ATE539743T1 - Verfahren zur prävention und behandlung von ppar- vermittelten zuständen mit macelignan - Google Patents
Verfahren zur prävention und behandlung von ppar- vermittelten zuständen mit macelignanInfo
- Publication number
- ATE539743T1 ATE539743T1 AT06769069T AT06769069T ATE539743T1 AT E539743 T1 ATE539743 T1 AT E539743T1 AT 06769069 T AT06769069 T AT 06769069T AT 06769069 T AT06769069 T AT 06769069T AT E539743 T1 ATE539743 T1 AT E539743T1
- Authority
- AT
- Austria
- Prior art keywords
- macelignan
- preventing
- mediated conditions
- treating ppar
- ppar
- Prior art date
Links
- QDDILOVMGWUNGD-UONOGXRCSA-N 4-[(2S,3R)-4-(1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol Chemical compound C1=C(O)C(OC)=CC(C[C@H](C)[C@H](C)CC=2C=C3OCOC3=CC=2)=C1 QDDILOVMGWUNGD-UONOGXRCSA-N 0.000 title abstract 2
- QDDILOVMGWUNGD-UHFFFAOYSA-N Macelignan Natural products C1=C(O)C(OC)=CC(CC(C)C(C)CC=2C=C3OCOC3=CC=2)=C1 QDDILOVMGWUNGD-UHFFFAOYSA-N 0.000 title abstract 2
- 208000002249 Diabetes Complications Diseases 0.000 abstract 2
- 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 abstract 2
- 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 abstract 2
- 206010012655 Diabetic complications Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Paper (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020050055539A KR100627643B1 (ko) | 2005-06-27 | 2005-06-27 | 제 2 형 당뇨병 치료 또는 예방용 약제학적 조성물 |
| KR1020050056692A KR20070001326A (ko) | 2005-06-29 | 2005-06-29 | 핵수용체 피피에이알감마의 신규한 리간드 |
| KR20050087991 | 2005-09-22 | ||
| PCT/KR2006/002493 WO2007001150A2 (en) | 2005-06-27 | 2006-06-27 | Method for preventing and treating conditions mediated by ppar using macelignan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE539743T1 true ATE539743T1 (de) | 2012-01-15 |
Family
ID=37595537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06769069T ATE539743T1 (de) | 2005-06-27 | 2006-06-27 | Verfahren zur prävention und behandlung von ppar- vermittelten zuständen mit macelignan |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7902254B1 (de) |
| EP (1) | EP1948161B1 (de) |
| JP (1) | JP5416969B2 (de) |
| CN (1) | CN102036662B (de) |
| AT (1) | ATE539743T1 (de) |
| ES (1) | ES2380556T3 (de) |
| WO (1) | WO2007001150A2 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100844376B1 (ko) * | 2007-02-07 | 2008-07-07 | 한국화학연구원 | 육두구 추출물 또는 이로부터 분리된 활성 화합물을포함하는 골다공증 예방 또는 치료용 조성물 |
| KR101404398B1 (ko) * | 2007-06-20 | 2014-06-09 | (주)뉴트리 | 주름개선 화장료 조성물 |
| KR101088071B1 (ko) * | 2007-10-17 | 2011-11-29 | (주)뉴트리 | 리그난계 화합물 또는 이를 함유하는 육두구 추출물 또는 육두구 가종피 추출물의 신규한 용도 |
| EP3228320B1 (de) | 2008-10-17 | 2019-12-18 | Sanofi-Aventis Deutschland GmbH | Kombination von einem insulin und einem glp-1-agonisten |
| WO2010064845A2 (en) * | 2008-12-02 | 2010-06-10 | Dong Wha Pharm. Co., Ltd. | The pharmaceutical composition or the functional foods for the treatment or prevention of obesity comprising the extract from myristica fragrans houttuyn |
| KR101062670B1 (ko) * | 2009-06-01 | 2011-09-06 | (주)아모레퍼시픽 | 2,5-비스-아릴-3,4-디메틸테트라하이드로퓨란 리그난을 유효성분으로 포함하는 에이엠피케이의 활성화에 의해 매개되는 비만 관련 질환의 예방 또는 치료용 조성물 |
| PE20121316A1 (es) | 2009-11-13 | 2012-10-05 | Sanofi Aventis Deutschland | Composicion farmaceutica que comprende un agonista de glp-1 y metionina |
| PT2554183T (pt) | 2009-11-13 | 2018-07-09 | Sanofi Aventis Deutschland | Composição farmacêutica que compreende um agonista de glp-1, uma insulina e metionina |
| EP2555745B1 (de) | 2010-04-08 | 2016-12-21 | Symrise AG | Verwendung von dihydrodehydrodiisoeugenol und zubereitungen mit dihydrodehydrodiisoeugenol |
| US20140148384A1 (en) | 2010-08-30 | 2014-05-29 | Sanofi-Aventis Deutschland Gmbh | Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2 |
| US20120277147A1 (en) * | 2011-03-29 | 2012-11-01 | Sanofi-Aventis Deutschland Gmbh | Prevention of hypoglycaemia in diabetes mellitus type 2 patients |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| CN108079281A (zh) | 2011-08-29 | 2018-05-29 | 赛诺菲-安万特德国有限公司 | 用于2型糖尿病患者中的血糖控制的药物组合 |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| TWI758239B (zh) | 2014-12-12 | 2022-03-21 | 德商賽諾菲阿凡提斯德意志有限公司 | 甘精胰島素/利司那肽固定比率配製劑 |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第２型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第２型糖尿病病患之治療 |
| CN105153107B (zh) * | 2015-08-21 | 2017-06-06 | 河南大学 | 一种促凝血肉豆蔻外壳有效成分及其提取分离方法、应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA200103250B (en) * | 2000-01-20 | 2001-10-25 | Irene Amiras | The treatment of immunomodulatory related and other diseases or conditions. |
| JP2007504285A (ja) * | 2003-01-17 | 2007-03-01 | メルク エンド カムパニー インコーポレーテッド | Ｎ−シクロヘキシルアミノカルボニルベンゼンスルホンアミド誘導体 |
| KR100909918B1 (ko) * | 2003-05-20 | 2009-07-29 | 노파르티스 아게 | 과산화소체 증식체-활성화 수용체의 리간드로서의 ｎ-아실질소 헤테로환 |
| US6987118B2 (en) * | 2003-05-21 | 2006-01-17 | Pfizer Inc. | Tetrahydroisoquinoline derivatives as PPAR-alpha activators |
| US20050004179A1 (en) * | 2003-05-22 | 2005-01-06 | Pedersen Ward A. | Methods and materials for treating, detecting, and reducing the risk of developing Alzheimer's Disease |
| BRPI0414536A (pt) * | 2003-09-17 | 2006-11-07 | Novartis Ag | compostos orgánicos |
| BRPI0416283A (pt) * | 2003-11-05 | 2007-01-23 | Hoffmann La Roche | compostos, processo para a fabricação de compostos, composição farmacêutica, método para o tratamento e/ou prevenção de doenças que são moduladas por agonistas de ppar(delta) e/ou ppar(alfa) e uso destes compostos |
| US20080114058A1 (en) * | 2005-01-07 | 2008-05-15 | Jae-Kwan Hwang | Use Of Lignan Compounds For Treating Or Preventing Inflammatory Disease |
| KR100679306B1 (ko) * | 2005-03-31 | 2007-02-06 | 아미코젠주식회사 | 리그난계 화합물을 함유하는 뇌신경질환의 치료 또는예방용 약학적 조성물 |
| WO2007056124A2 (en) * | 2005-11-04 | 2007-05-18 | Hydra Biosciences, Inc. | Compounds for modulating trpv3 function |
-
2006
- 2006-06-27 JP JP2008518046A patent/JP5416969B2/ja not_active Expired - Fee Related
- 2006-06-27 WO PCT/KR2006/002493 patent/WO2007001150A2/en not_active Ceased
- 2006-06-27 AT AT06769069T patent/ATE539743T1/de active
- 2006-06-27 EP EP06769069A patent/EP1948161B1/de active Active
- 2006-06-27 US US11/922,509 patent/US7902254B1/en active Active
- 2006-06-27 CN CN2006800230079A patent/CN102036662B/zh not_active Expired - Fee Related
- 2006-06-27 ES ES06769069T patent/ES2380556T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2380556T3 (es) | 2012-05-16 |
| JP2008543931A (ja) | 2008-12-04 |
| CN102036662B (zh) | 2013-02-27 |
| CN102036662A (zh) | 2011-04-27 |
| US20110071221A1 (en) | 2011-03-24 |
| WO2007001150A2 (en) | 2007-01-04 |
| EP1948161A4 (de) | 2010-04-21 |
| EP1948161B1 (de) | 2012-01-04 |
| EP1948161A2 (de) | 2008-07-30 |
| US7902254B1 (en) | 2011-03-08 |
| JP5416969B2 (ja) | 2014-02-12 |
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