ATE536181T1 - Metabolite von wortmannin-analogen und verwendungsverfahren dafür - Google Patents

Metabolite von wortmannin-analogen und verwendungsverfahren dafür

Info

Publication number
ATE536181T1
ATE536181T1 AT06851064T AT06851064T ATE536181T1 AT E536181 T1 ATE536181 T1 AT E536181T1 AT 06851064 T AT06851064 T AT 06851064T AT 06851064 T AT06851064 T AT 06851064T AT E536181 T1 ATE536181 T1 AT E536181T1
Authority
AT
Austria
Prior art keywords
metabolites
methods
wortmannin
analogues
wortmannin analogues
Prior art date
Application number
AT06851064T
Other languages
English (en)
Inventor
Garth Powis
Original Assignee
Univ Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Arizona filed Critical Univ Arizona
Application granted granted Critical
Publication of ATE536181T1 publication Critical patent/ATE536181T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
AT06851064T 2005-12-30 2006-12-29 Metabolite von wortmannin-analogen und verwendungsverfahren dafür ATE536181T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75547705P 2005-12-30 2005-12-30
PCT/US2006/062716 WO2007120364A2 (en) 2005-12-30 2006-12-29 Metabolites of wortmannin analogs and methods of using the same

Publications (1)

Publication Number Publication Date
ATE536181T1 true ATE536181T1 (de) 2011-12-15

Family

ID=38610016

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06851064T ATE536181T1 (de) 2005-12-30 2006-12-29 Metabolite von wortmannin-analogen und verwendungsverfahren dafür

Country Status (8)

Country Link
US (3) US7723375B2 (de)
EP (1) EP1965790B1 (de)
AT (1) ATE536181T1 (de)
AU (1) AU2006342055B2 (de)
CA (1) CA2636040C (de)
ES (1) ES2378780T3 (de)
PL (1) PL1965790T3 (de)
WO (1) WO2007120364A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012523429A (ja) * 2009-04-09 2012-10-04 オンコシレオン，インコーポレイテッド 線維症を処置するための方法およびｐｉ−３キナーゼインヒビターの組成物
WO2012118978A1 (en) * 2011-03-03 2012-09-07 The Regents Of The University Of Colorado, A Body Corporate Methods for treating oncovirus positive cancers
US11197854B1 (en) 2018-11-14 2021-12-14 National Technology & Engineering Solutions Of Sandia, Llc Inhibitors for targeting flaviviruses
CN115266967B (zh) * 2022-07-11 2025-02-18 瑞阳制药股份有限公司 青霉素钠有关物质的超高效液相色谱法测定方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001064A (en) 1988-06-20 1991-03-19 Washington University Phosphatidylinositol 4-kinase
AU4191989A (en) 1988-08-24 1990-03-23 Marvin J. Slepian Biodegradable polymeric endoluminal sealing
US5504103A (en) * 1993-08-25 1996-04-02 Eli Lilly And Company Inhibition of phosphatidylinositol 3-kinase with 17 β-hydroxywortmannin and analogs thereof
US5480906A (en) * 1994-07-01 1996-01-02 Eli Lilly And Company Stereochemical Wortmannin derivatives
DK0769014T3 (da) * 1994-07-01 1999-06-28 Monsanto Co Fremgangsmåde til fremstilling af N-phosphonomethylaminocarboxylsyrer
US5602278A (en) 1994-10-20 1997-02-11 Kirkpatrick; Lynn N-oxides and derivatives of chlorambucil for treating hypoxic tumor cells
GB2302021A (en) 1996-10-16 1997-01-08 Lilly Co Eli Inhibiting bone loss or resorption
US7081475B2 (en) 2001-09-14 2006-07-25 Prolx Pharmaceuticals Corp. Wortmannin analogs and methods of using same
ATE334671T1 (de) * 2001-09-14 2006-08-15 Univ Arizona Wortmanninanaloge und verfahren zu deren verwendung
US6703414B2 (en) 2001-09-14 2004-03-09 Arizona Board Of Regents On Behalf Of The University Of Arizona Device and method for treating restenosis
CA2578336C (en) 2004-07-09 2013-09-24 Prolx Pharmaceuticals Corp. Wortmannin analogs and methods of using same in combination with chemotherapeutic agents
CN101039952A (zh) * 2004-10-13 2007-09-19 惠氏公司 作为pi3k抑制剂的17－羟基渥曼青霉素类似物

Also Published As

Publication number Publication date
EP1965790A4 (de) 2009-06-24
WO2007120364A3 (en) 2008-07-24
EP1965790A2 (de) 2008-09-10
WO2007120364A2 (en) 2007-10-25
US20070191466A1 (en) 2007-08-16
US20100249205A1 (en) 2010-09-30
US20100063129A9 (en) 2010-03-11
US8586626B2 (en) 2013-11-19
US20110263672A1 (en) 2011-10-27
AU2006342055B2 (en) 2012-05-24
ES2378780T3 (es) 2012-04-17
PL1965790T3 (pl) 2012-05-31
EP1965790B1 (de) 2011-12-07
CA2636040A1 (en) 2007-10-25
US7723375B2 (en) 2010-05-25
CA2636040C (en) 2013-12-17
AU2006342055A1 (en) 2007-10-25

Similar Documents

Publication Publication Date Title
NL301145I2 (nl) Tirbanibulin
ATE517896T1 (de) P38-kinase-inhibitoren
BRPI0412918A (pt) inibidores de quinases p38
EP3677584A4 (de) Verbindung mit bruton-tyrosinkinase (btk)-hemmung und abbau
ATE408412T1 (de) Verwendung von cannabidiol zur hemmung von gehirntumorzellmigration
GB0402143D0 (en) Novel compounds
MA33974B1 (fr) Combinaisons d'un inhibiteur de pi3k et d'un inhibiteur de mek
EA200501563A1 (ru) Пролекарства ингибиторов киназы pi-3
ECSP088440A (es) Imidazopirazinas como inhibidores de proteinquinasa
MX2009007944A (es) Compuestos y composiciones de purina como inhibidores de quinasa para el tratamiento de enfermedades relacionadas con plasmodium.
MY145070A (en) Imidazolothiazole compounds for the treatment of disease
PL2878297T3 (pl) Leki do leczenia lub zapobiegania chorobom zwłóknieniowym
NO20065148L (no) Monocykliske heterocykler som kinase inhibitorer
TW200637547A (en) Compounds and compositions as protein kinase inhibitors
ATE539752T1 (de) Verwendung von pi3k- und mek-modulatoren bei der krebsbehandlung
NO20072179L (no) Kombinasjon av en SRC kinase inhibitor og en. BCR-ABL inhibitor for behandling av proleferative sykdommer
CY1108399T1 (el) Τετραϋδροπυριδοθειοφαινια
CL2007002382A1 (es) Uso de compuestos derivados de 2,5-dihidroxibenceno para el tratamiento del cancer a la piel.
GB0121490D0 (en) Ciompounds
BRPI0515319A (pt) análogos de quinolona
BRPI0515518A (pt) análogos de loxapina e métodos de usos dos mesmos
NO20081292L (no) Pentasykliske kinaseinhibitorer
ATE435858T1 (de) Prodrugs von als erk-proteinkinase-inhibitoren wirkenden pyrrolylpyrimidinen
EP1965790A4 (de) Metabolite von wortmannin-analogen und verwendungsverfahren dafür
ATE397000T1 (de) Tetrahydropyridothiophenen zur verwendung in der behandlung von krebs