ATE536425T1 - Mit metabolischem alter verbundene biomarker und verfahren zur verwendung davon - Google Patents

Mit metabolischem alter verbundene biomarker und verfahren zur verwendung davon

Info

Publication number
ATE536425T1
ATE536425T1 AT07868439T AT07868439T ATE536425T1 AT E536425 T1 ATE536425 T1 AT E536425T1 AT 07868439 T AT07868439 T AT 07868439T AT 07868439 T AT07868439 T AT 07868439T AT E536425 T1 ATE536425 T1 AT E536425T1
Authority
AT
Austria
Prior art keywords
methods
metabolic age
biomarkers
biomarkers associated
age
Prior art date
Application number
AT07868439T
Other languages
English (en)
Inventor
John Ryals
Mike Milburn
Matthew W Mitchell
Kay A Lawton
Original Assignee
Metabolon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolon Inc filed Critical Metabolon Inc
Application granted granted Critical
Publication of ATE536425T1 publication Critical patent/ATE536425T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7042—Aging, e.g. cellular aging

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Toxicology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AT07868439T 2006-10-13 2007-10-12 Mit metabolischem alter verbundene biomarker und verfahren zur verwendung davon ATE536425T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85146806P 2006-10-13 2006-10-13
PCT/US2007/081268 WO2008063783A2 (en) 2006-10-13 2007-10-12 Biomarkers related to metabolic age and methods using the same

Publications (1)

Publication Number Publication Date
ATE536425T1 true ATE536425T1 (de) 2011-12-15

Family

ID=39430420

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07868439T ATE536425T1 (de) 2006-10-13 2007-10-12 Mit metabolischem alter verbundene biomarker und verfahren zur verwendung davon

Country Status (6)

Country Link
US (3) US7781160B2 (de)
EP (3) EP2428587A3 (de)
JP (1) JP5363984B2 (de)
AT (1) ATE536425T1 (de)
CA (1) CA2666339A1 (de)
WO (1) WO2008063783A2 (de)

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EP2642296A1 (de) * 2012-03-22 2013-09-25 Nestec S.A. p-Cresolsulfat als Biomarker für gesundes Altern
EP2642294A1 (de) * 2012-03-22 2013-09-25 Nestec S.A. Phenylacetylglutamin als Biomarker für gesundes Altern
EP2642293A1 (de) 2012-03-22 2013-09-25 Nestec S.A. 9-oxo-octadecadiensäure (9-oxo-HODE) als Biomarker für gesundes Altern
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JP7437767B2 (ja) * 2018-04-24 2024-02-26 学校法人沖縄科学技術大学院大学学園 ヒトの老化バイオマーカーとしての、唾液及び尿の代謝物の使用
CN108663448B (zh) * 2018-05-14 2021-07-13 中国医学科学院医药生物技术研究所 一种复方氨基酸注射液中有关物质的检测方法
WO2020252206A1 (en) * 2019-06-12 2020-12-17 Huntington Medical Research Institutes Methods for evaluation and treatment of alzheimer's disease and applications thereof
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CN113125589B (zh) * 2021-03-17 2022-01-04 广东省农业科学院农业质量标准与监测技术研究所 一种代谢组学分析技术鉴定鸭屎香单丛茶的应用
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Also Published As

Publication number Publication date
US20080124752A1 (en) 2008-05-29
EP2428587A3 (de) 2012-07-18
WO2008063783A2 (en) 2008-05-29
US20100279337A1 (en) 2010-11-04
US20160116461A1 (en) 2016-04-28
JP5363984B2 (ja) 2013-12-11
EP2089539A2 (de) 2009-08-19
JP2010507075A (ja) 2010-03-04
CA2666339A1 (en) 2008-05-29
EP2428587A2 (de) 2012-03-14
WO2008063783A3 (en) 2008-12-24
EP2089539A4 (de) 2010-03-17
EP2813580A1 (de) 2014-12-17
US7781160B2 (en) 2010-08-24
EP2089539B1 (de) 2011-12-07

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