ATE541844T1 - Antivirale verbindungen - Google Patents
Antivirale verbindungenInfo
- Publication number
- ATE541844T1 ATE541844T1 AT06848055T AT06848055T ATE541844T1 AT E541844 T1 ATE541844 T1 AT E541844T1 AT 06848055 T AT06848055 T AT 06848055T AT 06848055 T AT06848055 T AT 06848055T AT E541844 T1 ATE541844 T1 AT E541844T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- antiviral compounds
- hcv
- viral
- syntheses
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75247305P | 2005-12-21 | 2005-12-21 | |
| PCT/US2006/049079 WO2007076034A2 (en) | 2005-12-21 | 2006-12-20 | Anti-viral compounds |
| US11/613,810 US7910595B2 (en) | 2005-12-21 | 2006-12-20 | Anti-viral compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE541844T1 true ATE541844T1 (de) | 2012-02-15 |
Family
ID=38226308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06848055T ATE541844T1 (de) | 2005-12-21 | 2006-12-20 | Antivirale verbindungen |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7910595B2 (de) |
| EP (1) | EP1979348B1 (de) |
| JP (1) | JP2009521479A (de) |
| KR (1) | KR20080080395A (de) |
| CN (1) | CN102702193A (de) |
| AT (1) | ATE541844T1 (de) |
| AU (1) | AU2006330924B2 (de) |
| CA (1) | CA2633757A1 (de) |
| ES (1) | ES2378473T3 (de) |
| IL (1) | IL192306A0 (de) |
| NZ (1) | NZ569817A (de) |
| RU (1) | RU2441869C2 (de) |
| WO (1) | WO2007076034A2 (de) |
| ZA (1) | ZA200805304B (de) |
Families Citing this family (89)
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| US7964580B2 (en) | 2007-03-30 | 2011-06-21 | Pharmasset, Inc. | Nucleoside phosphoramidate prodrugs |
| EP2178852B9 (de) | 2007-08-03 | 2016-06-22 | Romark Laboratories, L.C. | Alkylsulfonyl-substituierte thiazolidverbindungen |
| CA2727103A1 (en) * | 2008-07-03 | 2010-01-07 | Merck Patent Gmbh | Naphthyridinones as aurora kinase inhibitors |
| EP2303841A1 (de) | 2008-07-14 | 2011-04-06 | Gilead Sciences, Inc. | Oxindolylhemmerverbindungen |
| RU2505539C2 (ru) * | 2008-12-23 | 2014-01-27 | Эбботт Лэборетриз | Антивирусные соединения |
| AR074897A1 (es) | 2008-12-23 | 2011-02-23 | Pharmasset Inc | Fosforamidatos de nucleosidos |
| CN102264737A (zh) * | 2008-12-23 | 2011-11-30 | 雅培制药有限公司 | 抗病毒化合物 |
| MX2011006890A (es) | 2008-12-23 | 2011-07-20 | Pharmasset Inc | Analogos de nucleosidos. |
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| TWI438200B (zh) | 2009-02-17 | 2014-05-21 | 必治妥美雅史谷比公司 | Ｃ型肝炎病毒抑制劑 |
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| RU2552533C2 (ru) * | 2009-03-25 | 2015-06-10 | Эббви Инк. | Противовирусные соединения и их применения |
| US8796466B2 (en) | 2009-03-30 | 2014-08-05 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| WO2010114881A1 (en) * | 2009-04-01 | 2010-10-07 | Progenra Inc. | Anti-neoplastic compounds, compositions and methods |
| US8329907B2 (en) | 2009-04-02 | 2012-12-11 | Merck Patent Gmbh | Autotaxin inhibitors |
| TW201038559A (en) | 2009-04-09 | 2010-11-01 | Bristol Myers Squibb Co | Hepatitis C virus inhibitors |
| US8143414B2 (en) | 2009-04-13 | 2012-03-27 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| WO2010120935A1 (en) | 2009-04-15 | 2010-10-21 | Abbott Laboratories | Anti-viral compounds |
| CN105853415A (zh) * | 2009-05-12 | 2016-08-17 | 罗马克实验室有限公司 | 卤代烷基杂芳基苯甲酰胺化合物 |
| TWI576352B (zh) | 2009-05-20 | 2017-04-01 | 基利法瑪席特有限責任公司 | 核苷磷醯胺 |
| US8618076B2 (en) | 2009-05-20 | 2013-12-31 | Gilead Pharmasset Llc | Nucleoside phosphoramidates |
| US8138215B2 (en) | 2009-05-29 | 2012-03-20 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US8211928B2 (en) | 2009-05-29 | 2012-07-03 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| ES2463826T3 (es) | 2009-06-08 | 2014-05-29 | Gilead Sciences, Inc. | Compuestos inhibidores de HDAC de cicloalquilcarbamato benzamida anilina |
| CA2763786C (en) | 2009-06-08 | 2014-09-30 | Gilead Sciences, Inc. | Alkanoylamino benzamide aniline hdac inihibitor compounds |
| US8937150B2 (en) | 2009-06-11 | 2015-01-20 | Abbvie Inc. | Anti-viral compounds |
| US9394279B2 (en) | 2009-06-11 | 2016-07-19 | Abbvie Inc. | Anti-viral compounds |
| US8716454B2 (en) | 2009-06-11 | 2014-05-06 | Abbvie Inc. | Solid compositions |
| EP2853531A3 (de) | 2009-06-11 | 2015-08-12 | AbbVie Bahamas Ltd. | Antivirale Verbindungen |
| BRPI1014322A2 (pt) | 2009-06-26 | 2015-08-25 | Romark Lab Lc | Método para tratar infecção, e para interromper ou evitar a produção de partículas virais infecciosas, combinação, e, composição farmacêutica. |
| WO2011046991A2 (en) * | 2009-10-15 | 2011-04-21 | Gilead Connecticut, Inc. | Certain substituted ureas as modulators of kinase activity |
| US20110269956A1 (en) | 2009-11-11 | 2011-11-03 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US20110274648A1 (en) | 2009-11-11 | 2011-11-10 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US20110281910A1 (en) | 2009-11-12 | 2011-11-17 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US20110137633A1 (en) * | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Anti-viral compounds and methods of identifying the same |
| US8377980B2 (en) | 2009-12-16 | 2013-02-19 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US8362020B2 (en) | 2009-12-30 | 2013-01-29 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| AP2012006535A0 (en) | 2010-03-31 | 2012-10-31 | Gilead Pharmasset Llc | Stereoselective synthesis of phosphorous containing actives |
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| NZ605440A (en) | 2010-06-10 | 2014-05-30 | Abbvie Bahamas Ltd | Solid compositions comprising an hcv inhibitor |
| JP5872552B2 (ja) | 2010-07-09 | 2016-03-01 | ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ | 化学化合物 |
| CA2808841A1 (en) * | 2010-08-24 | 2012-03-01 | Brigham Young University | Antimetastatic compounds |
| ES2716158T3 (es) | 2010-11-30 | 2019-06-10 | Gilead Pharmasset Llc | 2'-spiro-nucleótidos para el tratamiento de hepatitis C |
| US8552047B2 (en) | 2011-02-07 | 2013-10-08 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US9546160B2 (en) | 2011-05-12 | 2017-01-17 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
| HRP20180237T4 (hr) | 2011-09-16 | 2020-12-11 | Gilead Pharmasset Llc | Metode za liječenje hcv-a |
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| US9034832B2 (en) | 2011-12-29 | 2015-05-19 | Abbvie Inc. | Solid compositions |
| US9326973B2 (en) | 2012-01-13 | 2016-05-03 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
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| EP2950786B1 (de) | 2013-01-31 | 2019-11-27 | Gilead Pharmasset LLC | Kombinationsformulierung zweier antiviraler verbindungen |
| US11484534B2 (en) | 2013-03-14 | 2022-11-01 | Abbvie Inc. | Methods for treating HCV |
| US9717712B2 (en) | 2013-07-02 | 2017-08-01 | Bristol-Myers Squibb Company | Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus |
| US20150023913A1 (en) | 2013-07-02 | 2015-01-22 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| JP2016527232A (ja) | 2013-07-17 | 2016-09-08 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | Ｈｃｖの治療に使用するためのビフェニル誘導体を含む組み合わせ |
| EA201690473A1 (ru) | 2013-08-27 | 2017-03-31 | ГАЙЛИД ФАРМАССЕТ ЭлЭлСи | Комбинированный состав двух противовирусных соединений |
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| KR101823488B1 (ko) | 2013-10-14 | 2018-01-30 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 선택적으로 치환된 퀴놀린 화합물 |
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-
2006
- 2006-12-20 AT AT06848055T patent/ATE541844T1/de active
- 2006-12-20 WO PCT/US2006/049079 patent/WO2007076034A2/en not_active Ceased
- 2006-12-20 NZ NZ569817A patent/NZ569817A/en not_active IP Right Cessation
- 2006-12-20 AU AU2006330924A patent/AU2006330924B2/en not_active Ceased
- 2006-12-20 CN CN2012101573389A patent/CN102702193A/zh active Pending
- 2006-12-20 KR KR1020087017660A patent/KR20080080395A/ko not_active Ceased
- 2006-12-20 EP EP06848055A patent/EP1979348B1/de active Active
- 2006-12-20 ES ES06848055T patent/ES2378473T3/es active Active
- 2006-12-20 JP JP2008547624A patent/JP2009521479A/ja not_active Ceased
- 2006-12-20 US US11/613,810 patent/US7910595B2/en active Active
- 2006-12-20 RU RU2008129810/04A patent/RU2441869C2/ru not_active IP Right Cessation
- 2006-12-20 CA CA002633757A patent/CA2633757A1/en not_active Abandoned
-
2008
- 2008-06-18 ZA ZA2008/05304A patent/ZA200805304B/en unknown
- 2008-06-19 IL IL192306A patent/IL192306A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US7910595B2 (en) | 2011-03-22 |
| RU2441869C2 (ru) | 2012-02-10 |
| ES2378473T3 (es) | 2012-04-12 |
| KR20080080395A (ko) | 2008-09-03 |
| US20070232627A1 (en) | 2007-10-04 |
| EP1979348A2 (de) | 2008-10-15 |
| ZA200805304B (en) | 2012-01-25 |
| CA2633757A1 (en) | 2007-07-05 |
| EP1979348B1 (de) | 2012-01-18 |
| NZ569817A (en) | 2011-10-28 |
| CN102702193A (zh) | 2012-10-03 |
| HK1122291A1 (en) | 2009-05-15 |
| JP2009521479A (ja) | 2009-06-04 |
| AU2006330924A1 (en) | 2007-07-05 |
| IL192306A0 (en) | 2008-12-29 |
| RU2008129810A (ru) | 2010-01-27 |
| WO2007076034A3 (en) | 2007-10-04 |
| AU2006330924B2 (en) | 2012-03-15 |
| WO2007076034A2 (en) | 2007-07-05 |
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