a host
US6001647A (en) *	1994-04-28	1999-12-14	Ixion Biotechnology, Inc.	In vitro growth of functional islets of Langerhans and in vivo uses thereof
US5587309A (en) *	1994-04-29	1996-12-24	The United States Of America As Represented By The Department Of Health And Human Services	Method of stimulating proliferation and differentiation of human fetal pancreatic cells ex vivo
US5898066A (en) *	1994-08-26	1999-04-27	Children's Medical Center Corporation	Trophic factors for central nervous system regeneration
US5853385A (en) *	1994-08-26	1998-12-29	Cytotherapeutics, Inc.	Encapsulated PC12 cell transplants for treatment of Parkinson's disease
AU7443996A (en) *	1995-10-30	1997-05-22	Vivorx, Inc.	Method for ex vivo proliferation and differentiation of adult pancreatic islet cells, media useful therefor and uses thereof
CA2179341A1 (en) *	1996-04-12	1997-10-13	Gregory S. Korbutt	Methods for isolating, enriching and increasing the maturation of cells
US6001643A (en) *	1997-08-04	1999-12-14	C-Med Inc.	Controlled hydrodynamic cell culture environment for three dimensional tissue growth
US5968829A (en) *	1997-09-05	1999-10-19	Cytotherapeutics, Inc.	Human CNS neural stem cells
US6432710B1 (en) *	1998-05-22	2002-08-13	Isolagen Technologies, Inc.	Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
KR100502285B1 (ko) *	1998-12-15	2005-07-20	유니버시다드 나시오날 오토노마 드 멕시코	생물학적 물질의 이식물을 발육시키는 방법 및 장치
US6365385B1 (en) *	1999-03-22	2002-04-02	Duke University	Methods of culturing and encapsulating pancreatic islet cells
EP1333846B1 (de) *	2000-10-17	2012-04-18	Diabcell Pty Limited	Zubereitung und xenotransplantation von langerhans-inseln von schweinen
AU2002339299A1 (en) *	2001-05-18	2002-12-03	Cornell Research Foundation, Inc.	In vitro production of haploid germ cells

2002
- 2002-09-27 AT AT02799523T patent/ATE535601T1/de active
- 2002-09-27 EP EP02799523A patent/EP1438395B1/de not_active Expired - Lifetime
- 2002-09-27 WO PCT/NZ2002/000197 patent/WO2003027270A1/en not_active Ceased
- 2002-09-27 US US10/490,717 patent/US20050042746A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1438395A4 (de)	2006-04-12
EP1438395A1 (de)	2004-07-21
HK1067151A1 (en)	2005-04-01
WO2003027270A1 (en)	2003-04-03
EP1438395B1 (de)	2011-11-30
US20050042746A1 (en)	2005-02-24

Publication	Publication Date	Title
ATE535601T1 (de)	2011-12-15	Züchtung von fremdtransplantationsmaterial in kultur
DE69533223D1 (de)	2004-08-05	Zusammensetzungen und verfahren zur stimulierung der proliferation und der differenzierung von menschlichen fetalen und erwachsenen pankreatischen zellen ex vivo
Takaku et al.	2014	In vivo cell tracking by bioluminescence imaging after transplantation of bioengineered cell sheets to the knee joint
CN105112362B (zh)	2018-08-03	一种胎盘间充质干细胞的无血清培养基及其制备方法
KR20040045856A (ko)	2004-06-02	상처 치료용 생물학적 활성 물질로서 사용될 수 있는각질세포
EP2180043A1 (de)	2010-04-28	Verfahren zur Unterscheidung von menschlichen erwachsenen Stammzellen in insulinabgebende Zellen
CN101757690A (zh)	2010-06-30	一种制备组织工程角膜的方法
Saxena	2005	Tissue engineering: Present concepts and strategies
CN109112101A (zh)	2019-01-01	一种成纤维细胞培养基及其应用
Higa et al.	2008	Recent advances in cultivated epithelial transplantation
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Mohammad-Pour et al.	2025	Comparing the effects of two cryoprotectant protocols, dimethyl-sulfoxide (DMSO) and glycerol, on the recovery rate of cultured keratinocytes on amniotic membrane
CA2320423A1 (en)	1999-09-02	Derivation of cells and tissues from embryonic pre-stem cells for transplantation therapies
CN105963795A (zh)	2016-09-28	一种基于胶原制备组织工程表皮的方法
Viravaidya-Pasuwat et al.	2013	Construction of a chondrocyte cell sheet using temperature-responsive poly (N-isopropylacrylamide)-co-acrylamide
CN105087466A (zh)	2015-11-25	诱导脐带间充质干细胞向角膜上皮细胞分化的培养基和方法
US20100015198A1 (en)	2010-01-21	Transplants encapsulated with self-elastic cartilage and method of preparing the same