ATE538177T1 - Wundgele - Google Patents

Wundgele

Info

Publication number
ATE538177T1
ATE538177T1 AT01925748T AT01925748T ATE538177T1 AT E538177 T1 ATE538177 T1 AT E538177T1 AT 01925748 T AT01925748 T AT 01925748T AT 01925748 T AT01925748 T AT 01925748T AT E538177 T1 ATE538177 T1 AT E538177T1
Authority
AT
Austria
Prior art keywords
hydrogel
wounds
water
present
poloxamer
Prior art date
Application number
AT01925748T
Other languages
English (en)
Inventor
Mark Geoffrey Rippon
John Meadows
Original Assignee
Is Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Is Pharmaceuticals Ltd filed Critical Is Pharmaceuticals Ltd
Application granted granted Critical
Publication of ATE538177T1 publication Critical patent/ATE538177T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08Cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/60Liquid-swellable gel-forming materials, e.g. super-absorbents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02Polyalkylene oxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
AT01925748T 2000-05-08 2001-05-08 Wundgele ATE538177T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0011062A GB2362100B (en) 2000-05-08 2000-05-08 Wound gels
PCT/GB2001/002016 WO2001085845A1 (en) 2000-05-08 2001-05-08 Wound gels

Publications (1)

Publication Number Publication Date
ATE538177T1 true ATE538177T1 (de) 2012-01-15

Family

ID=9891176

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01925748T ATE538177T1 (de) 2000-05-08 2001-05-08 Wundgele

Country Status (6)

Country Link
US (1) US7083806B2 (de)
EP (1) EP1280857B1 (de)
AT (1) ATE538177T1 (de)
AU (1) AU5242701A (de)
GB (1) GB2362100B (de)
WO (1) WO2001085845A1 (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0120701D0 (en) * 2001-08-24 2001-10-17 Maelor Pharmaceuticals Ltd Pharmaceutical formulations
GB0127822D0 (en) * 2001-11-20 2002-01-09 Maelor Pharmaceuticals Ltd Medical dressings
US7465766B2 (en) 2004-01-08 2008-12-16 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US6982298B2 (en) * 2003-01-10 2006-01-03 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8137688B2 (en) 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8138265B2 (en) 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US7276037B2 (en) * 2003-03-27 2007-10-02 Sun Scientific, Inc. Compression apparatus for applying localized pressure to the venous system of the leg
US7559908B2 (en) * 2003-03-27 2009-07-14 Sundaram Ravikumar Compression apparatus for applying localized pressure to a wound or ulcer
US20040193084A1 (en) * 2003-03-27 2004-09-30 Arvik Enterprises, Llc Vein compressor device
JP2007509716A (ja) * 2003-10-29 2007-04-19 ジェンティス インコーポレイテッド 組織工学用の重合可能なエマルション
US7700086B2 (en) 2003-11-06 2010-04-20 Pluromed, Inc. Internal clamp for surgical procedures
US7351423B2 (en) * 2004-09-01 2008-04-01 Depuy Spine, Inc. Musculo-skeletal implant having a bioactive gradient
GB2409162B (en) * 2004-10-06 2005-12-14 Bhk Holding Ltd Materials,methods,and apparatus for treating a body cavity
ATE466602T1 (de) * 2005-02-14 2010-05-15 Yissum Res Dev Co Hydrogel-klebstoffe auf basis von depolymerisierten polysacchariden und verfahren zu dessen verwendung
EP1893174A2 (de) * 2005-05-10 2008-03-05 Cytophil, Inc. Injizierbare hydrogele und verfahren zu deren herstellung und anwendung
US20070086958A1 (en) * 2005-10-14 2007-04-19 Medafor, Incorporated Formation of medically useful gels comprising microporous particles and methods of use
CA2628295C (en) * 2005-11-02 2016-02-23 Birgit Riesinger Absorptive element to be mounted on human or animal skin surfaces
WO2008018892A2 (en) * 2005-12-22 2008-02-14 Pluromed, Inc. Methods and kits for treating lacerations and puncture wounds using inverse thermosensitive polymers
WO2007127392A2 (en) * 2006-04-27 2007-11-08 Pronovost Allan D Devices and methods for collecting oral samples of enriched serous fluid
US8608760B2 (en) * 2006-06-21 2013-12-17 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for joining non-conjoined lumens
US8197499B2 (en) * 2006-06-21 2012-06-12 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for joining non-conjoined lumens
CA2656179A1 (en) * 2006-06-21 2007-12-27 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for joining non-conjoined lumens
WO2008033728A2 (en) 2006-09-11 2008-03-20 Pluromed, Inc. Atraumatic occlusion balloons and skirts, and methods of use thereof
US7801502B2 (en) * 2006-12-18 2010-09-21 Aai Corporation Method for implementing continuous radio frequency (RF) alignment in advanced electronic warfare (EW) signal stimulation systems
CN100402086C (zh) * 2006-12-20 2008-07-16 张纲 碱性成纤维生长因子聚乳酸缓释纳米微球凝胶及其制备方法
WO2008088922A2 (en) * 2007-01-19 2008-07-24 Genentech, Inc. Prevention of hydrogel viscosity loss
EP2120561A4 (de) 2007-02-19 2012-11-21 Plurogen Therapeutics Inc Zusammensetzungen zur bearbeitung von biofolien und verfahren zu ihrer verwendung
DE502007003850D1 (de) * 2007-04-19 2010-07-01 August Wolff Gmbh & Co Kg Arzn Gel zur Behandlung von Wunden
US20100183519A1 (en) 2007-06-08 2010-07-22 University Of Virginia Patent Foundation Topical Poloxamer Formulations for Enhancing Microvascular Flow: Compositions and Uses Thereof
US20090124944A1 (en) * 2007-11-13 2009-05-14 Sundaram Ravikumar Method and Assembly for Treating Venous Ulcers and Wounds
WO2009070793A1 (en) * 2007-11-29 2009-06-04 Pluromed, Inc. Endoscopic mucosal resectioning using purified inverse thermosensitive polymers
WO2009086206A2 (en) * 2007-12-20 2009-07-09 Synvascular, Inc. Compositions and methods for joining non-conjoined lumens
US20090202467A1 (en) * 2008-02-08 2009-08-13 Bock Richard W Sclerotherapy for varicose veins
EP2249891B1 (de) 2008-02-13 2016-05-25 The Cleveland Clinic Foundation Molekulare verstärkung von extrazellulärer matrix und anwendungsverfahren
US8410180B2 (en) 2008-04-30 2013-04-02 The Cleveland Clinic Foundation Methods to treat urinary incontinence
KR101101321B1 (ko) * 2008-11-03 2012-01-02 주식회사 엠씨티티 상처 치유를 위한 하이드로 겔 형태의 세포전달용 비히클 및 그 제조방법
US8563037B2 (en) * 2009-02-06 2013-10-22 Tautona Group, L.P. Compositions and methods for joining non-conjoined lumens
US8980243B2 (en) 2009-05-19 2015-03-17 Neal Koller Surface active agent compositions and methods for enhancing oxygenation, reducing bacteria and improving wound healing at a site of treatment
CN102548538B (zh) * 2009-09-22 2014-03-12 V生命科学技术有限公司 治疗糖尿病足溃疡的局部制剂
CN102695501A (zh) 2009-11-09 2012-09-26 聚光灯技术合伙有限责任公司 碎裂水凝胶
CN106913902A (zh) 2009-11-09 2017-07-04 聚光灯技术合伙有限责任公司 多糖基水凝胶
US8409628B2 (en) 2010-02-04 2013-04-02 Penguin IP Holdings, Inc. Methods and compositions for oxygenation of skin to treat skin disorders
FR2956322A1 (fr) * 2010-02-17 2011-08-19 Urgo Lab Utilisation d'oligosaccharides polysulfates synthetiques comme agents de detersion d'une plaie.
WO2011123619A2 (en) 2010-03-31 2011-10-06 Penguin Ip Holdings Inc. Permeable mixtures, methods and compositions for the skin
US8499764B2 (en) 2010-05-26 2013-08-06 The Invention Science Fund I, Llc Portable apparatus for establishing an isolation field
FR2962046B1 (fr) * 2010-07-02 2012-08-17 Commissariat Energie Atomique Gel de decontamination biologique et procede de decontamination de surfaces utilisant ce gel.
US10279007B2 (en) 2010-11-15 2019-05-07 Oxygenetix Institute, Inc. Topical treatment method for healing wounds, disinfecting, covering and concealing the wound until healing occurs
PT2689774T (pt) * 2011-03-21 2019-04-05 Broda Tech Co Ltd Composições de hidrogel termo-reversíveis reversivamente
FR2975294B1 (fr) * 2011-05-20 2015-03-20 Oreal Composition cosmetique comprenant un polymere superabsorbant et un polyol a fort taux
FR2990364B1 (fr) 2012-05-11 2014-06-13 Commissariat Energie Atomique Procede de decontamination radioactive d'une terre par mousse de flottation a air disperse et ladite mousse
CN109260465A (zh) 2012-11-14 2019-01-25 史密夫和内修公司 稳定的嗜热菌蛋白酶水凝胶
RU2015137174A (ru) 2013-03-15 2017-04-24 Смит энд Невью, Инк. Растворимая образующая гель плёнка и способ очистки раны
WO2014168595A1 (en) * 2013-04-08 2014-10-16 Yeditepe Universitesi Polymer based hydrogel
GB2524299A (en) * 2014-03-19 2015-09-23 Medtrade Products Ltd Wound dressing
AU2016209327A1 (en) 2015-01-20 2017-08-10 Plurogen Therapeutics, Llc Compositions and methods of treating microbes
CN105664239B (zh) * 2016-03-23 2018-08-07 成都交大麦迪克科技有限公司 一种自粘附皮肤修复水凝胶的制备方法
EP3471701A4 (de) * 2016-06-21 2020-02-19 The Regents of the University of California Wundheilung mithilfe von braf-inhibitoren
CA3030466A1 (en) * 2016-07-12 2018-01-18 Centre National De La Recherche Scientifique Compositions useful for mucosal healing
CN108653718B (zh) * 2018-05-31 2022-03-11 广州润虹医药科技股份有限公司 一种可吸收促愈合止血组合物及敷料
CN110732037B (zh) 2018-07-20 2023-05-26 广州倍绣生物技术有限公司 止血糊剂及其制备方法
CN116390691A (zh) * 2020-08-10 2023-07-04 歌尔4梅德股份有限公司 自组装的两亲性肽水凝胶
CN115068666B (zh) * 2021-03-10 2023-12-26 广东粤港澳大湾区国家纳米科技创新研究院 一种防粘连的止血水凝胶及其制备方法和应用
CN115282329A (zh) * 2022-08-19 2022-11-04 河北农业大学 一种抗菌修复材料及其制备方法和应用
CA3268136A1 (en) * 2022-09-26 2024-04-04 Desentum Oy THERMOSENSITIVE HYDROGEL COMPOSITION

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1292640A (en) 1968-12-20 1972-10-11 Basf Wyandotte Corp Preparation of aqueous gel compositions containing a water-insoluble organic ingredient
SE440510B (sv) * 1980-06-11 1985-08-05 Ferrosan Ab Skumplast innehallande svellbara polymerpartiklar samt sett for framstellning derav
US5057308A (en) * 1986-11-06 1991-10-15 Hill Ira D Method of treating the oral cavity with oral hygiene preparations containing active SnF2
US5013769A (en) * 1988-08-22 1991-05-07 Medipro Sciences Limited Method of making a hydrogel-forming wound dressing or skin coating material
US4920158A (en) * 1989-10-11 1990-04-24 Medipro Sciences Limited Hydrogel-forming wound dressing or skin coating material
CA1339682C (en) * 1989-09-29 1998-02-24 Douglas G. Murray Hydrogel-forming wound dressing or skin coating material
US5346703A (en) * 1990-08-07 1994-09-13 Mediventures, Inc. Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
CA2044878C (en) * 1990-08-07 2000-12-26 Tacey X. Viegas Thermally reversible and irreversible gels
US5124151A (en) * 1990-08-07 1992-06-23 Mediventures Inc. Drug delivery by injection with thermo-irreversible gels
US5071644A (en) * 1990-08-07 1991-12-10 Mediventures, Inc. Topical drug delivery with thermo-irreversible gels
US5143731A (en) * 1990-08-07 1992-09-01 Mediventures Incorporated Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
US5077033A (en) * 1990-08-07 1991-12-31 Mediventures Inc. Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide
US5376693A (en) * 1990-08-07 1994-12-27 Mediventures Inc. Thermo-irreversible gel corneal contact lens formed in situ
US5847023A (en) * 1990-10-26 1998-12-08 Mdv Technologies, Inc. Thermal irreversible gel corneal contact lens formed in situ
HUT67319A (en) 1991-08-30 1995-03-28 Life Medical Sciences Inc Compositions for treating wounds
US5496541C1 (en) * 1993-01-19 2001-06-26 Squigle Inc Tasteful toothpaste and other dental products
US5849405A (en) * 1994-08-31 1998-12-15 The Procter & Gamble Company Absorbent materials having improved absorbent property and methods for making the same
US5843575A (en) * 1994-02-17 1998-12-01 The Procter & Gamble Company Absorbent members comprising absorbent material having improved absorbent property
CN1141005A (zh) * 1994-02-17 1997-01-22 普罗克特和甘保尔公司 具有改性表面性能的吸收性材料及其制备方法
US5603955A (en) * 1994-07-18 1997-02-18 University Of Cincinnati Enhanced loading of solutes into polymer gels
US5840338A (en) * 1994-07-18 1998-11-24 Roos; Eric J. Loading of biologically active solutes into polymer gels
US5814031A (en) * 1995-03-02 1998-09-29 Mooney; Mark Structured occllusive dressings
EP0771848B1 (de) * 1995-04-27 2004-02-18 Polyplastics Co. Ltd. Thermoplastische harzzusammensetzung und verfahren zu ihrer herstellung
US5942478A (en) * 1995-09-19 1999-08-24 Lopes; John A. Microbicidal and sanitizing soap compositions
ATE264119T1 (de) 1996-07-11 2004-04-15 Coloplast As Hydrokolloid-wundgel

Also Published As

Publication number Publication date
AU5242701A (en) 2001-11-20
US7083806B2 (en) 2006-08-01
GB0011062D0 (en) 2000-06-28
GB2362100B (en) 2002-05-08
EP1280857A1 (de) 2003-02-05
US20040028739A1 (en) 2004-02-12
WO2001085845A1 (en) 2001-11-15
GB2362100A (en) 2001-11-14
EP1280857B1 (de) 2011-12-21
WO2001085845B1 (en) 2002-03-21

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