ATE535602T1 - Modifiziertes insulin mit reduzierter immunogenität - Google Patents

Modifiziertes insulin mit reduzierter immunogenität

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Publication number
ATE535602T1
ATE535602T1 AT02736480T AT02736480T ATE535602T1 AT E535602 T1 ATE535602 T1 AT E535602T1 AT 02736480 T AT02736480 T AT 02736480T AT 02736480 T AT02736480 T AT 02736480T AT E535602 T1 ATE535602 T1 AT E535602T1
Authority
AT
Austria
Prior art keywords
reduced immunogenicity
modified insulin
insulin
modified
immunogenicity
Prior art date
Application number
AT02736480T
Other languages
English (en)
Inventor
Pradip Mukerji
Yung-Sheng Huang
Tapas Das
Jennifer Thurmond
Suzette Pereira
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Priority claimed from PCT/US2002/001924 external-priority patent/WO2002081668A2/en
Application granted granted Critical
Publication of ATE535602T1 publication Critical patent/ATE535602T1/de

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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
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    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

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  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Nutrition Science (AREA)
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AT02736480T 2001-01-25 2002-01-24 Modifiziertes insulin mit reduzierter immunogenität ATE535602T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/769,863 US6635451B2 (en) 2001-01-25 2001-01-25 Desaturase genes and uses thereof
US10/054,534 US7067285B2 (en) 2001-01-25 2002-01-22 Desaturase genes and uses thereof
PCT/US2002/001924 WO2002081668A2 (en) 2001-01-25 2002-01-24 Desaturase genes and uses thereof

Publications (1)

Publication Number Publication Date
ATE535602T1 true ATE535602T1 (de) 2011-12-15

Family

ID=27735000

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02736480T ATE535602T1 (de) 2001-01-25 2002-01-24 Modifiziertes insulin mit reduzierter immunogenität

Country Status (8)

Country Link
US (6) US6635451B2 (de)
EP (2) EP2325300B1 (de)
JP (3) JP4347397B2 (de)
AR (1) AR035534A1 (de)
AT (1) ATE535602T1 (de)
CA (2) CA2698579C (de)
ES (1) ES2377198T3 (de)
PT (1) PT1392823E (de)

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US6635451B2 (en) * 2001-01-25 2003-10-21 Abbott Laboratories Desaturase genes and uses thereof
US20050089879A1 (en) * 2001-07-31 2005-04-28 Ivo Feussner Method for producing arachidonic acid in transgenic organisms
DE10219203A1 (de) * 2002-04-29 2003-11-13 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen
EP1619960A4 (de) * 2003-03-07 2009-03-18 Advanced Bionutrition Corp Futtermittelformulierung für land- und wasserbewohner
PL1656449T3 (pl) * 2003-08-21 2009-08-31 Monsanto Technology Llc Desaturazy kwasów tłuszczowych z Primula
CA2562548C (en) 2004-04-16 2019-08-20 Monsanto Technology Llc Expression of fatty acid desaturases in corn
ES2529572T3 (es) 2004-04-22 2015-02-23 Commonwealth Scientific And Industrial Research Organisation Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
AU2011232757B2 (en) * 2004-04-22 2013-10-03 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
EP2363492A3 (de) 2004-04-22 2012-03-14 Commonwealth Scientific and Industrial Research Organisation Synthese von langkettigen polyungesättigten Fettsäuren durch rekombinante Zellen
US7364883B2 (en) * 2004-05-07 2008-04-29 Yeastern Biotech Co., Ltd. Process for producing poly-unsaturated fatty acids by oleaginous yeasts
BRPI0511236A (pt) * 2004-06-04 2007-11-27 Fluxome Sciences As método para a produção de ácidos graxos poliinsaturados com quatro ou mais ligações duplas, saccharomyces cerevisiae geneticamente modificado que tem capacidade de produzir ácidos graxos poliinsaturados com quatro ou mais ligações duplas quando desenvolvido em um substrato que não de ácido graxo, composição, uso da composição e uso de um saccharomyces cervisiae geneticamente modificado
US8685679B2 (en) * 2004-11-04 2014-04-01 E I Du Pont De Nemours And Company Acyltransferase regulation to increase the percent of polyunsaturated fatty acids in total lipids and oils of oleaginous organisms
US7550286B2 (en) * 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
JP2008532553A (ja) * 2005-03-16 2008-08-21 メタボリックス, インコーポレイテッド 生合成経路の化学的に誘導可能な発現
EP1885862B1 (de) 2005-05-23 2015-07-29 Arcadia Biosciences Inc. Florsafran mit erhöhter gamma-linolensäure
EP3467096B1 (de) 2005-06-07 2022-01-12 DSM Nutritional Products AG Eukaryotische mikroorganismen zur herstellung von lipiden und antioxidantien
EP1991047B1 (de) 2006-03-01 2012-09-26 Pioneer Hi-Bred International Inc. Zusammensetzung in zusammenhang mit dem quantitative trait locus 6 (qtl6) in mais und anwendungsverfahren dafür
US7465793B2 (en) 2006-04-20 2008-12-16 E.I. Du Pont De Nemours And Company Synthetic Δ17 desaturase derived from Phytophthora ramourum and its use in making polyunsaturated fatty acids
ES2572833T3 (es) * 2006-08-01 2016-06-02 Dsm Nutritional Products Ag Proceso de producción de aceite microbiano que contiene ácidos grasos poliinsaturados
US8816106B2 (en) 2006-08-29 2014-08-26 Commonwealth Scientific And Industrial Research Organisation Synthesis of fatty acids
US7556949B2 (en) * 2006-10-30 2009-07-07 E.I. Du Pont De Nemours And Company Δ17 desaturase and its use in making polyunsaturated fatty acids
US7943365B2 (en) 2007-05-03 2011-05-17 E.I. Du Pont De Nemours And Company Δ-5 desaturases and their use in making polyunsaturated fatty acids
US8765422B2 (en) * 2007-07-13 2014-07-01 Dsm Nutritional Products Ag D4 desaturases and D5 elongases
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