ATE540961T1 - Furanosederivate fuer die herstellung von atorvastatin - Google Patents
Furanosederivate fuer die herstellung von atorvastatinInfo
- Publication number
- ATE540961T1 ATE540961T1 AT08762340T AT08762340T ATE540961T1 AT E540961 T1 ATE540961 T1 AT E540961T1 AT 08762340 T AT08762340 T AT 08762340T AT 08762340 T AT08762340 T AT 08762340T AT E540961 T1 ATE540961 T1 AT E540961T1
- Authority
- AT
- Austria
- Prior art keywords
- atorvastatin
- production
- furanose
- derivatives
- furanose derivatives
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- XUKUURHRXDUEBC-KAYWLYCHSA-N Atorvastatin Chemical compound C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-KAYWLYCHSA-N 0.000 title abstract 2
- XUKUURHRXDUEBC-UHFFFAOYSA-N Atorvastatin Natural products C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CCC(O)CC(O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-UHFFFAOYSA-N 0.000 title abstract 2
- 229960005370 atorvastatin Drugs 0.000 title abstract 2
- 150000002242 furanose derivatives Chemical class 0.000 title abstract 2
- 150000002243 furanoses Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94335707P | 2007-06-12 | 2007-06-12 | |
| GBGB0711250.1A GB0711250D0 (en) | 2007-06-12 | 2007-06-12 | Furanose derivatives |
| PCT/GB2008/002008 WO2008152386A1 (en) | 2007-06-12 | 2008-06-12 | Furanose derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE540961T1 true ATE540961T1 (de) | 2012-01-15 |
Family
ID=38319159
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08762340T ATE540961T1 (de) | 2007-06-12 | 2008-06-12 | Furanosederivate fuer die herstellung von atorvastatin |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8115010B2 (de) |
| EP (2) | EP2380895A1 (de) |
| JP (1) | JP2010529181A (de) |
| AT (1) | ATE540961T1 (de) |
| BR (1) | BRPI0813111A2 (de) |
| GB (1) | GB0711250D0 (de) |
| RU (1) | RU2010105978A (de) |
| WO (1) | WO2008152386A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0711250D0 (en) * | 2007-06-12 | 2007-07-18 | Cbz Chemicals Ltd | Furanose derivatives |
| JP2015501818A (ja) * | 2011-12-16 | 2015-01-19 | アルフォラ リサーチ インコーポレイテッドＡｌｐｈｏｒａ Ｒｅｓｅａｒｃｈ Ｉｎｃ． | ３−（（２ｓ，５ｓ）−４−メチレン−５−（３−オキソプロピル）テトラヒドロフラン−２−イル）プロパノール誘導体およびそれらの有用な中間体を調製する方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5003080A (en) | 1988-02-22 | 1991-03-26 | Warner-Lambert Company | Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis |
| FI94339C (fi) | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
| US20040102511A1 (en) | 2002-11-21 | 2004-05-27 | Jitendra Sattigeri | Substituted pyrrole derivatives |
| CA2498978A1 (en) * | 2005-02-28 | 2006-08-28 | Apotex Pharmachem Inc. | An improved process for the preparation of atorvastatin and intermediates |
| GB0711250D0 (en) * | 2007-06-12 | 2007-07-18 | Cbz Chemicals Ltd | Furanose derivatives |
-
2007
- 2007-06-12 GB GBGB0711250.1A patent/GB0711250D0/en not_active Ceased
-
2008
- 2008-06-12 JP JP2010511718A patent/JP2010529181A/ja active Pending
- 2008-06-12 RU RU2010105978/04A patent/RU2010105978A/ru unknown
- 2008-06-12 BR BRPI0813111-2A2A patent/BRPI0813111A2/pt not_active IP Right Cessation
- 2008-06-12 US US12/664,455 patent/US8115010B2/en not_active Expired - Fee Related
- 2008-06-12 EP EP11172240A patent/EP2380895A1/de not_active Withdrawn
- 2008-06-12 EP EP08762340A patent/EP2170916B1/de not_active Not-in-force
- 2008-06-12 AT AT08762340T patent/ATE540961T1/de active
- 2008-06-12 WO PCT/GB2008/002008 patent/WO2008152386A1/en not_active Ceased
-
2011
- 2011-09-23 US US13/243,363 patent/US8278468B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008152386A1 (en) | 2008-12-18 |
| EP2170916A1 (de) | 2010-04-07 |
| US20100179331A1 (en) | 2010-07-15 |
| GB0711250D0 (en) | 2007-07-18 |
| RU2010105978A (ru) | 2011-08-27 |
| US8115010B2 (en) | 2012-02-14 |
| BRPI0813111A2 (pt) | 2014-12-23 |
| JP2010529181A (ja) | 2010-08-26 |
| US8278468B2 (en) | 2012-10-02 |
| EP2170916B1 (de) | 2012-01-11 |
| US20120016135A1 (en) | 2012-01-19 |
| EP2380895A1 (de) | 2011-10-26 |
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