ATE536869T1 - Auf glucan-film basierte wirkstoffverabreichungssysteme - Google Patents

Auf glucan-film basierte wirkstoffverabreichungssysteme

Info

Publication number
ATE536869T1
ATE536869T1 AT02769061T AT02769061T ATE536869T1 AT E536869 T1 ATE536869 T1 AT E536869T1 AT 02769061 T AT02769061 T AT 02769061T AT 02769061 T AT02769061 T AT 02769061T AT E536869 T1 ATE536869 T1 AT E536869T1
Authority
AT
Austria
Prior art keywords
drug delivery
delivery systems
film based
based drug
glucan
Prior art date
Application number
AT02769061T
Other languages
English (en)
Inventor
Robert K Yang
Richard C Fuisz
Original Assignee
Monosolrx Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/074,272 external-priority patent/US7425292B2/en
Application filed by Monosolrx Llc filed Critical Monosolrx Llc
Application granted granted Critical
Publication of ATE536869T1 publication Critical patent/ATE536869T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B13/00—Machines and apparatus for drying fabrics, fibres, yarns, or other materials in long lengths, with progressive movement
    • F26B13/10—Arrangements for feeding, heating or supporting materials; Controlling movement, tension or position of materials
    • F26B13/101—Supporting materials without tension, e.g. on or between foraminous belts
    • F26B13/104—Supporting materials without tension, e.g. on or between foraminous belts supported by fluid jets only; Fluid blowing arrangements for flotation dryers, e.g. coanda nozzles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Textile Engineering (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
AT02769061T 2001-10-12 2002-10-11 Auf glucan-film basierte wirkstoffverabreichungssysteme ATE536869T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US32886801P 2001-10-12 2001-10-12
US10/074,272 US7425292B2 (en) 2001-10-12 2002-02-14 Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US37194002P 2002-04-11 2002-04-11
US38693702P 2002-06-07 2002-06-07
PCT/US2002/032542 WO2003030881A1 (en) 2001-10-12 2002-10-11 Glucan based film delivery systems

Publications (1)

Publication Number Publication Date
ATE536869T1 true ATE536869T1 (de) 2011-12-15

Family

ID=27491110

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02769061T ATE536869T1 (de) 2001-10-12 2002-10-11 Auf glucan-film basierte wirkstoffverabreichungssysteme

Country Status (6)

Country Link
EP (1) EP1463490B1 (de)
JP (1) JP4795639B2 (de)
AT (1) ATE536869T1 (de)
AU (2) AU2002332118B2 (de)
CA (1) CA2473975C (de)
WO (1) WO2003030881A1 (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030206942A1 (en) * 1998-09-25 2003-11-06 Neema Kulkarni Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent
US6596298B2 (en) 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US7666337B2 (en) 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
GB0217382D0 (en) * 2002-07-26 2002-09-04 Pfizer Ltd Process for making orally consumable dosage forms
GB0226076D0 (en) 2002-11-08 2002-12-18 Rp Scherer Technologies Inc Improved formulations containing substituted imidazole derivatives
FI20022007A0 (fi) 2002-11-08 2002-11-08 Juvantia Pharma Ltd Oy Oromukosaalinen valmiste ja menetelmä sen valmistamiseksi
US6669929B1 (en) 2002-12-30 2003-12-30 Colgate Palmolive Company Dentifrice containing functional film flakes
WO2004066986A1 (en) * 2003-01-30 2004-08-12 Monosolrx Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
JP2007526209A (ja) * 2003-04-14 2007-09-13 エフ　エム　シー　コーポレーション 均一かつ熱可逆性低粘度ポリマンナンフィルムの伝達システム
JP2006525308A (ja) * 2003-05-02 2006-11-09 ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー 耐熱性および耐湿性が改善された変性デンプンを含有する速溶性の経口消耗フィルム
US7666396B2 (en) * 2003-09-11 2010-02-23 Kimberly-Clark Worldwide, Inc. Single-use moisturizing product
US9248146B2 (en) 2003-10-24 2016-02-02 Adhesives Research, Inc. Dissolvable adhesive films for delivery of pharmaceutical or cosmetic agents
AU2004284080B2 (en) 2003-10-24 2008-10-02 Adhesives Research, Inc. Disintegratable films for diagnostic devices
US7972589B2 (en) 2004-05-17 2011-07-05 Akzo Nobel N.V. Hair fixative film
US7950399B2 (en) 2005-04-29 2011-05-31 Philip Morris Usa Inc. Non-tobacco pouch product
US9044049B2 (en) 2005-04-29 2015-06-02 Philip Morris Usa Inc. Tobacco pouch product
US20070042023A1 (en) * 2005-08-22 2007-02-22 National Starch And Chemical Investment Holding Corporation Dissolvable film
US8685478B2 (en) 2005-11-21 2014-04-01 Philip Morris Usa Inc. Flavor pouch
US20070190013A1 (en) * 2006-02-13 2007-08-16 Yeli Zhang Film and film-forming compositions
AU2007297697A1 (en) 2006-09-20 2008-03-27 Monosol Rx Llc Edible water-soluble film containing a foam reducing flavoring agent
WO2008089151A2 (en) * 2007-01-12 2008-07-24 Monosol Rx, Llc High dose film compositions and methods of preparation
US8616221B2 (en) 2007-02-28 2013-12-31 Philip Morris Usa Inc. Oral pouch product with flavored wrapper
FR2912915B1 (fr) * 2007-02-28 2012-11-16 Pf Medicament Film a desintegration rapide pour l'administration buccale de substances actives.
US20080220029A1 (en) * 2007-03-05 2008-09-11 Charlene Ng Fast-dissolving/disintegrating film preparation having high proportion of active
US9888712B2 (en) 2007-06-08 2018-02-13 Philip Morris Usa Inc. Oral pouch products including a liner and tobacco beads
US8950408B2 (en) 2007-07-16 2015-02-10 Philip Morris Usa Inc. Oral pouch product having soft edge
WO2009010884A2 (en) 2007-07-16 2009-01-22 Philip Morris Products S.A. Tobacco-free oral flavor delivery pouch product
US8377215B2 (en) 2008-12-18 2013-02-19 Philip Morris Usa Inc. Moist botanical pouch processing
US9027567B2 (en) 2008-12-30 2015-05-12 Philip Morris Usa Inc. Oral pouch product with multi-layered pouch wrapper
US8863755B2 (en) 2009-02-27 2014-10-21 Philip Morris Usa Inc. Controlled flavor release tobacco pouch products and methods of making
US8747562B2 (en) 2009-10-09 2014-06-10 Philip Morris Usa Inc. Tobacco-free pouched product containing flavor beads providing immediate and long lasting flavor release
TR201902233T4 (tr) 2009-10-30 2019-03-21 Ix Biopharma Ltd Hızlı çözünen katı dozaj formu.
US12186426B2 (en) 2009-10-30 2025-01-07 Ix Biopharma Ltd. Solid dosage form
EP2558370B1 (de) 2010-04-12 2017-04-05 Altria Client Services LLC Beutelprodukt mit verbesserter abdichtung und verfahren dafür
CA2807271C (en) 2010-06-10 2018-07-31 Midatech Limited Nanoparticle film delivery systems
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
FR2990349B1 (fr) 2012-05-11 2014-08-08 Pf Medicament Film monocouche a desintegration rapide et son utilisation dans l'hygiene buccale
WO2014116770A1 (en) 2013-01-23 2014-07-31 Arx, Llc Production of unit dose constructs
US9303918B2 (en) 2013-03-15 2016-04-05 Monosol Rx, Llc Process for drying a wet film with control of loss on drying
DE102014004533A1 (de) 2014-03-31 2015-10-01 Henkel Ag & Co. Kgaa Dosierungsform für Wasch- oder Reinigungsmittel
SG11201610547WA (en) * 2014-06-27 2017-01-27 Kao Corp Solid composition
JP7653218B2 (ja) 2016-05-05 2025-03-28 アクエスティブ セラピューティクス インコーポレイテッド 送達増強エピネフリン組成物
US12433850B2 (en) 2016-05-05 2025-10-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine and prodrug compositions
US12427121B2 (en) 2016-05-05 2025-09-30 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
KR102004901B1 (ko) * 2018-12-10 2019-07-29 김남이 미용성분 공급 및 피부노폐물 흡착의 이중 작용을 하는 건조 후 박리형 미용조성물을 이용한 미용시트세트
EP4119123A1 (de) 2021-07-14 2023-01-18 G.L. Pharma GmbH Oral zerfallende filmzusammensetzung mit buprenorphin
EP4119124B1 (de) 2021-07-14 2025-10-01 Vektor Pharma TF GmbH Mikroemulsion mit oral zerfallenden filmzusammensetzungen mit anpassbaren physikalischen und rheologischen eigenschaften
US12465564B2 (en) 2021-10-25 2025-11-11 Aquestive Therapeutics, Inc. Oral and nasal compositions and methods of treatment
CN119816555A (zh) 2022-11-18 2025-04-11 三菱化学株式会社 水溶性薄膜和其制造方法、药剂包装体和其制造方法
WO2025244060A1 (ja) * 2024-05-22 2025-11-27 三菱ケミカル株式会社 水溶性フィルム及びその製造方法、包装体、薬剤包装体及びその製造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562020A (en) * 1982-12-11 1985-12-31 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Process for producing self-supporting glucan film
JPS60219238A (ja) * 1984-04-14 1985-11-01 Hayashibara Biochem Lab Inc 徐崩性プルラン含有成形物とその製法
US4631837A (en) * 1985-05-31 1986-12-30 Magoon Richard E Method and apparatus for drying fruit pulp and the like
JPH0759496B2 (ja) * 1986-03-25 1995-06-28 ロ−ト製薬株式会社 歯周病治療剤
JPH0739508B2 (ja) * 1986-11-11 1995-05-01 株式会社林原生物化学研究所 プルラン・ポリエチレングリコ−ル会合物とその製造方法並びに用途
JP3232488B2 (ja) * 1992-08-20 2001-11-26 株式会社林原生物化学研究所 プルラン高含有物とその製造方法並びに用途
US5411945A (en) * 1992-08-29 1995-05-02 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Pullulan binder and its uses
US6596298B2 (en) * 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1

Also Published As

Publication number Publication date
JP4795639B2 (ja) 2011-10-19
CA2473975C (en) 2011-05-03
JP2005528328A (ja) 2005-09-22
EP1463490B1 (de) 2011-12-14
AU2008227076A1 (en) 2008-10-16
EP1463490A1 (de) 2004-10-06
CA2473975A1 (en) 2003-04-17
WO2003030881A1 (en) 2003-04-17
AU2002332118B2 (en) 2008-06-26

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