ATE539086T1 - Interleukin-11-fusionsproteine - Google Patents

Interleukin-11-fusionsproteine

Info

Publication number: ATE539086T1
Authority: AT; Austria
Prior art keywords: fusion proteins; albumin; nucleic acids; albumin fusion; vectors
Prior art date: 2003-12-03

Application number

AT04805919T

Other languages

English (en)

Inventor

Monika Kroez

Gerhard Dickneite

Hans-Peter Hauser

Thomas Weimer

Darrell Sleep

Original Assignee

Monika Kroez

Thomas Weimer

Hans-Peter Hauser

Gerhard Dickneite

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-03

Filing date

2004-12-03

Publication date

2012-01-15

2004-12-03 Application filed by Monika Kroez, Thomas Weimer, Hans-Peter Hauser, Gerhard Dickneite filed Critical Monika Kroez

2012-01-15 Application granted granted Critical

2012-01-15 Publication of ATE539086T1 publication Critical patent/ATE539086T1/de

Links

102000037865 fusion proteins Human genes 0.000 title abstract 7
108020001507 fusion proteins Proteins 0.000 title abstract 7
102000003815 Interleukin-11 Human genes 0.000 title abstract 3
108090000177 Interleukin-11 Proteins 0.000 title abstract 3
229940074383 interleukin-11 Drugs 0.000 title abstract 3
102000009027 Albumins Human genes 0.000 abstract 6
108010088751 Albumins Proteins 0.000 abstract 6
102000039446 nucleic acids Human genes 0.000 abstract 4
108020004707 nucleic acids Proteins 0.000 abstract 4
150000007523 nucleic acids Chemical class 0.000 abstract 4
239000013598 vector Substances 0.000 abstract 3
239000012634 fragment Substances 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 2
230000001225 therapeutic effect Effects 0.000 abstract 2
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
206010043554 thrombocytopenia Diseases 0.000 abstract 1
230000001361 thrombopoietic effect Effects 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2073—IL-11
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5431—IL-11
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Toxicology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Epidemiology (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Hematology (AREA)
Diabetes (AREA)
Obesity (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AT04805919T 2003-12-03 2004-12-03 Interleukin-11-fusionsproteine ATE539086T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP03027770		2003-12-03
PCT/GB2004/005091 WO2005054286A2 (en)	2003-12-03	2004-12-03	Interleukin-11 fusion proteins

Publications (1)

Publication Number	Publication Date
ATE539086T1 true ATE539086T1 (de)	2012-01-15

Family

ID=34639273

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04805919T ATE539086T1 (de)	2003-12-03	2004-12-03	Interleukin-11-fusionsproteine

Country Status (9)

Country	Link
US (3)	US20080292581A1 (de)
EP (1)	EP1704164B1 (de)
CN (1)	CN1938333A (de)
AT (1)	ATE539086T1 (de)
AU (1)	AU2004295171A1 (de)
CA (1)	CA2565173A1 (de)
ES (1)	ES2380022T3 (de)
WO (1)	WO2005054286A2 (de)
ZA (1)	ZA200605449B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1957097A1 (de) *	2005-12-06	2008-08-20	Wyeth a Corporation of the State of Delaware	Interleukin-11-zusammensetzungen und anwendungsverfahren
BR112014001274A2 (pt)	2011-07-18	2017-04-18	Arts Biologics As	composto de hormônio luteinizante, e, composição farmacêutica
US20150133383A1 (en)	2012-05-11	2015-05-14	Prorec Bio Ab	Method for diagnosis and treatment of prolactin associated disorders
WO2015001049A1 (en)	2013-07-04	2015-01-08	Novartis Ag	O-mannosyltransferase deficient filamentous fungal cells and methods of use thereof
CN105198999A (zh) *	2014-05-27	2015-12-30	上海生物制品研究所有限责任公司	一种融合蛋白、其制备方法及其应用
SG11201700446XA (en)	2014-07-21	2017-02-27	Glykos Finland Oy	Production of glycoproteins with mammalian-like n-glycans in filamentous fungi
CN111116729B (zh) *	2019-12-30	2020-09-08	深圳市中康联大健康生物科技有限公司	白细胞介素11突变体及其在治疗肝纤维化中的应用
CN114561395B (zh) *	2022-03-30	2023-07-28	四川大学	无融合标签的rhIL-11及其突变体的可溶表达及高效纯化方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4736866B1 (en) *	1984-06-22	1988-04-12		Transgenic non-human mammals
US5576195A (en) *	1985-11-01	1996-11-19	Xoma Corporation	Vectors with pectate lyase signal sequence
US4857467A (en) *	1986-07-23	1989-08-15	Phillips Petroleum Company	Carbon and energy source markers for transformation of strains of the genes Pichia
JP2873012B2 (ja) *	1987-04-09	1999-03-24	デルタバイオテクノロジーリミテッド	酵母ベクター
US5641670A (en) *	1991-11-05	1997-06-24	Transkaryotic Therapies, Inc.	Protein production and protein delivery
US5489743A (en) *	1993-01-19	1996-02-06	Amgen Inc.	Transgenic animal models for thrombocytopenia
US6540993B1 (en) *	1995-06-27	2003-04-01	Wyeth	Method of treating inflammatory bowel disease using a topical formulation of IL-11
GB9902000D0 (en)	1999-01-30	1999-03-17	Delta Biotechnology Ltd	Process
EP2213743A1 (de) *	2000-04-12	2010-08-04	Human Genome Sciences, Inc.	Albuminfusionsproteine
US7176278B2 (en) *	2001-08-30	2007-02-13	Biorexis Technology, Inc.	Modified transferrin fusion proteins
AU2002323501C1 (en) *	2001-08-30	2010-04-29	Biorexis Technology, Inc	Modified transferrin fusion proteins
AU2002332041A1 (en) *	2001-10-05	2003-04-22	Human Genome Sciences, Inc.	Albumin fusion proteins
AU2002364586A1 (en) *	2001-12-21	2003-07-30	Delta Biotechnology Limited	Albumin fusion proteins
WO2003059934A2 (en) *	2001-12-21	2003-07-24	Human Genome Sciences, Inc.	Albumin fusion proteins
CN1241946C (zh) *	2002-07-01	2006-02-15	美国福源集团	对多种细胞具刺激增生作用的人血清白蛋白重组融合蛋白

2004
- 2004-12-03 ES ES04805919T patent/ES2380022T3/es not_active Expired - Lifetime
- 2004-12-03 AT AT04805919T patent/ATE539086T1/de active
- 2004-12-03 EP EP04805919A patent/EP1704164B1/de not_active Expired - Lifetime
- 2004-12-03 WO PCT/GB2004/005091 patent/WO2005054286A2/en not_active Ceased
- 2004-12-03 CA CA002565173A patent/CA2565173A1/en not_active Abandoned
- 2004-12-03 AU AU2004295171A patent/AU2004295171A1/en not_active Abandoned
- 2004-12-03 CN CNA200480041355XA patent/CN1938333A/zh active Pending
- 2004-12-03 US US10/584,438 patent/US20080292581A1/en not_active Abandoned
- 2004-12-03 ZA ZA200605449A patent/ZA200605449B/en unknown
2009
- 2009-11-25 US US12/626,107 patent/US20100143973A1/en not_active Abandoned
2011
- 2011-10-21 US US13/278,757 patent/US20120258072A1/en not_active Abandoned

Also Published As

Publication number	Publication date
ES2380022T3 (es)	2012-05-07
US20100143973A1 (en)	2010-06-10
EP1704164B1 (de)	2011-12-28
EP1704164A2 (de)	2006-09-27
AU2004295171A1 (en)	2005-06-16
CN1938333A (zh)	2007-03-28
US20120258072A1 (en)	2012-10-11
US20080292581A1 (en)	2008-11-27
WO2005054286A3 (en)	2006-11-30
WO2005054286A2 (en)	2005-06-16
ZA200605449B (en)	2007-11-28
CA2565173A1 (en)	2005-06-16

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JP2023011696A (ja)	2023-01-24	核酸産物およびその投与方法
EP2277889A3 (de)	2011-04-27	Fusionsproteine von Albumin und Interferon beta
ECSP088262A (es)	2008-05-30	Proteínas de fusión de albúmina
WO2005077042A3 (en)	2006-11-30	Albumin fusion proteins
EA200800368A1 (ru)	2008-06-30	Гликозилированный il-7, получение и применение
WO2001079442A3 (en)	2002-06-06	Albumin fusion proteins
WO2007104529A3 (en)	2007-12-13	Amino acid sequences directed against il-6 and polypeptides comprising the same for the treatment of diseases and disorders associated with il-6-mediated signalling
EA200400476A1 (ru)	2004-08-26	Производные аминоиндазола, активные в качестве ингибиторов киназ, способ их получения и содержащая их фармацевтическая композиция
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ATE360031T1 (de)	2007-05-15	Chimäre proteine und anwendungen
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WO2022256500A3 (en)	2023-01-19	Dll3 targeting trispecific proteins and methods of use
DK1278868T3 (da)	2008-05-19	Muteret form af arginindeiminase
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ATE539086T1 (de)	2012-01-15	Interleukin-11-fusionsproteine
US20090263355A1 (en)	2009-10-22	Deamidated interferon-beta
ATE501728T1 (de)	2011-04-15	Therapeutische verwendung von lpi, einem inhibitor des lectinwegs in staphylokokken bei entzündungskrankheiten
DK1373529T3 (da)	2008-08-18	Tau-opati model
ES2208691T3 (es)	2004-06-16	Modificacion gradual, superagonistas o antagonistas de proteinas y peptidos señal.
Kahroba et al.	2016	Simplified Method to Produce Human Bioactive Leukemia Inhibitory Factor in Escherichia coli
UA85995C2 (ru)	2009-03-25	Химерическое антитело, которое специфически связывается с человеческим il-6, и фармацевтическая композиция, которая его содержит
JP2002348254A5 (de)	2005-09-08