ATE540946T1 - Dioxaspiroketalderivate, verfahren zu ihrer herstellung und anwendungen davon - Google Patents
Dioxaspiroketalderivate, verfahren zu ihrer herstellung und anwendungen davonInfo
- Publication number
- ATE540946T1 ATE540946T1 AT07736845T AT07736845T ATE540946T1 AT E540946 T1 ATE540946 T1 AT E540946T1 AT 07736845 T AT07736845 T AT 07736845T AT 07736845 T AT07736845 T AT 07736845T AT E540946 T1 ATE540946 T1 AT E540946T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- dioxaspiroketal
- derivatives
- applications
- production
- Prior art date
Links
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 4
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000257A ITRM20060257A1 (it) | 2006-05-15 | 2006-05-15 | Derivati diossaspirochetalici procedimento di preparazione e usi relativi |
| PCT/IT2007/000342 WO2007132496A1 (en) | 2006-05-15 | 2007-05-10 | Dioxaspiroketal derivatives, process for their preparation and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE540946T1 true ATE540946T1 (de) | 2012-01-15 |
Family
ID=38474426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07736845T ATE540946T1 (de) | 2006-05-15 | 2007-05-10 | Dioxaspiroketalderivate, verfahren zu ihrer herstellung und anwendungen davon |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8916717B2 (de) |
| EP (1) | EP2027115B1 (de) |
| AT (1) | ATE540946T1 (de) |
| CA (1) | CA2652705A1 (de) |
| IT (1) | ITRM20060257A1 (de) |
| WO (1) | WO2007132496A1 (de) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH107557A (ja) | 1996-06-17 | 1998-01-13 | Banyu Pharmaceut Co Ltd | 抗腫瘍性物質スピロラキシン |
| AU4845499A (en) * | 1998-06-29 | 2000-01-17 | Parker Hughes Institute | Synthetic spiroketal pyranes as potent anti-cancer agents |
-
2006
- 2006-05-15 IT IT000257A patent/ITRM20060257A1/it unknown
-
2007
- 2007-05-10 EP EP07736845A patent/EP2027115B1/de not_active Not-in-force
- 2007-05-10 AT AT07736845T patent/ATE540946T1/de active
- 2007-05-10 US US12/227,228 patent/US8916717B2/en not_active Expired - Fee Related
- 2007-05-10 WO PCT/IT2007/000342 patent/WO2007132496A1/en not_active Ceased
- 2007-05-10 CA CA002652705A patent/CA2652705A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US8916717B2 (en) | 2014-12-23 |
| ITRM20060257A1 (it) | 2007-11-16 |
| EP2027115B1 (de) | 2012-01-11 |
| EP2027115A1 (de) | 2009-02-25 |
| WO2007132496A1 (en) | 2007-11-22 |
| US20100227919A1 (en) | 2010-09-09 |
| CA2652705A1 (en) | 2007-11-22 |
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