ATE540914T1 - Reinigung von fluoromethyl-1,1,1,3,3,3- hexafluoroisopropyl-ether (sevofluran) - Google Patents

Reinigung von fluoromethyl-1,1,1,3,3,3- hexafluoroisopropyl-ether (sevofluran)

Info

Publication number: ATE540914T1
Authority: AT; Austria
Prior art keywords: sevoflurane; fluoromethyl; purification; multiphase mixture; hexafluoroisopropyl ether
Prior art date: 2005-08-04

Application number

AT06800644T

Other languages

English (en)

Inventor

Barry Jones

Joel Swinson

Original Assignee

Halocarbon Prod Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-08-04

Filing date

2006-08-02

Publication date

2012-01-15

2006-08-02 Application filed by Halocarbon Prod Corp filed Critical Halocarbon Prod Corp

2012-01-15 Application granted granted Critical

2012-01-15 Publication of ATE540914T1 publication Critical patent/ATE540914T1/de

Links

DFEYYRMXOJXZRJ-UHFFFAOYSA-N sevoflurane Chemical compound FCOC(C(F)(F)F)C(F)(F)F DFEYYRMXOJXZRJ-UHFFFAOYSA-N 0.000 title abstract 5
229960002078 sevoflurane Drugs 0.000 title abstract 5
OOKYWAXNZYBZER-UHFFFAOYSA-N 3-amino-3-(4-ethoxy-3-methoxyphenyl)propanoic acid Chemical compound CCOC1=CC=C(C(N)CC(O)=O)C=C1OC OOKYWAXNZYBZER-UHFFFAOYSA-N 0.000 title 1
238000000746 purification Methods 0.000 title 1
239000000203 mixture Substances 0.000 abstract 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/34—Separation; Purification; Stabilisation; Use of additives
- C07C41/40—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation
- C07C41/42—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation by distillation
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
- B01D3/34—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping with one or more auxiliary substances
- B01D3/36—Azeotropic distillation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/34—Separation; Purification; Stabilisation; Use of additives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/04—Saturated ethers
- C07C43/12—Saturated ethers containing halogen
- C07C43/123—Saturated ethers containing halogen both carbon chains are substituted by halogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Crystallography & Structural Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT06800644T 2005-08-04 2006-08-02 Reinigung von fluoromethyl-1,1,1,3,3,3- hexafluoroisopropyl-ether (sevofluran) ATE540914T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US70540805P	2005-08-04	2005-08-04
PCT/US2006/030046 WO2007019161A2 (en)	2005-08-04	2006-08-02	Purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane)

Publications (1)

Publication Number	Publication Date
ATE540914T1 true ATE540914T1 (de)	2012-01-15

Family

ID=37727866

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06800644T ATE540914T1 (de)	2005-08-04	2006-08-02	Reinigung von fluoromethyl-1,1,1,3,3,3- hexafluoroisopropyl-ether (sevofluran)

Country Status (14)

Country	Link
US (1)	US7750192B2 (de)
EP (1)	EP1910258B1 (de)
JP (1)	JP5069236B2 (de)
KR (1)	KR100997836B1 (de)
CN (1)	CN101263102B (de)
AT (1)	ATE540914T1 (de)
BR (1)	BRPI0614298A2 (de)
CA (1)	CA2618345C (de)
DK (1)	DK1910258T3 (de)
ES (1)	ES2381573T3 (de)
IL (1)	IL189243A (de)
MX (1)	MX2008001654A (de)
WO (1)	WO2007019161A2 (de)
ZA (1)	ZA200801327B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7732647B2 (en)	2007-12-27	2010-06-08	Halocarbon Products Corporation	Process for the purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane)
RU2486170C1 (ru) *	2009-06-15	2013-06-27	Дайкин Индастриз, Лтд.	Способ получения фторсодержащего простого эфира высокой чистоты
IN2012DN02769A (de) *	2009-09-01	2015-09-18	Blue Zone Technologies Ltd
EP2889355B1 (de) *	2013-12-26	2017-04-19	Central Glass Company, Limited	Azeotrope mischungsartige zusammensetzung, wärmeübertragungszusammensetzung, reiniger, hochtemperaturwärmepumpenvorrichtung und wärmeübertragungsverfahren
CN105566074A (zh) *	2014-10-08	2016-05-11	浙江化工院科技有限公司	一种纯化六氟异丙基甲醚的方法
CN105523903B (zh) *	2016-01-30	2017-07-18	华东医药（西安）博华制药有限公司	一种七氟烷的纯化方法
JP6299905B1 (ja)	2017-02-06	2018-03-28	セントラル硝子株式会社	セボフルランの製造方法
CN107698430B (zh) *	2017-11-01	2021-01-08	华东医药（西安）博华制药有限公司	一种七氟烷反应液的后处理方法
CN114560758B (zh) *	2022-02-22	2023-08-18	中船(邯郸)派瑞特种气体股份有限公司	一种电子级九氟丁基甲醚的纯化方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4250331A (en)	1979-10-09	1981-02-10	E. I. Du Pont De Nemours And Company	Removal of organic acids from dilute aqueous solutions of salts of organic acids by supercritical fluids
US4250334A (en)	1979-12-26	1981-02-10	Baxter Travenol Laboratories, Inc.	Method of synthesizing fluoromethylhexafluoroisopropyl ether
JP2865554B2 (ja) *	1994-04-08	1999-03-08	セントラル硝子株式会社	フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルのガスクロマトグラフ分析
US5969193A (en) *	1997-08-18	1999-10-19	Medeva Pharmaceuticals Pa, Inc.	Method for the preparation of sevoflurane
US6469219B1 (en) *	2000-03-16	2002-10-22	Halocarbon Products Corporation	Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether

2006
- 2006-08-02 ES ES06800644T patent/ES2381573T3/es active Active
- 2006-08-02 DK DK06800644.4T patent/DK1910258T3/da active
- 2006-08-02 AT AT06800644T patent/ATE540914T1/de active
- 2006-08-02 CA CA2618345A patent/CA2618345C/en active Active
- 2006-08-02 KR KR1020087004828A patent/KR100997836B1/ko not_active Expired - Fee Related
- 2006-08-02 WO PCT/US2006/030046 patent/WO2007019161A2/en not_active Ceased
- 2006-08-02 EP EP06800644A patent/EP1910258B1/de not_active Not-in-force
- 2006-08-02 US US11/997,435 patent/US7750192B2/en not_active Expired - Fee Related
- 2006-08-02 CN CN2006800335846A patent/CN101263102B/zh not_active Expired - Fee Related
- 2006-08-02 JP JP2008525141A patent/JP5069236B2/ja not_active Expired - Fee Related
- 2006-08-02 MX MX2008001654A patent/MX2008001654A/es active IP Right Grant
- 2006-08-02 BR BRPI0614298-2A patent/BRPI0614298A2/pt not_active IP Right Cessation
2008
- 2008-02-04 IL IL189243A patent/IL189243A/en not_active IP Right Cessation
- 2008-02-07 ZA ZA200801327A patent/ZA200801327B/xx unknown

Also Published As

Publication number	Publication date
IL189243A (en)	2011-10-31
MX2008001654A (es)	2008-04-07
IL189243A0 (en)	2008-08-07
US20080214875A1 (en)	2008-09-04
EP1910258A4 (de)	2010-12-08
CN101263102A (zh)	2008-09-10
US7750192B2 (en)	2010-07-06
EP1910258A2 (de)	2008-04-16
JP2009503095A (ja)	2009-01-29
CN101263102B (zh)	2011-08-17
ZA200801327B (en)	2009-01-28
ES2381573T3 (es)	2012-05-29
JP5069236B2 (ja)	2012-11-07
KR20080034489A (ko)	2008-04-21
WO2007019161A2 (en)	2007-02-15
WO2007019161A3 (en)	2007-07-19
DK1910258T3 (da)	2012-05-07
BRPI0614298A2 (pt)	2011-03-22
EP1910258B1 (de)	2012-01-11
CA2618345A1 (en)	2007-02-15
CA2618345C (en)	2012-03-06
KR100997836B1 (ko)	2010-12-01

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