ATE539330T1 - Mikroskopische vorrichtung und verfahren mittels polarisierter kohärenter anti-stokes- ramanstreuung - Google Patents

Mikroskopische vorrichtung und verfahren mittels polarisierter kohärenter anti-stokes- ramanstreuung

Info

Publication number
ATE539330T1
ATE539330T1 AT02759148T AT02759148T ATE539330T1 AT E539330 T1 ATE539330 T1 AT E539330T1 AT 02759148 T AT02759148 T AT 02759148T AT 02759148 T AT02759148 T AT 02759148T AT E539330 T1 ATE539330 T1 AT E539330T1
Authority
AT
Austria
Prior art keywords
electromagnetic field
polarized electromagnetic
frequency
stokes
scattering
Prior art date
Application number
AT02759148T
Other languages
English (en)
Inventor
Xiaoliang Xie
Ji-Xin Cheng
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Application granted granted Critical
Publication of ATE539330T1 publication Critical patent/ATE539330T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Spectrometry And Color Measurement (AREA)
AT02759148T 2001-07-03 2002-06-27 Mikroskopische vorrichtung und verfahren mittels polarisierter kohärenter anti-stokes- ramanstreuung ATE539330T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30292801P 2001-07-03 2001-07-03
PCT/US2002/022296 WO2003004983A1 (en) 2001-07-03 2002-06-27 System and method for polarization coherent anti-stokes raman scattering microscopy

Publications (1)

Publication Number Publication Date
ATE539330T1 true ATE539330T1 (de) 2012-01-15

Family

ID=23169832

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02759148T ATE539330T1 (de) 2001-07-03 2002-06-27 Mikroskopische vorrichtung und verfahren mittels polarisierter kohärenter anti-stokes- ramanstreuung

Country Status (5)

Country Link
US (1) US6798507B2 (de)
EP (1) EP1405049B1 (de)
JP (1) JP4212471B2 (de)
AT (1) ATE539330T1 (de)
WO (1) WO2003004983A1 (de)

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EP1853885A4 (de) 2005-01-21 2011-10-05 Harvard College Abstimmbarer optischer parametrischer oszillator für die nichtlineare vibrations-spektroskopie
WO2006132967A2 (en) * 2005-06-03 2006-12-14 Massachusetts Institute Of Technology Method and apparatus for frequency-converting infrared light
DE102005044422A1 (de) * 2005-09-16 2007-03-29 Carl Zeiss Jena Gmbh Kohärente anti-Stokes'sche Ramanstreuungs-(CARS)-Mikroskopie
US7414729B2 (en) * 2005-10-13 2008-08-19 President And Fellows Of Harvard College System and method for coherent anti-Stokes Raman scattering endoscopy
US7573577B2 (en) 2005-10-21 2009-08-11 Southwest Research Institute Spatial heterodyne wide-field Coherent Anti-Stokes Raman spectromicroscopy
US7352458B2 (en) * 2005-10-26 2008-04-01 President And Fellows Of Harvard College System and method for high sensitivity vibrational imaging with frequency modulation coherent anti-stokes Raman scattering analyses
US7659977B2 (en) * 2006-04-21 2010-02-09 Intel Corporation Apparatus and method for imaging with surface enhanced coherent anti-stokes raman scattering (SECARS)
EP2074661A4 (de) * 2006-10-27 2012-03-07 Aretais Inc Verwendung von quantensystemidentifikations- und quantensteuertechniken für medizinische diagnose und therapeutische zwecke
WO2008052221A2 (en) * 2006-10-27 2008-05-02 Aretais, Inc. Use of coherent raman techniques for medical diagnostic and therapeutic purposes, and calibration techniques for same
US7480045B2 (en) * 2006-10-31 2009-01-20 Academia Sinica Controlling pulses in optical microscopy
US7869051B2 (en) * 2007-01-19 2011-01-11 Stc. Unm System and method for ratiometric non-linear coherent imaging
DE102007021378A1 (de) * 2007-05-04 2008-11-06 Ape Angewandte Physik Und Elektronik Gmbh Verfahren und optische Anordnung zum Erzeugen eines nicht-linearen optischen Signals an einem durch ein Anregungsfeld angeregten Material sowie Verwendung des Verfahrens und der optischen Anordnung
KR100829439B1 (ko) * 2007-06-08 2008-05-15 한국표준과학연구원 적외선 사광파 혼합 편광 이미징 장치
DE102007048135B4 (de) * 2007-10-05 2012-02-16 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Fluoreszenzlichtmikroskopisches Messen einer Probe mit rotverschobenen Stokes-Linien
US8027032B2 (en) * 2008-08-22 2011-09-27 President & Fellows Of Harvard College Microscopy imaging system and method employing stimulated raman spectroscopy as a contrast mechanism
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US9285575B2 (en) * 2009-01-26 2016-03-15 President And Fellows Of Harvard College Systems and methods for selective detection and imaging in coherent Raman microscopy by spectral excitation shaping
US8675201B2 (en) * 2009-06-05 2014-03-18 The Penn State Research Foundation Coherent anti-Stokes Raman holography
FI20096067A0 (fi) 2009-10-15 2009-10-15 Valtion Teknillinen Raman-säteilyn mittaus
WO2011162787A1 (en) 2010-06-22 2011-12-29 President And Fellows Of Harvard College Systems and methods providing efficient detection of back-scattered illumination in modulation transfer microscopy or micro-spectroscopy
GB201013321D0 (en) * 2010-08-06 2010-09-22 King S College London Method and apparatus for non-resonant background reduction in Coherent anti-strokes Raman Scattering (CARS) spectroscopy
CN102359764B (zh) * 2011-08-18 2013-07-24 天津大学 基于碳纳米管为传感介质的平面变形无损检测装置
US9581497B2 (en) 2012-10-19 2017-02-28 Hitachi, Ltd. Cars microscope
FR3003949B1 (fr) * 2013-03-26 2015-05-01 Univ Aix Marseille Dispositif et methode de detection raman stimulee.
CN106546572B (zh) * 2015-12-13 2018-06-19 中国科学院大连化学物理研究所 一种短波长激光手性拉曼光谱仪
DE102015225871B4 (de) 2015-12-18 2017-07-27 Carl Zeiss Microscopy Gmbh Verfahren der Stimulierten Raman-Mikroskopie und Mikroskop
US10515474B2 (en) * 2017-01-19 2019-12-24 Mindmaze Holding Sa System, method and apparatus for detecting facial expression in a virtual reality system
WO2018174244A1 (ja) * 2017-03-23 2018-09-27 アトナープ株式会社 光学ヘッドおよび計測装置
KR102402681B1 (ko) * 2020-04-17 2022-05-26 한국과학기술원 다광자 현미경, 그리고 이의 시간 게이트 검출 기반 이미징 방법
CN112462507B (zh) * 2020-10-22 2022-05-10 北京航空航天大学 抑制相干反斯托克斯拉曼散射显微镜非共振背景信号的方法、成像方法及系统

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Also Published As

Publication number Publication date
JP2004534232A (ja) 2004-11-11
EP1405049B1 (de) 2011-12-28
WO2003004983A1 (en) 2003-01-16
EP1405049A1 (de) 2004-04-07
US20030011765A1 (en) 2003-01-16
JP4212471B2 (ja) 2009-01-21
US6798507B2 (en) 2004-09-28

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