ATE541015T1 - Redox- und fotoinitiatorensysteme zur grundierung für eine verbesserte haftung von gelen an substraten - Google Patents

Redox- und fotoinitiatorensysteme zur grundierung für eine verbesserte haftung von gelen an substraten

Info

Publication number
ATE541015T1
ATE541015T1 AT07075463T AT07075463T ATE541015T1 AT E541015 T1 ATE541015 T1 AT E541015T1 AT 07075463 T AT07075463 T AT 07075463T AT 07075463 T AT07075463 T AT 07075463T AT E541015 T1 ATE541015 T1 AT E541015T1
Authority
AT
Austria
Prior art keywords
tissue
barrier
gel
priming
methods
Prior art date
Application number
AT07075463T
Other languages
English (en)
Inventor
Amarpreet S Sawhney
David A Melanson
Chandrashekar P Pathak
Jeffrey A Hubbell
Luis Z Avila
Mark T Kieras
Stephen D Goodrich
Shikha P Barman
Arthur J Coury
Ronald S Rudowsky
Douglas J K Weaver
Marc A Levine
John C Spiridigliozzi
Thomas S Bromander
Dean M Pichon
George Selecman
David J Nedder
Bradley C Poff
Donald L Elbert
Original Assignee
Genzyme Corp
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/472,745 external-priority patent/US5749968A/en
Application filed by Genzyme Corp, Univ Texas filed Critical Genzyme Corp
Application granted granted Critical
Publication of ATE541015T1 publication Critical patent/ATE541015T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0031—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0042—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/46—Polymerisation initiated by wave energy or particle radiation
    • C08F2/48—Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
    • C08F265/04—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F271/00—Macromolecular compounds obtained by polymerising monomers on to polymers of nitrogen-containing monomers as defined in group C08F26/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F289/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds not provided for in groups C08F251/00 - C08F287/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C08F290/062—Polyethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/08—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated side groups
    • C08F290/14—Polymers provided for in subclass C08G
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D4/00—Coating compositions, e.g. paints, varnishes or lacquers, based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond ; Coating compositions, based on monomers of macromolecular compounds of groups C09D183/00 - C09D183/16
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J151/00—Adhesives based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Adhesives based on derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/00491—Surgical glue applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B17/085—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound with adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/00491—Surgical glue applicators
    • A61B2017/00495—Surgical glue applicators for two-component glue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2666/00—Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
    • C08L2666/02—Organic macromolecular compounds, natural resins, waxes or and bituminous materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S602/00—Surgery: splint, brace, or bandage
    • Y10S602/90—Method of making bandage structure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S602/00—Surgery: splint, brace, or bandage
    • Y10S602/904—Film-forming bandage material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
AT07075463T 1995-03-23 1996-03-22 Redox- und fotoinitiatorensysteme zur grundierung für eine verbesserte haftung von gelen an substraten ATE541015T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/410,037 US5800373A (en) 1995-03-23 1995-03-23 Initiator priming for improved adherence of gels to substrates
US08/478,104 US5844016A (en) 1995-03-23 1995-06-07 Redox and photoinitiator priming for improved adherence of gels to substrates
US08/472,745 US5749968A (en) 1993-03-01 1995-06-07 Device for priming for improved adherence of gels to substrates

Publications (1)

Publication Number Publication Date
ATE541015T1 true ATE541015T1 (de) 2012-01-15

Family

ID=23622949

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07075463T ATE541015T1 (de) 1995-03-23 1996-03-22 Redox- und fotoinitiatorensysteme zur grundierung für eine verbesserte haftung von gelen an substraten

Country Status (3)

Country Link
US (2) US5800373A (de)
EP (1) EP1961791B1 (de)
AT (1) ATE541015T1 (de)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5900245A (en) * 1996-03-22 1999-05-04 Focal, Inc. Compliant tissue sealants
US6743248B2 (en) 1996-12-18 2004-06-01 Neomend, Inc. Pretreatment method for enhancing tissue adhesion
US20030191496A1 (en) 1997-03-12 2003-10-09 Neomend, Inc. Vascular sealing device with microwave antenna
US6371975B2 (en) 1998-11-06 2002-04-16 Neomend, Inc. Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers
EP1059882B1 (de) * 1998-03-06 2007-10-17 SPECTRX, Inc. Integrierte gewebeporations-, flüssigkeitsammel- und analysevorrichtung
US6350463B1 (en) 1998-05-23 2002-02-26 Andre Bieniarz Method of treatment for premature rupture of membranes in pregnancy (PROM)
US6994686B2 (en) 1998-08-26 2006-02-07 Neomend, Inc. Systems for applying cross-linked mechanical barriers
US6458147B1 (en) 1998-11-06 2002-10-01 Neomend, Inc. Compositions, systems, and methods for arresting or controlling bleeding or fluid leakage in body tissue
GB2341185A (en) * 1998-09-07 2000-03-08 Polybiomed Ltd Polymerizable material and adhesive sheet material therefrom; dressings, electrodes and transdermal patches
AU6151799A (en) 1998-09-17 2000-04-03 Focal, Inc. Self-cleaning fluid delivery device for medical applications
US6358269B1 (en) * 1998-11-02 2002-03-19 Ralph Aye Method of treating peripheral bronchopleural fistulas
US6830756B2 (en) * 1998-11-06 2004-12-14 Neomend, Inc. Systems, methods, and compositions for achieving closure of vascular puncture sites
US7279001B2 (en) * 1998-11-06 2007-10-09 Neomend, Inc. Systems, methods, and compositions for achieving closure of vascular puncture sites
US6899889B1 (en) 1998-11-06 2005-05-31 Neomend, Inc. Biocompatible material composition adaptable to diverse therapeutic indications
US7351249B2 (en) * 1998-11-06 2008-04-01 Neomend, Inc. Systems, methods, and compositions for achieving closure of suture sites
US6949114B2 (en) 1998-11-06 2005-09-27 Neomend, Inc. Systems, methods, and compositions for achieving closure of vascular puncture sites
US6310036B1 (en) 1999-01-09 2001-10-30 Last Chance Tissue Adhesives Corporation High strength, Bio-compatible tissue adhesive and methods for treating vigorously bleeding surfaces
US7018365B2 (en) 1999-05-21 2006-03-28 Micro Therapeutics, Inc. Threaded syringe with quick stop
US6375970B1 (en) 1999-07-07 2002-04-23 Andre Bieniarz Methods and materials for preterm birth prevention
US7008635B1 (en) 1999-09-10 2006-03-07 Genzyme Corporation Hydrogels for orthopedic repair
US8215314B2 (en) * 2000-02-11 2012-07-10 The General Hospital Corporation Photochemical tissue bonding
US7073510B2 (en) 2000-02-11 2006-07-11 The General Hospital Corporation Photochemical tissue bonding
EP2335634A1 (de) * 2000-02-11 2011-06-22 The General Hospital Corporation Photochemische Gewebeverbindung
EP1263803B1 (de) 2000-03-13 2007-09-19 BioCure, Inc. Embolische zusammensetzungen
US6652883B2 (en) * 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
US6800671B1 (en) * 2000-04-21 2004-10-05 Britesmile, Inc. Low peak exotherm curable compositions
US6607553B1 (en) 2000-11-17 2003-08-19 B. Braun Medical, Inc. Method for deploying a thermo-mechanically expandable stent
CA2433861A1 (en) 2000-12-27 2002-07-04 Genzyme Corporation Controlled release of anti-arrhythmic agents from a biodegradable polyethylene oxide hydrogel for local application to the heart
AU2002235694B2 (en) * 2001-02-28 2007-06-14 Covalon Technologies Inc. Method of making anti-microbial polymeric surfaces
US6730772B2 (en) 2001-06-22 2004-05-04 Venkatram P. Shastri Degradable polymers from derivatized ring-opened epoxides
US6746667B2 (en) 2001-07-05 2004-06-08 Closure Medical Corporation Adhesive treatment for tinea pedis
US6767552B2 (en) 2001-07-05 2004-07-27 Closure Medical Corporation Adhesive treatment for oral fungal infection
US6602496B2 (en) 2001-07-05 2003-08-05 Closure Medical Corporation Adhesive treatment for tinea corporis
US6585967B2 (en) 2001-07-05 2003-07-01 Closure Medical Corporation Adhesive treatment for tinea cruris
US6942875B2 (en) * 2001-07-05 2005-09-13 Closure Medical Corporation Adhesive treatment for skin yeast infections
US20030195610A1 (en) * 2002-04-04 2003-10-16 Herrmann Robert A. Processes for producing polymer coatings through surface polymerization
EP1539222A1 (de) * 2002-07-02 2005-06-15 The Regents Of The University Of California Behandlung von augenerkrankungen
US7217254B2 (en) 2002-09-20 2007-05-15 Genzyme Corporation Multi-pressure biocompatible agent delivery device and method
USD483475S1 (en) 2002-09-20 2003-12-09 Genzyme Corporation Fluent agent delivery device
US7862831B2 (en) * 2002-10-09 2011-01-04 Synthasome, Inc. Method and material for enhanced tissue-biomaterial integration
AU2003266947A1 (en) * 2002-10-02 2004-04-23 Coloplast A/S A hydrogel
US6800663B2 (en) * 2002-10-18 2004-10-05 Alkermes Controlled Therapeutics Inc. Ii, Crosslinked hydrogel copolymers
WO2005072764A2 (en) * 2004-01-16 2005-08-11 Novocell, Inc. Fibrin-bound angiogenic factors to stimulate vascularization of transplant site of encapsulated cells
US8002830B2 (en) 2004-02-06 2011-08-23 Georgia Tech Research Corporation Surface directed cellular attachment
AU2005212339B2 (en) 2004-02-06 2010-11-25 Georgia Tech Research Corporation Load bearing biocompatible device
AU2005237985B2 (en) 2004-04-20 2010-10-21 Genzyme Corporation Surgical mesh-like implant
US7727544B2 (en) * 2004-05-07 2010-06-01 The Regents Of The University Of California Treatment of myopia
US20050278025A1 (en) * 2004-06-10 2005-12-15 Salumedica Llc Meniscus prosthesis
ATE489058T1 (de) * 2004-06-29 2010-12-15 Inc Biocure Bandscheiben-nucleus-pulposus-implantat
EP1796693A2 (de) * 2004-08-26 2007-06-20 Chandrashekhar P. Pathak Implantierbare gewebezusammensetzungen und verfahren
EP1893162A2 (de) * 2005-06-15 2008-03-05 SurModics, Inc. Makromerzusammensetzung mit lichtaktiviertem initiator
WO2007080453A2 (en) 2005-11-09 2007-07-19 Klox Technologies Inc. Teeth whitening compositions and methods
US20070149641A1 (en) * 2005-12-28 2007-06-28 Goupil Dennis W Injectable bone cement
US20100285094A1 (en) * 2006-04-20 2010-11-11 University Of Utah Research Foundation Polymeric compositions and methods of making and using thereof
US8747870B2 (en) 2006-04-20 2014-06-10 University Of Utah Research Foundation Polymeric compositions and methods of making and using thereof
AU2007243483B2 (en) * 2006-04-24 2012-07-26 Incept, Llc Protein crosslinkers, crosslinking methods and applications thereof
US20100266989A1 (en) * 2006-11-09 2010-10-21 Klox Technologies Inc. Teeth whitening compositions and methods
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
US20090099579A1 (en) 2007-10-16 2009-04-16 Tyco Healthcare Group Lp Self-adherent implants and methods of preparation
WO2010027471A2 (en) 2008-09-04 2010-03-11 The General Hospital Corporation Hydrogels for vocal cord and soft tissue augmentation and repair
US8993068B2 (en) 2008-11-04 2015-03-31 The Trustees Of Columbia University In The City Of New York Heterobifunctional polymers and methods for layer-by-layer construction of multilayer films
PL2352488T3 (pl) 2008-11-07 2017-07-31 Klox Technologies Inc. Utleniająca, aktywowana światłem kompozycja do odmładzania skóry zawierająca kwas hialuronowy, glukozaminę lub alantoinę
EP2352796A1 (de) 2008-12-05 2011-08-10 Semprus Biociences Corporation Schichtförmige überzüge mit antifouling-, antimikrobiellen und antithrombogenen eigenschaften
WO2010065960A2 (en) * 2008-12-05 2010-06-10 Semprus Biosciences Corp. Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions
JP5890182B2 (ja) 2009-02-12 2016-03-22 インセプト エルエルシー ヒドロゲルプラグによる薬物送達
HUE035716T2 (en) 2009-07-17 2018-05-28 Klox Tech Inc Antibacterial oral composition
US9198568B2 (en) 2010-03-04 2015-12-01 The General Hospital Corporation Methods and systems of matching voice deficits with a tunable mucosal implant to restore and enhance individualized human sound and voice production
WO2011156596A2 (en) 2010-06-09 2011-12-15 Semprus Biosciences Corp. Articles having non-fouling surfaces and processes for preparing the same including pretreatment of substrates
CA2799786A1 (en) 2010-06-09 2011-12-15 Semprus Biosciences Corp. Non-fouling, anti-microbial, anti-thrombogenic graft compositions
AU2011264834B2 (en) 2010-06-09 2015-03-12 Semprus Biosciences Corp. Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions
US9232805B2 (en) 2010-06-29 2016-01-12 Biocure, Inc. In-situ forming hydrogel wound dressings containing antimicrobial agents
US8834418B2 (en) 2010-07-22 2014-09-16 Covidien Lp Molds for in situ forming materials
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
EP2679170A4 (de) * 2011-02-25 2015-06-24 Terumo Corp Applikator
US9006345B2 (en) 2011-03-25 2015-04-14 The Trustees Of Columbia University In The City Of New York Heterotrifunctional molecules and methods for the synthesis of dendrimeric materials
EP2757964B1 (de) 2011-05-26 2016-05-04 Cartiva, Inc. Konisches gelenkimplantat und zugehörige instrumente
DE102011112433A1 (de) 2011-09-06 2013-03-07 Dr. Kenndoff GmbH & Co. KG Verwendung einer semi-okklusiven flexiblen flächigen Wundauflage zur Behandlung von Wunden bei Tieren
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
US10849931B2 (en) 2011-09-30 2020-12-01 Depuy Synthes Products, Inc Compositions and methods for platelet enriched fibrin constructs
JP6199883B2 (ja) 2011-12-05 2017-09-20 インセプト・リミテッド・ライアビリティ・カンパニーＩｎｃｅｐｔ，Ｌｌｃ 医療用オルガノゲルプロセス及び組成物
WO2013090790A1 (en) 2011-12-14 2013-06-20 Semprus Biosciences Corp. Silicone hydrogel contact lens modified using lanthanide or transition metal oxidants
CA2858730C (en) 2011-12-14 2017-07-18 Semprus Biosciences Corp. Surface modified contact lenses
US9120119B2 (en) 2011-12-14 2015-09-01 Semprus Biosciences Corporation Redox processes for contact lens modification
CA2859195C (en) 2011-12-14 2016-09-27 Semprus Biosciences Corp. Imbibing process for contact lens surface modification
US9000063B2 (en) 2011-12-14 2015-04-07 Semprus Biosciences Corporation Multistep UV process to create surface modified contact lenses
US20130281913A1 (en) 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
US11116841B2 (en) 2012-04-20 2021-09-14 Klox Technologies Inc. Biophotonic compositions, kits and methods
WO2014015274A1 (en) 2012-07-20 2014-01-23 The General Hospital Corporation Methods for tissue passivation
US10549112B2 (en) 2012-07-20 2020-02-04 The General Hospital Corporation Apparatus for tissue irradiation and methods and kits utilizing the same
KR20150082189A (ko) 2012-09-14 2015-07-15 밸리언트 파마슈티컬즈 인터내셔널, 인코퍼레이션 치아미백용 조성물 및 치아미백 방법
US20140276354A1 (en) 2013-03-14 2014-09-18 Klox Technologies Inc. Biophotonic materials and uses thereof
HK1219890A1 (zh) 2013-07-03 2017-04-21 广东科洛克生物医药集团有限公司 治疗不癒合伤口的组合物和方法
CA3278502A1 (en) 2013-07-18 2025-10-31 The General Hospital Corporation Vessel treatment systems, methods, and kits
JP2017509433A (ja) 2014-04-01 2017-04-06 クロックス テクノロジーズ インコーポレイテッドＫｌｏｘ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． 組織充填剤組成物および使用方法
ES2856841T3 (es) 2014-10-31 2021-09-28 Klox Tech Inc Fibras y medios de tela fotoactivables
WO2016161026A1 (en) 2015-03-31 2016-10-06 Cartiva, Inc. Carpometacarpal (cmc) implants and methods
US9907663B2 (en) 2015-03-31 2018-03-06 Cartiva, Inc. Hydrogel implants with porous materials and methods
WO2016168363A1 (en) 2015-04-14 2016-10-20 Cartiva, Inc. Tooling for creating tapered opening in tissue and related methods
EP4279064A3 (de) 2015-05-12 2024-02-28 Incept, LLC Arzneimittelabgabe aus hydrogelen

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3223083A (en) * 1960-09-09 1965-12-14 President And Directors Of Geo Method for adhesively securing together skin and other soft tissue and bone
US3438374A (en) * 1966-02-28 1969-04-15 Us Health Education & Welfare Method of bonding tissue surfaces and controlling hemorrhaging thereof using a tissue adhesive and hemostatic composition
US3552986A (en) * 1967-11-24 1971-01-05 Sun Chemical Corp Printing and coating untreated polyolefins
CH593992A5 (de) * 1972-12-23 1977-12-30 Roehm Gmbh
US3948740A (en) * 1973-05-04 1976-04-06 Hercules Incorporated Polymerization of water soluble monomers with radiation and chemical initiator
US3939049A (en) * 1974-04-10 1976-02-17 The United States Of America As Represented By The United States Energy Research And Development Administration Process for radiation grafting hydrogels onto organic polymeric substrates
US4179304A (en) * 1978-04-03 1979-12-18 Polychrome Corporation Finger nail lacquer
US4222835A (en) * 1978-05-25 1980-09-16 Westinghouse Electric Corp. In depth curing of resins induced by UV radiation
US4303066A (en) * 1979-06-28 1981-12-01 National Patent Development Corporation Burn dressing
US4354487A (en) * 1980-05-12 1982-10-19 Johnson & Johnson Fiber/absorbent polymer composites and method of forming same
US4768523A (en) * 1981-04-29 1988-09-06 Lifecore Biomedical, Inc. Hydrogel adhesive
CA1194637A (en) * 1982-04-26 1985-10-01 Charles R. Morgan Uv and thermally curable, thermoplastic-containing compositions
US4511478A (en) * 1983-11-10 1985-04-16 Genetic Systems Corporation Polymerizable compounds and methods for preparing synthetic polymers that integrally contain polypeptides
US5177120A (en) * 1984-07-31 1993-01-05 Dentsply Research & Development Corp. Chain extended urethane diacrylate and dental impression formation
US4746685A (en) * 1984-08-31 1988-05-24 Nippon Oil And Fats Co., Ltd. Light curable dental composition
JPH0653647B2 (ja) * 1986-04-18 1994-07-20 而至歯科工業株式会社 歯科修復用組成物
US4741872A (en) * 1986-05-16 1988-05-03 The University Of Kentucky Research Foundation Preparation of biodegradable microspheres useful as carriers for macromolecules
US5160745A (en) * 1986-05-16 1992-11-03 The University Of Kentucky Research Foundation Biodegradable microspheres as a carrier for macromolecules
US5147698A (en) * 1986-09-30 1992-09-15 Minnesota Mining And Manufacturing Company Pressure sensitive adhesive film article having high moisture vapor transmission rate
US5009224A (en) * 1986-09-30 1991-04-23 Minnesota Mining And Manufacturing Company Method for attaching a pressure-sensitive film article having high moisture vapor transmission rate
US4846165A (en) * 1986-11-26 1989-07-11 Dentsply Research & Development Corp. Wound dressing membrane
US5389677B1 (en) * 1986-12-23 1997-07-15 Tristrata Inc Method of treating wrinkles using glycalic acid
IL82834A (en) * 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
NL8701548A (nl) * 1987-07-01 1989-02-01 Tno Polymeer netwerk, werkwijze voor het bereiden daarvan alsmede, de toepassing daarvan voor het bekleden en/of impregneren of voor het vervaardigen van ooglenzen, alsmede gevormd voortbrengsel, geheel of ten dele bestaande uit een dergelijk polymeer netwerk.
US4804691A (en) * 1987-08-28 1989-02-14 Richards Medical Company Method for making a biodegradable adhesive for soft living tissue
EP0310304B1 (de) * 1987-10-02 1993-11-18 Nippon Oil And Fats Company, Limited Durch sichtbares Licht härtbare Polyesterharzzusammensetzung
US4969912A (en) * 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
US5067961A (en) * 1988-02-18 1991-11-26 Autogenesis Technologies, Inc. Non-biodegradable two phase corneal implant and method for preparing same
US4985340A (en) * 1988-06-01 1991-01-15 Minnesota Mining And Manufacturing Company Energy curable compositions: two component curing agents
US5296627A (en) * 1988-06-20 1994-03-22 Ppg Industries, Inc. Ethylenically unsaturated poly(alkyleneoxy) surfactants
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
CA2002016A1 (en) * 1988-11-21 1990-05-21 Koji Miyake Manufacturing method, continuous manufacturing method, product and manufacturing apparatus of absorbent composite
US5137800A (en) * 1989-02-24 1992-08-11 Stereographics Limited Partnership Production of three dimensional bodies by photopolymerization
IL90193A (en) * 1989-05-04 1993-02-21 Biomedical Polymers Int Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same
US5226877A (en) * 1989-06-23 1993-07-13 Epstein Gordon H Method and apparatus for preparing fibrinogen adhesive from whole blood
US4997722A (en) * 1989-07-10 1991-03-05 Edward Adler Composition and method for improving adherence of copper foil to resinous substrates
EP0411925B1 (de) * 1989-08-02 1997-09-24 University Of North Carolina At Chapel Hill Verfahren zur Vernetzung von Kollagen und dadurch erzeugtes Produkt
US5116315A (en) * 1989-10-03 1992-05-26 Hemaedics, Inc. Biological syringe system
US5104375A (en) * 1989-10-16 1992-04-14 Johnson & Johnson Medical, Inc. Locking holder for a pair of syringes and method of use
US5104957A (en) * 1990-02-28 1992-04-14 Autogenesis Technologies, Inc. Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom
US5201764A (en) * 1990-02-28 1993-04-13 Autogenesis Technologies, Inc. Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom
HU213805B (en) * 1990-06-08 1997-10-28 Astra Ab Prefilled disposable device for introducing a pharmacologically active substance into a body cavity of a patient and method for manufacturing said device and mould apparatus for making said device
US5540677A (en) * 1990-06-15 1996-07-30 Rare Earth Medical, Inc. Endoscopic systems for photoreactive suturing of biological materials
US5209776A (en) * 1990-07-27 1993-05-11 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5512091A (en) * 1990-08-13 1996-04-30 Steiner; Carol A. Associative polymer hydrogels
US5403626A (en) * 1990-09-27 1995-04-04 Sam Yang Co., Limited Process for preparing hydrophilic polymer films and apparatus thereof
US5626863A (en) * 1992-02-28 1997-05-06 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5529914A (en) * 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
US5410016A (en) * 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
FR2668060B1 (fr) * 1990-10-17 1993-01-29 Fondation Nale Transfusion San Dispositif d'application d'un melange extemporane de plusieurs composants.
JP2928892B2 (ja) * 1990-11-27 1999-08-03 三洋化成工業株式会社 外科用接着剤
US5219895A (en) * 1991-01-29 1993-06-15 Autogenesis Technologies, Inc. Collagen-based adhesives and sealants and methods of preparation and use thereof
US5156613A (en) * 1991-02-13 1992-10-20 Interface Biomedical Laboratories Corp. Collagen welding rod material for use in tissue welding
US5308887A (en) * 1991-05-23 1994-05-03 Minnesota Mining & Manufacturing Company Pressure-sensitive adhesives
WO1993002639A1 (en) * 1991-08-06 1993-02-18 Autogenesis Technologies, Inc. Injectable collagen-based compositions for making intraocular lens
AU673160B2 (en) * 1992-02-28 1996-10-31 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5372585A (en) * 1992-04-09 1994-12-13 Tiefenbrun; Jonathan Instrument and associated method for applying biologically effective composition during laparoscopic operation
JPH05310808A (ja) * 1992-05-13 1993-11-22 Fuji Shirishia Kagaku Kk エポキシ基含有ポリマーで被覆された無機微粒子の製法
US5385606A (en) * 1992-07-06 1995-01-31 Kowanko; Nicholas Adhesive composition and method
US5516825A (en) * 1992-08-13 1996-05-14 Zeneca Limited Biodegradable polymer compositions
ES2130412T5 (es) * 1992-09-26 2005-03-16 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Aplicador de adhesivo destinado para tejidos.
US5278200A (en) * 1992-10-30 1994-01-11 Medtronic, Inc. Thromboresistant material and articles
CA2114290C (en) * 1993-01-27 2006-01-10 Nagabushanam Totakura Post-surgical anti-adhesion device
US5459177A (en) * 1993-03-09 1995-10-17 Sun Medical Co., Ltd. Adhesive for soft tissue and kit thereof
US5552452A (en) * 1993-03-15 1996-09-03 Arch Development Corp. Organic tissue glue for closure of wounds
US5502087A (en) * 1993-06-23 1996-03-26 Dentsply Research & Development Corp. Dental composition, prosthesis, and method for making dental prosthesis
FR2707878A1 (fr) * 1993-07-21 1995-01-27 Imedex Nouvelles compositions adhésives à usage chirurgical.
US5530038A (en) * 1993-08-02 1996-06-25 Sun Medical Co., Ltd. Primer composition and curable composition
TW272976B (de) * 1993-08-06 1996-03-21 Ciba Geigy Ag
DE4332310C1 (de) * 1993-09-23 1994-10-20 Heraeus Kulzer Gmbh Spritze zum dosierten Abgeben von viskosen Werkstoffen, insbesondere von dentalen Werkstoffen
RU2136319C1 (ru) * 1993-12-23 1999-09-10 Джонсон энд Джонсон Медикал, Инк. Биоабсорбируемое хирургическое гемостатическое средство и способ его получения (варианты)
US5525647A (en) * 1994-08-01 1996-06-11 American Dental Association Health Foundation Method and device for controllably affecting the reaction of dental adhesives
US5527864A (en) * 1995-08-08 1996-06-18 Suggs; Laura J. Poly(propylene fumarate-co-ethylene oxide)

Also Published As

Publication number Publication date
US5844016A (en) 1998-12-01
EP1961791A2 (de) 2008-08-27
EP1961791A3 (de) 2010-11-24
US5800373A (en) 1998-09-01
EP1961791B1 (de) 2012-01-11

Similar Documents

Publication Publication Date Title
ATE541015T1 (de) Redox- und fotoinitiatorensysteme zur grundierung für eine verbesserte haftung von gelen an substraten
ATE369402T1 (de) Redox und photoinitiatorsystem zur grundierung von verbesserter adhäsion von gelen zu substraten
US4987181A (en) Substrate with an antithromogenic active surface
DE3674505D1 (de) Verfahren zur kupplung von polymeren hergestellt durch anionischen polymerisation von dienmonomeren und/oder vinylaromatischen monomeren.
MX169277B (es) Peliculas termoplasticas para usarse en aplicaciones de alargamiento/adherencia
BE903099A (fr) Revetements durcissables au rayonnement pour structures pelliculaires.
KR100323043B1 (ko) 생물학적물질의캡슐화를위한고분자겔
ATE185586T1 (de) Zweikomponenten-kleb-/dichtstoff mit hoher anfangshaftfestigkeit
ES2136991T3 (es) Composicion fotocromatica curable.
DE59904996D1 (de) Verfahren zur herstellung von definierten schichten oder schichtsystemen
ATE279267T1 (de) Verfahren für die oberflächenbeschichtung von materialien
IT1206738B (it) Metodo per la terminazione di polimeri viventi ottenuti per polimerizzazione anionica di monomeri dienici e/o vinilaromatici e composti adatti allo scopo.
DE69405839D1 (de) Superabsorbierende Acryl-Polymere mit verbesserten Eigenschaften und Verfahren zu deren Herstellung
ES2116606T3 (es) Recubrimientos de superficie polimericos.
IT1204812B (it) Procedimento per la fabbricazione di una vetrata di sicurezza per autoveicoli ed edifici,e prodotto cosi' ottenuto
JPH1158612A (ja) 異材合せガラス板及びその製造方法
EP0821014A3 (de) Vinylchlorid-Polymerisation
ATE56978T1 (de) Verfahren zur kupplung von lebenden polymeren erhalten durch anionische polymerisation.
DE3782776D1 (de) Verfahren fuer die anionische polymerisation von caprolactam sowie fuer dessen copolymerisation mit anderen lactamen.
WO2000077079A3 (en) Reactive adhesives and coatings with trifunctional olefinic monomers
ATE128148T1 (de) Klebstoffemulsionen, verfahren zu ihrer herstellung und ihre anwendung.
ATE103239T1 (de) Klebstoffschicht fuer die herstellung von geschichtetem glas, verfahren fuer die herstellung von geschichtetem glas mit einer solchen schicht.
JPH047065A (ja) 北硬化性塗料の塗布方法
EP0596106A4 (de) Verfahren zur herstellung von trägen für die kationaustausch-flüssigchromatographie sowie verfahren zur quantitativen bestimmung von gezuchertem hämogloben unter benutzung dieses trägers.
JPS58119859A (ja) 合成樹脂積層体の製造方法