ATE543496T1 - 3-acylindol-derivate sowie deren herstellung und therapeutische anwendung - Google Patents

3-acylindol-derivate sowie deren herstellung und therapeutische anwendung

Info

Publication number: ATE543496T1
Authority: AT; Austria
Prior art keywords: production; therapeutic use; acylindole derivatives; acylindole; derivatives
Prior art date: 2005-11-18

Application number

AT06841810T

Other languages

English (en)

Inventor

Francis Barth

Claude Vernhet

Murielle Rinaldi-Carmona

Carole Guillaumont-Legeay

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-11-18

Filing date

2006-11-17

Publication date

2012-02-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36619225&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE543496(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-11-17 Application filed by Sanofi Sa filed Critical Sanofi Sa

2012-02-15 Application granted granted Critical

2012-02-15 Publication of ATE543496T1 publication Critical patent/ATE543496T1/de

Links

230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Emergency Medicine (AREA)
Transplantation (AREA)
Child & Adolescent Psychology (AREA)
Endocrinology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)

AT06841810T 2005-11-18 2006-11-17 3-acylindol-derivate sowie deren herstellung und therapeutische anwendung ATE543496T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0511740A FR2893615B1 (fr)	2005-11-18	2005-11-18	Derives de 3-acylindole, leur preparation et leur application en therapeutique
PCT/FR2006/002535 WO2007057571A2 (fr)	2005-11-18	2006-11-17	Derives de 3-acylindole, leur preparation et leur application en therapeutique comme modulateurs pour les recepteurs cb2

Publications (1)

Publication Number	Publication Date
ATE543496T1 true ATE543496T1 (de)	2012-02-15

Family

ID=36619225

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06841810T ATE543496T1 (de)	2005-11-18	2006-11-17	3-acylindol-derivate sowie deren herstellung und therapeutische anwendung

Country Status (9)

Country	Link
US (1)	US7741363B2 (de)
EP (1)	EP1951225B1 (de)
JP (1)	JP5106410B2 (de)
AR (1)	AR057898A1 (de)
AT (1)	ATE543496T1 (de)
FR (1)	FR2893615B1 (de)
TW (1)	TW200738628A (de)
UY (1)	UY29921A1 (de)
WO (1)	WO2007057571A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2950055A1 (fr)	2009-09-17	2011-03-18	Sanofi Aventis	Derives de 3-amino-cinnolin-4(1h)-one substitues, leur preparation et leur application en therapeutique
FR2983859B1 (fr)	2011-12-12	2014-01-17	Sanofi Sa	Derives de 1,3,5-triazine-2-amine, leur preparation et leur application en diagnostique et en therapeutique
EP4253396A4 (de) *	2020-11-27	2024-09-11	Mirailab Bioscience Inc.	Hochreines beta-nicotinamid-mononukleotid (nmn) und verfahren zu seiner herstellung

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4581354A (en)	1984-08-06	1986-04-08	Sterling Drug Inc.	3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use
CA2036307C (en) *	1990-03-08	2002-07-09	Susan Jean Ward	3-arylcarbonyl-1-aminoalkyl-1h-indole-containing antiglaucoma compositions and method
GB9115951D0 (en) *	1991-07-24	1991-09-11	Pfizer Ltd	Indoles
US5532237A (en) *	1995-02-15	1996-07-02	Merck Frosst Canada, Inc.	Indole derivatives with affinity for the cannabinoid receptor
FR2735774B1 (fr)	1995-06-21	1997-09-12	Sanofi Sa	Utilisation de composes agonistes du recepteur cb2 humain pour la preparation de medicaments immunomodulateurs, nouveaux composes agonistes du recepteur cb2 et les compositions pharmaceutiques les contenant
FR2816938B1 (fr) *	2000-11-22	2003-01-03	Sanofi Synthelabo	Derives de 3-aroylindole, leur procede de preparation et les compositions pharmaceutiques en contenant
DE60237431D1 (de) *	2001-01-29	2010-10-07	Univ Connecticut	Rezeptor-selektive cannabimimetische aminoalkylindole
FR2839718B1 (fr) *	2002-05-17	2004-06-25	Sanofi Synthelabo	Derives d'indole, leur procede de preparation et les compositions pharmaceutiques en contenant
FR2847899B1 (fr) *	2002-11-29	2006-04-28	Sanofi Synthelabo	Derives d'indole-3-carboxamide, leur preparation et leur application en therapeutique
CN1886133B (zh) *	2003-12-04	2010-12-01	财团法人卫生研究院	吲哚化合物
TW200522944A (en) *	2003-12-23	2005-07-16	Lilly Co Eli	CB1 modulator compounds
US7560481B2 (en)	2004-12-21	2009-07-14	Abbott Laboratories	Indoles are cannabinoid receptor ligands

2005
- 2005-11-18 FR FR0511740A patent/FR2893615B1/fr not_active Expired - Fee Related
2006
- 2006-11-17 AR ARP060105044A patent/AR057898A1/es not_active Application Discontinuation
- 2006-11-17 WO PCT/FR2006/002535 patent/WO2007057571A2/fr not_active Ceased
- 2006-11-17 TW TW095142655A patent/TW200738628A/zh unknown
- 2006-11-17 EP EP06841810A patent/EP1951225B1/de active Active
- 2006-11-17 UY UY29921A patent/UY29921A1/es unknown
- 2006-11-17 AT AT06841810T patent/ATE543496T1/de active
- 2006-11-17 JP JP2008540656A patent/JP5106410B2/ja not_active Expired - Fee Related
2008
- 2008-05-14 US US12/120,509 patent/US7741363B2/en active Active

Also Published As

Publication number	Publication date
EP1951225B1 (de)	2012-02-01
JP5106410B2 (ja)	2012-12-26
EP1951225A2 (de)	2008-08-06
US20080275102A1 (en)	2008-11-06
WO2007057571A3 (fr)	2007-07-12
WO2007057571A2 (fr)	2007-05-24
JP2009515935A (ja)	2009-04-16
US7741363B2 (en)	2010-06-22
UY29921A1 (es)	2007-06-29
FR2893615B1 (fr)	2008-03-07
TW200738628A (en)	2007-10-16
AR057898A1 (es)	2007-12-26
FR2893615A1 (fr)	2007-05-25

Publication	Publication Date	Title
ATE453637T1 (de)	2010-01-15	N-(aminoheteroaryl)-1h-indol-2-carboxamid- derivate sowie deren herstellung und therapeutische anwendung
ATE372998T1 (de)	2007-09-15	1-aminophthalazinderivate, deren herstellung und deren therapeutische verwendung
ATE395342T1 (de)	2008-05-15	2-carbamid-4-phenylthiazol-derivate, deren herstellung und therapeutische verwendung
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