ATE541577T1 - Metallo-fullerenole und ihre anwendung bei der herstellung von medikamenten zur hemmung des tumorwachstums - Google Patents

Metallo-fullerenole und ihre anwendung bei der herstellung von medikamenten zur hemmung des tumorwachstums

Info

Publication number
ATE541577T1
ATE541577T1 AT06791004T AT06791004T ATE541577T1 AT E541577 T1 ATE541577 T1 AT E541577T1 AT 06791004 T AT06791004 T AT 06791004T AT 06791004 T AT06791004 T AT 06791004T AT E541577 T1 ATE541577 T1 AT E541577T1
Authority
AT
Austria
Prior art keywords
application
fullerenols
metallo
medications
production
Prior art date
Application number
AT06791004T
Other languages
English (en)
Inventor
Yuliang Zhao
Chunying Chen
Gengmei Xing
Original Assignee
Inst Of High Energy Phys Chinese Acad Of Sc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Of High Energy Phys Chinese Acad Of Sc filed Critical Inst Of High Energy Phys Chinese Acad Of Sc
Application granted granted Critical
Publication of ATE541577T1 publication Critical patent/ATE541577T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/244—Lanthanides; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/734—Fullerenes, i.e. graphene-based structures, such as nanohorns, nanococoons, nanoscrolls or fullerene-like structures, e.g. WS2 or MoS2 chalcogenide nanotubes, planar C3N4, etc.
    • Y10S977/735—Carbon buckyball
    • Y10S977/736—Carbon buckyball having atoms interior to the carbon cage
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT06791004T 2005-09-19 2006-09-15 Metallo-fullerenole und ihre anwendung bei der herstellung von medikamenten zur hemmung des tumorwachstums ATE541577T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNA2005101034947A CN1739562A (zh) 2005-09-19 2005-09-19 金属富勒醇在抑制肿瘤生长中的应用
PCT/CN2006/002405 WO2007033578A1 (en) 2005-09-19 2006-09-15 Metallo-fullerenols and its application in preparation of medicines for inhibiting the growth of tumour

Publications (1)

Publication Number Publication Date
ATE541577T1 true ATE541577T1 (de) 2012-02-15

Family

ID=36092186

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06791004T ATE541577T1 (de) 2005-09-19 2006-09-15 Metallo-fullerenole und ihre anwendung bei der herstellung von medikamenten zur hemmung des tumorwachstums

Country Status (6)

Country Link
US (1) US8124657B2 (de)
EP (1) EP1941887B1 (de)
JP (1) JP5043015B2 (de)
CN (1) CN1739562A (de)
AT (1) ATE541577T1 (de)
WO (1) WO2007033578A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8808861B2 (en) 2010-11-18 2014-08-19 The Ohio State University Laminate composite and method for making same
US9085463B2 (en) 2011-01-17 2015-07-21 Marelle, Llc Water-soluble functionalized fullerenes
CN102488657B (zh) * 2011-12-23 2014-05-14 苏州大学 富勒醇固体脂质纳米粒及其制备和应用
CN104127872B (zh) * 2014-07-29 2016-05-25 北京福纳康生物技术有限公司 金属富勒烯单晶纳米颗粒在制备特异性肿瘤血管阻断剂中的应用
CA2940611C (en) * 2014-07-29 2020-12-01 Beijing Fullcan Bio-Technology Co., Ltd. A method for the treatment of cancer based on metallofullerene monocrystalline nanoparticles specifically disrupting tumor vessels
CN107753513A (zh) * 2016-08-15 2018-03-06 北京福纳康生物技术有限公司 富勒烯在制备药物中的用途以及保护肝脏的药物
RU2659972C1 (ru) * 2016-12-23 2018-07-04 Федеральное государственное бюджетное учреждение "Петербургский институт ядерной физики им. Б.П. Константинова" (ФГБУ "ПИЯФ") Способ получения водорастворимых гидроксилированных производных эндометаллофуллеренов лантаноидов
EP3576798B1 (de) * 2017-02-02 2023-07-26 The Cleveland Clinic Foundation Verfahren zur herstellung von metall - funktionalisierter fullerene nanoverbundstoff
CN108853142A (zh) * 2017-05-09 2018-11-23 北京福纳康生物技术有限公司 水溶性富勒烯纳米颗粒在制备抑制肿瘤生长药物中的应用
CN107693540A (zh) * 2017-10-12 2018-02-16 浙江理工大学 金属富勒醇及其作为制备治疗白血病药物的应用
CN115645437A (zh) * 2022-09-26 2023-01-31 中国科学院化学研究所 富勒烯制剂在制备治疗肠道癌症的药物中的应用
CN118846082A (zh) * 2024-07-12 2024-10-29 中国科学院化学研究所 一种羟基富勒烯材料和mTOR抑制剂联合使用在制备治疗肿瘤药物的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648523A (en) * 1995-10-26 1997-07-15 Chiang Long Y Fullerene derivatives as free-radical scavengers
JP2001114713A (ja) * 1999-10-15 2001-04-24 Schering Ag ガドリニウム内包フラロールおよびその造影剤としての使用
AU2001289127A1 (en) * 2000-09-21 2002-04-02 Long Y. Chiang Tumor treatment
CN1208338C (zh) * 2002-10-23 2005-06-29 赵宇亮 金属富勒烯磁共振成像造影对比度增强剂及其制备方法和用途
JP2005272350A (ja) * 2004-03-24 2005-10-06 Vitamin C60 Bioresearch Kk 癌転移阻害剤

Also Published As

Publication number Publication date
JP5043015B2 (ja) 2012-10-10
JP2009511432A (ja) 2009-03-19
CN1739562A (zh) 2006-03-01
EP1941887A1 (de) 2008-07-09
EP1941887B1 (de) 2012-01-18
US20090076171A1 (en) 2009-03-19
EP1941887A4 (de) 2010-07-28
US8124657B2 (en) 2012-02-28
WO2007033578A1 (en) 2007-03-29

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