ATE536404T1 - Isolierung von zellen - Google Patents
Isolierung von zellenInfo
- Publication number
- ATE536404T1 ATE536404T1 AT07808564T AT07808564T ATE536404T1 AT E536404 T1 ATE536404 T1 AT E536404T1 AT 07808564 T AT07808564 T AT 07808564T AT 07808564 T AT07808564 T AT 07808564T AT E536404 T1 ATE536404 T1 AT E536404T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- isolation
- cartilage
- chondrocytes
- relates
- Prior art date
Links
- 238000002955 isolation Methods 0.000 title 1
- 210000000845 cartilage Anatomy 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 abstract 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000001612 chondrocyte Anatomy 0.000 abstract 1
- 210000002744 extracellular matrix Anatomy 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3852—Cartilage, e.g. meniscus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3633—Extracellular matrix [ECM]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Botany (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- General Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Prostheses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06076645A EP1894581A1 (de) | 2006-08-31 | 2006-08-31 | Regeneration von Knorpelgewebe unter Verwendung eines Chondrozyten enthaltenden Matrixgels |
| PCT/NL2007/050431 WO2008026929A1 (en) | 2006-08-31 | 2007-08-31 | Isolation of cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE536404T1 true ATE536404T1 (de) | 2011-12-15 |
Family
ID=37771022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07808564T ATE536404T1 (de) | 2006-08-31 | 2007-08-31 | Isolierung von zellen |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8697442B2 (de) |
| EP (4) | EP1894581A1 (de) |
| AT (1) | ATE536404T1 (de) |
| AU (1) | AU2007289432B2 (de) |
| CA (2) | CA2662292C (de) |
| ES (3) | ES2685069T3 (de) |
| PL (3) | PL3388091T3 (de) |
| SI (2) | SI3388091T1 (de) |
| WO (2) | WO2008026929A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1894581A1 (de) * | 2006-08-31 | 2008-03-05 | CellCoTec B.V. | Regeneration von Knorpelgewebe unter Verwendung eines Chondrozyten enthaltenden Matrixgels |
| GB0617777D0 (en) * | 2006-09-09 | 2006-10-18 | Univ Cardiff | Cartilage repair |
| EP2034010A1 (de) | 2007-08-30 | 2009-03-11 | Omrix Biopharmaceuticals Ltd. | Zusammensetzungen zur Reparatur und/oder Behandlung von verletztem Rückenmarksgewebe |
| US8198278B2 (en) | 2007-12-19 | 2012-06-12 | Sunovion Pharmaceuticals Inc. | Besylate salts of 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine |
| DE102009018640A1 (de) * | 2009-04-17 | 2010-10-21 | Tetec Tissue Engineering Technologies Ag | Implantat und therapeutische Zusammensetzung zur Behandlung von Schäden und/oder Erkrankungen im Bereich des menschlichen und/oder tierischen Stütz- und Bewegungsapparates |
| WO2012021814A2 (en) | 2010-08-13 | 2012-02-16 | Wake Forest University Health Sciences | Methods for making a tissue engineered muscle repair (temr) construct in vitro for implantation in vivo |
| JP6238445B2 (ja) * | 2011-10-27 | 2017-11-29 | 国立大学法人 東京医科歯科大学 | 大腸上皮幹細胞の単離・培養技術と、これを用いた大腸上皮移植技術 |
| US10016528B2 (en) * | 2013-09-09 | 2018-07-10 | Eran Rosines | Biologic prosthesis and methods of production and use |
| DE102014213571A1 (de) * | 2014-07-11 | 2016-01-14 | Tetec Tissue Engineering Technologies Ag | Identität und Reinheit von Gewebebiopsaten |
| EP3528750B1 (de) | 2016-10-20 | 2020-07-08 | Technische Universiteit Eindhoven | Biomimetisches funktionelles und regeneratives knorpelimplantat |
| KR102588627B1 (ko) * | 2017-03-08 | 2023-10-16 | 김성진 | Mast4 유전자를 이용한 세포외 기질 생산용 조성물 및 그 제조방법 |
| CN111892719B (zh) * | 2020-06-12 | 2022-12-16 | 华南理工大学 | 一种用于软骨细胞三维培养的透明质酸超分子水凝胶及其制备与应用 |
| CN114848914B (zh) * | 2021-01-20 | 2025-03-28 | 上海软馨生物科技有限公司 | 一种软骨组织工程复合物及其用途 |
| CN115040636B (zh) * | 2021-02-25 | 2025-06-13 | 杭州彗搏科技有限公司 | 多肽在促进软骨再生或修复中的用途 |
| CN115944781B (zh) * | 2021-10-09 | 2025-03-28 | 上海软馨生物科技有限公司 | 一种基于3d打印的软骨组织工程复合物及其用途 |
| NL2031814B1 (en) | 2022-05-10 | 2023-11-17 | Cartiregen B V | Methods for isolating cells from a tissue sample. |
| CN115261307B (zh) * | 2022-07-28 | 2023-08-08 | 中山大学 | 一种骨细胞裂解液基/囊泡基水凝胶及其制备方法和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4846835A (en) * | 1987-06-15 | 1989-07-11 | Grande Daniel A | Technique for healing lesions in cartilage |
| US5830741A (en) * | 1996-12-06 | 1998-11-03 | Boehringer Mannheim Corporation | Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease |
| EP1018987B1 (de) * | 1997-04-04 | 2014-10-29 | Barnes-Jewish Hospital | Neo-knorpel und seine gebrauchsverfahren |
| CA2254350A1 (en) * | 1998-11-17 | 2000-05-17 | Hsc Research And Development Limited Partnership | Method for bioengineering cartilage |
| DE10026789B4 (de) * | 2000-05-31 | 2004-09-02 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Knorpelersatz und Verfahren zu dessen Herstellung |
| US6991652B2 (en) * | 2000-06-13 | 2006-01-31 | Burg Karen J L | Tissue engineering composite |
| IL154121A0 (en) * | 2000-07-24 | 2003-07-31 | Shawn Alan Stewart | A method and system for purifying or cleansing a gas stream or gaseous body |
| WO2002067856A2 (en) * | 2001-02-23 | 2002-09-06 | University Of Massachusetts | Injection molding of living tissues |
| FR2822842B1 (fr) | 2001-03-30 | 2004-11-19 | Genevrier Lab | Procede de preparation d'un neo-tissu cartilagineux |
| FR2823217A1 (fr) * | 2001-04-09 | 2002-10-11 | Oreal | Procede d'obtention d'une suspension de cellules individualisees issues d'un equivalent de peau humaine reconstruite et applications |
| US7468192B2 (en) * | 2002-03-22 | 2008-12-23 | Histogenics Corporation | Method for repair of cartilage lesions |
| EP1894581A1 (de) * | 2006-08-31 | 2008-03-05 | CellCoTec B.V. | Regeneration von Knorpelgewebe unter Verwendung eines Chondrozyten enthaltenden Matrixgels |
-
2006
- 2006-08-31 EP EP06076645A patent/EP1894581A1/de not_active Withdrawn
-
2007
- 2007-08-31 ES ES07808563.6T patent/ES2685069T3/es active Active
- 2007-08-31 SI SI200732160T patent/SI3388091T1/sl unknown
- 2007-08-31 PL PL18174505T patent/PL3388091T3/pl unknown
- 2007-08-31 EP EP07808563.6A patent/EP2061527B8/de active Active
- 2007-08-31 WO PCT/NL2007/050431 patent/WO2008026929A1/en not_active Ceased
- 2007-08-31 US US12/439,145 patent/US8697442B2/en active Active
- 2007-08-31 ES ES07808564T patent/ES2377951T3/es active Active
- 2007-08-31 WO PCT/NL2007/050430 patent/WO2008026928A2/en not_active Ceased
- 2007-08-31 EP EP07808564A patent/EP2064317B1/de active Active
- 2007-08-31 SI SI200732052T patent/SI2061527T1/sl unknown
- 2007-08-31 AT AT07808564T patent/ATE536404T1/de active
- 2007-08-31 PL PL07808563T patent/PL2061527T3/pl unknown
- 2007-08-31 US US12/439,090 patent/US9072819B2/en active Active
- 2007-08-31 PL PL07808564T patent/PL2064317T3/pl unknown
- 2007-08-31 CA CA2662292A patent/CA2662292C/en active Active
- 2007-08-31 ES ES18174505T patent/ES2813619T3/es active Active
- 2007-08-31 CA CA2662111A patent/CA2662111C/en active Active
- 2007-08-31 EP EP18174505.0A patent/EP3388091B1/de active Active
- 2007-08-31 AU AU2007289432A patent/AU2007289432B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3388091B1 (de) | 2020-05-27 |
| PL2064317T3 (pl) | 2012-05-31 |
| WO2008026928A3 (en) | 2008-04-24 |
| CA2662111C (en) | 2015-10-13 |
| ES2813619T3 (es) | 2021-03-24 |
| CA2662292C (en) | 2015-11-24 |
| EP2061527B1 (de) | 2018-05-30 |
| PL2061527T3 (pl) | 2018-12-31 |
| US9072819B2 (en) | 2015-07-07 |
| AU2007289432A1 (en) | 2008-03-06 |
| AU2007289433A1 (en) | 2008-03-06 |
| EP3388091A1 (de) | 2018-10-17 |
| ES2685069T3 (es) | 2018-10-05 |
| US20100144036A1 (en) | 2010-06-10 |
| ES2377951T3 (es) | 2012-04-03 |
| SI2061527T1 (sl) | 2018-10-30 |
| EP2064317B1 (de) | 2011-12-07 |
| AU2007289432B2 (en) | 2012-12-13 |
| EP2064317A1 (de) | 2009-06-03 |
| EP2061527B8 (de) | 2018-07-25 |
| US8697442B2 (en) | 2014-04-15 |
| SI3388091T1 (sl) | 2020-11-30 |
| PL3388091T3 (pl) | 2020-11-16 |
| EP1894581A1 (de) | 2008-03-05 |
| EP2061527A2 (de) | 2009-05-27 |
| US20100047316A1 (en) | 2010-02-25 |
| CA2662111A1 (en) | 2008-03-06 |
| CA2662292A1 (en) | 2008-03-06 |
| WO2008026929A1 (en) | 2008-03-06 |
| WO2008026928A2 (en) | 2008-03-06 |
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