ATE539749T1 - Dextromethorphan für die behandlung von akne - Google Patents

Dextromethorphan für die behandlung von akne

Info

Publication number: ATE539749T1
Authority: AT; Austria
Prior art keywords: treatment; patient; administering; compound; effective amount
Prior art date: 2006-02-24

Application number

AT06751392T

Other languages

English (en)

Inventor

Hua-Lin Wu

Guey-Yueh Shi

Chuan-Chi Chiang

Hui-Pin Su

Original Assignee

Blue Blood Biotech Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-02-24

Filing date

2006-04-26

Publication date

2012-01-15

2006-04-26 Application filed by Blue Blood Biotech Corp filed Critical Blue Blood Biotech Corp

2012-01-15 Application granted granted Critical

2012-01-15 Publication of ATE539749T1 publication Critical patent/ATE539749T1/de

Links

208000002874 Acne Vulgaris Diseases 0.000 title 1
206010000496 acne Diseases 0.000 title 1
MKXZASYAUGDDCJ-NJAFHUGGSA-N dextromethorphan Chemical compound C([C@@H]12)CCC[C@]11CCN(C)[C@H]2CC2=CC=C(OC)C=C21 MKXZASYAUGDDCJ-NJAFHUGGSA-N 0.000 title 1
238000000034 method Methods 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 abstract 1
208000035143 Bacterial infection Diseases 0.000 abstract 1
102100021943 C-C motif chemokine 2 Human genes 0.000 abstract 1
101710155857 C-C motif chemokine 2 Proteins 0.000 abstract 1
206010061218 Inflammation Diseases 0.000 abstract 1
108090001005 Interleukin-6 Proteins 0.000 abstract 1
102000004889 Interleukin-6 Human genes 0.000 abstract 1
MKXZASYAUGDDCJ-SZMVWBNQSA-N LSM-2525 Chemical compound C1CCC[C@H]2[C@@]3([H])N(C)CC[C@]21C1=CC(OC)=CC=C1C3 MKXZASYAUGDDCJ-SZMVWBNQSA-N 0.000 abstract 1
229940123857 NADPH oxidase inhibitor Drugs 0.000 abstract 1
108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 1
102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
208000022362 bacterial infectious disease Diseases 0.000 abstract 1
239000003899 bactericide agent Substances 0.000 abstract 1
230000003385 bacteriostatic effect Effects 0.000 abstract 1
229960001985 dextromethorphan Drugs 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000004054 inflammatory process Effects 0.000 abstract 1
210000002540 macrophage Anatomy 0.000 abstract 1
UZHSEJADLWPNLE-GRGSLBFTSA-N naloxone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(O)C2=C5[C@@]13CCN4CC=C UZHSEJADLWPNLE-GRGSLBFTSA-N 0.000 abstract 1
229960004127 naloxone Drugs 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000028327 secretion Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Emergency Medicine (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT06751392T 2006-02-24 2006-04-26 Dextromethorphan für die behandlung von akne ATE539749T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US11/361,589 US7939567B2 (en)	2006-02-24	2006-02-24	Dextromethorphan-based method for treating acne
PCT/US2006/015661 WO2007097765A1 (en)	2006-02-24	2006-04-26	Methods and compositions for bactericide, bacteriostatic and anti-inflammation

Publications (1)

Publication Number	Publication Date
ATE539749T1 true ATE539749T1 (de)	2012-01-15

Family

ID=38437685

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06751392T ATE539749T1 (de)	2006-02-24	2006-04-26	Dextromethorphan für die behandlung von akne

Country Status (13)

Country	Link
US (1)	US7939567B2 (de)
EP (1)	EP1986620B1 (de)
JP (1)	JP5347195B2 (de)
KR (1)	KR101279196B1 (de)
CN (1)	CN101023947B (de)
AT (1)	ATE539749T1 (de)
AU (1)	AU2006338583B8 (de)
BR (1)	BRPI0621210A2 (de)
CA (1)	CA2643277A1 (de)
IL (1)	IL193628A0 (de)
TW (1)	TWI365743B (de)
WO (1)	WO2007097765A1 (de)
ZA (1)	ZA200806703B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8461102B2 (en) *	2010-03-02	2013-06-11	George E. Royster, JR.	Methods and compositions for treating and preventing symptoms of hormonal variations
BR112012028153A2 (pt) *	2010-05-03	2018-08-07	Tsh Biopharm Corporation Ltd	composição farmacêutica e método para o tratamento de hipertensão
AU2011259204B2 (en) *	2010-05-27	2015-05-21	Kenichiro Hasumi	Antigen peptide and use thereof
CN103826635A (zh)	2011-07-28	2014-05-28	伊恩.S.扎冈	治疗上皮创伤的方法和组合物
CN105101964A (zh) *	2013-01-21	2015-11-25	保罗·比利亚尔迪	选择性δ-阿片受体拮抗剂和特异性感觉器配体的用途
AU2015252949B2 (en) *	2014-05-01	2020-12-10	Anterios, Inc.	Methods to treat, prevent, and improve skin conditions
MX2019005833A (es)	2016-11-21	2019-10-30	Eirion Therapeutics Inc	Administracion transdermica de agentes grandes.
CN106801037B (zh) *	2017-01-06	2021-01-19	中国人民解放军南京军区福州总医院	体外痤疮炎症模型的建立方法及其应用
WO2020123194A1 (en) *	2018-12-11	2020-06-18	Kristoffer Hellstrand	Methods of reducing post-surgical metastasis
CN114409673B (zh) *	2022-01-04	2023-08-08	广东克冠达医药科技有限公司	一种吗啡喃类化合物及其制备方法与应用
CN120957729A (zh) *	2023-03-21	2025-11-14	R·萨曼特	新型磷酸酯化合物及其制备方法
CN118178506B (zh) *	2024-03-18	2025-09-12	山东中医药大学附属医院	升麻提取物、灵芝多糖和nadph联合使用在制备治疗重症脓毒症药物中的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2676177A (en)	1949-11-09	1954-04-20	Hoffmann La Roche	Process for the preparation of optically active 3-methoxy-n-methyl morphinans and salts thereof
CA1214393A (en) *	1984-06-26	1986-11-25	Eric L. Nelson	Composition useful in the treatment of diarrhea
EP0506477B1 (de) *	1991-03-28	1999-06-23	Merck & Co. Inc.	Untereinheit-C des vaskulären endothelialen Zellwachstumsfaktors
US5206248A (en)	1992-03-27	1993-04-27	Smith Richard A	Method for reducing emotional lability
US5366980A (en)	1991-06-17	1994-11-22	Smith Richard A	Use of dextromethorphan and an oxidase inhibitor to treat dermatitis
US5260066A (en)	1992-01-16	1993-11-09	Srchem Incorporated	Cryogel bandage containing therapeutic agent
US5834480A (en)	1997-06-13	1998-11-10	Elkhoury; George F.	Topical application of opioids for treatment of acne and sebaceous gland disorders
US5994330A (en) *	1998-11-09	1999-11-30	El Khoury; Georges F.	Topical application of muscarinic agents such as neostigmine for treatment of acne and other inflammatory conditions
HU229705B1 (en) *	2000-02-08	2014-05-28	Euro Celtique Sa	Tamper-resistant oral opioid agonist formulations
CN1200709C (zh) *	2003-01-23	2005-05-11	张以成	氢溴酸右美沙芬滴丸及其制备方法

2006
- 2006-02-24 US US11/361,589 patent/US7939567B2/en not_active Expired - Lifetime
- 2006-03-07 TW TW095107622A patent/TWI365743B/zh active
- 2006-04-26 BR BRPI0621210-7A patent/BRPI0621210A2/pt not_active IP Right Cessation
- 2006-04-26 EP EP06751392A patent/EP1986620B1/de not_active Expired - Lifetime
- 2006-04-26 CA CA002643277A patent/CA2643277A1/en not_active Abandoned
- 2006-04-26 JP JP2008556294A patent/JP5347195B2/ja not_active Expired - Lifetime
- 2006-04-26 KR KR1020087020105A patent/KR101279196B1/ko not_active Expired - Lifetime
- 2006-04-26 AT AT06751392T patent/ATE539749T1/de active
- 2006-04-26 WO PCT/US2006/015661 patent/WO2007097765A1/en not_active Ceased
- 2006-04-26 AU AU2006338583A patent/AU2006338583B8/en not_active Expired
- 2006-08-15 CN CN2006101121600A patent/CN101023947B/zh active Active
2008
- 2008-08-01 ZA ZA200806703A patent/ZA200806703B/xx unknown
- 2008-08-21 IL IL193628A patent/IL193628A0/en unknown

Also Published As

Publication number	Publication date
EP1986620A4 (de)	2009-11-25
KR20080106183A (ko)	2008-12-04
IL193628A0 (en)	2009-08-03
CA2643277A1 (en)	2007-08-30
ZA200806703B (en)	2009-09-30
EP1986620A1 (de)	2008-11-05
BRPI0621210A2 (pt)	2011-12-06
TWI365743B (en)	2012-06-11
AU2006338583A1 (en)	2007-08-30
TW200731972A (en)	2007-09-01
KR101279196B1 (ko)	2013-06-26
US7939567B2 (en)	2011-05-10
EP1986620B1 (de)	2012-01-04
AU2006338583B8 (en)	2012-01-12
JP5347195B2 (ja)	2013-11-20
CN101023947B (zh)	2012-10-31
JP2009527553A (ja)	2009-07-30
US20070203164A1 (en)	2007-08-30
CN101023947A (zh)	2007-08-29
AU2006338583B2 (en)	2011-12-22
WO2007097765A1 (en)	2007-08-30

Publication	Publication Date	Title
IL193628A0 (en)	2009-08-03	Methods and compositions for bactericide, bacteriostatic and anti-inflammation
RU2010144637A (ru)	2012-05-27	Замещенные гамма-лактамы в качестве терапевтических агентов
ATE416177T1 (de)	2008-12-15	Hetaryloxy-substituierte phenylaminopyrimidine als rho-kinasehemmer
TW200640864A (en)	2006-12-01	Pyridyl non-aromatic nitrogenated heterocyclic-1-carboxylate ester derivative
IL192100A0 (en)	2009-08-03	Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
EA200800538A1 (ru)	2008-06-30	Терапевтические соединения
SG159388A1 (en)	2010-03-30	Antibacterial agents
NO20074999L (no)	2007-12-03	Metode og preparat for behandling av perifere vaskulaere sykdommer
MA33076B1 (fr)	2012-03-01	Utilisation d'un inhibiteur de la gamma-secretase pour le traitement du cancer
EP2639229A3 (de)	2013-12-25	Thiazolderivate und deren Verwendung als VAP-1-Hemmer
MX2011009709A (es)	2011-12-06	Compuestos para el tratamiento de la inflamacion y del dolor.
WO2003073981A3 (en)	2003-11-27	Novel of cytokine inhibitors
MY147864A (en)	2013-01-31	Beta-2 adrenoceptor agonists for treating connective tissue diseases of the skin
MX362830B (es)	2019-02-14	Agente terapeutico o profilactico para enfermedades del tracto biliar.
MX2009011818A (es)	2009-11-13	Formulaciones de aminoacido n-halogenado con compuestos anti-inflamatorios.
CL2021003303A1 (es)	2022-08-19	Tratamiento para sinucleinopatías.
MY148565A (en)	2013-04-30	Agent for therapy and/or improvement of disseminated intravascular coagulation
NO20044568L (no)	2004-12-22	Fremgangsmate for inhibering av atrofi eller for behandling eller forhindring av atrofi-relaterte symptomer i kvinner
WO2008088987B1 (en)	2008-09-18	Treatment of pain with naloxone
NZ582328A (en)	2012-08-31	Pharmaceutical combination of opioid and prostaglandin compound
WO2001055108A3 (en)	2001-12-20	Use of spl a2 inhibitors for the treatment of inflammation
SI1553938T1 (sl)	2007-06-30	Uporaba epotilonskih derivatov za zdravljenje hiperparatiroidizma
ATE442848T1 (de)	2009-10-15	Isoxazolsäure-derivat zur linderung neuropathischer schmerzen
RU2014126635A (ru)	2016-02-10	Лечение себореи
JO2586B1 (en)	2011-02-27	Use of different sulfamide derivatives combined with benzo ring for pain management