ATE538121T1 - 1,5,6-substituierte-2-oxo-3-cyano-1,6a- diazatetrahydrofluoranthene als antiinfektionsmittel - Google Patents

1,5,6-substituierte-2-oxo-3-cyano-1,6a- diazatetrahydrofluoranthene als antiinfektionsmittel

Info

Publication number
ATE538121T1
ATE538121T1 AT06707683T AT06707683T ATE538121T1 AT E538121 T1 ATE538121 T1 AT E538121T1 AT 06707683 T AT06707683 T AT 06707683T AT 06707683 T AT06707683 T AT 06707683T AT E538121 T1 ATE538121 T1 AT E538121T1
Authority
AT
Austria
Prior art keywords
diazatetrahydrofluoranthenes
antinifective
oxo
cyano
substituted
Prior art date
Application number
AT06707683T
Other languages
English (en)
Inventor
Bart Rudolf Romanie Kesteleyn
Pierre Jean-Marie Raboisson
De Vreken Wim Van
Maxime Francis Jean-Marie Ghislain Canard
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Application granted granted Critical
Publication of ATE538121T1 publication Critical patent/ATE538121T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/16—Peri-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT06707683T 2005-01-10 2006-01-10 1,5,6-substituierte-2-oxo-3-cyano-1,6a- diazatetrahydrofluoranthene als antiinfektionsmittel ATE538121T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05100092 2005-01-10
US68470605P 2005-05-26 2005-05-26
PCT/EP2006/050106 WO2006072636A2 (en) 2005-01-10 2006-01-10 1, 5, 6-substituted-2-oxo-3-cyano-1, 6a-diaza-tetrahydro-fluoranthenes as anti-infective agents

Publications (1)

Publication Number Publication Date
ATE538121T1 true ATE538121T1 (de) 2012-01-15

Family

ID=34938497

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06707683T ATE538121T1 (de) 2005-01-10 2006-01-10 1,5,6-substituierte-2-oxo-3-cyano-1,6a- diazatetrahydrofluoranthene als antiinfektionsmittel

Country Status (12)

Country Link
US (1) US7514427B2 (de)
EP (1) EP1838709B1 (de)
JP (1) JP2008526814A (de)
CN (1) CN101103029B (de)
AR (1) AR056918A1 (de)
AT (1) ATE538121T1 (de)
AU (1) AU2006204475B2 (de)
BR (1) BRPI0606475A2 (de)
CA (1) CA2584425A1 (de)
RU (1) RU2389730C2 (de)
TW (1) TW200637862A (de)
WO (1) WO2006072636A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR072534A1 (es) * 2008-07-25 2010-09-01 Gilead Sciences Inc Compuestos antivirales
WO2013020164A1 (en) * 2011-08-05 2013-02-14 Biota Scientific Management Pty Ltd Compounds for treating respiratory syncytial virus infections
US9975906B2 (en) 2014-05-16 2018-05-22 Shionogi & Co., Ltd. Tricyclic heterocycle derivatives having HIV replication inhibitory effect
TWI700284B (zh) * 2015-05-29 2020-08-01 日商塩野義製藥股份有限公司 具有ｈｉｖ複製抑制作用之含氮３環性衍生物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996038446A1 (en) * 1995-05-31 1996-12-05 Eisai Co., Ltd. Fused polycyclic heterocycle derivatives
DE19538088A1 (de) * 1995-10-13 1997-04-17 Bernd Prof Dr Clement Phenanthridinderivate und ihre Herstellung
EA009871B1 (ru) * 2002-11-15 2008-04-28 Тиботек Фармасьютикалз Лтд. Замещённые индолпиридиниевые соединения в качестве противоинфекционного средства

Also Published As

Publication number Publication date
CN101103029A (zh) 2008-01-09
CA2584425A1 (en) 2006-07-13
EP1838709B1 (de) 2011-12-21
US7514427B2 (en) 2009-04-07
WO2006072636A3 (en) 2006-12-14
TW200637862A (en) 2006-11-01
WO2006072636A2 (en) 2006-07-13
RU2007130550A (ru) 2009-02-20
JP2008526814A (ja) 2008-07-24
CN101103029B (zh) 2010-12-29
EP1838709A2 (de) 2007-10-03
AU2006204475B2 (en) 2011-03-10
BRPI0606475A2 (pt) 2009-06-30
US20080167296A1 (en) 2008-07-10
AR056918A1 (es) 2007-11-07
RU2389730C2 (ru) 2010-05-20
AU2006204475A1 (en) 2006-07-13

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