ATE543496T1 - 3-acylindol-derivate sowie deren herstellung und therapeutische anwendung - Google Patents

3-acylindol-derivate sowie deren herstellung und therapeutische anwendung

Info

Publication number: ATE543496T1
Authority: AT; Austria
Prior art keywords: production; therapeutic use; acylindole derivatives; acylindole; derivatives
Prior art date: 2005-11-18

Application number

AT06841810T

Other languages

English (en)

Inventor

Francis Barth

Claude Vernhet

Murielle Rinaldi-Carmona

Carole Guillaumont-Legeay

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-11-18

Filing date

2006-11-17

Publication date

2012-02-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36619225&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE543496(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-11-17 Application filed by Sanofi Sa filed Critical Sanofi Sa

2012-02-15 Application granted granted Critical

2012-02-15 Publication of ATE543496T1 publication Critical patent/ATE543496T1/de

Links

230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Communicable Diseases (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Oncology (AREA)
Endocrinology (AREA)
Transplantation (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Child & Adolescent Psychology (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Pulmonology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)

AT06841810T 2005-11-18 2006-11-17 3-acylindol-derivate sowie deren herstellung und therapeutische anwendung ATE543496T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0511740A FR2893615B1 (fr)	2005-11-18	2005-11-18	Derives de 3-acylindole, leur preparation et leur application en therapeutique
PCT/FR2006/002535 WO2007057571A2 (fr)	2005-11-18	2006-11-17	Derives de 3-acylindole, leur preparation et leur application en therapeutique comme modulateurs pour les recepteurs cb2

Publications (1)

Publication Number	Publication Date
ATE543496T1 true ATE543496T1 (de)	2012-02-15

Family

ID=36619225

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06841810T ATE543496T1 (de)	2005-11-18	2006-11-17	3-acylindol-derivate sowie deren herstellung und therapeutische anwendung

Country Status (9)

Country	Link
US (1)	US7741363B2 (de)
EP (1)	EP1951225B1 (de)
JP (1)	JP5106410B2 (de)
AR (1)	AR057898A1 (de)
AT (1)	ATE543496T1 (de)
FR (1)	FR2893615B1 (de)
TW (1)	TW200738628A (de)
UY (1)	UY29921A1 (de)
WO (1)	WO2007057571A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2950055A1 (fr)	2009-09-17	2011-03-18	Sanofi Aventis	Derives de 3-amino-cinnolin-4(1h)-one substitues, leur preparation et leur application en therapeutique
FR2983859B1 (fr)	2011-12-12	2014-01-17	Sanofi Sa	Derives de 1,3,5-triazine-2-amine, leur preparation et leur application en diagnostique et en therapeutique
US20230416291A1 (en) *	2020-11-27	2023-12-28	Mirailab Bioscience Inc.	HIGH-PURITY ß-NICOTINAMIDE MONONUCLEOTIDE (NMN) AND METHOD FOR PRODUCING SAME

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4581354A (en)	1984-08-06	1986-04-08	Sterling Drug Inc.	3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use
CA2036307C (en) *	1990-03-08	2002-07-09	Susan Jean Ward	3-arylcarbonyl-1-aminoalkyl-1h-indole-containing antiglaucoma compositions and method
GB9115951D0 (en) *	1991-07-24	1991-09-11	Pfizer Ltd	Indoles
US5532237A (en) *	1995-02-15	1996-07-02	Merck Frosst Canada, Inc.	Indole derivatives with affinity for the cannabinoid receptor
FR2735774B1 (fr)	1995-06-21	1997-09-12	Sanofi Sa	Utilisation de composes agonistes du recepteur cb2 humain pour la preparation de medicaments immunomodulateurs, nouveaux composes agonistes du recepteur cb2 et les compositions pharmaceutiques les contenant
FR2816938B1 (fr) *	2000-11-22	2003-01-03	Sanofi Synthelabo	Derives de 3-aroylindole, leur procede de preparation et les compositions pharmaceutiques en contenant
JP2005503998A (ja) *	2001-01-29	2005-02-10	ユニバーシティオブコネチカット	受容体選択性のカンナビミメティックアミノアルキルインドール
FR2839718B1 (fr) *	2002-05-17	2004-06-25	Sanofi Synthelabo	Derives d'indole, leur procede de preparation et les compositions pharmaceutiques en contenant
FR2847899B1 (fr) *	2002-11-29	2006-04-28	Sanofi Synthelabo	Derives d'indole-3-carboxamide, leur preparation et leur application en therapeutique
WO2005056522A2 (en) *	2003-12-04	2005-06-23	National Health Research Institutes	Indole compounds
TW200522944A (en) *	2003-12-23	2005-07-16	Lilly Co Eli	CB1 modulator compounds
JP4922946B2 (ja)	2004-12-21	2012-04-25	アボット・ラボラトリーズ	カンナビノイド受容体リガンドとしての３−シクロアルキルカルボニルインドール類

2005
- 2005-11-18 FR FR0511740A patent/FR2893615B1/fr not_active Expired - Fee Related
2006
- 2006-11-17 AT AT06841810T patent/ATE543496T1/de active
- 2006-11-17 JP JP2008540656A patent/JP5106410B2/ja not_active Expired - Fee Related
- 2006-11-17 AR ARP060105044A patent/AR057898A1/es not_active Application Discontinuation
- 2006-11-17 EP EP06841810A patent/EP1951225B1/de active Active
- 2006-11-17 WO PCT/FR2006/002535 patent/WO2007057571A2/fr not_active Ceased
- 2006-11-17 UY UY29921A patent/UY29921A1/es unknown
- 2006-11-17 TW TW095142655A patent/TW200738628A/zh unknown
2008
- 2008-05-14 US US12/120,509 patent/US7741363B2/en active Active

Also Published As

Publication number	Publication date
JP5106410B2 (ja)	2012-12-26
JP2009515935A (ja)	2009-04-16
US20080275102A1 (en)	2008-11-06
FR2893615B1 (fr)	2008-03-07
FR2893615A1 (fr)	2007-05-25
TW200738628A (en)	2007-10-16
EP1951225A2 (de)	2008-08-06
US7741363B2 (en)	2010-06-22
WO2007057571A3 (fr)	2007-07-12
AR057898A1 (es)	2007-12-26
WO2007057571A2 (fr)	2007-05-24
EP1951225B1 (de)	2012-02-01
UY29921A1 (es)	2007-06-29

Publication	Publication Date	Title
ATE453637T1 (de)	2010-01-15	N-(aminoheteroaryl)-1h-indol-2-carboxamid- derivate sowie deren herstellung und therapeutische anwendung
ATE372998T1 (de)	2007-09-15	1-aminophthalazinderivate, deren herstellung und deren therapeutische verwendung
ATE395342T1 (de)	2008-05-15	2-carbamid-4-phenylthiazol-derivate, deren herstellung und therapeutische verwendung
ATE461930T1 (de)	2010-04-15	Harnstoffderivate von tropan, ihre herstellung und ihre therapeutische anwendung
ATE441635T1 (de)	2009-09-15	4-cyanopyrazol-3-carbonsäureamidderivate, herstellung und therapeutische anwendung davon
ATE469131T1 (de)	2010-06-15	Sulfonamidderivate, ihre herstellung und ihre therapeutische anwendung
ATE467633T1 (de)	2010-05-15	2-aryl-6-phenylimidazoä1,2-aüpyridin-derivate, ihre herstellung und therapeutische verwendung
ATE475661T1 (de)	2010-08-15	Triazolopyridin-carboxamid-derivate sowie ihre herstellung und therapeutische verwendung
ATE336491T1 (de)	2006-09-15	Piperazinylacylpiperidinderivate, deren herstellung und deren therapeutische anwendung
ATE412635T1 (de)	2008-11-15	Diphenylpyridinderivate, deren herstellung und deren therapeutische anwendung
ATE409184T1 (de)	2008-10-15	Dioxan-2-alkylkarbamaten derivaten, deren herstellung und deren therapeutischen verwendung
ATE512970T1 (de)	2011-07-15	Dimere von artemisininderivaten, deren herstellung und deren therapeutische verwendung
ATE548349T1 (de)	2012-03-15	In stellung 3 disubstituierte indol-2-on- pyridinderivate, ihre herstellung sowie ihre therapeutische anwendung
ATE502035T1 (de)	2011-04-15	2-amido-4-phenylthiazol-derivate, ihre herstellung und ihre therapeutische verwendung
ATE459608T1 (de)	2010-03-15	Oxopiperidinderivate, ihre herstellung und therapeutische verwendung
ATE423119T1 (de)	2009-03-15	Pyridoä2,3-düpyrimidin-derivate sowie deren herstellung und therapeutische anwendung
ATE420081T1 (de)	2009-01-15	Trifluormethylbenzamidderivate und therapeutische verwendungen dafür
ATE499351T1 (de)	2011-03-15	Aryl- und heteroaryl-ethyl-acylguanidinderivate, ihre herstellung und ihre therapeutische anwendung
ATE542806T1 (de)	2012-02-15	Diarylmethylpiperazinderivate, deren herstellung und deren verwendung
DE602006017183D1 (de)	2010-11-11	Benzimidazolderivat und anwendung davon
PL377180A1 (pl)	2007-04-02	Zastosowanie izoflawonów i ich pochodnych w leczeniu mukopolisacharydoz
ATE417846T1 (de)	2009-01-15	Aminotropanderivate, deren herstellung und deren therapeutische verwendung
ATE529426T1 (de)	2011-11-15	N-phenyl-imidazo(1,2-a)pyridincarboxamid- verbindungen, ihre herstellung sowie ihre therapeutische anwendung
DE602006015675D1 (de)	2010-09-02	6-heteroarylpyridoindolon-derivate, ihre herstellung und ihre therapeutische anwendung
ATE448211T1 (de)	2009-11-15	1,2,4-triazinderivate, ihre herstellung und ihre verwendung in der humantherapie