ATE543501T1 - Kombination von pemirolast und ramatroban zur verwendung bei der behandlung von entzündlichen erkrankungen - Google Patents
Kombination von pemirolast und ramatroban zur verwendung bei der behandlung von entzündlichen erkrankungenInfo
- Publication number
- ATE543501T1 ATE543501T1 AT07848600T AT07848600T ATE543501T1 AT E543501 T1 ATE543501 T1 AT E543501T1 AT 07848600 T AT07848600 T AT 07848600T AT 07848600 T AT07848600 T AT 07848600T AT E543501 T1 ATE543501 T1 AT E543501T1
- Authority
- AT
- Austria
- Prior art keywords
- ramatroban
- pemirolast
- treatment
- combination
- inflammatory diseases
- Prior art date
Links
- LDXDSHIEDAPSSA-OAHLLOKOSA-N Ramatroban Chemical compound N([C@@H]1CCC=2N(C3=CC=CC=C3C=2C1)CCC(=O)O)S(=O)(=O)C1=CC=C(F)C=C1 LDXDSHIEDAPSSA-OAHLLOKOSA-N 0.000 title abstract 2
- HIANJWSAHKJQTH-UHFFFAOYSA-N pemirolast Chemical compound CC1=CC=CN(C2=O)C1=NC=C2C=1N=NNN=1 HIANJWSAHKJQTH-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004439 pemirolast Drugs 0.000 title abstract 2
- 229950004496 ramatroban Drugs 0.000 title abstract 2
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000012453 solvate Substances 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87585006P | 2006-12-20 | 2006-12-20 | |
| US92962307P | 2007-07-05 | 2007-07-05 | |
| PCT/GB2007/004863 WO2008075028A1 (en) | 2006-12-20 | 2007-12-18 | New combination for use in the treatment of inflammatory disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE543501T1 true ATE543501T1 (de) | 2012-02-15 |
Family
ID=39148805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07848600T ATE543501T1 (de) | 2006-12-20 | 2007-12-18 | Kombination von pemirolast und ramatroban zur verwendung bei der behandlung von entzündlichen erkrankungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20100168137A1 (de) |
| EP (1) | EP2107907B1 (de) |
| AT (1) | ATE543501T1 (de) |
| AU (1) | AU2007336077A1 (de) |
| CA (1) | CA2673214A1 (de) |
| ES (1) | ES2395120T3 (de) |
| WO (1) | WO2008075028A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2443120B1 (de) | 2009-06-16 | 2016-11-02 | RSPR Pharma AB | Kristalline form von pemirolast |
| MX2012005513A (es) * | 2009-11-13 | 2012-06-19 | Cardoz Ab | Pemirolast para el tratamiento de inflamacion sistemica de bajo grado. |
| ES2991300T3 (es) * | 2015-02-13 | 2024-12-03 | Inserm Institut Nat De La Sante Et De Larecherche Medicale | Antagonistas de PTGDR-1 y/o PTGDR-2 para prevenir y/o tratar lupus eritematoso sistémico |
| KR20220164000A (ko) * | 2020-03-31 | 2022-12-12 | 어플라이드 메디칼 테크놀로지스 엘엘씨 | Pgd2/dp2 및 트롬복산 a2/tp 수용체의 이중 길항제 및 이상 면역 반응 또는 혈전성 체질의 치료를 위한 이의 용도 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4122274A (en) * | 1977-05-25 | 1978-10-24 | Bristol-Myers Company | 3-Tetrazolo-5,6,7,8-substituted-pyrido[1,2-a]pyrimidin-4-ones |
| DE3631824A1 (de) * | 1986-02-21 | 1988-03-31 | Bayer Ag | Cycloalkano(1.2-b)indol-sulfonamide |
| JP2504788B2 (ja) * | 1987-11-10 | 1996-06-05 | 東京田辺製薬株式会社 | ９−メチル−３−（１Ｈ−テトラゾ―ル−５−イル）−４Ｈ−ピリド［１，２−ａ］ピリミジン−４−オンカリウム塩の水性製剤 |
| DE69516519T2 (de) * | 1994-05-31 | 2000-10-12 | Mitsubishi-Tokyo Pharmaceuticals, Inc. | Wirkstoff gegen arteriosklerose |
| CN1219872A (zh) * | 1996-05-24 | 1999-06-16 | 血管技术药物公司 | 治疗或预防身体通道疾病的组合物和方法 |
| DE19757983A1 (de) * | 1997-12-24 | 1999-07-01 | Bayer Yakuhin Ltd | Thermodynamisch stabile Form von (r)-3[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazol-0-propansäure (Ramatroban) |
| WO2001021259A2 (en) * | 1999-09-21 | 2001-03-29 | Emory University | Use and compositions for treating platelet-related disorders using anagrelide |
| ITMI20011764A1 (it) * | 2001-08-10 | 2003-02-10 | Dinamite Dipharma Spa | Metodo per l'ottenimento del pemirolast ad elevata purezza |
| EP1550461A1 (de) * | 2002-06-26 | 2005-07-06 | Ono Pharmaceutical Co., Ltd. | Mittel zur behandlung chronischer erkrankungen |
| US7985422B2 (en) * | 2002-08-05 | 2011-07-26 | Torrent Pharmaceuticals Limited | Dosage form |
| WO2004031118A1 (ja) * | 2002-10-03 | 2004-04-15 | Ono Pharmaceutical Co., Ltd. | Ｌｐａ受容体拮抗剤 |
| US8277831B2 (en) * | 2004-02-17 | 2012-10-02 | Advanced Technologies And Regenerative Medicine, Llc. | Drug-enhanced adhesion prevention |
| US7803838B2 (en) * | 2004-06-04 | 2010-09-28 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
| US7202325B2 (en) * | 2005-01-14 | 2007-04-10 | Advanced Cardiovascular Systems, Inc. | Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles |
| US20070225301A1 (en) * | 2006-02-13 | 2007-09-27 | Astion Inflammation Aps | Treatment of acne and other diseases |
| US8445437B2 (en) * | 2006-07-27 | 2013-05-21 | The Brigham And Women's Hospital, Inc. | Treatment and prevention of cardiovascular disease using mast cell stabilizers |
| AR065194A1 (es) * | 2007-02-05 | 2009-05-20 | Xenon Pharmaceuticals Inc | Compuestos de piridopirimidinona de utilidad en el tratamiento de enfermedades o condiciones patologicas mediadas por los canales de sodio |
| US20090012136A1 (en) * | 2007-05-03 | 2009-01-08 | Portola Pharmaceuticals, Inc. | Unit dose formulations and methods of treating and preventing thrombosis with thromboxane receptor antagonists |
-
2007
- 2007-12-18 CA CA002673214A patent/CA2673214A1/en not_active Abandoned
- 2007-12-18 US US12/448,323 patent/US20100168137A1/en not_active Abandoned
- 2007-12-18 AU AU2007336077A patent/AU2007336077A1/en not_active Abandoned
- 2007-12-18 AT AT07848600T patent/ATE543501T1/de active
- 2007-12-18 WO PCT/GB2007/004863 patent/WO2008075028A1/en not_active Ceased
- 2007-12-18 ES ES07848600T patent/ES2395120T3/es active Active
- 2007-12-18 EP EP07848600A patent/EP2107907B1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20100168137A1 (en) | 2010-07-01 |
| ES2395120T3 (es) | 2013-02-08 |
| EP2107907A1 (de) | 2009-10-14 |
| WO2008075028A1 (en) | 2008-06-26 |
| CA2673214A1 (en) | 2008-06-26 |
| EP2107907B1 (de) | 2012-02-01 |
| AU2007336077A1 (en) | 2008-06-26 |
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