ATE541855T1 - Weitere kristalline formen von rostafuroxin - Google Patents
Weitere kristalline formen von rostafuroxinInfo
- Publication number
- ATE541855T1 ATE541855T1 AT06819722T AT06819722T ATE541855T1 AT E541855 T1 ATE541855 T1 AT E541855T1 AT 06819722 T AT06819722 T AT 06819722T AT 06819722 T AT06819722 T AT 06819722T AT E541855 T1 ATE541855 T1 AT E541855T1
- Authority
- AT
- Austria
- Prior art keywords
- crystalline forms
- rostafuroxin
- forms
- βandrostane
- triol
- Prior art date
Links
- AEAPORIZZWBIEX-DTBDINHYSA-N (3s,5r,8r,9s,10s,13s,14s,17s)-17-(furan-3-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,15,16-dodecahydro-1h-cyclopenta[a]phenanthrene-3,14,17-triol Chemical compound C=1([C@@]2(O)CC[C@]3(O)[C@H]4[C@@H]([C@]5(CC[C@H](O)C[C@H]5CC4)C)CC[C@@]32C)C=COC=1 AEAPORIZZWBIEX-DTBDINHYSA-N 0.000 title 1
- 229950005768 rostafuroxin Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05025817 | 2005-11-25 | ||
| PCT/EP2006/068845 WO2007060206A2 (en) | 2005-11-25 | 2006-11-23 | Further crystalline forms of rostafuroxin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE541855T1 true ATE541855T1 (de) | 2012-02-15 |
Family
ID=36165370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06819722T ATE541855T1 (de) | 2005-11-25 | 2006-11-23 | Weitere kristalline formen von rostafuroxin |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9127037B2 (de) |
| EP (1) | EP1951738B1 (de) |
| AT (1) | ATE541855T1 (de) |
| CY (1) | CY1112973T1 (de) |
| DK (1) | DK1951738T3 (de) |
| ES (1) | ES2380491T3 (de) |
| PL (1) | PL1951738T3 (de) |
| PT (1) | PT1951738E (de) |
| SI (1) | SI1951738T1 (de) |
| WO (1) | WO2007060206A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010149666A1 (en) | 2009-06-22 | 2010-12-29 | Medexis S.A. | Methods for treating neoplasia |
| EP2490694B1 (de) * | 2009-10-19 | 2015-09-16 | Rostaquo S.p.A. | Rostafuroxin zur pharmakogenomischen behandlung von herz-krleislauf-erkrankungen |
| WO2012066141A1 (en) | 2010-11-19 | 2012-05-24 | Fondazione Centro San Raffaele Del Monte Tabor | Markers for acute kidney injury and uses thereof |
| CN102940640A (zh) * | 2012-12-06 | 2013-02-27 | 中国生命药物治疗有限公司 | 罗他夫辛在制备治疗基因缺陷型原发性高血压的药物中的用途 |
| CN108096207B (zh) * | 2017-12-29 | 2021-01-01 | 兆科药业(合肥)有限公司 | 一种罗他夫辛肠溶片的制备方法 |
| US11337988B2 (en) | 2018-09-27 | 2022-05-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of ouabain antagonists to inhibit viral infection |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4221636C1 (de) * | 1992-07-01 | 1994-03-31 | Sigma Tau Ind Farmaceuti | Cyclopentanperhydrophenanthren-17beta-(3-furyl)-3-Derivate |
| DE4227616C2 (de) * | 1992-08-20 | 1995-04-13 | Sigma Tau Ind Farmaceuti | 17-(3-Furyl)-und 17-(4-Pyridazinyl)-5beta, 14beta-androstanderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammemsetzungen |
| IT1282286B1 (it) * | 1995-05-11 | 1998-03-16 | Sigma Tau Ind Farmaceuti | Seco-d steroidi sul sistema cardiovascolare, processi per la loro preparazione e composizioni farmaceutiche che li contengono. |
-
2006
- 2006-11-23 US US12/094,885 patent/US9127037B2/en not_active Expired - Fee Related
- 2006-11-23 SI SI200631302T patent/SI1951738T1/sl unknown
- 2006-11-23 EP EP06819722A patent/EP1951738B1/de not_active Not-in-force
- 2006-11-23 AT AT06819722T patent/ATE541855T1/de active
- 2006-11-23 ES ES06819722T patent/ES2380491T3/es active Active
- 2006-11-23 PL PL06819722T patent/PL1951738T3/pl unknown
- 2006-11-23 WO PCT/EP2006/068845 patent/WO2007060206A2/en not_active Ceased
- 2006-11-23 PT PT06819722T patent/PT1951738E/pt unknown
- 2006-11-23 DK DK06819722.7T patent/DK1951738T3/da active
-
2012
- 2012-04-03 CY CY20121100330T patent/CY1112973T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1951738T3 (da) | 2012-04-23 |
| PL1951738T3 (pl) | 2012-06-29 |
| CY1112973T1 (el) | 2016-04-13 |
| ES2380491T3 (es) | 2012-05-14 |
| WO2007060206A3 (en) | 2007-08-30 |
| SI1951738T1 (sl) | 2012-06-29 |
| WO2007060206A2 (en) | 2007-05-31 |
| PT1951738E (pt) | 2012-04-18 |
| EP1951738B1 (de) | 2012-01-18 |
| EP1951738A2 (de) | 2008-08-06 |
| US20080300228A1 (en) | 2008-12-04 |
| US9127037B2 (en) | 2015-09-08 |
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