ATE539078T1 - Isoxazolderivate enthaltende pharmazeutische zusammensetzung zur prävention und behandlung von restenose - Google Patents

Isoxazolderivate enthaltende pharmazeutische zusammensetzung zur prävention und behandlung von restenose

Info

Publication number
ATE539078T1
ATE539078T1 AT08778486T AT08778486T ATE539078T1 AT E539078 T1 ATE539078 T1 AT E539078T1 AT 08778486 T AT08778486 T AT 08778486T AT 08778486 T AT08778486 T AT 08778486T AT E539078 T1 ATE539078 T1 AT E539078T1
Authority
AT
Austria
Prior art keywords
pharmaceutical composition
prevention
treatment
isoxazole derivatives
restenoses
Prior art date
Application number
AT08778486T
Other languages
English (en)
Inventor
Sun Gwan Hwang
Sang Rak Choi
Jeong Woo Cho
Sung Jin Bae
Tae Sung Koo
So Young Lee
Kyung Chul Cho
Hyeon Cheol Gwon
Original Assignee
Sk Holdings Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sk Holdings Co Ltd filed Critical Sk Holdings Co Ltd
Application granted granted Critical
Publication of ATE539078T1 publication Critical patent/ATE539078T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT08778486T 2007-06-29 2008-06-30 Isoxazolderivate enthaltende pharmazeutische zusammensetzung zur prävention und behandlung von restenose ATE539078T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20070065481 2007-06-29
KR1020080062297A KR101464302B1 (ko) 2007-06-29 2008-06-30 아이속사졸 유도체를 포함하는 혈관재협착 예방 및 치료용약학 조성물
PCT/KR2008/003821 WO2009005269A2 (en) 2007-06-29 2008-06-30 Pharmaceutical composition for preventintion and treatment of restenosis comprising isoxazole derivatives

Publications (1)

Publication Number Publication Date
ATE539078T1 true ATE539078T1 (de) 2012-01-15

Family

ID=40486904

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08778486T ATE539078T1 (de) 2007-06-29 2008-06-30 Isoxazolderivate enthaltende pharmazeutische zusammensetzung zur prävention und behandlung von restenose

Country Status (8)

Country Link
US (1) US8518978B2 (de)
EP (1) EP2170876B1 (de)
JP (1) JP5311075B2 (de)
KR (1) KR101464302B1 (de)
CN (1) CN101778845B (de)
AT (1) ATE539078T1 (de)
ES (1) ES2379746T3 (de)
WO (1) WO2009005269A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101778845B (zh) 2007-06-29 2014-06-25 爱思开生物制药株式会社 用于预防和治疗再狭窄的包含异噁唑衍生物的药物组合物
CA2764339A1 (en) * 2009-06-05 2010-12-09 Oslo University Hospital Hf Azole derivatives as wtn pathway inhibitors
RU2013128448A (ru) 2010-12-08 2015-01-20 Осло Юниверсити Хоспитал Хф Производные триазола в качестве ингибиторов сигнального пути wnt
US10441687B2 (en) * 2013-11-13 2019-10-15 Albert Einstein College Of Medicine Wnt/beta-catenin inhibitor-eluting endovascular stent
WO2015138934A1 (en) 2014-03-13 2015-09-17 Proteostasis Therapeutics, Inc. Compounds, compositions, and methods for increasing cftr activity
CA2942386A1 (en) 2014-03-13 2015-09-17 Proteostasis Therapeutics, Inc. Compounds, compositions, and methods for increasing cftr activity
CA2952862A1 (en) 2014-06-19 2015-12-23 Proteostasis Therapeutics, Inc. Compounds, compositions and methods of increasing cftr activity
WO2016086092A1 (en) 2014-11-25 2016-06-02 The Penn State Research Foundation Chemical reprogramming of human glial cells into neurons for brain and spinal cord repair
CA2971850A1 (en) 2014-12-23 2016-06-30 Proteostasis Therapeutics, Inc. Derivatives of 5-phenyl- or 5-heteroarylthiazol-2-carboxylic amide useful for the treatment of inter alia cystic fibrosis
MA41253A (fr) 2014-12-23 2017-10-31 Proteostasis Therapeutics Inc Composés, compositions et procédés pour augmenter l'activité du cftr
WO2016105468A1 (en) * 2014-12-23 2016-06-30 Proteostasis Therapeutics, Inc. Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis
US10738011B2 (en) 2014-12-23 2020-08-11 Proteostasis Therapeutics, Inc. Derivatives of 5-(hetero)arylpyrazol-3-carboxylic amide or 1-(hetero)aryltriazol-4-carboxylic amide useful for the treatment of inter alia cystic fibrosis
MA42488A (fr) 2015-07-24 2018-05-30 Proteostasis Therapeutics Inc Composés, compositions et procédés pour augmenter l'activité du cftr
CA3000483C (en) 2015-10-06 2024-02-13 Proteostasis Therapeutics, Inc. Compounds, compositions, and methods for modulating cftr
CN107056754B (zh) * 2015-12-07 2020-12-04 苏州信诺维医药科技有限公司 内嵌脲类结构的wnt通路抑制剂
BR112018070747B1 (pt) 2016-04-07 2024-01-09 Proteostasis Therapeutics, Inc Átomos de silicone contendo análogos de ivacaftor, composições farmacêuticas e usos terapêuticos
MA45397A (fr) 2016-06-21 2019-04-24 Proteostasis Therapeutics Inc Composés, compositions et procédés pour augmenter l'activité du cftr
CA3162888A1 (en) * 2019-11-25 2021-06-03 The Penn State Research Foundation Chemotherapy for glioma through neuronal conversion
CN117751182A (zh) * 2021-05-18 2024-03-22 南加利福尼亚大学 用于扩增人粒细胞-巨噬细胞祖细胞的方法及其应用
CN116554461B (zh) * 2022-01-29 2026-03-31 华东理工大学 聚合物在促进介入/植入材料内皮化中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002342607B2 (en) * 2001-08-06 2006-10-19 Pharmacia Italia S.P.A. Aminoisoxazole derivatives active as kinase inhibitors
KR101394245B1 (ko) * 2005-12-30 2014-05-14 에스케이바이오팜 주식회사 아이속사졸 유도체 및 이의 용도
WO2008070739A1 (en) * 2006-12-06 2008-06-12 Cytokinetics, Inc. Ksp activators
CN101778845B (zh) 2007-06-29 2014-06-25 爱思开生物制药株式会社 用于预防和治疗再狭窄的包含异噁唑衍生物的药物组合物

Also Published As

Publication number Publication date
US20110028506A1 (en) 2011-02-03
ES2379746T3 (es) 2012-05-03
JP2010532344A (ja) 2010-10-07
CN101778845B (zh) 2014-06-25
KR20090004612A (ko) 2009-01-12
EP2170876B1 (de) 2011-12-28
EP2170876A4 (de) 2010-10-27
WO2009005269A2 (en) 2009-01-08
EP2170876A2 (de) 2010-04-07
US8518978B2 (en) 2013-08-27
WO2009005269A3 (en) 2009-02-26
JP5311075B2 (ja) 2013-10-09
KR101464302B1 (ko) 2014-11-26
CN101778845A (zh) 2010-07-14

Similar Documents

Publication Publication Date Title
ATE539078T1 (de) Isoxazolderivate enthaltende pharmazeutische zusammensetzung zur prävention und behandlung von restenose
ATE376828T1 (de) Verwendung von rotigotin zur behandlung und prävention des parkinson-plus-syndroms
EA200800798A1 (ru) Фармацевтические композиции, предназначенные для лечения нарушений внутреннего уха
MX2008013836A (es) Derivados de 2-piridona para el tratamiento de enfermedades o condiciones en las cuales es benefica la inhibicion de la actividad de elastasa de neutrofilos.
TNSN08070A1 (en) Benzoquinazoline derivatives and their use in treating bone disorders
MX2013013809A (es) Dispositivos expandibles con revestimiento de una composicion de paclitaxel.
ATE534377T1 (de) Verfahren und zusammensetzungen zur behandlung von hämatologischen erkrankungen
ATE502633T1 (de) Cyclosporins zur behandlung und vorbeugung von augenerkrankungen
EA200802223A1 (ru) 1,5-дифенилпиразолы ii в качестве ингибиторов hsp90
BR0313747A (pt) Inibidores de transcriptase reversa de não-nucleosìdeo
ECSP088869A (es) Derivados de 2-pirazinona para el tratamiento de enfermedades o condiciones en donde resulta beneficiosa la inhibición de la actividad de la elastasa neutrofílica
ATE456369T1 (de) Flibanserin zur behandlung von harninkontinenz und assoziierten erkrankungen
DE602008004540D1 (de) 2-oxo-2-(2-phenyl-5,6,7,8-tetrahydroindolizin-3-yl)acetamidderivate und verwandte verbindungen als antipilzmittel
NO20083758L (no) Nye terapautiske kombinasjoner for behandling av depresjon
TW200806299A (en) Treatment of pain
SG178975A1 (en) Indenone derivative and pharmaceutical composition comprising same
EA201071006A1 (ru) Набор, композиция, продукт или лекарственное средство для лечения нарушения познавательной способности
EP1921077A4 (de) Mittel zur behandlung und/oder prävention von schlafstörungen
DE502005008058D1 (de) Gesättigte und ungesättigte 3-pyridyl-benzocycloalkylmethyl-amine zur behandlung von schmerzen, depressionen und angstzuständen
DE602007011975D1 (de) Thiadiazolderivate zur behandlung neurodegenerativer krankheiten
ATE447948T1 (de) Verwendung von benzokondensierten heterocyclischen sulfamid-derivaten zur behandlung von schmerzen
MX2013013808A (es) Dispositivos expandibles con revestimiento de una composicion de rapamicina.
ATE541567T1 (de) Pharmazeutische zusammensetzung zur prävention und behandlung von metabolischen knochenerkrankungen mit alpha-arylmethoxyacrylat- derivaten
EA200870223A1 (ru) Производные бензоизоиндола для лечения боли
ATE556053T1 (de) Piperidinderivate zur behandlung von alzheimer- krankheit